Arecoline excites the contraction of distal colonic smooth muscle strips in rats via the M3 receptor - Extracellular Ca2+ influx -Ca2+ store release pathway

Canadian Journal of Physiology and Pharmacology

Volumn 88, Issue 4, 2010, Pages 439-447

  Li, Chuan Bao ^a   Yang, Xiao ^b   Tang, Wen Bo ^a   Liu, Chuan Yong ^a   Xie, Dong Ping ^b  

^a SHANDONG UNIVERSITY   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Arecoline; Ca2+ store release; Colon; Extracellular ca2+ influx; Intestinal motility; IP3 receptor; M2 and M3 receptors; Smooth muscle

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 4 (3 NITROPHENYL) 3,5 PYRIDINEDICARBOXYLIC ACID DIMETHYL ESTER; 2 AMINOETHOXYDIPHENYLBORANE; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ARECOLINE; ATROPINE; CALCIUM ION; GALLAMINE; METHOCTRAMINE; MUSCARINIC M3 RECEPTOR; TETRODOTOXIN; CALCIUM; CHOLINERGIC RECEPTOR STIMULATING AGENT; HERBACEOUS AGENT; MUSCARINIC AGENT; MUSCARINIC RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARECACEAE; ARTICLE; CALCIUM TRANSPORT; CHINESE; COLON MOTILITY; CONSTIPATION; CONTROLLED STUDY; DESCENDING COLON; DRUG MECHANISM; EXTRACELLULAR CALCIUM; FEMALE; HERBAL MEDICINE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOBREEDING RAT; COLON; DOSE RESPONSE; DRUG EFFECTS; IN VITRO STUDY; ION TRANSPORT; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

ANIMALS; ARECOLINE; CALCIUM; CHOLINERGIC AGONISTS; COLON; CONSTIPATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; IN VITRO TECHNIQUES; ION TRANSPORT; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED BB; RECEPTOR, MUSCARINIC M3; TETRODOTOXIN;

EID: 77952040816     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y10-024     Document Type: Article

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