Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124

Cell Death and Disease

Volumn 4, Issue 8, 2013, Pages

  Kerek, R ^a,b   Geoffroy, A ^a,b   Bison, A ^a,b   Martin, N ^a,b   Akchiche, N ^a,b   Pourie G ^a,b   Helle, D ^a,b   Gueant J L ^a,b,c   Bossenmeyer Pourie C ^a,b   Daval, J L ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c OASI RESEARCH INSTITUTE IRCCS   (Italy)

Author keywords

Brain development; Epigenetics; Folate; MiR 124; Stat3; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; MICRORNA 124; PROTEIN BCL 2; PROTEIN BCL XL; STAT3 PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN DISEASE; BRAIN WEIGHT; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DOWN REGULATION; FEMALE; FOLIC ACID DEFICIENCY; GROWTH RETARDATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MORPHOMETRICS; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BRAIN; BRAIN DISEASES; CELL LINE; FETAL DEVELOPMENT; FOLIC ACID; HIPPOCAMPUS; MICRORNAS; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VITAMIN B 12 DEFICIENCY;

EID: 84882677292     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.278     Document Type: Article

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