Predicting human genetic interactions from cancer genome evolution

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Lu, Xiaowen ^a   Megchelenbrink, Wout ^a,b   Notebaart, Richard A ^a   Huynen, Martijn A ^c  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; AREA UNDER THE CURVE; ARTICLE; BIOTECHNOLOGY; CANCER CELL; CANCER GENOME; CLASSIFIER; COMPUTER PREDICTION; CONTROLLED STUDY; COPY NUMBER VARIATION; DOWN REGULATION; ENSEMBLE BASED MODEL; FALSE POSITIVE RESULT; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE LOSS; GENE MAPPING; GENE OVEREXPRESSION; GENETIC DATABASE; GENETIC VARIABILITY; GENOME; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MEDICAL GENETICS; MOLECULAR EVOLUTION; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; SINGLE NUCLEOTIDE POLYMORPHISM; SYNTHETIC LETHAL GENETIC INTERACTION; UPREGULATION; VALIDATION PROCESS; BIOLOGICAL MODEL; EPISTASIS; GENETICS; HUMAN GENOME; NEOPLASM;

DNA COPY NUMBER VARIATIONS; EPISTASIS, GENETIC; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; MODELS, GENETIC; NEOPLASMS; ROC CURVE;

EID: 84928678841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125795     Document Type: Article

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