Protein maturation and proteolysis in plant plastids, mitochondria, and peroxisomes

Annual Review of Plant Biology

Volumn 66, Issue , 2015, Pages 75-111

  Van Wijk, Klaas J ^a  

^a Cornell University ^*  (United States)

Author keywords

Autophagy; Degradomics; Degron; Endosymbiotic organelle; Proteome remodeling; Proteostasis

Indexed keywords

EUKARYOTA;

VEGETABLE PROTEIN;

CHLOROPLAST; METABOLISM; MITOCHONDRION; PEROXISOME; PLANT; PLASTID; PROTEIN DEGRADATION;

CHLOROPLASTS; MITOCHONDRIA; PEROXISOMES; PLANT PROTEINS; PLANTS; PLASTIDS; PROTEOLYSIS;

EID: 84928895757     PISSN: 15435008     EISSN: 15452123     Source Type: Book Series    
DOI: 10.1146/annurev-arplant-043014-115547     Document Type: Article

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2. DEG14 (located in themitochondria) and FTSH11 (located in mitochondria and chloroplasts) confer thermotolerance in Arabidopsis, likely by degrading misfolded proteins. No other organellar proteases are (yet) known to confer thermotolerance.
3. Different protease systems have developed unique ways to prevent unwanted proteolysis. These occur through the sequestration of active sites within oligomeric structures, selective activation by changes in oligomeric state, and specific substrate delivery systems and adaptors that direct substrates to the proteolytic sites.
4. There is a fascinating interplay between intraorganellar proteolysis, the proteasome, and autophagy. These three processes are known to act in a complementary fashion, but much remains to be discovered about their functions and interactions.
5. Organellar proteolysis and autophagy have been studiedmainly in Arabidopsis, but several recent studies have illustrated the importance of organellar proteases and autophagy in crop plants. These findings could potentially have a large impact on agriculture.
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