Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma

Archives of Ophthalmology

Volumn 117, Issue 8, 1999, Pages 1050-1056

  Neufeld, Arthur H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; HLA DR ANTIGEN;

ADULT; AGED; ARTICLE; BLOOD RETINA BARRIER; CHORIORETINOPATHY; CONTROLLED STUDY; GLAUCOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROGLIA; OPTIC DISK; OPTIC NERVE ATROPHY; PRIORITY JOURNAL; STELLATE CELL;

EID: 0032809910     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.117.8.1050     Document Type: Article

References (25)

1. Grayson MC, Laties AM. Ocular localization of sodium fluorescein: effects of administration in rabbit and monkey. Arch Ophthalmol. 1971;85:600-603.
2. Tso MO, Shih CY, McLean IW. Is there a blood-brain barrier at the optic nerve head? Arch Ophthalmol. 1975;93:815-825.
3. Cohen AI. Is there a potential defect in the blood-retinal barrier at the choroidal level of the optic nerve canal? Invest Ophthalmol. 1973;12:513-519.
4. Motolko M, Drance SM. Features of the optic disc in preglaucomatous eyes. Arch Ophthalmol. 1981;99:1992-1994.
5. Wilensky JT, Kolker AE. Peripapillary changes in glaucoma. Am J Ophthalmol. 1976;81:341-345.
6. Fantes FE, Anderson DR. Clinical histologic correlation of human peripapillary anatomy. Ophthalmology. 1989;96:20-25.
7. Hayreh SS. Blood supply of the optic nerve head and its role in optic atrophy, glaucoma, and oedema of the optic disc. Br J Ophthalmol. 1969;53:721-748.
8. Kubota T, Jonas JB, Naumann GO. Direct clinico-histological correlation of parapapillary chorioretinal atrophy. Br J Ophthalmol. 1993;77:103-106.
9. Jonas JB, Nguyen XN, Gusek GC, Naumann GO. Parapapillary chorioretinal atrophy in normal and glaucoma eyes, I: morphometric data. Invest Ophthalmol Vis Sci. 1989;30:908-918.
10. Jonas JB, Naumann GO. Parapapillary chorioretinal atrophy in normal and glaucoma eyes, II: correlations. Invest Ophthalmol Vis Sci. 1989;30:919-926.
11. Jonas JB, Grundler AE, Gonzales-Cortes J. Pressure-dependent neuroretinal rim loss in normal-pressure glaucoma. Am J Ophthalmol. 1998;125:137-144.
12. Jonas JB, Grundler A. Optic disc morphology in "age-related atrophic glaucoma." Graefes Arch Clin Exp Ophthalmol. 1996;234:744-749.
13. Geijssen HC, Greve EL. The spectrum of primary open angle glaucoma, I: senile sclerotic glaucoma versus high-tension glaucoma. Ophthalmic Surg. 1987;18:207-213.
14. Nicolela MT, Drance SM. Various glaucomatous optic nerve appearances: clinical correlations. Ophthalmology. 1996;103:640-649.
15. Tezel G, Kolker AE, Kass MA, Wax MB, Gordon M, Siegmund KD. Parapapillary chorioretinal atrophy in patients with ocular hypertension, I: an evaluation as a predictive factor for the development of glaucomatous damage. Arch Ophthalmol. 1997;115:1503-1508.
16. Tezel G, Kolker AE, Wax MB, Kass MA, Gordon M, Siegmund KD. Parapapillary chorioretinal atrophy in patients with ocular hypertension, II: an evaluation of progressive changes. Arch Ophthalmol. 1997;115:1509-1514.
17. Anderson DR. The mechanisms of damage of the optic nerve. In: Kriegelstein GK, Leydhecker W, eds. Glaucoma Update II. Berlin, Germany: Springer-Verlag; 1983:89-93.
18. Neufeld AH, Hernandez MR, Gonzalez M. Nitric oxide synthase in the human glaucomatous optic nerve head. Arch Ophthalmol. 1997;115:497-503.
19. Perry VH, Andersson PB, Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 1993;16:268-273.
20. Perry VH, Gordon S. Macrophages and microglia in the nervous system. Trends Neurosci. 1988;11:273-277.
21. Provis JM, Penfold PL, Edwards AJ, van Driel D. Human retinal microglia: expression of immune markers and relationship to the glia limitans. Glia. 1995;14: 243-256.
22. Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996;19:312-318.
23. Banati RB, Graeber MB. Surveillance, intervention and cytotoxicity: is there a protective role of microglia? Dev Neurosci. 1994;16:114-127.
24. Ling EA, Wong WC. The origin and nature of ramified and amoeboid microglia: a historical review and current concepts. Glia. 1993;7:9-18.
25. Gehrmann J, Banati RB, Kreutzberg GW. Microglia in the immune surveillance of the brain: human microglia constitutively express HLA-DR molecules. J Neuroimmunol. 1993;48:189-198.