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Volumn 17, Issue 4, 2013, Pages 552-566

M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells

Author keywords

Apoptosis; Arecaidine; Cell cycle; Glioblastoma; M2 muscarinic receptors; Proliferation

Indexed keywords

ANTINEOPLASTIC AGENT; ARECAIDINE; ARECOLINE; DRUG DERIVATIVE; MUSCARINIC AGENT; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84877019142     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12038     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 27744589455 scopus 로고    scopus 로고
    • Muscarinic receptor subtype pharmacology and physiology
    • Eglen RM. Muscarinic receptor subtype pharmacology and physiology. Prog Med Chem. 2005; 43: 105-36.
    • (2005) Prog Med Chem , vol.43 , pp. 105-136
    • Eglen, R.M.1
  • 2
    • 0030608436 scopus 로고    scopus 로고
    • Carbachol stimulates c-fos expression and proliferation in oligodendrocyte progenitors
    • Cohen RI, Molina-Holgado E, Almazan G. Carbachol stimulates c-fos expression and proliferation in oligodendrocyte progenitors. Mol Brain Res. 1996; 43: 193-201.
    • (1996) Mol Brain Res , vol.43 , pp. 193-201
    • Cohen, R.I.1    Molina-Holgado, E.2    Almazan, G.3
  • 3
    • 0030699250 scopus 로고    scopus 로고
    • Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors
    • Larocca JN, Alzman G. Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors. J Neurosci. 1997; 50: 743-54.
    • (1997) J Neurosci , vol.50 , pp. 743-754
    • Larocca, J.N.1    Alzman, G.2
  • 4
    • 46749115525 scopus 로고    scopus 로고
    • Acetylcholine inhibits cell cycle progression in rat Schwann cells by activation of the M2 receptor subtype
    • Loreti S, Ricordy R, De Stefano ME, et al. Acetylcholine inhibits cell cycle progression in rat Schwann cells by activation of the M2 receptor subtype. Neuron Glia Biol. 2007; 3: 269-79.
    • (2007) Neuron Glia Biol , vol.3 , pp. 269-279
    • Loreti, S.1    Ricordy, R.2    De Stefano, M.E.3
  • 5
    • 0035016227 scopus 로고    scopus 로고
    • Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes
    • Ragheb F, Molina-Holgado E, Cui Q, et al. Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes. J Neurochem. 2001; 77: 1396-406.
    • (2001) J Neurochem , vol.77 , pp. 1396-1406
    • Ragheb, F.1    Molina-Holgado, E.2    Cui, Q.3
  • 6
    • 84859492260 scopus 로고    scopus 로고
    • Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation and differentiation
    • De Angelis F, Bernardo A, Magnaghi V, et al. Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation and differentiation. Develop Neurobiol. 2012; 72: 713-28.
    • (2012) Develop Neurobiol , vol.72 , pp. 713-728
    • De Angelis, F.1    Bernardo, A.2    Magnaghi, V.3
  • 7
    • 33745767930 scopus 로고    scopus 로고
    • Rat Schwann Cells express M1-M4 muscarinic receptor subtypes
    • Loreti S, Vilarò MT, Visentin S, et al. Rat Schwann Cells express M1-M4 muscarinic receptor subtypes. J Neurosci Res. 2006; 84: 97-105.
    • (2006) J Neurosci Res , vol.84 , pp. 97-105
    • Loreti, S.1    Vilarò, M.T.2    Visentin, S.3
  • 8
    • 3342913105 scopus 로고    scopus 로고
    • Signaling cascades implicated in muscarinic regulation of proliferation of neural stem and progenitor cells
    • Ma W, Li BS, Zhang L, et al. Signaling cascades implicated in muscarinic regulation of proliferation of neural stem and progenitor cells. Drug News Perspect. 2004; 17: 258-66.
    • (2004) Drug News Perspect , vol.17 , pp. 258-266
    • Ma, W.1    Li, B.S.2    Zhang, L.3
  • 9
    • 0842327743 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors involved in the regulation of neural stem cell proliferation and differentiation in vitro
    • Zhou C, Wen ZX, Shi DM, et al. Muscarinic acetylcholine receptors involved in the regulation of neural stem cell proliferation and differentiation in vitro. Cell Biol Inter. 2004; 28: 63-7.
    • (2004) Cell Biol Inter , vol.28 , pp. 63-67
    • Zhou, C.1    Wen, Z.X.2    Shi, D.M.3
  • 10
    • 0034676312 scopus 로고    scopus 로고
    • Therapeutic opportunities for muscarinic receptors in the central nervous system
    • Felder CC, Baymaster FP, Ward J, et al. Therapeutic opportunities for muscarinic receptors in the central nervous system. J Med Chem. 2000; 43: 4333-53.
    • (2000) J Med Chem , vol.43 , pp. 4333-4353
    • Felder, C.C.1    Baymaster, F.P.2    Ward, J.3
  • 11
    • 9644281566 scopus 로고    scopus 로고
    • Decreased amphetamine-induced locomotion and improved latent inhibition in mice mutant for the M5 muscarinic receptor gene found in human 15q schizophrenia region
    • Wang H, NG K, Hayes D, et al. Decreased amphetamine-induced locomotion and improved latent inhibition in mice mutant for the M5 muscarinic receptor gene found in human 15q schizophrenia region. Neuropsychopharmacol. 2005; 29: 2126-39.
    • (2005) Neuropsychopharmacol , vol.29 , pp. 2126-2139
    • Wang, H.1    Ng, K.2    Hayes, D.3
  • 12
    • 49149088469 scopus 로고    scopus 로고
    • Muscarinic Acetylcholine receptors: new potential therapeutic targets in antinociception and in cancer therapy
    • Tata AM. Muscarinic Acetylcholine receptors: new potential therapeutic targets in antinociception and in cancer therapy. Rec Patents in CNS Drug Discov. 2008; 3: 1-10.
    • (2008) Rec Patents in CNS Drug Discov , vol.3 , pp. 1-10
    • Tata, A.M.1
  • 14
    • 33644643568 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors mediate survival through Src-like tyrosine kinase and PI3K/AKT pathways
    • Cui QL, Fogle E, Almazan G. Muscarinic acetylcholine receptors mediate survival through Src-like tyrosine kinase and PI3K/AKT pathways. Neurochem Int. 2006; 48: 383-93.
    • (2006) Neurochem Int , vol.48 , pp. 383-393
    • Cui, Q.L.1    Fogle, E.2    Almazan, G.3
  • 15
    • 0026164317 scopus 로고
    • Activation of muscarinic acetylcholine receptors inhibits cell cycle progression of small cell lung carcinoma
    • Williams CL, Lennon A. Activation of muscarinic acetylcholine receptors inhibits cell cycle progression of small cell lung carcinoma. Cell Regulation. 1991; 2: 373-81.
    • (1991) Cell Regulation , vol.2 , pp. 373-381
    • Williams, C.L.1    Lennon, A.2
  • 16
    • 0030975255 scopus 로고    scopus 로고
    • Muscarinic cholinergic receptors promote growth of human prostate cancer cells
    • Rayford W, Noble MJ, Austenfeld MA, et al. Muscarinic cholinergic receptors promote growth of human prostate cancer cells. Prostate. 1997; 30: 160-6.
    • (1997) Prostate , vol.30 , pp. 160-166
    • Rayford, W.1    Noble, M.J.2    Austenfeld, M.A.3
  • 17
    • 0032884778 scopus 로고    scopus 로고
    • Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor
    • Frucht H, Jensen RT, Dexter D, et al. Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor. Clinical Cancer Res. 1999; 5: 2532-9.
    • (1999) Clinical Cancer Res , vol.5 , pp. 2532-2539
    • Frucht, H.1    Jensen, R.T.2    Dexter, D.3
  • 18
    • 0036223172 scopus 로고    scopus 로고
    • Muscarinic receptors in cell lines from ovarian carcinoma: negative correlation with survival of patients
    • Oppitz M, Möbus V, Brock S, et al. Muscarinic receptors in cell lines from ovarian carcinoma: negative correlation with survival of patients. Gynecologic Oncol. 2002; 85: 159-64.
    • (2002) Gynecologic Oncol , vol.85 , pp. 159-164
    • Oppitz, M.1    Möbus, V.2    Brock, S.3
  • 19
    • 34248597724 scopus 로고    scopus 로고
    • M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion
    • Song P, Sekhon HS, Lu A, et al. M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion. Cancer Res. 2007; 67: 3936-44.
    • (2007) Cancer Res , vol.67 , pp. 3936-3944
    • Song, P.1    Sekhon, H.S.2    Lu, A.3
  • 20
    • 23044493073 scopus 로고    scopus 로고
    • Muscarinic cholinergic receptors in the human melanoma cell line SK-Mel 28: modulation of chemotaxis
    • Boss A, Oppitz M, Drews U. Muscarinic cholinergic receptors in the human melanoma cell line SK-Mel 28: modulation of chemotaxis. Clin Exp Dermatol. 2005; 30: 557-64.
    • (2005) Clin Exp Dermatol , vol.30 , pp. 557-564
    • Boss, A.1    Oppitz, M.2    Drews, U.3
  • 21
    • 23044498654 scopus 로고    scopus 로고
    • Muscarinic receptors are involved in LMM3 tumor cells proliferation and angiogenesis
    • Rimmaudo LE, De La Torre E, Sacerdote de Lustig E, et al. Muscarinic receptors are involved in LMM3 tumor cells proliferation and angiogenesis. Bioch Bioph Res Com. 2005; 334: 1359-64.
    • (2005) Bioch Bioph Res Com , vol.334 , pp. 1359-1364
    • Rimmaudo, L.E.1    De La Torre, E.2    Sacerdote de Lustig, E.3
  • 22
    • 21644452109 scopus 로고    scopus 로고
    • Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells
    • Jiménez E, Montiel M. Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. J Cell Physiol. 2005; 204: 678-86.
    • (2005) J Cell Physiol , vol.204 , pp. 678-686
    • Jiménez, E.1    Montiel, M.2
  • 23
    • 49349096359 scopus 로고    scopus 로고
    • Distribution of muscarinic receptor subtype M3 in melanomas and their metastases
    • Oppitz M, Busch G, Garbe C, et al. Distribution of muscarinic receptor subtype M3 in melanomas and their metastases. J Cutan Pathol. 2008; 35: 809-15.
    • (2008) J Cutan Pathol , vol.35 , pp. 809-815
    • Oppitz, M.1    Busch, G.2    Garbe, C.3
  • 24
    • 0037229715 scopus 로고    scopus 로고
    • Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma
    • Song P, Harmanjatider S, Sekhon S, et al. Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma. Cancer Res. 2003; 63: 214-21.
    • (2003) Cancer Res , vol.63 , pp. 214-221
    • Song, P.1    Harmanjatider, S.2    Sekhon, S.3
  • 25
    • 0022560625 scopus 로고
    • Astrocytes have both M1 and M2 muscarinic receptor subtypes
    • Murphy S, Pearce B, Morrow C. Astrocytes have both M1 and M2 muscarinic receptor subtypes. Brain Res. 1986; 364: 177-80.
    • (1986) Brain Res , vol.364 , pp. 177-180
    • Murphy, S.1    Pearce, B.2    Morrow, C.3
  • 26
    • 0030064643 scopus 로고    scopus 로고
    • Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells
    • Guizzetti M, Costa P, Peters J, et al. Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells. Europ J Pharmacol. 1996; 297: 265-73.
    • (1996) Europ J Pharmacol , vol.297 , pp. 265-273
    • Guizzetti, M.1    Costa, P.2    Peters, J.3
  • 27
    • 84859502745 scopus 로고    scopus 로고
    • Muscarinic receptors and cancer: possible implications in tumors of the nervous system
    • Tata AM, Calogero A. Muscarinic receptors and cancer: possible implications in tumors of the nervous system. Curr Trends in Neurol. 2010; 4: 23-31.
    • (2010) Curr Trends in Neurol , vol.4 , pp. 23-31
    • Tata, A.M.1    Calogero, A.2
  • 28
    • 84872808405 scopus 로고    scopus 로고
    • M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines
    • Ferretti M, Fabbiano C, Di Bari M, et al. M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines. Life Sci. 2012; 91: 1134-37.
    • (2012) Life Sci , vol.91 , pp. 1134-1137
    • Ferretti, M.1    Fabbiano, C.2    Di Bari, M.3
  • 29
    • 79952083939 scopus 로고    scopus 로고
    • Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression
    • Calogero A, Porcellini A, Lombari V, et al. Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression. Cancer Cell Int. 2011; 2: 11-5.
    • (2011) Cancer Cell Int , vol.2 , pp. 11-15
    • Calogero, A.1    Porcellini, A.2    Lombari, V.3
  • 30
    • 0024310021 scopus 로고
    • High-performance liquid chromatographic determination of the alkaloids in betel nut
    • Huang JL, McLeish MJ. High-performance liquid chromatographic determination of the alkaloids in betel nut. J Chromatogr. 1989; 475: 447-50.
    • (1989) J Chromatogr , vol.475 , pp. 447-450
    • Huang, J.L.1    McLeish, M.J.2
  • 31
    • 0022401722 scopus 로고
    • The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi
    • Barlow RB, Weston-Smith P. The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br J Pharmacol. 1985; 85: 437-40.
    • (1985) Br J Pharmacol , vol.85 , pp. 437-440
    • Barlow, R.B.1    Weston-Smith, P.2
  • 32
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosman, T.1
  • 33
    • 0030953165 scopus 로고    scopus 로고
    • Deregulated apoptosis is a hallmark of Fanconi anemia syndrome
    • Ridet A, Guillouf C, Duchaud E, et al. Deregulated apoptosis is a hallmark of Fanconi anemia syndrome. Canc Res. 1997; 57: 1722-30.
    • (1997) Canc Res , vol.57 , pp. 1722-1730
    • Ridet, A.1    Guillouf, C.2    Duchaud, E.3
  • 34
    • 0026492817 scopus 로고
    • Features of apoptotic cells measured by flow cytometry
    • Darzynkiewicz Z, Bruno S, Del Bino G, et al. Features of apoptotic cells measured by flow cytometry. Cytometry. 1992; 13: 795-808.
    • (1992) Cytometry , vol.13 , pp. 795-808
    • Darzynkiewicz, Z.1    Bruno, S.2    Del Bino, G.3
  • 35
    • 2942604975 scopus 로고    scopus 로고
    • Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma
    • Calogero A, Lombari V, De Gregorio G, et al. Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma. Cancer Cell Int. 2004; 4: 1-12.
    • (2004) Cancer Cell Int , vol.4 , pp. 1-12
    • Calogero, A.1    Lombari, V.2    De Gregorio, G.3
  • 36
    • 0034235510 scopus 로고    scopus 로고
    • Muscarinic activation of BK channels induces membrane oscillations in glioma cells and leads to inhibition of cell migration
    • Bordey A, Sontheimer H, Drouslard J. Muscarinic activation of BK channels induces membrane oscillations in glioma cells and leads to inhibition of cell migration. J Membrane Biol. 2000; 176: 31-40.
    • (2000) J Membrane Biol , vol.176 , pp. 31-40
    • Bordey, A.1    Sontheimer, H.2    Drouslard, J.3
  • 37
    • 58149190329 scopus 로고    scopus 로고
    • Glioma formation, cancer stem cells, and AKT signaling
    • Hambardzamyan D, Squatrito M, Carbajal E, et al. Glioma formation, cancer stem cells, and AKT signaling. Stem Cell Rep. 2008; 4: 203-10.
    • (2008) Stem Cell Rep , vol.4 , pp. 203-210
    • Hambardzamyan, D.1    Squatrito, M.2    Carbajal, E.3
  • 38
    • 0037251810 scopus 로고    scopus 로고
    • Rapid AKT activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
    • West KA, Brognard J, Clark AS, et al. Rapid AKT activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. J Clin Invest. 2003; 111: 81-90.
    • (2003) J Clin Invest , vol.111 , pp. 81-90
    • West, K.A.1    Brognard, J.2    Clark, A.S.3
  • 39
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and AKT in neural progenitors induces glioblastoma formation in mice
    • Holland EC, Celestino J, Dai C, et al. Combined activation of Ras and AKT in neural progenitors induces glioblastoma formation in mice. Nature Gen. 2000; 25: 55-7.
    • (2000) Nature Gen , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3
  • 40
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta. 2007; 1773: 1263-84.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1263-1284
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3
  • 41
    • 0033639021 scopus 로고    scopus 로고
    • Interleukin-1beta induces apoptosis in GL15 glioblastoma-derived human cell lines
    • Castigli E, Arcuri C, Giovagnoli L, et al. Interleukin-1beta induces apoptosis in GL15 glioblastoma-derived human cell lines. Am J Physiol Cell Physiol. 2000; 279: 2043-9.
    • (2000) Am J Physiol Cell Physiol , vol.279 , pp. 2043-2049
    • Castigli, E.1    Arcuri, C.2    Giovagnoli, L.3
  • 42
    • 33744471979 scopus 로고    scopus 로고
    • GL15 and U251 glioblastoma-derived human cell lines are peculiarly susceptible to induction of mitotic death by very low concentrations of okadaic acid
    • Castigli E, Sciaccaluga M, Schiavoni G, et al. GL15 and U251 glioblastoma-derived human cell lines are peculiarly susceptible to induction of mitotic death by very low concentrations of okadaic acid. Oncol Rep. 2006; 15: 463-70.
    • (2006) Oncol Rep , vol.15 , pp. 463-470
    • Castigli, E.1    Sciaccaluga, M.2    Schiavoni, G.3
  • 43
    • 67650860453 scopus 로고    scopus 로고
    • Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
    • Lu J, Kovach JS, Johnson F, et al. Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms. Proc Natl Acad Sci USA. 2009; 106: 11697-702.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11697-11702
    • Lu, J.1    Kovach, J.S.2    Johnson, F.3
  • 44
    • 53449087496 scopus 로고    scopus 로고
    • Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation
    • Cheng K, Samimi R, Xie G, et al. Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation. Am J Physiol Gastrointest Liver Physiol. 2008; 295: 591-7.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295 , pp. 591-597
    • Cheng, K.1    Samimi, R.2    Xie, G.3
  • 45
    • 84866137183 scopus 로고    scopus 로고
    • Autonomic dysfunction and anti-M2 and β1 receptor antibodies I Chagas disease patients
    • Thiers CA, Barbosa JL, Pereira BD, et al. Autonomic dysfunction and anti-M2 and β1 receptor antibodies I Chagas disease patients. Arq Bas Cardiol. 2012; 99: 732-9.
    • (2012) Arq Bas Cardiol , vol.99 , pp. 732-739
    • Thiers, C.A.1    Barbosa, J.L.2    Pereira, B.D.3
  • 46


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