메뉴 건너뛰기




Volumn 23, Issue 9, 2009, Pages 1063-1076

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

Author keywords

Genome wide ChIP seq; Histone modification; Histone variants; Transcription initiation; Transcription termination; Trypanosoma brucei

Indexed keywords

GUANINE; HISTONE H2A; HISTONE H2B; HISTONE H3; HISTONE H4; RNA POLYMERASE II; DNA DIRECTED DNA POLYMERASE ALPHA; HISTONE; PROTOZOAL PROTEIN;

EID: 65449138352     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1790409     Document Type: Article
Times cited : (291)

References (59)
  • 1
    • 11144327213 scopus 로고    scopus 로고
    • A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei
    • Alibu, V.P., Storm, L., Haile, S., Clayton, C., and Horn, D. 2005. A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei. Mol. Biochem. Parasitol. 139: 75-82.
    • (2005) Mol. Biochem. Parasitol , vol.139 , pp. 75-82
    • Alibu, V.P.1    Storm, L.2    Haile, S.3    Clayton, C.4    Horn, D.5
  • 2
    • 34249026300 scopus 로고    scopus 로고
    • Barski, A., Cuddapah, S., Cui, K., Roh, T.Y., Schones, D.E., Wang, Z., Wei, G., Chepelev, I. and K., Z. 2007. High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
    • Barski, A., Cuddapah, S., Cui, K., Roh, T.Y., Schones, D.E., Wang, Z., Wei, G., Chepelev, I. and K., Z. 2007. High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
  • 3
    • 0029894292 scopus 로고    scopus 로고
    • A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei
    • Bastin, P., Bagherzadeh, A., Matthews, K.R., and Gull, K. 1996. A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei. Mol. Biochem. Parasitol. 77: 235-239.
    • (1996) Mol. Biochem. Parasitol , vol.77 , pp. 235-239
    • Bastin, P.1    Bagherzadeh, A.2    Matthews, K.R.3    Gull, K.4
  • 4
    • 0026052116 scopus 로고    scopus 로고
    • Ben Amar, M.F., Jefferies, D., Pays, A., Bakalara, N., Kendall, G. and E,P. 1991. The actin gene promoter of Trypanosoma brucei. Nucleic Acids Res. 19: 5857-5862.
    • Ben Amar, M.F., Jefferies, D., Pays, A., Bakalara, N., Kendall, G. and E,P. 1991. The actin gene promoter of Trypanosoma brucei. Nucleic Acids Res. 19: 5857-5862.
  • 5
    • 0018601361 scopus 로고
    • Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication
    • Brun, R. and Schonenberger, M. 1979. Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication. Acta Trop. 36: 289-292.
    • (1979) Acta Trop , vol.36 , pp. 289-292
    • Brun, R.1    Schonenberger, M.2
  • 6
    • 0037090528 scopus 로고    scopus 로고
    • Life without transcriptional control? From fly to man and back again
    • Clayton, C.E. 2002. Life without transcriptional control? From fly to man and back again. EMBO J. 21: 1881-1888.
    • (2002) EMBO J , vol.21 , pp. 1881-1888
    • Clayton, C.E.1
  • 7
    • 23344434100 scopus 로고    scopus 로고
    • Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression
    • Das, A., Zhang, Q., Palenchar, J.B., Chatterjee, B., Cross, G.A.M., and Bellofatto, V. 2005. Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol. Cell. Biol. 25: 7314-7322.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 7314-7322
    • Das, A.1    Zhang, Q.2    Palenchar, J.B.3    Chatterjee, B.4    Cross, G.A.M.5    Bellofatto, V.6
  • 8
    • 33747064917 scopus 로고    scopus 로고
    • How does DNA sequence motif discovery work?
    • D'haeseleer, P. 2006. How does DNA sequence motif discovery work? Nat. Biotechnol. 24: 959-961.
    • (2006) Nat. Biotechnol , vol.24 , pp. 959-961
    • D'haeseleer, P.1
  • 9
    • 0033519641 scopus 로고    scopus 로고
    • Structure and ligand of a histone acetyl- transferase bromodomain
    • Dhalluin, C., Carlson, J.E., Zeng, L., He, C., Aggarwal, A.K., and Zhou, M.M. 1999. Structure and ligand of a histone acetyl- transferase bromodomain. Nature 399: 491-496.
    • (1999) Nature , vol.399 , pp. 491-496
    • Dhalluin, C.1    Carlson, J.E.2    Zeng, L.3    He, C.4    Aggarwal, A.K.5    Zhou, M.M.6
  • 11
    • 34547662962 scopus 로고    scopus 로고
    • Trawler: De novo regulatory motif discovery pipeline for chromatin immunoprecipitation
    • Ettwiller, L., Paten, B., Ramialison, M., Birney, E., and Wittbrodt, J. 2007. Trawler: De novo regulatory motif discovery pipeline for chromatin immunoprecipitation. Nat. Methods 4: 563-565.
    • (2007) Nat. Methods , vol.4 , pp. 563-565
    • Ettwiller, L.1    Paten, B.2    Ramialison, M.3    Birney, E.4    Wittbrodt, J.5
  • 12
    • 22844434368 scopus 로고    scopus 로고
    • Homodimeric MyoD preferentially binds tetraplex structures of regulatory sequences of muscle-specific genes
    • Etzioni, S., Yafe, A., Khateb, S., Weisman-Shomer, P., Bengal, E., and Fry, M. 2005. Homodimeric MyoD preferentially binds tetraplex structures of regulatory sequences of muscle-specific genes. J. Biol. Chem. 280: 26805-26812.
    • (2005) J. Biol. Chem , vol.280 , pp. 26805-26812
    • Etzioni, S.1    Yafe, A.2    Khateb, S.3    Weisman-Shomer, P.4    Bengal, E.5    Fry, M.6
  • 13
  • 14
    • 29144531244 scopus 로고    scopus 로고
    • Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning
    • doi: 10.1371/journal.pbio.0030304
    • Guillemette, B., Bataille, A.R., Gevry, N., Adam, M., Blanchette, M., Robert, F., and Gaudreau, L. 2005. Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning. PLoS Biol. 3: e384. doi: 10.1371/journal.pbio.0030304.
    • (2005) PLoS Biol , vol.3
    • Guillemette, B.1    Bataille, A.R.2    Gevry, N.3    Adam, M.4    Blanchette, M.5    Robert, F.6    Gaudreau, L.7
  • 15
    • 0036847620 scopus 로고    scopus 로고
    • Function and selectivity of bromodomains in anchoring chroma- tin-modifying complexes to promoter nucleosomes
    • Hassan, A.H., Prochasson, P., Neely, K.E., Galasinski, S.C., Chandy, M., Carrozza, M.J., and Workman, J.L. 2002. Function and selectivity of bromodomains in anchoring chroma- tin-modifying complexes to promoter nucleosomes. Cell 111: 369-379.
    • (2002) Cell , vol.111 , pp. 369-379
    • Hassan, A.H.1    Prochasson, P.2    Neely, K.E.3    Galasinski, S.C.4    Chandy, M.5    Carrozza, M.J.6    Workman, J.L.7
  • 16
    • 0343526165 scopus 로고    scopus 로고
    • Post-transcriptional control of hsp70 mRNA in Trypanosoma brucei
    • Hausler, T. and Clayton, C. 1996. Post-transcriptional control of hsp70 mRNA in Trypanosoma brucei. Mol. Biochem. Para- sitol. 76: 57-71.
    • (1996) Mol. Biochem. Para- sitol , vol.76 , pp. 57-71
    • Hausler, T.1    Clayton, C.2
  • 17
    • 37249012276 scopus 로고    scopus 로고
    • Nucleosome destabilization in the epigenetic regulation of gene expression
    • Henikoff, S. 2008. Nucleosome destabilization in the epigenetic regulation of gene expression. Nat. Rev. Genet. 9: 15-26.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 15-26
    • Henikoff, S.1
  • 18
    • 0024948840 scopus 로고
    • Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
    • Hirumi, H. and Hirumi, K. 1989. Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J. Parasitol. 75: 985-989.
    • (1989) J. Parasitol , vol.75 , pp. 985-989
    • Hirumi, H.1    Hirumi, K.2
  • 20
    • 33846928449 scopus 로고    scopus 로고
    • G-quadruplexes in promoters throughout the human genome
    • Huppert, J.L. and Balasubramanian, S. 2007. G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res. 35: 406-413.
    • (2007) Nucleic Acids Res , vol.35 , pp. 406-413
    • Huppert, J.L.1    Balasubramanian, S.2
  • 23
    • 34250745886 scopus 로고    scopus 로고
    • Nucleosome stability mediated by histone variants H3.3 and H2A.Z
    • Jin, C. and Felsenfeld, G. 2007. Nucleosome stability mediated by histone variants H3.3 and H2A.Z. Genes & Dev. 21: 1519-1529.
    • (2007) Genes & Dev , vol.21 , pp. 1519-1529
    • Jin, C.1    Felsenfeld, G.2
  • 24
    • 47749130042 scopus 로고    scopus 로고
    • Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes
    • Kawahara, T., Siegel, T.N., Ingram, A.K., Alsford, S., Cross, G.A.M., and Horn, D. 2008. Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes. Mol. Microbiol. 69: 1054-1068.
    • (2008) Mol. Microbiol , vol.69 , pp. 1054-1068
    • Kawahara, T.1    Siegel, T.N.2    Ingram, A.K.3    Alsford, S.4    Cross, G.A.M.5    Horn, D.6
  • 25
    • 0034700156 scopus 로고    scopus 로고
    • A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing
    • Kendall, A., Hull, M.W., Bertrand, E., Good, P.D., Singer, R.H., and Engelke, D.R. 2000. A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing. Proc. Natl. Acad. Sci. 97: 13108-13113.
    • (2000) Proc. Natl. Acad. Sci , vol.97 , pp. 13108-13113
    • Kendall, A.1    Hull, M.W.2    Bertrand, E.3    Good, P.D.4    Singer, R.H.5    Engelke, D.R.6
  • 26
    • 0036226603 scopus 로고    scopus 로고
    • BLAT-The BLAST-like alignment tool
    • Kent, W.J. 2002. BLAT-The BLAST-like alignment tool. Genome Res. 12: 656-664.
    • (2002) Genome Res , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 27
    • 11144355550 scopus 로고    scopus 로고
    • SWRred not shaken, Mixing the histones
    • Korber, P. and Horz, W. 2004. SWRred not shaken, Mixing the histones. Cell 117: 5-7.
    • (2004) Cell , vol.117 , pp. 5-7
    • Korber, P.1    Horz, W.2
  • 28
    • 0030027824 scopus 로고    scopus 로고
    • An RNA polymerase II promoter in the hsp70 locus of Trypanosoma brucei
    • Lee, M.G. 1996. An RNA polymerase II promoter in the hsp70 locus of Trypanosoma brucei. Mol. Cell. Biol. 16: 1220-1230.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 1220-1230
    • Lee, M.G.1
  • 29
    • 33845925394 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation and microarray-based analysis of protein location
    • Lee, T.I., Johnstone, S.E., and Young, R.A. 2006. Chromatin immunoprecipitation and microarray-based analysis of protein location. Nat. Protocols 1: 729-748.
    • (2006) Nat. Protocols , vol.1 , pp. 729-748
    • Lee, T.I.1    Johnstone, S.E.2    Young, R.A.3
  • 30
    • 0142247085 scopus 로고    scopus 로고
    • trans and cis splicing in trypanosomatids: Mechanism, factors, and regulation
    • Liang, X.H., Haritan, A., Uliel, S., and Michaeli, S. 2003. trans and cis splicing in trypanosomatids: Mechanism, factors, and regulation. Eukaryot. Cell 2: 830-840.
    • (2003) Eukaryot. Cell , vol.2 , pp. 830-840
    • Liang, X.H.1    Haritan, A.2    Uliel, S.3    Michaeli, S.4
  • 31
    • 12344257200 scopus 로고    scopus 로고
    • A variant histone H3 is enriched at telomeres in Trypanosoma brucei
    • Lowell, J.E. and Cross, G.A.M. 2004. A variant histone H3 is enriched at telomeres in Trypanosoma brucei. J. Cell Sci. 117: 5937-5947.
    • (2004) J. Cell Sci , vol.117 , pp. 5937-5947
    • Lowell, J.E.1    Cross, G.A.M.2
  • 32
    • 30544449686 scopus 로고    scopus 로고
    • Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei
    • Lowell, J.E., Kaiser, F., Janzen, C.J., and Cross, G.A.M. 2005. Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei. J. Cell Sci. 118: 5721-5730.
    • (2005) J. Cell Sci , vol.118 , pp. 5721-5730
    • Lowell, J.E.1    Kaiser, F.2    Janzen, C.J.3    Cross, G.A.M.4
  • 34
    • 40049098866 scopus 로고    scopus 로고
    • Trypano- some H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation
    • Mandava, V., Janzen, C.J., and Cross, G.A.M. 2008. Trypano- some H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation. Biochem. Biophys. Res. Commun. 368: 846-851.
    • (2008) Biochem. Biophys. Res. Commun , vol.368 , pp. 846-851
    • Mandava, V.1    Janzen, C.J.2    Cross, G.A.M.3
  • 35
    • 0032146615 scopus 로고    scopus 로고
    • Physical and transcriptional analysis of the Trypanosoma brucei genome reveals a typical eukaryotic arrangement with close interspersionof RNA polymerase II- and III-transcribed genes
    • Marchetti, M.A., Tschudi, C., Silva, E., and Ullu, E. 1998. Physical and transcriptional analysis of the Trypanosoma brucei genome reveals a typical eukaryotic arrangement with close interspersionof RNA polymerase II- and III-transcribed genes. Nucleic Acids Res. 26: 3591-3598.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3591-3598
    • Marchetti, M.A.1    Tschudi, C.2    Silva, E.3    Ullu, E.4
  • 36
    • 0026087251 scopus 로고
    • Participation of the TATA factor in transcription of the yeast U6 gene by RNA polymerase C
    • Margottin, F., Dujardin, G., Gerard, M., Egly, J.M., Huet, J., and Sentenac, A. 1991. Participation of the TATA factor in transcription of the yeast U6 gene by RNA polymerase C. Science 251: 424-426.
    • (1991) Science , vol.251 , pp. 424-426
    • Margottin, F.1    Dujardin, G.2    Gerard, M.3    Egly, J.M.4    Huet, J.5    Sentenac, A.6
  • 37
    • 0038730932 scopus 로고    scopus 로고
    • Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region
    • Martinez-Calvillo, S., Yan, S., Nguyen, D., Fox, M., Stuart, K., and Myler, P.J. 2003. Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region. Mol. Cell 11: 1291-1299.
    • (2003) Mol. Cell , vol.11 , pp. 1291-1299
    • Martinez-Calvillo, S.1    Yan, S.2    Nguyen, D.3    Fox, M.4    Stuart, K.5    Myler, P.J.6
  • 38
    • 0031755130 scopus 로고    scopus 로고
    • Testing promoter activity in the trypanosome genome: Isolation of a metacyclic-type VSG promoter, and unexpected insights into RNA polymerase II transcription
    • McAndrew, M., Graham, S., Hartmann, C., and Clayton, C. 1998. Testing promoter activity in the trypanosome genome: Isolation of a metacyclic-type VSG promoter, and unexpected insights into RNA polymerase II transcription. Exp. Parasitol. 90: 65-76.
    • (1998) Exp. Parasitol , vol.90 , pp. 65-76
    • McAndrew, M.1    Graham, S.2    Hartmann, C.3    Clayton, C.4
  • 39
    • 27144510368 scopus 로고    scopus 로고
    • Genome-scale profiling of histone H3.3 replacement patterns
    • Mito, Y., Henikoff, J.G., and Henikoff, S. 2005. Genome-scale profiling of histone H3.3 replacement patterns. Nat. Genet. 37: 1090-1097.
    • (2005) Nat. Genet , vol.37 , pp. 1090-1097
    • Mito, Y.1    Henikoff, J.G.2    Henikoff, S.3
  • 40
    • 0028001399 scopus 로고
    • Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes
    • Nakaar, V., Dare, A.O., Hong, D., Ullu, E., and Tschudi, C. 1994. Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes. Mol. Cell. Biol. 14: 6736-6742.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 6736-6742
    • Nakaar, V.1    Dare, A.O.2    Hong, D.3    Ullu, E.4    Tschudi, C.5
  • 41
    • 0343417075 scopus 로고    scopus 로고
    • Structure of the Trypanosoma brucei U6 snRNA gene promoter
    • Nakaar, V., Gunzl, A., Ullu, E., and Tschudi, C. 1997. Structure of the Trypanosoma brucei U6 snRNA gene promoter. Mol. Biochem. Parasitol. 88: 13-23.
    • (1997) Mol. Biochem. Parasitol , vol.88 , pp. 13-23
    • Nakaar, V.1    Gunzl, A.2    Ullu, E.3    Tschudi, C.4
  • 42
    • 33646912186 scopus 로고    scopus 로고
    • A role for TFIIIC transcription factor complex in genome organization
    • Noma, K., Cam, H.P., Maraia, R.J., and Grewal, S.I. 2006. A role for TFIIIC transcription factor complex in genome organization. Cell 125: 859-872.
    • (2006) Cell , vol.125 , pp. 859-872
    • Noma, K.1    Cam, H.P.2    Maraia, R.J.3    Grewal, S.I.4
  • 43
    • 28044439662 scopus 로고    scopus 로고
    • A vector series for rapid PCR-mediated C-terminal in situ tagging of Trypanosoma brucei genes
    • Oberholzer, M., Morand, S., Kunz, S., and Seebeck, T. 2006. A vector series for rapid PCR-mediated C-terminal in situ tagging of Trypanosoma brucei genes. Mol. Biochem. Para- sitol. 145: 117-120.
    • (2006) Mol. Biochem. Para- sitol , vol.145 , pp. 117-120
    • Oberholzer, M.1    Morand, S.2    Kunz, S.3    Seebeck, T.4
  • 44
    • 44649193767 scopus 로고    scopus 로고
    • MYSTs mark chromatin for chromosomal functions
    • Pillus, L. 2008. MYSTs mark chromatin for chromosomal functions. Curr. Opin. Cell Biol. 20: 326-333.
    • (2008) Curr. Opin. Cell Biol , vol.20 , pp. 326-333
    • Pillus, L.1
  • 46
    • 47049084288 scopus 로고    scopus 로고
    • Histone acetylation and methylation at sites initiating divergent polycistronic transcription in Trypanosoma cruzi
    • Respuela, P., Ferella, M., Rada-Iglesias, A., and Aslund, L. 2008. Histone acetylation and methylation at sites initiating divergent polycistronic transcription in Trypanosoma cruzi. J. Biol. Chem. 283: 15884-15892.
    • (2008) J. Biol. Chem , vol.283 , pp. 15884-15892
    • Respuela, P.1    Ferella, M.2    Rada-Iglesias, A.3    Aslund, L.4
  • 47
    • 36348958426 scopus 로고    scopus 로고
    • CRE recombi-nase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei
    • Scahill, M.D., Pastar, I., and Cross, G.A.M. 2008. CRE recombi-nase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei. Mol. Biochem. Parasitol. 157: 73-82.
    • (2008) Mol. Biochem. Parasitol , vol.157 , pp. 73-82
    • Scahill, M.D.1    Pastar, I.2    Cross, G.A.M.3
  • 48
    • 23344448980 scopus 로고    scopus 로고
    • Characterization of a multisubunit transcription factor complex essential for spliced-leader RNA gene transcription in Trypanosoma brucei
    • Schimanski, B., Nguyen, T.N., and Gunzl, A. 2005. Characterization of a multisubunit transcription factor complex essential for spliced-leader RNA gene transcription in Trypanosoma brucei. Mol. Cell. Biol. 25: 7303-7313.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 7303-7313
    • Schimanski, B.1    Nguyen, T.N.2    Gunzl, A.3
  • 50
    • 33748698658 scopus 로고    scopus 로고
    • SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae
    • Shia, W.J., Li, B., and Workman, J.L. 2006. SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae. Genes & Dev. 20: 2507-2512.
    • (2006) Genes & Dev , vol.20 , pp. 2507-2512
    • Shia, W.J.1    Li, B.2    Workman, J.L.3
  • 51
    • 44649139771 scopus 로고    scopus 로고
    • Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation
    • Shilatifard, A. 2008. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr. Opin. Cell Biol. 20: 341-348.
    • (2008) Curr. Opin. Cell Biol , vol.20 , pp. 341-348
    • Shilatifard, A.1
  • 52
    • 38449103829 scopus 로고    scopus 로고
    • Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei
    • Siegel, T.N., Kawahara, T., Degrasse, J.A., Janzen, C.J., Horn, D., and Cross, G.A.M. 2008a. Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei. Mol. Microbiol. 67: 762-771.
    • (2008) Mol. Microbiol , vol.67 , pp. 762-771
    • Siegel, T.N.1    Kawahara, T.2    Degrasse, J.A.3    Janzen, C.J.4    Horn, D.5    Cross, G.A.M.6
  • 53
    • 50049135930 scopus 로고    scopus 로고
    • Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging
    • Siegel, T.N., Hekstra, D.R., and Cross, G.A.M. 2008b. Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging. Mol. Biochem. Parasitol. 160: 171-174.
    • (2008) Mol. Biochem. Parasitol , vol.160 , pp. 171-174
    • Siegel, T.N.1    Hekstra, D.R.2    Cross, G.A.M.3
  • 55
    • 45149134017 scopus 로고    scopus 로고
    • G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA poly- merase II
    • Tornaletti, S., Park-Snyder, S., and Hanawalt, P.C. 2008. G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA poly- merase II. J. Biol. Chem. 283: 12756-12762.
    • (2008) J. Biol. Chem , vol.283 , pp. 12756-12762
    • Tornaletti, S.1    Park-Snyder, S.2    Hanawalt, P.C.3
  • 56
    • 0017142124 scopus 로고
    • Chromosomal subunits in active genes have an altered conformation
    • Weintraub, H. and Groudine, M. 1976. Chromosomal subunits in active genes have an altered conformation. Science 193: 848-856.
    • (1976) Science , vol.193 , pp. 848-856
    • Weintraub, H.1    Groudine, M.2
  • 57
    • 17444386662 scopus 로고    scopus 로고
    • The bromodomain: A chromatin- targeting module?
    • Winston, F. and Allis, C.D. 1999. The bromodomain: A chromatin- targeting module? Nat. Struct. Biol. 6: 601-604.
    • (1999) Nat. Struct. Biol , vol.6 , pp. 601-604
    • Winston, F.1    Allis, C.D.2
  • 58
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz, E., Leal, S., Ochatt, C., and Cross, G.A.M. 1999. A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol. Biochem. Parasitol. 99: 89-101.
    • (1999) Mol. Biochem. Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.M.4
  • 59
    • 26844489856 scopus 로고    scopus 로고
    • Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss
    • Zhang, H., Roberts, D.N., and Cairns, B.R. 2005. Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell 123: 219-231.
    • (2005) Cell , vol.123 , pp. 219-231
    • Zhang, H.1    Roberts, D.N.2    Cairns, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.