Nanocarrier for the enhanced bioavailability of a cardiovascular agent: In vitro, pharmacodynamic, pharmacokinetic and stability assessment

International Journal of Pharmaceutics

Volumn 403, Issue 1-2, 2011, Pages 46-56

  Bali, Vikas ^a   Ali, Mushir ^a   Ali, Javed ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Ezetimibe; Nanoemulsion; Oral bioavailability; Pseudoternary phase diagram; Stability

Indexed keywords

CAPRYOL 90; CHOLESTEROL; COCONUT OIL; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; EZETIMIBE; NANOCARRIER; SURFACTANT; UNCLASSIFIED DRUG; WATER; AZETIDINE DERIVATIVE; CARDIOVASCULAR AGENT; DRUG CARRIER; HYPOCHOLESTEROLEMIC AGENT; NANOMATERIAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG STABILITY; HYPERCHOLESTEROLEMIA; MAXIMUM PLASMA CONCENTRATION; NANOEMULSION; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; REFRACTION INDEX; SHELF LIFE; SUSPENSION; TABLET FORMULATION; THERMODYNAMICS; TIME TO MAXIMUM PLASMA CONCENTRATION; VISCOSITY; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; DRUG STORAGE; EMULSION; SOLUBILITY; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; WISTAR RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AZETIDINES; BIOLOGICAL AVAILABILITY; CARDIOVASCULAR AGENTS; CHOLESTEROL; DRUG CARRIERS; DRUG STABILITY; DRUG STORAGE; EMULSIONS; HYPERCHOLESTEROLEMIA; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSTRUCTURES; PARTICLE SIZE; RATS; RATS, WISTAR; SOLUBILITY; SURFACE PROPERTIES;

EID: 78650168835     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.018     Document Type: Article

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