The pathogenic human Torsin A in Drosophila activates the unfolded protein response and increases susceptibility to oxidative stress

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Kim, A Young ^a   Seo, Jong Bok ^b   Kim, Won tae ^c   Choi, Hee Jeong ^a   Kim, Soo Young ^b   Morrow, Genevieve ^d   Tanguay, Robert M ^d   Steller, Hermann ^e   Koh, Young Ho ^a  

^a Hallym University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c National Institute of Animal Science   (South Korea)

^d UNIVERSITÉ LAVAL   (Canada)

^e ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Bip; DYT1 dystonia; HSC3; HSP22; Xbp1

Indexed keywords

2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ANDROSTANE DERIVATIVE; CALRETICULIN; CHAPERONE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; GLUCOSE-REGULATED PROTEIN 170; GLYCOPROTEIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HSP22 PROTEIN, DROSOPHILA; MORPHOLINE DERIVATIVE; TOR1A PROTEIN, HUMAN; WORTMANNIN; XBP1 PROTEIN, DROSOPHILA;

ANIMAL; BRAIN; DOWN REGULATION; DROSOPHILA; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; GENETICS; HUMAN; METABOLISM; OXIDATIVE STRESS; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ANDROSTADIENES; ANIMALS; BRAIN; CALRETICULIN; CHROMONES; DNA-BINDING PROTEINS; DOWN-REGULATION; DROSOPHILA; DROSOPHILA PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPLASMIC RETICULUM STRESS; GLYCOPROTEINS; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; MORPHOLINES; OXIDATIVE STRESS; TANDEM MASS SPECTROMETRY; UNFOLDED PROTEIN RESPONSE;

EID: 84928575360     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1518-0     Document Type: Article

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