Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Barrett, James P ^a   Costello, Derek A ^a   O'Sullivan, Joan ^a   Cowley, Thelma R ^a   Lynch, Marina A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Age; Bone marrow derived macrophages; Inflammatory cytokines; Interferon (IFN ); Lipopolysaccharide (LPS); Macrophage phenotypes

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR 1; HIGH MOBILITY GROUP B1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MESSENGER RNA; NOS2 PROTEIN, RAT; TUMOR NECROSIS FACTOR;

AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BONE MARROW DERIVED MACROPHAGE; BRAIN FUNCTION; CELL ACTIVATION; CELL INFILTRATION; CONTROLLED STUDY; IN VITRO STUDY; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MICROENVIRONMENT; MICROGLIA; NONHUMAN; PROTEIN EXPRESSION; RAT; STIMULUS RESPONSE; UPREGULATION; AGE; AGING; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; MACROPHAGE; METABOLISM; NEWBORN; WISTAR RAT;

AGE FACTORS; AGING; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84927670623     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0287-7     Document Type: Article

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