메뉴 건너뛰기




Volumn 26, Issue 9, 2007, Pages 2400-2410

A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

Author keywords

Antigenic variation; ISWI; Monoallelic expression; Regulated domains; Trypanosoma brucei

Indexed keywords

PROTEIN ISWI; PROTEIN SWI; PROTOZOAL PROTEIN; TRANSCRIPTION FACTOR SNF; UNCLASSIFIED DRUG; VARIANT SURFACE GLYCOPROTEIN;

EID: 34247572533     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601678     Document Type: Article
Times cited : (78)

References (49)
  • 1
    • 25144506072 scopus 로고    scopus 로고
    • VSG switching in Trypanosoma brucei: Antigenic variation analysed using RNAi in the absence of immune selection
    • Aitcheson N, Talbot S, Shapiro J, Hughes K, Adkin C, Butt T, Sheader K, Rudenko G (2005) VSG switching in Trypanosoma brucei: antigenic variation analysed using RNAi in the absence of immune selection. Mol Microbiol 57: 1608-1622
    • (2005) Mol Microbiol , vol.57 , pp. 1608-1622
    • Aitcheson, N.1    Talbot, S.2    Shapiro, J.3    Hughes, K.4    Adkin, C.5    Butt, T.6    Sheader, K.7    Rudenko, G.8
  • 2
    • 25844451002 scopus 로고    scopus 로고
    • Downregulation of the essential Trypanosoma brucei La protein affects accumulation of elongator methionyl-tRNA
    • Arhin GK, Shen S, Perez IF, Tschudi C, Ullu E (2005) Downregulation of the essential Trypanosoma brucei La protein affects accumulation of elongator methionyl-tRNA. Mol Biochem Parasitol 144: 104-108
    • (2005) Mol Biochem Parasitol , vol.144 , pp. 104-108
    • Arhin, G.K.1    Shen, S.2    Perez, I.F.3    Tschudi, C.4    Ullu, E.5
  • 3
    • 0027275067 scopus 로고
    • Molecular cloning and cellular localization of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals in a lower eukaryote
    • Bangs JD, Uyetake L, Brickman MJ, Balber AE, Boothroyd JC (1993) Molecular cloning and cellular localization of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals in a lower eukaryote. J Cell Sci 105: 1101-1113
    • (1993) J Cell Sci , vol.105 , pp. 1101-1113
    • Bangs, J.D.1    Uyetake, L.2    Brickman, M.J.3    Balber, A.E.4    Boothroyd, J.C.5
  • 4
    • 0035222844 scopus 로고    scopus 로고
    • Antigenic variation in trypanosomes: Enhanced phenotypic variation in a eukaryotic parasite
    • Barry JD, McCulloch R (2001) Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite. Adv Parasitol 49: 1-70
    • (2001) Adv Parasitol , vol.49 , pp. 1-70
    • Barry, J.D.1    McCulloch, R.2
  • 5
    • 8744298412 scopus 로고    scopus 로고
    • Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast
    • Becker M, Aitcheson N, Byles E, Wickstead B, Louis E, Rudenko G (2004) Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast. Genome Res 14: 2319-2329
    • (2004) Genome Res , vol.14 , pp. 2319-2329
    • Becker, M.1    Aitcheson, N.2    Byles, E.3    Wickstead, B.4    Louis, E.5    Rudenko, G.6
  • 6
    • 22244441812 scopus 로고    scopus 로고
    • Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Bohme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertezak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM
    • Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Bohme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertezak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM (2005) The genome of the African trypanosome Trypanosoma brucei. Science 309: 416-422
  • 7
    • 0035946390 scopus 로고    scopus 로고
    • Control of VSG gene expression sites
    • Borst P, Ulbert S (2001) Control of VSG gene expression sites. Mol Biochem Parasitol 114: 17-27
    • (2001) Mol Biochem Parasitol , vol.114 , pp. 17-27
    • Borst, P.1    Ulbert, S.2
  • 8
    • 0036809731 scopus 로고    scopus 로고
    • Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes
    • Boyer LA, Langer MR, Crowley KA, Tan S, Denu JM, Peterson CL (2002) Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol Cell 10: 935-942
    • (2002) Mol Cell , vol.10 , pp. 935-942
    • Boyer, L.A.1    Langer, M.R.2    Crowley, K.A.3    Tan, S.4    Denu, J.M.5    Peterson, C.L.6
  • 10
    • 0033199568 scopus 로고    scopus 로고
    • Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei
    • Chaves I, Rudenko G, Dirks-Mulder A, Cross M, Borst P (1999) Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei. EMBOJ 18: 4846-4855
    • (1999) EMBOJ , vol.18 , pp. 4846-4855
    • Chaves, I.1    Rudenko, G.2    Dirks-Mulder, A.3    Cross, M.4    Borst, P.5
  • 11
    • 1542358189 scopus 로고    scopus 로고
    • Multiple roles for ISWI in transcription, chromosome organization and DNA replication
    • Corona DF, Tamkun JW (2004) Multiple roles for ISWI in transcription, chromosome organization and DNA replication. Biochim Biophys Acta 1677: 113-119
    • (2004) Biochim Biophys Acta , vol.1677 , pp. 113-119
    • Corona, D.F.1    Tamkun, J.W.2
  • 12
    • 13244251108 scopus 로고    scopus 로고
    • Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein
    • DiPaolo C, Kieft R, Cross M, Sabatini R (2005) Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein. Mol Cell 17: 441-451
    • (2005) Mol Cell , vol.17 , pp. 441-451
    • DiPaolo, C.1    Kieft, R.2    Cross, M.3    Sabatini, R.4
  • 13
    • 0029157378 scopus 로고
    • Evolution of the SNF2 family of proteins: Subfamilies with distinct sequences and functions
    • Eisen JA, Sweder KS, Hanawalt PC (1995) Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res 23: 2715-2723
    • (1995) Nucleic Acids Res , vol.23 , pp. 2715-2723
    • Eisen, J.A.1    Sweder, K.S.2    Hanawalt, P.C.3
  • 14
    • 0026537593 scopus 로고
    • Differential expression of two mRNAs from a single gene encoding an HMG1-like DNA binding protein of African trypanosomes
    • Erondu NE, Donelson JE (1992) Differential expression of two mRNAs from a single gene encoding an HMG1-like DNA binding protein of African trypanosomes. Mol Biochem Parasitol 51: 111-118
    • (1992) Mol Biochem Parasitol , vol.51 , pp. 111-118
    • Erondu, N.E.1    Donelson, J.E.2
  • 15
    • 0141922979 scopus 로고    scopus 로고
    • Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI
    • Grune T, Brzeski J, Eberharter A, Clapier CR, Corona DF, Becker PB, Muller CW (2003) Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI. Mol Cell 12: 449-460
    • (2003) Mol Cell , vol.12 , pp. 449-460
    • Grune, T.1    Brzeski, J.2    Eberharter, A.3    Clapier, C.R.4    Corona, D.F.5    Becker, P.B.6    Muller, C.W.7
  • 16
    • 18844462890 scopus 로고    scopus 로고
    • RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei
    • Günzl A, Bruderer T, Laufer G, Schimanski B, Tu LC, Chung HM, Lee PT, Lee MG (2003) RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot Cell 2: 542-551
    • (2003) Eukaryot Cell , vol.2 , pp. 542-551
    • Günzl, A.1    Bruderer, T.2    Laufer, G.3    Schimanski, B.4    Tu, L.C.5    Chung, H.M.6    Lee, P.T.7    Lee, M.G.8
  • 17
    • 0028881923 scopus 로고
    • A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei
    • Horn D, Cross GA (1995) A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei. Cell 83: 555-561
    • (1995) Cell , vol.83 , pp. 555-561
    • Horn, D.1    Cross, G.A.2
  • 18
    • 0031464010 scopus 로고    scopus 로고
    • Position-dependent and promoter-specific regulation of gene expression in Trypanosoma brucei
    • Horn D, Cross GA (1997) Position-dependent and promoter-specific regulation of gene expression in Trypanosoma brucei. EMBO J 16: 7422-7431
    • (1997) EMBO J , vol.16 , pp. 7422-7431
    • Horn, D.1    Cross, G.A.2
  • 19
    • 0036042495 scopus 로고    scopus 로고
    • Histone deacetylases in Trypanosoma brucei: Two are essential and another is required for normal cell cycle progression
    • Ingram AK, Horn D (2002) Histone deacetylases in Trypanosoma brucei: two are essential and another is required for normal cell cycle progression. Mol Micro 45: 89-97
    • (2002) Mol Micro , vol.45 , pp. 89-97
    • Ingram, A.K.1    Horn, D.2
  • 20
    • 0037124117 scopus 로고    scopus 로고
    • Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis
    • LaCount DJ, Barrett B, Donelson JE (2002) Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis. J Biol Chem 277: 17580-17588
    • (2002) J Biol Chem , vol.277 , pp. 17580-17588
    • LaCount, D.J.1    Barrett, B.2    Donelson, J.E.3
  • 22
    • 1542358192 scopus 로고    scopus 로고
    • ISWI complexes in Saccharomyces cerevisiae
    • Mellor J, Morillon A (2004) ISWI complexes in Saccharomyces cerevisiae. Biochim Biophys Acta 1677: 100-112
    • (2004) Biochim Biophys Acta , vol.1677 , pp. 100-112
    • Mellor, J.1    Morillon, A.2
  • 23
    • 14544308853 scopus 로고    scopus 로고
    • Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes
    • Mohrmann L, Verrijzer CP (2005) Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. Biochim Biophys Acta 1681: 59-73
    • (2005) Biochim Biophys Acta , vol.1681 , pp. 59-73
    • Mohrmann, L.1    Verrijzer, C.P.2
  • 24
    • 0038771223 scopus 로고    scopus 로고
    • Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex
    • Moreau JL, Lee M, Mahachi N, Vary J, Mellor J, Tsukiyama T, Goding CR (2003) Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex. Mol Cell 11: 1609-1620
    • (2003) Mol Cell , vol.11 , pp. 1609-1620
    • Moreau, J.L.1    Lee, M.2    Mahachi, N.3    Vary, J.4    Mellor, J.5    Tsukiyama, T.6    Goding, C.R.7
  • 25
    • 0345016384 scopus 로고    scopus 로고
    • Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II
    • Morillon A, Karabetsou N, O'Sullivan J, Kent N, Proudfoot N, Mellor J (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115: 425-435
    • (2003) Cell , vol.115 , pp. 425-435
    • Morillon, A.1    Karabetsou, N.2    O'Sullivan, J.3    Kent, N.4    Proudfoot, N.5    Mellor, J.6
  • 26
    • 0032128354 scopus 로고    scopus 로고
    • In situ analysis of a variant surface glycoprotein expression-site promoter region in Trypanosoma brucei
    • Navarro M, Cross GA (1998) In situ analysis of a variant surface glycoprotein expression-site promoter region in Trypanosoma brucei. Mol Biochem Parasitol 94: 53-66
    • (1998) Mol Biochem Parasitol , vol.94 , pp. 53-66
    • Navarro, M.1    Cross, G.A.2
  • 27
    • 0033561049 scopus 로고    scopus 로고
    • Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites
    • Navarro M, Cross GA, Wirtz E (1999) Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites. EMBO J 18: 2265-2272
    • (1999) EMBO J , vol.18 , pp. 2265-2272
    • Navarro, M.1    Cross, G.A.2    Wirtz, E.3
  • 28
    • 0035856691 scopus 로고    scopus 로고
    • A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei
    • Navarro M, Gull K (2001) A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei. Nature 414: 759-763
    • (2001) Nature , vol.414 , pp. 759-763
    • Navarro, M.1    Gull, K.2
  • 29
    • 4143141923 scopus 로고    scopus 로고
    • Antigenic variation in Trypanosoma brucei: Facts, challenges and mysteries
    • Pays E, Vanhamme L, Perez-Morga D (2004) Antigenic variation in Trypanosoma brucei: facts, challenges and mysteries. Curr Opin Microbiol 7: 369-374
    • (2004) Curr Opin Microbiol , vol.7 , pp. 369-374
    • Pays, E.1    Vanhamme, L.2    Perez-Morga, D.3
  • 30
    • 0029809505 scopus 로고    scopus 로고
    • Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2
    • Richmond E, Peterson CL (1996) Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2. Nucleic Acids Res 24: 3685-3692
    • (1996) Nucleic Acids Res , vol.24 , pp. 3685-3692
    • Richmond, E.1    Peterson, C.L.2
  • 31
    • 0036498581 scopus 로고    scopus 로고
    • Dressed for success: The surface coats of insect-borne protozoan parasites
    • Roditi I, Liniger M (2002) Dressed for success: the surface coats of insect-borne protozoan parasites. Trends Microbiol 10: 128-134
    • (2002) Trends Microbiol , vol.10 , pp. 128-134
    • Roditi, I.1    Liniger, M.2
  • 32
    • 0035851114 scopus 로고    scopus 로고
    • Isolation and characterization of sub-nuclear compartments from Trypanosoma brucei
    • Rout MP, Field MC (2001) Isolation and characterization of sub-nuclear compartments from Trypanosoma brucei. J Biol Chem 276: 38261-38271
    • (2001) J Biol Chem , vol.276 , pp. 38261-38271
    • Rout, M.P.1    Field, M.C.2
  • 33
    • 0028809565 scopus 로고
    • A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei
    • Rudenko G, Blundell PA, Dirks-Mulder A, Kieft R, Borst P (1995) A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei. Cell 83: 547-553
    • (1995) Cell , vol.83 , pp. 547-553
    • Rudenko, G.1    Blundell, P.A.2    Dirks-Mulder, A.3    Kieft, R.4    Borst, P.5
  • 34
    • 0028050668 scopus 로고
    • VSG gene expression site control in insect form Trypanosoma brucei
    • Rudenko G, Blundell PA, Taylor MC, Kieft R, Borst P (1994) VSG gene expression site control in insect form Trypanosoma brucei. EMBO J 13: 5470-5482
    • (1994) EMBO J , vol.13 , pp. 5470-5482
    • Rudenko, G.1    Blundell, P.A.2    Taylor, M.C.3    Kieft, R.4    Borst, P.5
  • 35
    • 0032168225 scopus 로고    scopus 로고
    • Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one
    • Rudenko G, Chaves I, Dirks-Mulder A, Borst P (1998) Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one. Mol Biochem Parasitol 95: 97-109
    • (1998) Mol Biochem Parasitol , vol.95 , pp. 97-109
    • Rudenko, G.1    Chaves, I.2    Dirks-Mulder, A.3    Borst, P.4
  • 37
    • 31044450304 scopus 로고    scopus 로고
    • A greedy promoter controls malarial Var-iations
    • Scherf A (2006) A greedy promoter controls malarial Var-iations. Cell 124: 251-253
    • (2006) Cell , vol.124 , pp. 251-253
    • Scherf, A.1
  • 38
    • 7444270297 scopus 로고    scopus 로고
    • One neuron-one receptor rule in the mouse olfactory system
    • Serizawa S, Miyamichi K, Sakano H (2004) One neuron-one receptor rule in the mouse olfactory system. Trends Genet 20: 648-653
    • (2004) Trends Genet , vol.20 , pp. 648-653
    • Serizawa, S.1    Miyamichi, K.2    Sakano, H.3
  • 39
    • 1842728307 scopus 로고    scopus 로고
    • Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage
    • Sheader K, te Vruchte D, Rudenko G (2004) Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage. J Biol Chem 279: 13363-13374
    • (2004) J Biol Chem , vol.279 , pp. 13363-13374
    • Sheader, K.1    te Vruchte, D.2    Rudenko, G.3
  • 40
    • 20844442483 scopus 로고    scopus 로고
    • Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes
    • Sheader K, Vaughan S, Minchin J, Hughes K, Gull K, Rudenko G (2005) Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proc Natl Acad Sci USA 102: 8716-8721
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8716-8721
    • Sheader, K.1    Vaughan, S.2    Minchin, J.3    Hughes, K.4    Gull, K.5    Rudenko, G.6
  • 42
    • 0842347401 scopus 로고    scopus 로고
    • Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin
    • Strohner R, Nemeth A, Nightingale KP, Grummt I, Becker PB, Langst G (2004) Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol 24: 1791-1798
    • (2004) Mol Cell Biol , vol.24 , pp. 1791-1798
    • Strohner, R.1    Nemeth, A.2    Nightingale, K.P.3    Grummt, I.4    Becker, P.B.5    Langst, G.6
  • 43
    • 0020371206 scopus 로고
    • Bioassay for components regulating eukaryotic gene expression: A chromosomal factor involved in the generation of histone mRNA 3′ termini
    • Stunnenberg HG, Birnstiel ML (1982) Bioassay for components regulating eukaryotic gene expression: a chromosomal factor involved in the generation of histone mRNA 3′ termini. Proc Natl Acad Sci USA 79: 6201-6204
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 6201-6204
    • Stunnenberg, H.G.1    Birnstiel, M.L.2
  • 44
    • 0034106940 scopus 로고    scopus 로고
    • Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei
    • Vanhamme L, Poelvoorde P, Pays A, Tebabi P, Van Xong H, Pays E (2000) Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei. Mol Microbiol 36: 328-340
    • (2000) Mol Microbiol , vol.36 , pp. 328-340
    • Vanhamme, L.1    Poelvoorde, P.2    Pays, A.3    Tebabi, P.4    Van Xong, H.5    Pays, E.6
  • 46
    • 0023045658 scopus 로고
    • Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to domain VII of other eukaryotic 28S rRNAs
    • White TC, Rudenko G, Borst P (1986) Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to domain VII of other eukaryotic 28S rRNAs. Nucleic Acids Res 14: 9471-9489
    • (1986) Nucleic Acids Res , vol.14 , pp. 9471-9489
    • White, T.C.1    Rudenko, G.2    Borst, P.3
  • 47
    • 0036860235 scopus 로고    scopus 로고
    • Targeting of a tetracycline- inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei
    • Wickstead B, Ersfeld K, Gull K (2002) Targeting of a tetracycline- inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei. Mol Biochem Parasitol 125: 211-216
    • (2002) Mol Biochem Parasitol , vol.125 , pp. 211-216
    • Wickstead, B.1    Ersfeld, K.2    Gull, K.3
  • 48
    • 3042616190 scopus 로고    scopus 로고
    • The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes
    • Wickstead B, Ersfeld K, Gull K (2004) The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes. Genome Res 14: 1014-1024
    • (2004) Genome Res , vol.14 , pp. 1014-1024
    • Wickstead, B.1    Ersfeld, K.2    Gull, K.3
  • 49
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz E, Leal S, Ochatt C, Cross GA (1999) A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol 99: 89-101
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.