Self-emulsifying pellets in a lab-scale high shear mixer: Formulation and production design

Powder Technology

Volumn 207, Issue 1-3, 2011, Pages 113-118

  Franceschinis, E ^a   Bortoletto, C ^a   Perissutti, B ^b   Dal Zotto, M ^a   Voinovich, D ^b   Realdon, N ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

High shear wet granulation; Piroxicam; Process optimization; Self emulsifying drug delivery system

Indexed keywords

DISSOLUTION RATES; DROPLET SIZES; DRUG DISSOLUTION; EXPERIMENTAL CONDITIONS; HIGH SHEAR MIXERS; HIGH-SHEAR WET GRANULATION; IMPELLER SPEED; OIL-IN-WATER MICROEMULSIONS; OPERATING CONDITION; PELLET PRODUCTION; PELLET SIZE; PHYSICOCHEMICAL PROPERTY; PIROXICAM; PROCESS OPTIMIZATION; PRODUCTION DESIGNS; SELF-EMULSIFYING DRUG DELIVERY SYSTEM; SOLUBLE MODELS; TECHNOLOGICAL PROPERTIES; WET GRANULATION;

DISSOLUTION; DRUG DELIVERY; DRUG PRODUCTS; GRANULATION; MICROEMULSIONS; MIXERS (MACHINERY); OPTIMIZATION; ORE PELLETS; PELLETIZING; PHASE DIAGRAMS; PROCESS CONTROL; PYRIDINE;

EMULSIFICATION;

DRUG VEHICLE; OIL; PIROXICAM; WATER;

ARTICLE; CHEMICAL COMPOSITION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG GRANULATION; DRUG SOLUBILITY; DRUG STABILITY; EMULSION; LOADING DRUG DOSE; PARTICLE SIZE; PHYSICAL CHEMISTRY; SELF EMULSIFYING DRUG DELIVERY SYSTEM; SOLID STATE; VISCOSITY;

EID: 78751577773     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.10.016     Document Type: Article

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