-
1
-
-
78349310868
-
Self-emulsifying drug delivery systems: An approach to enhance oral bioavailability
-
20727418 10.1016/j.drudis.2010.08.007 1:CAS:528:DC%2BC3cXhsVWmsrfL
-
K Kohli S Chopra D Dhar S Arora RK Khar 2010 Self-emulsifying drug delivery systems: an approach to enhance oral bioavailability Drug Discovery Today 15 21-22 958 965 20727418 10.1016/j.drudis.2010.08.007 1:CAS:528:DC%2BC3cXhsVWmsrfL
-
(2010)
Drug Discovery Today
, vol.15
, Issue.2122
, pp. 958-965
-
-
Kohli, K.1
Chopra, S.2
Dhar, D.3
Arora, S.4
Khar, R.K.5
-
2
-
-
79952224749
-
Oral self-emulsifying drug delivery systems, from biopharmaceutical to technical formulation aspects
-
1:CAS:528:DC%2BC3MXjslClt7k%3D
-
M Kuentz 2011 Oral self-emulsifying drug delivery systems, from biopharmaceutical to technical formulation aspects J Drug Deliv Sci Technol 21 1 17 26 1:CAS:528:DC%2BC3MXjslClt7k%3D
-
(2011)
J Drug Deliv Sci Technol
, vol.21
, Issue.1
, pp. 17-26
-
-
Kuentz, M.1
-
3
-
-
1242291941
-
Drug Solubilization Behavior during in Vitro Digestion of Suspension Formulations of Poorly Water-Soluble Drugs in Triglyceride Lipids
-
DOI 10.1023/B:PHAM.0000016283.87709.a9
-
AM Kaukonen BJ Boyd WN Charman CJ Porter 2004 Drug solubilization behavior during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids Pharm Res 21 2 254 260 15032306 10.1023/B:PHAM.0000016283.87709.a9 1:CAS:528:DC%2BD2cXhtlWqsbo%3D (Pubitemid 38221970)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.2
, pp. 254-260
-
-
Kaukonen, A.M.1
Boyd, B.J.2
Charman, W.N.3
Porter, C.J.H.4
-
4
-
-
0029562489
-
Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
-
DOI 10.1023/A:1016268311867
-
PP Constantinides 1995 Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects Pharm Res 12 11 1561 1572 8592652 10.1023/A:1016268311867 1:CAS:528:DyaK2MXpslCqsrs%3D (Pubitemid 26005509)
-
(1995)
Pharmaceutical Research
, vol.12
, Issue.11
, pp. 1561-1572
-
-
Constantinides, P.P.1
-
5
-
-
0033805858
-
Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems
-
11033431 10.1016/S0928-0987(00)00167-6 1:CAS:528:DC%2BD3cXntF2gur4%3D
-
CW Pouton 2000 Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems Eur J Pharm Sci 11 Suppl 2 S93 S98 11033431 10.1016/S0928-0987(00)00167- 6 1:CAS:528:DC%2BD3cXntF2gur4%3D
-
(2000)
Eur J Pharm Sci
, vol.11
, Issue.SUPPL 2
-
-
Pouton, C.W.1
-
6
-
-
0033812424
-
Lipids, lipophilic drugs, and oral drug delivery-some emerging concepts
-
10906720 10.1002/1520-6017(200008)89:8<967::AID-JPS1>3.0.CO;2-R 1:CAS:528:DC%2BD3cXmtVWms7c%3D
-
WN Charman 2000 Lipids, lipophilic drugs, and oral drug delivery-some emerging concepts J Pharm Sci 89 8 967 978 10906720 10.1002/1520-6017(200008)89: 8<967::AID-JPS1>3.0.CO;2-R 1:CAS:528:DC%2BD3cXmtVWms7c%3D
-
(2000)
J Pharm Sci
, vol.89
, Issue.8
, pp. 967-978
-
-
Charman, W.N.1
-
7
-
-
34247536339
-
Morphological observations on a lipid-based drug delivery system during in vitro digestion
-
DOI 10.1016/j.ejps.2007.02.009, PII S0928098707000486
-
DG Fatouros B Bergenstahl A Mullertz 2007 Morphological observations on a lipid-based drug delivery system during in vitro digestion Eur J Pharm Sci 31 2 85 94 17418543 10.1016/j.ejps.2007.02.009 1:CAS:528:DC%2BD2sXkvFyqu7c%3D (Pubitemid 46660577)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.31
, Issue.2
, pp. 85-94
-
-
Fatouros, D.G.1
Bergenstahl, B.2
Mullertz, A.3
-
8
-
-
10044275609
-
Influence of surfactant and lipid chain length on the solubilisation of phosphatidylcholine vesicles by micelles comprised of polyoxyethylene sorbitan monoesters
-
DOI 10.1016/j.colsurfa.2004.06.042, PII S0927775704005291
-
WH Lim MJ Lawrence 2004 Influence of surfactant and lipid chain length on the solubilisation of phosphatidylcholine vesicles by micelles comprised of polyoxyethylene sorbitan monoesters Colloid Surf A 250 1-3 449 457 10.1016/j.colsurfa.2004.06.042 1:CAS:528:DC%2BD2cXhtVKlurfN (Pubitemid 39610822)
-
(2004)
Colloids and Surfaces A: Physicochemical and Engineering Aspects
, vol.250
, Issue.1-3 SPEC. ISS.
, pp. 449-457
-
-
Lim, W.H.1
Lawrence, M.J.2
-
9
-
-
2042505686
-
Aggregation behaviour of mixtures of phosphatidylcholine and polyoxyethylene sorbitan monoesters in aqueous solution
-
10.1039/b314610n 1:CAS:528:DC%2BD2cXisVers74%3D
-
WH Lim MJ Lawrence 2004 Aggregation behaviour of mixtures of phosphatidylcholine and polyoxyethylene sorbitan monoesters in aqueous solution Phys Chem Chem Phys 6 7 1380 1387 10.1039/b314610n 1:CAS:528: DC%2BD2cXisVers74%3D
-
(2004)
Phys Chem Chem Phys
, vol.6
, Issue.7
, pp. 1380-1387
-
-
Lim, W.H.1
Lawrence, M.J.2
-
10
-
-
21344438401
-
Enzymatic characterization of lipid-based drug delivery systems
-
DOI 10.1016/j.ijpharm.2005.02.038, PII S0378517305002413, Selected Contribution from the 5th European Workshop on Particulate Systems
-
H Ljusberg-Wahren F Seier Nielsen M Brogard E Troedsson A Mullertz 2005 Enzymatic characterization of lipid-based drug delivery systems Int J Pharm 298 2 328 332 15979260 10.1016/j.ijpharm.2005.02.038 1:CAS:528:DC%2BD2MXlvV2nu78%3D (Pubitemid 40910737)
-
(2005)
International Journal of Pharmaceutics
, vol.298
, Issue.2
, pp. 328-332
-
-
Ljusberg-Wahren, H.1
Nielsen, F.S.2
Brogard, M.3
Troedsson, E.4
Mullertz, A.5
-
11
-
-
78650679656
-
Factors affecting lipase digestibility of emulsified lipids using an in vitro digestion model: Proposal for a standardised pH-stat method
-
10.1016/j.foodchem.2010.11.027 1:CAS:528:DC%2BC3cXhs1SrurvP
-
Y Li M Hu DJ McClements 2011 Factors affecting lipase digestibility of emulsified lipids using an in vitro digestion model: proposal for a standardised pH-stat method Food Chem 126 2 498 505 10.1016/j.foodchem.2010.11.027 1:CAS:528:DC%2BC3cXhs1SrurvP
-
(2011)
Food Chem
, vol.126
, Issue.2
, pp. 498-505
-
-
Li, Y.1
Hu, M.2
McClements, D.J.3
-
12
-
-
33751014029
-
Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system
-
DOI 10.1016/j.ejps.2006.04.016, PII S0928098706001151
-
CW Pouton 2006 Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system Eur J Pharm Sci 29 3-4 278 287 16815001 10.1016/j.ejps.2006.04.016 1:CAS:528:DC%2BD28XhtFentrrM (Pubitemid 44740131)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.29
, Issue.3-4 SPEC. ISS.
, pp. 278-287
-
-
Pouton, C.W.1
-
13
-
-
70349238697
-
Design of lipid-based formulations for oral administration of poorly water-soluble drugs: Precipitation of drug after dispersion of formulations in aqueous solution
-
19130605 10.1002/jps.21659 1:CAS:528:DC%2BD1MXhtVKhsr7K
-
K Mohsin MA Long CW Pouton 2009 Design of lipid-based formulations for oral administration of poorly water-soluble drugs: precipitation of drug after dispersion of formulations in aqueous solution J Pharm Sci 98 10 3582 3595 19130605 10.1002/jps.21659 1:CAS:528:DC%2BD1MXhtVKhsr7K
-
(2009)
J Pharm Sci
, vol.98
, Issue.10
, pp. 3582-3595
-
-
Mohsin, K.1
Long, M.A.2
Pouton, C.W.3
-
14
-
-
0028081549
-
Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides
-
DOI 10.1023/A:1018927402875
-
PP Constantinides J-P Scalart C Lancaster J Marcello G Marks H Ellens, et al. 1994 Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides Pharmaceut Res 11 10 1385 1390 10.1023/A:1018927402875 1:CAS:528:DyaK2MXivFaltLk%3D (Pubitemid 24339642)
-
(1994)
Pharmaceutical Research
, vol.11
, Issue.10
, pp. 1385-1390
-
-
Constantinides, P.P.1
Scalart, J.-P.2
Lancaster, C.3
Marcello, J.4
Marks, G.5
Ellens, H.6
Smith, P.L.7
-
15
-
-
0034601204
-
Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs
-
DOI 10.1016/S0939-6411(00)00089-8, PII S0939641100000898
-
T Gershanik S Benita 2000 Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs Eur J Pharm Biopharm 50 1 179 188 10840200 10.1016/S0939-6411(00)00089-8 1:CAS:528:DC%2BD3cXjslyisrk%3D (Pubitemid 30326696)
-
(2000)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.50
, Issue.1
, pp. 179-188
-
-
Gershanik, T.1
Benita, S.2
-
16
-
-
33847260132
-
A new standardized lipolysis approach for characterization of emulsions and dispersions
-
17289070 10.1016/j.jcis.2006.12.015 1:CAS:528:DC%2BD2sXitlGgu7c%3D
-
M Brogard E Troedsson K Thuresson H Ljusberg-Wahren 2007 A new standardized lipolysis approach for characterization of emulsions and dispersions J Colloid Interface Sci 308 2 500 507 17289070 10.1016/j.jcis.2006. 12.015 1:CAS:528:DC%2BD2sXitlGgu7c%3D
-
(2007)
J Colloid Interface Sci
, vol.308
, Issue.2
, pp. 500-507
-
-
Brogard, M.1
Troedsson, E.2
Thuresson, K.3
Ljusberg-Wahren, H.4
-
17
-
-
39149091886
-
Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs
-
DOI 10.1002/jps.21246
-
JF Cuine CL McEvoy WN Charman CW Pouton GA Edwards H Benameur, et al. 2008 Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs J Pharm Sci 97 2 993 1010 10.1002/jps.21246 (Pubitemid 351293898)
-
(2008)
Journal of Pharmaceutical Sciences
, vol.97
, Issue.2
, pp. 995-1012
-
-
Cuine, J.F.1
Mcevoy, C.L.2
Charman, W.N.3
Pouton, C.W.4
Edwards, G.A.5
Benameur, H.6
Porter, C.J.H.7
-
18
-
-
80052265520
-
In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems
-
21392564 10.1016/j.ijpharm.2011.03.002 1:CAS:528:DC%2BC3MXhtVygsL%2FF
-
AT Larsen P Sassene A Mullertz 2011 In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems Int J Pharm 417 1-2 245 255 21392564 10.1016/j.ijpharm.2011.03.002 1:CAS:528:DC%2BC3MXhtVygsL%2FF
-
(2011)
Int J Pharm
, vol.417
, Issue.12
, pp. 245-255
-
-
Larsen, A.T.1
Sassene, P.2
Mullertz, A.3
-
19
-
-
0024674201
-
The role of calcium ions and bile salts on the pancreatic lipase-catalyzed hydrolysis of triglyceride emulsions stabilized with lecithin
-
2762220 10.1023/A:1015956104500 1:CAS:528:DyaL1MXkvVeqtLc%3D
-
FJ Alvarez VJ Stella 1989 The role of calcium ions and bile salts on the pancreatic lipase-catalyzed hydrolysis of triglyceride emulsions stabilized with lecithin Pharm Res 6 6 449 457 2762220 10.1023/A:1015956104500 1:CAS:528:DyaL1MXkvVeqtLc%3D
-
(1989)
Pharm Res
, vol.6
, Issue.6
, pp. 449-457
-
-
Alvarez, F.J.1
Stella, V.J.2
-
20
-
-
0343051926
-
Influence of lipolysis on drug absorption from the gastro-intestinal tract
-
DOI 10.1016/S0169-409X(96)00489-9, PII S0169409X96004899
-
KJ MacGregor JK Embleton JE Lacy EA Perry LJ Solomon H Seager, et al. 1997 Influence of lipolysis on drug absorption from the gastro-intestinal tract Adv Drug Deliver Rev 25 1 33 46 10.1016/S0169-409X(96)00489-9 1:CAS:528:DyaK2sXhtlOqsrY%3D (Pubitemid 27107789)
-
(1997)
Advanced Drug Delivery Reviews
, vol.25
, Issue.1
, pp. 33-46
-
-
MacGregor, K.J.1
Embleton, J.K.2
Lacy, J.E.3
Perry, E.A.4
Solomon, L.J.5
Seager, H.6
Pouton, C.W.7
-
21
-
-
0035016152
-
Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis
-
DOI 10.1016/S0731-7085(00)00528-8, PII S0731708500005288
-
L Sek CJ Porter WN Charman 2001 Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis J Pharm Biomed Anal 25 3-4 651 661 11377046 10.1016/S0731-7085(00)00528-8 1:CAS:528:DC%2BD3MXjslelurw%3D (Pubitemid 32493922)
-
(2001)
Journal of Pharmaceutical and Biomedical Analysis
, vol.25
, Issue.3-4
, pp. 651-661
-
-
Sek, L.1
Porter, C.J.H.2
Charman, W.N.3
-
22
-
-
0036159895
-
Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products
-
DOI 10.1211/0022357021771896
-
L Sek CJ Porter AM Kaukonen WN Charman 2002 Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products J Pharm Pharmacol 54 1 29 41 11833493 10.1211/0022357021771896 1:CAS:528:DC%2BD38XhtlWru78%3D (Pubitemid 34116220)
-
(2002)
Journal of Pharmacy and Pharmacology
, vol.54
, Issue.1
, pp. 29-41
-
-
Sek, L.1
Porter, C.J.H.2
Kaukonen, A.M.3
Charman, W.N.4
-
23
-
-
33746766894
-
Simplified spectrophotometric method using methylene blue for determining anionic surfactants: Applications to the study of primary biodegradation in aerobic screening tests
-
DOI 10.1016/j.chemosphere.2006.02.044, PII S0045653506002360
-
E Jurado M Fernandez-Serrano J Nunez-Olea G Luzon M Lechuga 2006 Simplified spectrophotometric method using methylene blue for determining anionic surfactants: applications to the study of primary biodegradation in aerobic screening tests Chemosphere 65 2 278 285 16616296 10.1016/j.chemosphere. 2006.02.044 1:CAS:528:DC%2BD28Xot1Wqt74%3D (Pubitemid 44163357)
-
(2006)
Chemosphere
, vol.65
, Issue.2
, pp. 278-285
-
-
Jurado, E.1
Fernandez-Serrano, M.2
Nunez-Olea, J.3
Luzon, G.4
Lechuga, M.5
-
24
-
-
33847364354
-
Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs
-
DOI 10.1007/s11095-006-9194-z
-
JF Cuine WN Charman CW Pouton GA Edwards CJ Porter 2007 Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs Pharm Res 24 4 748 757 17372700 10.1007/s11095-006-9194-z 1:CAS:528:DC%2BD2sXivVSgsro%3D (Pubitemid 46411963)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.4
, pp. 748-757
-
-
Cuine, J.F.1
Charman, W.N.2
Pouton, C.W.3
Edwards, G.A.4
Porter, C.J.H.5
-
25
-
-
0035991618
-
Examination of the solubilization of drugs by bile salt micelles
-
DOI 10.1002/jps.10158
-
TS Wiedmann L Kamel 2002 Examination of the solubilization of drugs by bile salt micelles J Pharm Sci 91 8 1743 1764 12115803 10.1002/jps.10158 1:CAS:528:DC%2BD38XlvV2ks74%3D (Pubitemid 34810521)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.8
, pp. 1743-1764
-
-
Wiedmann, T.S.1
Kamel, L.2
-
26
-
-
33750592309
-
Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: Correlation with in vivo data and the relationship to intra-enterocyte processes in rats
-
16902814 10.1007/s11095-006-9054-x 1:CAS:528:DC%2BD28XptVaitro%3D
-
A Dahan A Hoffman 2006 Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: correlation with in vivo data and the relationship to intra-enterocyte processes in rats Pharm Res 23 9 2165 2174 16902814 10.1007/s11095-006-9054-x 1:CAS:528:DC%2BD28XptVaitro%3D
-
(2006)
Pharm Res
, vol.23
, Issue.9
, pp. 2165-2174
-
-
Dahan, A.1
Hoffman, A.2
-
27
-
-
5644294406
-
Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols
-
DOI 10.1016/j.ejps.2004.08.003, PII S0928098704002003
-
JO Christensen K Schultz B Mollgaard HG Kristensen A Mullertz 2004 Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols Eur J Pharm Sci 23 3 287 296 15489130 10.1016/j.ejps.2004.08.003 1:CAS:528:DC%2BD2cXos1ersbw%3D (Pubitemid 39369884)
-
(2004)
European Journal of Pharmaceutical Sciences
, vol.23
, Issue.3
, pp. 287-296
-
-
Christensen, J.O.1
Schultz, K.2
Mollgaard, B.3
Kristensen, H.G.4
Mullertz, A.5
-
28
-
-
0343487750
-
Formulation of self-emulsifying drug delivery systems
-
DOI 10.1016/S0169-409X(96)00490-5, PII S0169409X96004905
-
CW Pouton 1997 Formulation of self-emulsifying drug delivery systems Adv Drug Deliver Rev 25 1 47 58 10.1016/S0169-409X(96)00490-5 1:CAS:528: DyaK2sXhtlOqsrc%3D (Pubitemid 27107790)
-
(1997)
Advanced Drug Delivery Reviews
, vol.25
, Issue.1
, pp. 47-58
-
-
Pouton, C.W.1
-
29
-
-
0036922497
-
Fenofibrate in the treatment of dyslipidemia: A review of the data as they relate to the new suprabioavailable tablet formulation
-
DOI 10.1016/S0149-2918(02)80095-9
-
J Najib 2002 Fenofibrate in the treatment of dyslipidemia: a review of the data as they relate to the new suprabioavailable tablet formulation Clin Ther 24 12 2022 2050 12581543 10.1016/S0149-2918(02)80095-9 1:CAS:528: DC%2BD3sXps1Gltg%3D%3D (Pubitemid 36051529)
-
(2002)
Clinical Therapeutics
, vol.24
, Issue.12
, pp. 2022-2050
-
-
Najib, J.1
-
30
-
-
0342617694
-
Lipid based vehicles for the oral delivery of poorly water soluble drugs
-
10.1016/S0169-409X(96)00494-2 1:CAS:528:DyaK2sXhtlOqs70%3D
-
AJ Humberstone WN Charman 1997 Lipid based vehicles for the oral delivery of poorly water soluble drugs Adv Drug Deliv Rev 25 1 103 128 10.1016/S0169-409X(96)00494-2 1:CAS:528:DyaK2sXhtlOqs70%3D
-
(1997)
Adv Drug Deliv Rev
, vol.25
, Issue.1
, pp. 103-128
-
-
Humberstone, A.J.1
Charman, W.N.2
-
31
-
-
0029997106
-
Fatty acid transfer in taurodeoxycholate mixed micelles
-
DOI 10.1021/bi952979k
-
VS Narayanan J Storch 1996 Fatty acid transfer in taurodeoxycholate mixed micelles Biochemistry 35 23 7466 7473 8652524 10.1021/bi952979k 1:CAS:528:DyaK28XjtVCiu7k%3D (Pubitemid 26189812)
-
(1996)
Biochemistry
, vol.35
, Issue.23
, pp. 7466-7473
-
-
Narayanan, V.S.1
Storch, J.2
|