In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response

Biotechnology Journal

Volumn 9, Issue 4, 2014, Pages 511-525

  Rebnegger, Corinna ^a   Graf, Alexandra B ^b,c   Valli, Minoska ^a,c   Steiger, Matthias G ^a,c   Gasser, Brigitte ^a,c   Maurer, Michael ^b,c   Mattanovich, Diethard ^a,c  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b Fachhochschule Campus Wien   (Austria)

^c AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

Filamentous growth; Recombinant protein secretion; Specific growth rate; Unfolded protein response; Yeast

Indexed keywords

CELL MEMBRANES; GENES; GLUCOSE; PHYSIOLOGY; PROTEIN FOLDING; PROTEINS; YEAST;

ENDOPLASMIC RETICULUM; FILAMENTOUS GROWTH; MULTIPLE CELLULAR PROCESS; PROTEOLYTIC DEGRADATION; RECOMBINANT PROTEIN SECRETION; SPECIFIC GROWTH RATE; TRANSCRIPTIONAL REGULATOR; UNFOLDED PROTEIN RESPONSE;

GROWTH RATE;

CARBON; CHAPERONE; FUNGAL PROTEIN; FUNGAL RNA; GLUCOSE; HUMAN SERUM ALBUMIN; SECRETORY PROTEIN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTOME; RECOMBINANT PROTEIN;

ARTICLE; AUTOPHAGY; CARBON SOURCE; CHEMOSTAT; CYTOSOL; DOWN REGULATION; ENDOPLASMIC RETICULUM; FUNGAL GENE; FUNGAL GENOME; FUNGAL STRAIN; FUNGUS GROWTH; GENE CONTROL; GENE TARGETING; GENE TRANSLOCATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GROWTH RATE; MATING; MITOCHONDRIAL GENE; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN SECRETION; PROTEIN SYNTHESIS; RNA TRANSLATION; SPOROGENESIS; STRESS; TRANSCRIPTION REGULATION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PICHIA;

PICHIA PASTORIS;

FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MODELS, BIOLOGICAL; PICHIA; RECOMBINANT PROTEINS; UNFOLDED PROTEIN RESPONSE;

EID: 84897420565     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201300334     Document Type: Article

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