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Volumn 44, Issue 12, 2009, Pages 4848-4854
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Synthesis and pharmacological evaluation of novel N-alkyl/aryl substituted thiazolidinone arecoline analogues as muscarinic receptor 1 agonist in Alzheimer's dementia models
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Author keywords
Alzheimer's disease; Arecoline derivatives; M1 receptor binding; Thiazolidinones
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Indexed keywords
2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) 3 (4 NITROPHENYL) THIAZOLIDIN 4 ONE;
2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) 3 (4 PHENYLAMINO PHENYL) THIAZOLIDIN 4 ONE;
2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) 3 PHENYL THIAZOLIDIN 4 ONE;
3 (3 HYDROXY PHENYL) 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 (4 AMINO BUTYL) 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 (4 BROMOPHENYL) 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 (4 CHLOROPHENYL) 2 (1,2,5,6 TETRAHYDRO 1 METHYLPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 (4 METHYL 2 NITRO PHENYL) 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 BENZYL 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 ETHYL 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN YL) THIAZOLIDIN 4 ONE;
3 HEXYL 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 ISOPROPYL 2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) THIAZOLIDIN 4 ONE;
3 PYRIDINE CARBOXALDEHYDE;
4 [2 (1 METHYL 1,2,5,6 TETRAHYDROPYRIDIN 3 YL) 4 OXO THIAZOLIDIN 3 YL] BENZOIC ACID;
ALDEHYDE DERIVATIVE;
AMINE;
ARECOLINE;
DIPHENYLAMINE;
FERRITE;
MUSCARINIC RECEPTOR;
NITROGEN;
UNCLASSIFIED DRUG;
ALZHEIMER DISEASE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ARTICLE;
BINDING AFFINITY;
BRAIN HOMOGENATE;
CATALYST;
CONTROLLED STUDY;
DRUG SYNTHESIS;
IN VIVO STUDY;
LEARNING;
MALE;
MEMORY;
NONHUMAN;
RAT;
RECEPTOR BINDING;
ALZHEIMER DISEASE;
ANIMALS;
ARECOLINE;
BRAIN;
DISEASE MODELS, ANIMAL;
MALE;
MEMORY;
MOLECULAR STRUCTURE;
MUSCARINIC AGONISTS;
RATS;
RATS, WISTAR;
RECEPTOR, MUSCARINIC M1;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIAZOLIDINES;
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EID: 70449625291
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2009.07.026 Document Type: Article |
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Times cited : (52)
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References (27)
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