Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Xu, Heyang ^a   Lai, Wei ^a   Zhang, Yang ^a   Liu, Lu ^a   Luo, Xingxi ^a   Zeng, Yujie ^a   Wu, Heng ^a   Lan, Qiusheng ^a   Chu, Zhonghua ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

CRC; IL 6; IL 8; KCNN4; PRL 3; Tumor associated macrophage

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; CD68 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PROTEIN PRL 3; PROTEIN TYROSINE PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; KCNN4 PROTEIN, HUMAN; POTASSIUM CHANNEL BLOCKING AGENT; PTP4A3 PROTEIN, HUMAN; TUMOR PROTEIN;

AGED; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL INVASION; CELL INVASION ASSAY; CHROMATIN IMMUNOPRECIPITATION; COCULTURE; COLORECTAL CANCER; COLORECTAL LIVER METASTASIS; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MALE; PARACRINE SIGNALING; PROTEIN BINDING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; TUMOR PROMOTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BINDING SITE; CELL MOTION; COLON TUMOR; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; PATHOLOGY; PROMOTER REGION; TIME; TUMOR CELL LINE; TUMOR INVASION;

BINDING SITES; CELL LINE, TUMOR; CELL MOVEMENT; COCULTURE TECHNIQUES; COLONIC NEOPLASMS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MACROPHAGES; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NF-KAPPA B; PARACRINE COMMUNICATION; POTASSIUM CHANNEL BLOCKERS; PROMOTER REGIONS, GENETIC; PROTEIN TYROSINE PHOSPHATASES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR MICROENVIRONMENT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900841536     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-330     Document Type: Article

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