Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha

Cellular Signalling

Volumn 27, Issue 7, 2015, Pages 1356-1368

  Hansen, Mariann F ^a   Greibe, Eva ^a,b   Skovbjerg, Signe ^a   Rohde, Sarah ^a   Kristensen, Anders C M ^a   Jensen, Trine R ^a   Stentoft, Charlotte ^a   Kjær, Karina H ^a   Kronborg, Camilla S ^a,b   Martensen, Pia M ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Folate Receptor; Folic acid; Gp130; STAT3; Vitamin B9

Indexed keywords

CYCLIN A2; FOLATE RECEPTOR 1; FOLIC ACID; FOLINIC ACID; GLYCOPROTEIN GP 130; JANUS KINASE; STAT3 PROTEIN; VASCULOTROPIN; INTERLEUKIN 6; SMALL INTERFERING RNA; STAT3 PROTEIN, HUMAN; VASCULOTROPIN A;

ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE ACTIVATION; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; NEURAL TUBE DEFECT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTO ONCOGENE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 PROTO ONCOGENE; TUMOR GROWTH; UPREGULATION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION;

CELL PROLIFERATION; CYCLIN A2; FOLATE RECEPTOR 1; FOLIC ACID; HEK293 CELLS; HELA CELLS; HUMANS; INTERLEUKIN-6; JANUS KINASES; LEUCOVORIN; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84927949416     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.03.020     Document Type: Article

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