-
1
-
-
0029877297
-
A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice
-
D. Accili, C.S. Fishburn, J. Drago, H. Steiner, J.E. Lachowicz, B.H. Park, E.B. Gauda, E.J. Lee, M.H. Cool, D.R. Sibley, C.R. Gerfen, H. Westphal, and S. Fuchs A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice Proc. Natl. Acad. Sci. U. S. A. 93 1996 1945 1949
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 1945-1949
-
-
Accili, D.1
Fishburn, C.S.2
Drago, J.3
Steiner, H.4
Lachowicz, J.E.5
Park, B.H.6
Gauda, E.B.7
Lee, E.J.8
Cool, M.H.9
Sibley, D.R.10
Gerfen, C.R.11
Westphal, H.12
Fuchs, S.13
-
3
-
-
0033985293
-
Sex differences in dopamine receptors and their relevance to ADHD
-
S.L. Anderson, and M.H. Teicher Sex differences in dopamine receptors and their relevance to ADHD Neurosci. Biobehav. Rev. 24 2000 137 141
-
(2000)
Neurosci. Biobehav. Rev.
, vol.24
, pp. 137-141
-
-
Anderson, S.L.1
Teicher, M.H.2
-
4
-
-
0037072281
-
Dopamine transmission in DYT1 dystonia: A biochemical and autoradiographical study
-
S.J. Augood, Z. Hollingsworth, D.S. Albers, L. Yang, J.C. Leung, B. Muller, C. Klein, X.O. Breakefield, and D.G. Standaert Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study Neurology 59 2002 445 448
-
(2002)
Neurology
, vol.59
, pp. 445-448
-
-
Augood, S.J.1
Hollingsworth, Z.2
Albers, D.S.3
Yang, L.4
Leung, J.C.5
Muller, B.6
Klein, C.7
Breakefield, X.O.8
Standaert, D.G.9
-
5
-
-
0036764833
-
Phenotypic variability of DYT1-PTD: Does the clinical spectrum include psychogenic dystonia?
-
A.R. Bentivoglio, M. Loi, E.M. Valente, T. Ialongo, P. Tonali, and A. Albanese Phenotypic variability of DYT1-PTD: does the clinical spectrum include psychogenic dystonia? Mov. Disord. 17 2002 1058 1063
-
(2002)
Mov. Disord.
, vol.17
, pp. 1058-1063
-
-
Bentivoglio, A.R.1
Loi, M.2
Valente, E.M.3
Ialongo, T.4
Tonali, P.5
Albanese, A.6
-
6
-
-
13844270752
-
Dopamine transporter function differences between male and female CD-1 mice
-
S.D. Bhatt, and D.E. Dluzen Dopamine transporter function differences between male and female CD-1 mice Brain Res. 1035 2005 188 195
-
(2005)
Brain Res.
, vol.1035
, pp. 188-195
-
-
Bhatt, S.D.1
Dluzen, D.E.2
-
7
-
-
1942489014
-
Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors
-
D.C. Bragg, S.M. Camp, C.A. Kaufman, J.D. Wilbur, H. Boston, D.E. Schuback, P.I. Hanson, M. Sena-Esteves, and X.O. Breakefield Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors Neuroscience 125 2004 651 661
-
(2004)
Neuroscience
, vol.125
, pp. 651-661
-
-
Bragg, D.C.1
Camp, S.M.2
Kaufman, C.A.3
Wilbur, J.D.4
Boston, H.5
Schuback, D.E.6
Hanson, P.I.7
Sena-Esteves, M.8
Breakefield, X.O.9
-
8
-
-
0034624938
-
The DYT1 phenotype and guidelines for diagnostic testing
-
S.B. Bressman, C. Sabatti, D. Raymond, D. de Leon, C. Klein, P.L. Kramer, M.F. Brin, S. Fahn, X. Breakefield, L.J. Ozelius, and N.J. Risch The DYT1 phenotype and guidelines for diagnostic testing Neurology 54 2000 1746 1752
-
(2000)
Neurology
, vol.54
, pp. 1746-1752
-
-
Bressman, S.B.1
Sabatti, C.2
Raymond, D.3
De Leon, D.4
Klein, C.5
Kramer, P.L.6
Brin, M.F.7
Fahn, S.8
Breakefield, X.9
Ozelius, L.J.10
Risch, N.J.11
-
9
-
-
0037319121
-
Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins
-
G.A. Caldwell, S. Cao, E.G. Sexton, C.C. Gelwix, J.P. Bevel, and K.A. Caldwell Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins Hum. Mol. Genet. 12 2003 307 319
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 307-319
-
-
Caldwell, G.A.1
Cao, S.2
Sexton, E.G.3
Gelwix, C.C.4
Bevel, J.P.5
Caldwell, K.A.6
-
10
-
-
2942729671
-
Increased seizure susceptibility and cortical malformation in beta-catenin mutant mice
-
V.E. Campos, M. Du, and Y. Li Increased seizure susceptibility and cortical malformation in beta-catenin mutant mice Biochem. Biophys. Res. Commun. 320 2004 606 614
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 606-614
-
-
Campos, V.E.1
Du, M.2
Li, Y.3
-
11
-
-
0037165919
-
Reduced anxiety- and depression-like behaviors in Emx1 homozygous mutant mice
-
B.J. Cao, and Y. Li Reduced anxiety- and depression-like behaviors in Emx1 homozygous mutant mice Brain Res. 937 2002 32 40
-
(2002)
Brain Res.
, vol.937
, pp. 32-40
-
-
Cao, B.J.1
Li, Y.2
-
12
-
-
17644392138
-
Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans
-
S. Cao, C.C. Gelwix, K.A. Caldwell, and G.A. Caldwell Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans J. Neurosci. 25 2005 3801 3812
-
(2005)
J. Neurosci.
, vol.25
, pp. 3801-3812
-
-
Cao, S.1
Gelwix, C.C.2
Caldwell, K.A.3
Caldwell, G.A.4
-
13
-
-
0033560924
-
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
-
R.J. Carter, L.A. Lione, T. Humby, L. Mangiarini, A. Mahal, G.P. Bates, S.B. Dunnett, and A.J. Morton Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation J. Neurosci. 19 1999 3248 3257
-
(1999)
J. Neurosci.
, vol.19
, pp. 3248-3257
-
-
Carter, R.J.1
Lione, L.A.2
Humby, T.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
15
-
-
0037332313
-
Baclofen reestablishes striatal and cortical dopamine concentrations during naloxone-precipitated withdrawal
-
S.L. Diaz, A.K. Kemmling, and G.N. Balerio Baclofen reestablishes striatal and cortical dopamine concentrations during naloxone-precipitated withdrawal Neurochem. Int. 42 2003 293 298
-
(2003)
Neurochem. Int.
, vol.42
, pp. 293-298
-
-
Diaz, S.L.1
Kemmling, A.K.2
Balerio, G.N.3
-
16
-
-
0028946418
-
Daily spontaneous running alters behavioral and neurochemical indexes of nigrostriatal function
-
D.E. Dluzen, B. Liu, C.Y. Chen, and S.E. DiCarlo Daily spontaneous running alters behavioral and neurochemical indexes of nigrostriatal function J. Appl. Physiol. 78 1995 1219 1224
-
(1995)
J. Appl. Physiol.
, vol.78
, pp. 1219-1224
-
-
Dluzen, D.E.1
Liu, B.2
Chen, C.Y.3
Dicarlo, S.E.4
-
17
-
-
0030026611
-
Estrogen alters MPTP-induced neurotoxicity in female mice: Effects on striatal dopamine concentrations and release
-
D.E. Dluzen, J.L. McDermott, and B. Liu Estrogen alters MPTP-induced neurotoxicity in female mice: effects on striatal dopamine concentrations and release J. Neurochem. 66 1996 658 666
-
(1996)
J. Neurochem.
, vol.66
, pp. 658-666
-
-
Dluzen, D.E.1
McDermott, J.L.2
Liu, B.3
-
18
-
-
0034948210
-
Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/- BDNF mutant mice
-
D.E. Dluzen, X. Gao, G.M. Story, L.I. Anderson, J. Kucera, and J.M. Walro Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/- BDNF mutant mice Exp. Neurol. 170 2001 121 128
-
(2001)
Exp. Neurol.
, vol.170
, pp. 121-128
-
-
Dluzen, D.E.1
Gao, X.2
Story, G.M.3
Anderson, L.I.4
Kucera, J.5
Walro, J.M.6
-
19
-
-
0026051904
-
A new motor test sensitive to aging and dopaminergic function
-
R. Drucker-Colin, and F. Garcia-Hernandez A new motor test sensitive to aging and dopaminergic function J. Neurosci. Methods 39 1991 153 161
-
(1991)
J. Neurosci. Methods
, vol.39
, pp. 153-161
-
-
Drucker-Colin, R.1
Garcia-Hernandez, F.2
-
21
-
-
0031716770
-
Functional brain networks in DYT1 dystonia
-
D. Eidelberg, J.R. Moeller, A. Antonini, K. Kazumata, T. Nakamura, V. Dhawan, P. Spetsieris, D. deLeon, S.B. Bressman, and S. Fahn Functional brain networks in DYT1 dystonia Ann. Neurol. 44 1998 303 312
-
(1998)
Ann. Neurol.
, vol.44
, pp. 303-312
-
-
Eidelberg, D.1
Moeller, J.R.2
Antonini, A.3
Kazumata, K.4
Nakamura, T.5
Dhawan, V.6
Spetsieris, P.7
Deleon, D.8
Bressman, S.B.9
Fahn, S.10
-
22
-
-
0024551796
-
Why isn't a mouse more like a man?
-
R.P. Erickson Why isn't a mouse more like a man? Trends Genet. 5 1989 1 3
-
(1989)
Trends Genet.
, vol.5
, pp. 1-3
-
-
Erickson, R.P.1
-
23
-
-
0023675531
-
Concept and classification of dystonia
-
S. Fahn Concept and classification of dystonia Adv. Neurol. 50 1988 1 8
-
(1988)
Adv. Neurol.
, vol.50
, pp. 1-8
-
-
Fahn, S.1
-
24
-
-
0026411318
-
The genetics of idiopathic torsion dystonia
-
S. Fahn The genetics of idiopathic torsion dystonia Int. J. Neurol. 25-26 1991 70 80
-
(1991)
Int. J. Neurol.
, vol.25-26
, pp. 70-80
-
-
Fahn, S.1
-
25
-
-
0036837148
-
Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: Behavioural and histopathological characterisation
-
P. Fernagut, E. Diguet, N. Stefanova, M. Biran, G. Wenning, P. Canioni, B. Bioulac, and F. Tison Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation Neuroscience 114 2002 1005
-
(2002)
Neuroscience
, vol.114
, pp. 1005
-
-
Fernagut, P.1
Diguet, E.2
Stefanova, N.3
Biran, M.4
Wenning, G.5
Canioni, P.6
Bioulac, B.7
Tison, F.8
-
26
-
-
0037196246
-
A simple method to measure stride length as an index of nigrostriatal dysfunction in mice
-
P.O. Fernagut, E. Diguet, B. Labattu, and F. Tison A simple method to measure stride length as an index of nigrostriatal dysfunction in mice J. Neurosci. Methods 113 2002 123 130
-
(2002)
J. Neurosci. Methods
, vol.113
, pp. 123-130
-
-
Fernagut, P.O.1
Diguet, E.2
Labattu, B.3
Tison, F.4
-
27
-
-
14244257982
-
Phenotypical characterization of genetic mouse models of Parkinson disease
-
M. Le Doux Elsevier New York
-
S. Fleming, and M.F. Chesselet Phenotypical characterization of genetic mouse models of Parkinson disease M. Le Doux Animal Models of Movement Disorder 2005 Elsevier New York 183 192
-
(2005)
Animal Models of Movement Disorder
, pp. 183-192
-
-
Fleming, S.1
Chesselet, M.F.2
-
28
-
-
7044270767
-
Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein
-
S.M. Fleming, J. Salcedo, P.O. Fernagut, E. Rockenstein, E. Masliah, M.S. Levine, and M.F. Chesselet Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein J. Neurosci. 24 2004 9434 9440
-
(2004)
J. Neurosci.
, vol.24
, pp. 9434-9440
-
-
Fleming, S.M.1
Salcedo, J.2
Fernagut, P.O.3
Rockenstein, E.4
Masliah, E.5
Levine, M.S.6
Chesselet, M.F.7
-
29
-
-
0030574076
-
The dopamine-depleting effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in CD-1 mice are gender-dependent
-
T.E. Freyaldenhoven, J.L. Cadet, and S.F. Ali The dopamine-depleting effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in CD-1 mice are gender-dependent Brain Res. 735 1996 232 238
-
(1996)
Brain Res.
, vol.735
, pp. 232-238
-
-
Freyaldenhoven, T.E.1
Cadet, J.L.2
Ali, S.F.3
-
30
-
-
0034646320
-
Striatal dopamine in early-onset primary torsion dystonia with the DYT1 mutation
-
Y. Furukawa, O. Hornykiewicz, S. Fahn, and S.J. Kish Striatal dopamine in early-onset primary torsion dystonia with the DYT1 mutation Neurology 54 2000 1193 1195
-
(2000)
Neurology
, vol.54
, pp. 1193-1195
-
-
Furukawa, Y.1
Hornykiewicz, O.2
Fahn, S.3
Kish, S.J.4
-
31
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
M.S. Goldberg, S.M. Fleming, J.J. Palacino, C. Cepeda, H.A. Lam, A. Bhatnagar, E.G. Meloni, N. Wu, L.C. Ackerson, G.J. Klapstein, M. Gajendiran, B.L. Roth, M.F. Chesselet, N.T. Maidment, M.S. Levine, and J. Shen Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons J. Biol. Chem. 278 2003 43628 43635
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
32
-
-
1642290757
-
Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia
-
P. Gonzalez-Alegre, and H.L. Paulson Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia J. Neurosci. 24 2004 2593 2601
-
(2004)
J. Neurosci.
, vol.24
, pp. 2593-2601
-
-
Gonzalez-Alegre, P.1
Paulson, H.L.2
-
33
-
-
1642433201
-
Mislocalization to the nuclear envelope: An effect of the dystonia-causing torsinA mutation
-
R.E. Goodchild, and W.T. Dauer Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation Proc. Natl. Acad. Sci. U. S. A. 101 2004 847 852
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 847-852
-
-
Goodchild, R.E.1
Dauer, W.T.2
-
34
-
-
15444374750
-
+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein
-
+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein J. Cell Biol. 168 2005 855 862
-
(2005)
J. Cell Biol.
, vol.168
, pp. 855-862
-
-
Goodchild, R.E.1
Dauer, W.T.2
-
35
-
-
0034710840
-
Normal corpus callosum in Emx1 mutant mice with C57BL/6 background
-
H. Guo, J.M. Christoff, V.E. Campos, X.L. Jin, and Y. Li Normal corpus callosum in Emx1 mutant mice with C57BL/6 background Biochem. Biophys. Res. Commun. 276 2000 649 653
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.276
, pp. 649-653
-
-
Guo, H.1
Christoff, J.M.2
Campos, V.E.3
Jin, X.L.4
Li, Y.5
-
36
-
-
0037445915
-
TorsinA in PC12 cells: Localization in the endoplasmic reticulum and response to stress
-
J. Hewett, P. Ziefer, D. Bergeron, T. Naismith, H. Boston, D. Slater, J. Wilbur, D. Schuback, C. Kamm, N. Smith, S. Camp, L.J. Ozelius, V. Ramesh, P.I. Hanson, and X.O. Breakefield TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress J. Neurosci. Res. 72 2003 158 168
-
(2003)
J. Neurosci. Res.
, vol.72
, pp. 158-168
-
-
Hewett, J.1
Ziefer, P.2
Bergeron, D.3
Naismith, T.4
Boston, H.5
Slater, D.6
Wilbur, J.7
Schuback, D.8
Kamm, C.9
Smith, N.10
Camp, S.11
Ozelius, L.J.12
Ramesh, V.13
Hanson, P.I.14
Breakefield, X.O.15
-
37
-
-
2642535914
-
TorsinB-perinuclear location and association with torsinA
-
J.W. Hewett, C. Kamm, H. Boston, R. Beauchamp, T. Naismith, L. Ozelius, P.I. Hanson, X.O. Breakefield, and V. Ramesh TorsinB-perinuclear location and association with torsinA J. Neurochem. 89 2004 1186 1194
-
(2004)
J. Neurochem.
, vol.89
, pp. 1186-1194
-
-
Hewett, J.W.1
Kamm, C.2
Boston, H.3
Beauchamp, R.4
Naismith, T.5
Ozelius, L.6
Hanson, P.I.7
Breakefield, X.O.8
Ramesh, V.9
-
38
-
-
0041866516
-
The hph-1 mouse: A model for dominantly inherited GTP-cyclohydrolase deficiency
-
K. Hyland, G.R. Munk-Martin, T.L. Arnold, and L.A. Engle The hph-1 mouse: a model for dominantly inherited GTP-cyclohydrolase deficiency Ann. Neurol. 54 2003 S46 S48
-
(2003)
Ann. Neurol.
, vol.54
-
-
Hyland, K.1
Munk-Martin, G.R.2
Arnold, T.L.3
Engle, L.A.4
-
39
-
-
0023804606
-
Clinical course of idiopathic torsion dystonia among Jews in Israel
-
R. Inzelberg, E. Kahana, and A.D. Korczyn Clinical course of idiopathic torsion dystonia among Jews in Israel Adv. Neurol. 50 1988 93 100
-
(1988)
Adv. Neurol.
, vol.50
, pp. 93-100
-
-
Inzelberg, R.1
Kahana, E.2
Korczyn, A.D.3
-
40
-
-
0034696850
-
Emx1-specific expression of foreign genes using "knock-in" approach
-
X.L. Jin, H. Guo, C. Mao, N. Atkins, H. Wang, P.P. Avasthi, Y.T. Tu, and Y. Li Emx1-specific expression of foreign genes using "knock-in" approach Biochem. Biophys. Res. Commun. 270 2000 978 982
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.270
, pp. 978-982
-
-
Jin, X.L.1
Guo, H.2
Mao, C.3
Atkins, N.4
Wang, H.5
Avasthi, P.P.6
Tu, Y.T.7
Li, Y.8
-
41
-
-
0034660063
-
Dopamine-deficient mice are hypersensitive to dopamine receptor agonists
-
D.S. Kim, M.S. Szczypka, and R.D. Palmiter Dopamine-deficient mice are hypersensitive to dopamine receptor agonists J. Neurosci. 20 2000 4405 4413
-
(2000)
J. Neurosci.
, vol.20
, pp. 4405-4413
-
-
Kim, D.S.1
Szczypka, M.S.2
Palmiter, R.D.3
-
42
-
-
5744240629
-
A Drosophila model of early onset torsion dystonia suggests impairment in TGF-beta signaling
-
Y.H. Koh, K. Rehfeld, and B. Ganetzky A Drosophila model of early onset torsion dystonia suggests impairment in TGF-beta signaling Hum. Mol. Genet. 13 2004 2019 2030
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2019-2030
-
-
Koh, Y.H.1
Rehfeld, K.2
Ganetzky, B.3
-
43
-
-
0034970023
-
Cellular distribution of torsin a and torsin B in normal human brain
-
M. Konakova, D.P. Huynh, W. Yong, and S.M. Pulst Cellular distribution of torsin A and torsin B in normal human brain Arch. Neurol. 58 2001 921 927
-
(2001)
Arch. Neurol.
, vol.58
, pp. 921-927
-
-
Konakova, M.1
Huynh, D.P.2
Yong, W.3
Pulst, S.M.4
-
44
-
-
0141448740
-
TorsinA protects against oxidative stress in COS-1 and PC12 cells
-
R. Kuner, P. Teismann, A. Trutzel, J. Naim, A. Richter, N. Schmidt, O. von Ahsen, A. Bach, B. Ferger, and A. Schneider TorsinA protects against oxidative stress in COS-1 and PC12 cells Neurosci. Lett. 350 2003 153 156
-
(2003)
Neurosci. Lett.
, vol.350
, pp. 153-156
-
-
Kuner, R.1
Teismann, P.2
Trutzel, A.3
Naim, J.4
Richter, A.5
Schmidt, N.6
Von Ahsen, O.7
Bach, A.8
Ferger, B.9
Schneider, A.10
-
45
-
-
0347284276
-
TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice
-
R. Kuner, P. Teismann, A. Trutzel, J. Naim, A. Richter, N. Schmidt, A. Bach, B. Ferger, and A. Schneider TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice Neurosci. Lett. 355 2004 126 130
-
(2004)
Neurosci. Lett.
, vol.355
, pp. 126-130
-
-
Kuner, R.1
Teismann, P.2
Trutzel, A.3
Naim, J.4
Richter, A.5
Schmidt, N.6
Bach, A.7
Ferger, B.8
Schneider, A.9
-
46
-
-
0026638820
-
Targeted oncogene activation by site-specific recombination in transgenic mice
-
M. Lakso, B. Sauer, B. Mosinger Jr., E.J. Lee, R.W. Manning, S.H. Yu, K.L. Mulder, and H. Westphal Targeted oncogene activation by site-specific recombination in transgenic mice Proc. Natl. Acad. Sci. U. S. A. 89 1992 6232 6236
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 6232-6236
-
-
Lakso, M.1
Sauer, B.2
Mosinger Jr., B.3
Lee, E.J.4
Manning, R.W.5
Yu, S.H.6
Mulder, K.L.7
Westphal, H.8
-
47
-
-
0028173680
-
Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
-
Y. Li, R.S. Erzurumlu, C. Chen, S. Jhaveri, and S. Tonegawa Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice Cell 76 1994 427 437
-
(1994)
Cell
, vol.76
, pp. 427-437
-
-
Li, Y.1
Erzurumlu, R.S.2
Chen, C.3
Jhaveri, S.4
Tonegawa, S.5
-
48
-
-
0034571235
-
DNA damage in brain mitochondria caused by aging and MPTP treatment
-
B.S. Mandavilli, S.F. Ali, and B. Van Houten DNA damage in brain mitochondria caused by aging and MPTP treatment Brain Res. 885 2000 45 52
-
(2000)
Brain Res.
, vol.885
, pp. 45-52
-
-
Mandavilli, B.S.1
Ali, S.F.2
Van Houten, B.3
-
49
-
-
0002701075
-
Production of targeted embryonic stem cell clones
-
A.L. Joyner Oxford Univ. Press Oxford
-
M.P. Matise, W. Auerbach, and A.L. Joyner Production of targeted embryonic stem cell clones A.L. Joyner Gene Targeting 2000 Oxford Univ. Press Oxford
-
(2000)
Gene Targeting
-
-
Matise, M.P.1
Auerbach, W.2
Joyner, A.L.3
-
50
-
-
0036846119
-
TorsinA and heat shock proteins act as molecular chaperones: Suppression of alpha-synuclein aggregation
-
P.J. McLean, H. Kawamata, S. Shariff, J. Hewett, N. Sharma, K. Ueda, X.O. Breakefield, and B.T. Hyman TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation J. Neurochem. 83 2002 846 854
-
(2002)
J. Neurochem.
, vol.83
, pp. 846-854
-
-
McLean, P.J.1
Kawamata, H.2
Shariff, S.3
Hewett, J.4
Sharma, N.5
Ueda, K.6
Breakefield, X.O.7
Hyman, B.T.8
-
51
-
-
4844225770
-
Brainstem pathology in DYT1 primary torsion dystonia
-
K.S. McNaught, A. Kapustin, T. Jackson, T.A. Jengelley, R. Jnobaptiste, P. Shashidharan, D.P. Perl, P. Pasik, and C.W. Olanow Brainstem pathology in DYT1 primary torsion dystonia Ann. Neurol. 56 2004 540 547
-
(2004)
Ann. Neurol.
, vol.56
, pp. 540-547
-
-
McNaught, K.S.1
Kapustin, A.2
Jackson, T.3
Jengelley, T.A.4
Jnobaptiste, R.5
Shashidharan, P.6
Perl, D.P.7
Pasik, P.8
Olanow, C.W.9
-
52
-
-
4544350592
-
Pedunculopontine nucleus and basal ganglia: Distant relatives or part of the same family?
-
J. Mena-Segovia, J.P. Bolam, and P.J. Magill Pedunculopontine nucleus and basal ganglia: distant relatives or part of the same family? Trends Neurosci. 27 2004 585 588
-
(2004)
Trends Neurosci.
, vol.27
, pp. 585-588
-
-
Mena-Segovia, J.1
Bolam, J.P.2
Magill, P.J.3
-
54
-
-
0034885052
-
AAA+ superfamily ATPases: Common structure-diverse function
-
T. Ogura, and A.J. Wilkinson AAA+ superfamily ATPases: common structure-diverse function Genes Cells 6 2001 575 597
-
(2001)
Genes Cells
, vol.6
, pp. 575-597
-
-
Ogura, T.1
Wilkinson, A.J.2
-
55
-
-
0036523711
-
Intrafamilial phenotypic variability of the DYT1 dystonia: From asymptomatic TOR1A gene carrier status to dystonic storm
-
P. Opal, R. Tintner, J. Jankovic, J. Leung, X.O. Breakefield, J. Friedman, and L. Ozelius Intrafamilial phenotypic variability of the DYT1 dystonia: from asymptomatic TOR1A gene carrier status to dystonic storm Mov. Disord. 17 2002 339 345
-
(2002)
Mov. Disord.
, vol.17
, pp. 339-345
-
-
Opal, P.1
Tintner, R.2
Jankovic, J.3
Leung, J.4
Breakefield, X.O.5
Friedman, J.6
Ozelius, L.7
-
56
-
-
16944366666
-
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein
-
L.J. Ozelius, J.W. Hewett, C.E. Page, S.B. Bressman, P.L. Kramer, C. Shalish, D. de Leon, M.F. Brin, D. Raymond, D.P. Corey, S. Fahn, N.J. Risch, A.J. Buckler, J.F. Gusella, and X.O. Breakefield The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein Nat. Genet. 17 1997 40 48
-
(1997)
Nat. Genet.
, vol.17
, pp. 40-48
-
-
Ozelius, L.J.1
Hewett, J.W.2
Page, C.E.3
Bressman, S.B.4
Kramer, P.L.5
Shalish, C.6
De Leon, D.7
Brin, M.F.8
Raymond, D.9
Corey, D.P.10
Fahn, S.11
Risch, N.J.12
Buckler, A.J.13
Gusella, J.F.14
Breakefield, X.O.15
-
57
-
-
0031609551
-
The gene (DYT1) for early-onset torsion dystonia encodes a novel protein related to the Clp protease/heat shock family
-
L.J. Ozelius, J.W. Hewett, C.E. Page, S.B. Bressman, P.L. Kramer, C. Shalish, D. de Leon, M.F. Brin, D. Raymond, D. Jacoby, J. Penney, N.J. Risch, S. Fahn, J.F. Gusella, and X.O. Breakefield The gene (DYT1) for early-onset torsion dystonia encodes a novel protein related to the Clp protease/heat shock family Adv. Neurol. 78 1998 93 105
-
(1998)
Adv. Neurol.
, vol.78
, pp. 93-105
-
-
Ozelius, L.J.1
Hewett, J.W.2
Page, C.E.3
Bressman, S.B.4
Kramer, P.L.5
Shalish, C.6
De Leon, D.7
Brin, M.F.8
Raymond, D.9
Jacoby, D.10
Penney, J.11
Risch, N.J.12
Fahn, S.13
Gusella, J.F.14
Breakefield, X.O.15
-
58
-
-
0033847609
-
The pedunculopontine nucleus and Parkinson's disease
-
P.A. Pahapill, and A.M. Lozano The pedunculopontine nucleus and Parkinson's disease Brain 123 Pt. 9 2000 1767 1783
-
(2000)
Brain
, vol.123
, Issue.PART 9
, pp. 1767-1783
-
-
Pahapill, P.A.1
Lozano, A.M.2
-
59
-
-
0000254621
-
Production of chimeras by blastocyst and morula injection of targeted ES cells
-
A.L. Joyner Oxford Univ. Press Oxford
-
V. Papaioannou, and R. Johnson Production of chimeras by blastocyst and morula injection of targeted ES cells A.L. Joyner Gene Targeting 2000 Oxford Univ. Press Oxford
-
(2000)
Gene Targeting
-
-
Papaioannou, V.1
Johnson, R.2
-
60
-
-
0037290217
-
PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine], a new MAO-B inhibitor, attenuates MPTP-induced depletion of striatal dopamine levels in C57/BL6 mice
-
V. Perez, and M. Unzeta PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine], a new MAO-B inhibitor, attenuates MPTP-induced depletion of striatal dopamine levels in C57/BL6 mice Neurochem. Int. 42 2003 221 229
-
(2003)
Neurochem. Int.
, vol.42
, pp. 221-229
-
-
Perez, V.1
Unzeta, M.2
-
61
-
-
0030659028
-
MPTP induces dystonia and parkinsonism. Clues to the pathophysiology of dystonia
-
J.S. Perlmutter, L.W. Tempel, K.J. Black, D. Parkinson, and R.D. Todd MPTP induces dystonia and parkinsonism. Clues to the pathophysiology of dystonia Neurology 49 1997 1432 1438
-
(1997)
Neurology
, vol.49
, pp. 1432-1438
-
-
Perlmutter, J.S.1
Tempel, L.W.2
Black, K.J.3
Parkinson, D.4
Todd, R.D.5
-
63
-
-
0037329443
-
TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion
-
K. Rostasy, S.J. Augood, J.W. Hewett, J.C. Leung, H. Sasaki, L.J. Ozelius, V. Ramesh, D.G. Standaert, X.O. Breakefield, and J.C. Hedreen TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion Neurobiol. Dis. 12 2003 11 24
-
(2003)
Neurobiol. Dis.
, vol.12
, pp. 11-24
-
-
Rostasy, K.1
Augood, S.J.2
Hewett, J.W.3
Leung, J.C.4
Sasaki, H.5
Ozelius, L.J.6
Ramesh, V.7
Standaert, D.G.8
Breakefield, X.O.9
Hedreen, J.C.10
-
64
-
-
0035404388
-
A close association of torsinA and alpha-synuclein in Lewy bodies: A fluorescence resonance energy transfer study
-
N. Sharma, J. Hewett, L.J. Ozelius, V. Ramesh, P.J. McLean, X.O. Breakefield, and B.T. Hyman A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study Am. J. Pathol. 159 2001 339 344
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 339-344
-
-
Sharma, N.1
Hewett, J.2
Ozelius, L.J.3
Ramesh, V.4
McLean, P.J.5
Breakefield, X.O.6
Hyman, B.T.7
-
65
-
-
20044374519
-
Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation
-
N. Sharma, M.G. Baxter, J. Petravicz, D.C. Bragg, A. Schienda, D.G. Standaert, and X.O. Breakefield Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation J. Neurosci. 25 2005 5351 5355
-
(2005)
J. Neurosci.
, vol.25
, pp. 5351-5355
-
-
Sharma, N.1
Baxter, M.G.2
Petravicz, J.3
Bragg, D.C.4
Schienda, A.5
Standaert, D.G.6
Breakefield, X.O.7
-
66
-
-
0033987354
-
Immunohistochemical localization and distribution of torsinA in normal human and rat brain
-
P. Shashidharan, B.C. Kramer, R.H. Walker, C.W. Olanow, and M.F. Brin Immunohistochemical localization and distribution of torsinA in normal human and rat brain Brain Res. 853 2000 197 206
-
(2000)
Brain Res.
, vol.853
, pp. 197-206
-
-
Shashidharan, P.1
Kramer, B.C.2
Walker, R.H.3
Olanow, C.W.4
Brin, M.F.5
-
68
-
-
1042289634
-
Overexpression of torsinA in PC12 cells protects against toxicity
-
P. Shashidharan, N. Paris, D. Sandu, L. Karthikeyan, K.S. McNaught, R.H. Walker, and C.W. Olanow Overexpression of torsinA in PC12 cells protects against toxicity J. Neurochem. 88 2004 1019 1025
-
(2004)
J. Neurochem.
, vol.88
, pp. 1019-1025
-
-
Shashidharan, P.1
Paris, N.2
Sandu, D.3
Karthikeyan, L.4
McNaught, K.S.5
Walker, R.H.6
Olanow, C.W.7
-
69
-
-
19944429223
-
Transgenic mouse model of early-onset DYT1 dystonia
-
P. Shashidharan, D. Sandu, U. Potla, I.A. Armata, R.H. Walker, K.S. McNaught, D. Weisz, T. Sreenath, M.F. Brin, and C.W. Olanow Transgenic mouse model of early-onset DYT1 dystonia Hum. Mol. Genet. 14 2005 125 133
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 125-133
-
-
Shashidharan, P.1
Sandu, D.2
Potla, U.3
Armata, I.A.4
Walker, R.H.5
McNaught, K.S.6
Weisz, D.7
Sreenath, T.8
Brin, M.F.9
Olanow, C.W.10
-
71
-
-
8144230422
-
Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant
-
G.E. Torres, A.L. Sweeney, J.M. Beaulieu, P. Shashidharan, and M.G. Caron Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant Proc. Natl. Acad. Sci. U. S. A. 101 2004 15650 15655
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15650-15655
-
-
Torres, G.E.1
Sweeney, A.L.2
Beaulieu, J.M.3
Shashidharan, P.4
Caron, M.G.5
-
72
-
-
0242575023
-
Dopamine phenotype and behaviour in animal models: In relation to attention deficit hyperactivity disorder
-
D. Viggiano, L.A. Ruocco, and A.G. Sadile Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder Neurosci. Biobehav. Rev. 27 2003 623 637
-
(2003)
Neurosci. Biobehav. Rev.
, vol.27
, pp. 623-637
-
-
Viggiano, D.1
Ruocco, L.A.2
Sadile, A.G.3
-
73
-
-
0035844053
-
Distribution and immunohistochemical characterization of torsinA immunoreactivity in rat brain
-
R.H. Walker, M.F. Brin, D. Sandu, P. Gujjari, P.R. Hof, C. Warren Olanow, and P. Shashidharan Distribution and immunohistochemical characterization of torsinA immunoreactivity in rat brain Brain Res. 900 2001 348 354
-
(2001)
Brain Res.
, vol.900
, pp. 348-354
-
-
Walker, R.H.1
Brin, M.F.2
Sandu, D.3
Gujjari, P.4
Hof, P.R.5
Warren Olanow, C.6
Shashidharan, P.7
-
74
-
-
0030780877
-
Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors
-
M. Xu, T.E. Koeltzow, G.T. Santiago, R. Moratalla, D.C. Cooper, X.T. Hu, N.M. White, A.M. Graybiel, F.J. White, and S. Tonegawa Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors Neuron 19 1997 837 848
-
(1997)
Neuron
, vol.19
, pp. 837-848
-
-
Xu, M.1
Koeltzow, T.E.2
Santiago, G.T.3
Moratalla, R.4
Cooper, D.C.5
Hu, X.T.6
White, N.M.7
Graybiel, A.M.8
White, F.J.9
Tonegawa, S.10
-
75
-
-
0033769461
-
Estrogen and progesterone distinctively modulate methamphetamine-induced dopamine and serotonin depletions in C57BL/6J mice
-
L. Yu, and P.C. Liao Estrogen and progesterone distinctively modulate methamphetamine-induced dopamine and serotonin depletions in C57BL/6J mice J. Neural Transm. 107 2000 1139 1147
-
(2000)
J. Neural Transm.
, vol.107
, pp. 1139-1147
-
-
Yu, L.1
Liao, P.C.2
-
76
-
-
0035852691
-
Hyperactivity and impaired response habituation in hyperdopaminergic mice
-
X. Zhuang, R.S. Oosting, S.R. Jones, R.R. Gainetdinov, G.W. Miller, M.G. Caron, and R. Hen Hyperactivity and impaired response habituation in hyperdopaminergic mice Proc. Natl. Acad. Sci. U. S. A. 98 2001 1982 1987
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 1982-1987
-
-
Zhuang, X.1
Oosting, R.S.2
Jones, S.R.3
Gainetdinov, R.R.4
Miller, G.W.5
Caron, M.G.6
Hen, R.7
-
77
-
-
0024324149
-
The pedunculopontine nucleus in Parkinson's disease
-
R.M. Zweig, W.R. Jankel, J.C. Hedreen, R. Mayeux, and D.L. Price The pedunculopontine nucleus in Parkinson's disease Ann. Neurol. 26 1989 41 46
-
(1989)
Ann. Neurol.
, vol.26
, pp. 41-46
-
-
Zweig, R.M.1
Jankel, W.R.2
Hedreen, J.C.3
Mayeux, R.4
Price, D.L.5
|