Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma

DMM Disease Models and Mechanisms

Volumn 8, Issue 5, 2015, Pages 443-455

  Bosco, Alejandra ^a   Romero, Cesar O ^a   Breen, Kevin T ^a   Chagovetz, Alexis A ^a   Steele, Michael R ^a   Ambati, Balamurali K ^a   Vetter, Monica L ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Confocal ophthalmoscopy; Cx3cr1GFP + DBA 2J; Live image analysis; Microglia activation; Microgliosis; Retinal ganglion cells

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; MINOCYCLINE; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE;

AGING; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATTENUATION; CELL DENSITY; CONFOCAL SCANNING LASER OPHTHALMOSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; GLAUCOMA; GLIOSIS; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROPATHY; NONHUMAN; OPTIC NERVE; OPTIC NERVE DEGENERATION; OPTIC NERVE DISEASE; OPTIC NERVE HEAD; PATHOGENESIS; PRIORITY JOURNAL; RETINA; RETINA GANGLION CELL; SCANNING LASER OPHTHALMOSCOPY; ANIMAL; C57BL MOUSE; DBA MOUSE; DISEASE MODEL; FEMALE; LASER; MALE; METABOLISM; OPHTHALMOSCOPY; OPTIC DISK; PATHOLOGY;

ANIMALIA;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; GLIOSIS; LASERS; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; MICROGLIA; NERVE DEGENERATION; OPHTHALMOSCOPY; OPTIC DISK; RECEPTORS, CHEMOKINE; RETINA;

EID: 84928985478     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.018788     Document Type: Article

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