Arecoline inhibits intermediate-conductance calcium-activated potassium channels in human glioblastoma cell lines

European Journal of Pharmacology

Volumn 758, Issue , 2015, Pages 177-187

  So, Edmund Cheung ^a,b,c   Huang, Yan Ming ^d   Hsing, Chung Hsi ^e   Liao, Yu Kai ^d   Wu, Sheng Nan ^d  

^a Tainan Municipal An Nan Hospital China Medical University   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c SHANDONG UNIVERSITY   (China)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

Arecoline; Glioma cells; Intermediate conductance Ca^{2+< sup> activated; K+< sup> channel; K+< sup> current}

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; ARECOLINE; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MUSCARINIC RECEPTOR; POTASSIUM ION; VOLTAGE GATED POTASSIUM CHANNEL; 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE; BENZIMIDAZOLE DERIVATIVE; KCNMA1 PROTEIN, HUMAN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; POTASSIUM CHANNEL BLOCKING AGENT; PYRAZOLE DERIVATIVE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG MECHANISM; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; INHIBITION KINETICS; INTRACELLULAR RECORDING; KERATINOCYTE; MEMBRANE DEPOLARIZATION; METABOLIC INHIBITION; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; PRIORITY JOURNAL; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; U373 CELL LINE; U87MG CELL LINE; WHOLE CELL; ANTAGONISTS AND INHIBITORS; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; KINETICS; MEMBRANE POTENTIAL; PRIMARY CELL CULTURE; TUMOR CELL LINE;

ARECOLINE; BENZIMIDAZOLES; CELL LINE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MEMBRANE POTENTIALS; POTASSIUM CHANNEL BLOCKERS; PRIMARY CELL CULTURE; PYRAZOLES;

EID: 84928549683     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.03.065     Document Type: Article

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