Longitudinal profile of retinal ganglion cell damage after optic nerve crush with blue-light confocal scanning laser ophthalmoscopy

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 11, 2008, Pages 4898-4902

  Leung, Christopher Kai Shun ^a,b   Lindsey, James D ^a   Crowston, Jonathan G ^c   Lijia, Chen ^b   Chiang, Sylvia ^b   Weinreb, Robert N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANIMAL EXPERIMENT; ARTICLE; BLUE LIGHT; CELL DAMAGE; CELL DENSITY; CONTROLLED STUDY; EXCITATION; FLUORESCENCE; IN VIVO STUDY; MOUSE; NERVE CRUSH; NONHUMAN; OPHTHALMOSCOPE; OPTIC NERVE; PRIORITY JOURNAL; RETINA BLOOD VESSEL; RETINA DEGENERATION; RETINA GANGLION CELL; SCANNING LASER OPHTHALMOSCOPY; SHAM PROCEDURE; ANIMAL; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; EYE FUNDUS; FLUORESCENCE ANGIOGRAPHY; FLUORESCENCE MICROSCOPY; FOLLOW UP; METHODOLOGY; OPHTHALMOSCOPY; OPTIC NERVE INJURY; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; REPRODUCIBILITY; RETINA DISEASE; TIME; TRANSGENIC MOUSE;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FLUORESCEIN ANGIOGRAPHY; FOLLOW-UP STUDIES; FUNDUS OCULI; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; OPHTHALMOSCOPY; OPTIC NERVE INJURIES; REPRODUCIBILITY OF RESULTS; RETINAL DISEASES; RETINAL GANGLION CELLS; TIME FACTORS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 56149113407     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1447     Document Type: Article

References (17)

1. Leung CK, Lindsey JD, Crowston JG, et al. In vivo imaging of murine retinal ganglion cells. J Neurosci Methods. 2008;168:475-478.
2. Morris R. Thy-1 in developing nervous tissue. Dev Neurosci. 1985;7:133-160.
3. Barnstable CJ, Drager UC. Thy-1 antigen: a ganglion cell specific marker in rodent retina. Neuroscience. 1984;11:847-855.
4. Huang W, Fileta J, Guo Y, et al. Downregulation of Thy1 in retinal ganglion cells in experimental glaucoma. Curr Eye Res. 2006;31:265-271. (Pubitemid 43379197)
5. Schlamp CL, Johnson EC, Li Y, et al. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Mol Vis. 2001;7:192-201. (Pubitemid 36153670)
6. Chidlow G, Casson R, Sobrado-Calvo P, et al. Measurement of retinal injury in the rat after optic nerve transection: an RT-PCR study. Mol Vis. 2005;11:387-396. (Pubitemid 41358268)
7. Nash MS, Osborne NN. Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage. Invest Ophthalmol Vis Sci. 1999;40:1293-1298.
8. Feng G, Mellor RH, Bernstein M, et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 2000;28:41-51.
9. Li Y, Schlamp CL, Nickells RW. Experimental induction of retinal ganglion cell death in adult mice. Invest Ophthalmol Vis Sci. 1999;40:1004-1008. (Pubitemid 29153269)
10. Cordeiro MF, Guo L, Luong V, et al. Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration. Proc Natl Acad Sci U S A. 2004;101:13352-13356. (Pubitemid 39209669)
11. Higashide T, Kawaguchi I, Ohkubo S, et al. In vivo imaging and counting of rat retinal ganglion cells using a scanning laser ophthalmoscope. Invest Ophthalmol Vis Sci. 2006;47:2943-2950. (Pubitemid 351639770)
12. Hollander H, Bisti S, Maffei L. Long term survival of cat retinal ganglion cells after intracranial optic nerve transection. Exp Brain Res. 1985;59:633-635. (Pubitemid 15042264)
13. Fang D, Kerppola TK. Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes. Proc Natl Acad Sci U S A. 2004;101:14782-14787. (Pubitemid 39410752)
14. Belkhiri A, Lytvyn V, Guilbault C, et al. A noninvasive cell-based assay for monitoring proteolytic activity within a specific subcellular compartment. Anal Biochem. 2002;306:237-246. (Pubitemid 34791492)
15. Ahmed F, Brown KM, Stephan DA, Morrison JC, Johnson EC, Tomarev SI. Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure. Invest Ophthalmol Vis Sci. 2004;45:1247-1258. (Pubitemid 38869033)
16. Yoles E, Schwartz M. Degeneration of spared axons following partial white matter lesion: implications for optic nerve neuropathies. Exp Neurol. 1998;153:1-7. (Pubitemid 28452292)
17. Levkovitch-Verbin H, Quigley HA, Kerrigan-Baumrind LA, et al. Optic nerve transection in monkeys may result in secondary degeneration of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2001;42:975-982. (Pubitemid 32289792)