Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Prielhofer, Roland ^a,b   Cartwright, Stephanie P ^c   Graf, Alexandra B ^b,d   Valli, Minoska ^a,b   Bill, Roslyn M ^c   Mattanovich, Diethard ^a,b   Gasser, Brigitte ^a,b  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^c ASTON UNIVERSITY   (United Kingdom)

^d Fachhochschule Campus Wien   (Austria)

Author keywords

Carbon substrate repression; Crabtree negative yeast; Glucose repression; Methanol induction; Methylotrophic yeast; Microarray analysis; Pichia pastoris; Polysome profiling; Transcriptome

Indexed keywords

GLUCOSE; GLYCEROL; MESSENGER RNA; CARBON; FUNGAL PROTEIN; METHANOL; TRANSCRIPTION FACTOR; TRANSCRIPTOME;

ARTICLE; CARBON METABOLISM; CARBON SOURCE; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; FUNGUS GROWTH; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE INDUCTION; GENE LOCATION; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLYCOLYSIS; KOMAGATAELLA PASTORIS; METABOLIC REGULATION; MICROARRAY ANALYSIS; NONHUMAN; OPEN READING FRAME; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; UPREGULATION; FUNGAL GENE; GENETICS; METABOLISM; PICHIA; PROTEIN SYNTHESIS;

PICHIA PASTORIS;

CARBON; FUNGAL PROTEINS; GENES, FUNGAL; GLUCONEOGENESIS; GLUCOSE; GLYCEROL; GLYCOLYSIS; METHANOL; PICHIA; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84928327289     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1393-8     Document Type: Article

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