Genome-wide prediction of C. elegans genetic interactions

Science

Volumn 311, Issue 5766, 2006, Pages 1481-1484

  Zhong, Weiwei ^a   Sternberg, Paul W ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES;

GENE EXPRESSION; GENETIC INTERACTION NETWORK; HUMAN DISEASE-RELATED GENES;

GENETIC ENGINEERING;

GENOME;

ARTICLE; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; GENE CLUSTER; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENOME ANALYSIS; METAZOON; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ALGORITHMS; ANIMALS; CAENORHABDITIS ELEGANS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DROSOPHILA MELANOGASTER; GENOME, HELMINTH; HUMANS; SACCHAROMYCES CEREVISIAE;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; METAZOA; SACCHAROMYCES CEREVISIAE;

EID: 33644864549     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1123287     Document Type: Article

References (22)

1. E. M. Marcotte, M. Pellegrini, M. J. Thompson, T. O. Yeates, D. Eisenberg, Nature 402, 83 (1999).
2. O. G. Troyanskaya, K. Dolinski, A. B. Owen, R. B. Altman, D. Botstein, Proc. Natl. Acad. Sci. U.S.A. 100, 8348 (2003).
3. R. Jansen et al., Science 302, 449 (2003).
4. I. Lee, S. V. Date, A. T. Adai, E. M. Marcotte, Science 306, 1555 (2004).
5. S. L. Wong et al., Proc. Natl. Acad. Sci. U.S.A 101, 15682 (2004).
6. D. R. Rhodes et al., Nat. Biotechnol. 23, 951 (2005).
7. S. J. Boulton et al., Science 295, 127 (2002).
8. K. C. Gunsalus et al., Nature 436, 861 (2005).
9. See supporting material on Science Online.
10. M. Ashburner et al., Nat. Genet. 25, 25 (2000).
11. E. M. Schwarz et al., Nucleic Acids Res. 34, D475 (2006).
12. S. Li et al., Science 303, 540 (2004); published online 2 January 2004 (10.1126/science.1091403).
13. K. P. O'Brien, M. Remm, E. L. Sonnhammer, Nucleic Acids Res. 33, D476 (2005).
14. A. Baudot et al., Bioinformatics 22, 248 (2006).
15. G. J. Beitel, S. G. Clark, H. R. Horvitz, Nature 348, S03 (1990).
16. K. Iwasaki, O. W. Liu, J. H. Thomas, Proc. Natl. Acad. Sci. U.S.A 92, 10317 (1995).
17. D. S. Walker, N. J. Gower, S. Ly, G. L. Bradley, H. A. Baylis, Mol. Biol. Cell 13, 1329 (2002).
18. J. Lee et al., J. Mol. Biol. 344, 585 (2004).
19. N. Moghai, L. R. Garcia, L. A. Khan, K. Iwasaki, P. W. Sternberg, Development 130, 4553 (2003).
20. Y. Wu, M. Han, Genes Dev. 8, 147 (1994).
21. T. R. Clandinin, J. A. DeModena, P. W. Sternberg, Cell 92, S23 (1998).
22. We thank the Caenarhabditis Genetics Center for strains; WormBase staff for discussions; L. Chen for advice on statistical analysis; B. Perry for maintaining reagents; and C. Van Buskirk, E. Hallem, B. Hwang, M. Kato, E. Kipreos, R. Kishore, A. Petcherski, and E. Schwarz for critical reading of the manuscript. P.W.S. is an investigator and W.Z. is an associate of the Howard Hughes Medical Institute.