Activation of murine macrophages

Current Protocols in Immunology

Volumn , Issue SUPPL. 83, 2008, Pages

  Mosser, David M ^a   Zhang, Xia ^a  

^a Bldg 142   (United States)

Author keywords

IL 10; IL 12; IL 4; Immune complexes; Interferon ; Lipopolysaccharide; Mannose receptor; Toll like receptors; Tumor necrosis factor

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; CELL POPULATION; CELLULAR IMMUNITY; CYTOKINE RELEASE; CYTOTOXICITY; EFFECTOR CELL; EXPERIMENTAL DESIGN; HOST RESISTANCE; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; UPREGULATION; WOUND HEALING;

ANIMALS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-13; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE;

EID: 58849101761     PISSN: 19343671     EISSN: 1934368X     Source Type: Journal    
DOI: 10.1002/0471142735.im1402s83     Document Type: Review

References (15)

1. Celada, A. and Nathan, C. 1994. Macrophage activation revisited. Immunol. Today 15:100-102.
2. Cohn, Z. 1978. The activation of mononuclear phagocytes: Fact, fancy, and future. J. Immunol. 121:813-816.
3. Edwards, J.P., Zhang, X., Frauwirth, K.A., and Mosser, D.M. 2006. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 80:1298-1307.
4. Gerber, J.S. and Mosser, D.M. 2001. Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors. J. Immunol. 166:6861-6868.
5. Gordon, S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35.
6. Gordon, S. 2007. The macrophage: Past, present, and future. Eur. J. Immunol. 37:S9-S17.
7. Hesse, M., Modolell, M., LaFlamme, A.C., Schito, M., Fuentes, J.M., Cheever, A.W., Pearce, E.J., and Wynn, T.A. 2001. Differential regulation of nitroxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo. Gramulomatous pathology is shaped by the pattern of L-arginine metabolism. J. Immunol. 167:6533-6544.
8. Hölscher, C., Arendse, B., Schwegmann, A., Myburgh, E., and Brombacher, F. 2006. Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice. J Immunol. 176:1115-1121.
9. Markaness, G.B. 1962. Cellular resistance to infection. J. Exp. Med. 116:381-406.
10. Mosser, D.M. 2003. Themany faces of macrophage activation. J. Leukoc. Biol. 73:209-212.
11. Raes, G., De Baetselier, P., Noël, W., Beschin, A., Brombacher, F., and Hassanzadeh, G.G. 2002. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J. Leukoc. Biol. 71:597-602.
12. Sica, A., Allavena, P., and Mantovani, A. 2008. Cancer related inflammation: The macrophage connection. Cancer Lett. 267:204-215.
13. Stein, M., Keshav, S., Harris, N., and Gordon, S. 1992. Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation. J. Exp. Med. 176:287-292.
14. Wynn, T.A. 2003. IL-13 effector functions. Annu. Rev. Immunol. 21:425-456.
15. Zhang, X. and Mosser, D.M. 2008. Macrophage activation by endogenous danger signals. J. Pathol. 214:161-178.