A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

Nature Genetics

Volumn 43, Issue 7, 2011, Pages 639-647

  Fedeles, Sorin V ^a   Tian, Xin ^a   Gallagher, Anna Rachel ^a   Mitobe, Michihiro ^a   Nishio, Saori ^a   Lee, Seung Hun ^a   Cai, Yiqiang ^a   Geng, Lin ^a   Crews, Craig M ^a   Somlo, Stefan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; POLYCYSTIN 1; POLYCYSTIN 2;

CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; GENE; GENE EXPRESSION; GENE INTERACTION; GENE MUTATION; KIDNEY CYST; KIDNEY POLYCYSTIC DISEASE; LIVER POLYCYSTIC DISEASE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PRKCSH GENE; SEC63 GENE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CYSTS; FEMALE; GLUCOSIDASES; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; POLYCYSTIC KIDNEY DISEASES; RECEPTORS, CELL SURFACE; TRPP CATION CHANNELS;

MUS;

EID: 79959725455     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.860     Document Type: Conference Paper

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