Novel highly sensitive, specific, and straightforward strategy for comprehensive N-terminal proteomics reveals unknown substrates of the mitochondrial peptidase Icp55

Journal of Proteome Research

Volumn 12, Issue 9, 2013, Pages 3823-3830

  Venne, A Saskia ^a   Vögtle, F Nora ^b   Meisinger, Chris ^b,c   Sickmann, Albert ^a,d   Zahedi, René P ^a  

^a LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^b ZBMZ   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

COFRADIC; degradomics; Icp55; N terminal; peptidase; protease

Indexed keywords

AMINO ACID; MITOCHONDRIAL PROTEIN; PEPTIDASE; PROTEIN PRECURSOR; PROTEINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CHARGE BASED FRACTIONAL DIAGONAL CHROMATOGRAPHY; CONTROLLED STUDY; ION EXCHANGE CHROMATOGRAPHY; LIMIT OF QUANTITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEOMICS; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; PROTEOME; PROTEOMICS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, PROTEIN; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84883792762     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400435d     Document Type: Article

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