CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients

Journal of Immunology

Volumn 194, Issue 8, 2015, Pages 3768-3777

  Kaltenmeier, Christof ^a,b   Gawanbacht, Ali ^a   Beyer, Thamara ^a   Lindner, Stefanie ^a   Trzaska, Timo ^a   Van Der Merwe, Johannes Andreas ^a   Härter, Georg ^a   Gruyner, Beate ^a   Fabricius, Dorit ^a   Lotfi, Ramin ^a,c   Schwarz, Klaus ^a,c   Schütz, Catharina ^a   Hönig, Manfred ^a   Schulz, Ansgar ^a   Kern, Peter ^a   Bommer, Martin ^a   Schrezenmeier, Hubert ^a,c   Kirchhoff, Frank ^a   Jahrsdörfer, Bernd ^a,c  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c German Red Cross Blood Transfusion Service Baden Württemberg Hessen and University Hospital Ulm   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD40 LIGAND; CD5 ANTIGEN; CD86 ANTIGEN; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 21; LEUKOSIALIN; NEF PROTEIN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG; CD40 ANTIGEN; GRANZYME; GZMB PROTEIN, HUMAN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IN VIVO STUDY; MALE; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; GENE EXPRESSION REGULATION; GENETICS; HELPER CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MUTATION; PATHOLOGY; VACCINATION;

AIDS VACCINES; ANTIGENS, CD40; B-LYMPHOCYTES, REGULATORY; CD40 LIGAND; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANZYMES; HIV INFECTIONS; HUMANS; I-KAPPA B KINASE; INTERLEUKINS; MALE; MUTATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; VACCINATION;

EID: 84927586722     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402568     Document Type: Article

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