메뉴 건너뛰기




Volumn 40, Issue 7, 2010, Pages 2060-2069

CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B

Author keywords

Apoptosis; Autoimmunity; B cells; BCR; Immune regulation

Indexed keywords

CD5 ANTIGEN; GRANZYME B; INTERLEUKIN 21; GRANZYME; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN DERIVATIVE; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 77954122576     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940113     Document Type: Article
Times cited : (52)

References (51)
  • 1
    • 0036217975 scopus 로고    scopus 로고
    • Origins and functions of B-1 cells with notes on the role of CD5
    • Berland, R. and Wortis, H. H., Origins and functions of B-1 cells with notes on the role of CD5. Annu. Rev. Immunol. 2002. 20: 253-300.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 253-300
    • Berland, R.1    Wortis, H.H.2
  • 2
    • 33746503135 scopus 로고    scopus 로고
    • Role of B-1a cells in autoimmunity
    • Duan, B. and Morel, L., Role of B-1a cells in autoimmunity. Autoimmun. Rev. 2006. 5: 403-408.
    • (2006) Autoimmun. Rev. , vol.5 , pp. 403-408
    • Duan, B.1    Morel, L.2
  • 4
    • 0024147110 scopus 로고
    • Normal, autoimmune, and malignant CD5 + B cells: The Ly-1 B lineage?
    • Hayakawa, K. and Hardy, R. R., Normal, autoimmune, and malignant CD5 + B cells: the Ly-1 B lineage? Annu. Rev. Immunol. 1988. 6: 197-218.
    • (1988) Annu. Rev. Immunol. , vol.6 , pp. 197-218
    • Hayakawa, K.1    Hardy, R.R.2
  • 5
    • 0023127468 scopus 로고
    • + B-cell subset
    • Casali, P., Burastero, S. E., Nakamura, M., Inghirami, G. and Notkins, A. L., Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset. Science 1987. 236: 77-81. (Pubitemid 17056816)
    • (1987) Science , vol.236 , Issue.4797 , pp. 77-81
    • Casali, P.1    Burastero, S.E.2    Nakamura, M.3
  • 6
    • 36148945270 scopus 로고    scopus 로고
    • The paradox of CD5-expressing B cells in systemic lupus erythematosus
    • Youinou, P. and Renaudineau, Y., The paradox of CD5-expressing B cells in systemic lupus erythematosus. Autoimmun. Rev. 2007. 7: 149-154.
    • (2007) Autoimmun. Rev. , vol.7 , pp. 149-154
    • Youinou, P.1    Renaudineau, Y.2
  • 7
    • 43049156086 scopus 로고    scopus 로고
    • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
    • Yanaba, K., Bouaziz, J. D., Haas, K. M., Poe, J. C., Fujimoto, M. and Tedder, T. F., A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 2008. 28: 639-650.
    • (2008) Immunity , vol.28 , pp. 639-650
    • Yanaba, K.1    Bouaziz, J.D.2    Haas, K.M.3    Poe, J.C.4    Fujimoto, M.5    Tedder, T.F.6
  • 8
    • 34547786479 scopus 로고    scopus 로고
    • Development of psoriasis after B cell depletion with rituximab
    • Dass, S., Vital, E. M. and Emery, P., Development of psoriasis after B cell depletion with rituximab. Arthritis Rheum. 2007. 56: 2715-2718.
    • (2007) Arthritis Rheum. , vol.56 , pp. 2715-2718
    • Dass, S.1    Vital, E.M.2    Emery, P.3
  • 9
    • 0034597789 scopus 로고    scopus 로고
    • Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
    • Parrish-Novak, J., Dillon, S. R., Nelson, A., Hammond, A., Sprecher, C., Gross, J. A., Johnston, J. et al., Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000. 408: 57-63.
    • (2000) Nature , vol.408 , pp. 57-63
    • Parrish-Novak, J.1    Dillon, S.R.2    Nelson, A.3    Hammond, A.4    Sprecher, C.5    Gross, J.A.6    Johnston, J.7
  • 10
    • 42649134105 scopus 로고    scopus 로고
    • Interleukin-21: Basic biology and implications for cancer and autoimmunity
    • Spolski, R. and Leonard, W. J., Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 2008. 26: 57-79.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 57-79
    • Spolski, R.1    Leonard, W.J.2
  • 11
    • 45449104408 scopus 로고    scopus 로고
    • The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer
    • Spolski, R. and Leonard, W. J., The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer. Curr. Opin. Immunol. 2008. 20: 295-301.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 295-301
    • Spolski, R.1    Leonard, W.J.2
  • 12
    • 0346995205 scopus 로고    scopus 로고
    • IL-21: A novel IL-2-family lymphokine that modulates B, T, and natural killer cell responses
    • Habib, T., Nelson, A. and Kaushansky, K., IL-21: a novel IL-2-family lymphokine that modulates B, T, and natural killer cell responses. J. Allergy Clin. Immunol. 2003. 112: 1033-1045.
    • (2003) J. Allergy Clin. Immunol. , vol.112 , pp. 1033-1045
    • Habib, T.1    Nelson, A.2    Kaushansky, K.3
  • 13
    • 47249097068 scopus 로고    scopus 로고
    • The role of IL-21 in regulating B-cell function in health and disease
    • Ettinger, R., Kuchen, S. and Lipsky, P. E., The role of IL-21 in regulating B-cell function in health and disease. Immunol. Rev. 2008. 223: 60-86.
    • (2008) Immunol. Rev. , vol.223 , pp. 60-86
    • Ettinger, R.1    Kuchen, S.2    Lipsky, P.E.3
  • 14
    • 56749183893 scopus 로고    scopus 로고
    • Interleukin 21 as a target of intervention in autoimmune disease
    • Ettinger, R., Kuchen, S. and Lipsky, P. E., Interleukin 21 as a target of intervention in autoimmune disease. Ann. Rheum. Dis. 2008. 67: iii83-iii86.
    • (2008) Ann. Rheum. Dis. , vol.67
    • Ettinger, R.1    Kuchen, S.2    Lipsky, P.E.3
  • 15
    • 68149099548 scopus 로고    scopus 로고
    • Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21
    • Hagn, M., Schwesinger, E., Ebel, V., Sontheimer, K., Maier, J., Beyer, T., Syrovets, T. et al., Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. J. Immunol. 2009 183: 1838-1845.
    • (2009) J. Immunol. , vol.183 , pp. 1838-1845
    • Hagn, M.1    Schwesinger, E.2    Ebel, V.3    Sontheimer, K.4    Maier, J.5    Beyer, T.6    Syrovets, T.7
  • 16
    • 0038725690 scopus 로고    scopus 로고
    • The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal
    • Lieberman, J., The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nat. Rev. Immunol. 2003. 3: 361-370.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 361-370
    • Lieberman, J.1
  • 17
    • 77949529017 scopus 로고    scopus 로고
    • Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion
    • Jahrsdörfer, B., Vollmer, A., Blackwell, S. E., Maier, J., Sontheimer, K., Beyer, T., Mandel, B. et al., Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion. Blood 2010. 115: 1156-1165.
    • (2010) Blood , vol.115 , pp. 1156-1165
    • Jahrsdörfer, B.1    Vollmer, A.2    Blackwell, S.E.3    Maier, J.4    Sontheimer, K.5    Beyer, T.6    Mandel, B.7
  • 18
    • 33750626239 scopus 로고    scopus 로고
    • B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation
    • Jahrsdörfer, B., Blackwell, S. E., Wooldridge, J. E., Huang, J., Andreski, M. W., Jacobus, L. S., Taylor, C. M. and Weiner, G. J., B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation. Blood 2006. 108: 2712-2719.
    • (2006) Blood , vol.108 , pp. 2712-2719
    • Jahrsdörfer, B.1    Blackwell, S.E.2    Wooldridge, J.E.3    Huang, J.4    Andreski, M.W.5    Jacobus, L.S.6    Taylor, C.M.7    Weiner, G.J.8
  • 19
    • 33749315904 scopus 로고    scopus 로고
    • Granzyme B, a novel mediator of allergic inflammation: Its induction and release in blood basophils and human asthma
    • Tschopp, C. M., Spiegl, N., Didichenko, S., Lutmann, W., Julius, P., Virchow, J. C., Hack, C. E. and Dahinden, C. A., Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma. Blood 2006. 108: 2290-2299.
    • (2006) Blood , vol.108 , pp. 2290-2299
    • Tschopp, C.M.1    Spiegl, N.2    Didichenko, S.3    Lutmann, W.4    Julius, P.5    Virchow, J.C.6    Hack, C.E.7    Dahinden, C.A.8
  • 20
    • 34248589178 scopus 로고    scopus 로고
    • Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation
    • Strik, M. C., de Koning, P. J., Kleijmeer, M. J., Bladergroen, B. A., Wolbink, A. M., Griffith, J. M. et al., Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation. Mol. Immunol. 2007. 44: 3462-3472.
    • (2007) Mol. Immunol. , vol.44 , pp. 3462-3472
    • Strik, M.C.1    De Koning, P.J.2    Kleijmeer, M.J.3    Bladergroen, B.A.4    Wolbink, A.M.5    Griffith, J.M.6
  • 21
    • 0028875927 scopus 로고
    • Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor
    • Berthou, C., Marolleau, J. P., Lafaurie, C., Soulie, A., Dal Cortivo, L., Bourge, J. F., Benbunan, M. and Sasportes, M., Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor. Blood 1995. 86: 3500-3506.
    • (1995) Blood , vol.86 , pp. 3500-3506
    • Berthou, C.1    Marolleau, J.P.2    Lafaurie, C.3    Soulie, A.4    Dal Cortivo, L.5    Bourge, J.F.6    Benbunan, M.7    Sasportes, M.8
  • 22
    • 33747144028 scopus 로고    scopus 로고
    • Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells
    • Devadas, S., Das, J., Liu, C., Zhang, L., Roberts, A. I., Pan, Z., Moore, P. A. et al., Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells. Immunity 2006. 25: 237-247.
    • (2006) Immunity , vol.25 , pp. 237-247
    • Devadas, S.1    Das, J.2    Liu, C.3    Zhang, L.4    Roberts, A.I.5    Pan, Z.6    Moore, P.A.7
  • 23
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek, D. C., Lu, L. F., Quezada, S. A., Sakaguchi, S. and Noelle, R. J., Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J. Immunol. 2005. 174: 1783-1786.
    • (2005) J. Immunol. , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 25
    • 0033588955 scopus 로고    scopus 로고
    • Cleavage by granzyme B is strongly predictive of autoantigen status: Implications for initiation of autoimmunity
    • Casciola-Rosen, L., Andrade, F., Ulanet, D., Wong, W. B. and Rosen, A., Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity. J. Exp. Med. 1999. 190: 815-826.
    • (1999) J. Exp. Med. , vol.190 , pp. 815-826
    • Casciola-Rosen, L.1    Andrade, F.2    Ulanet, D.3    Wong, W.B.4    Rosen, A.5
  • 26
    • 0032917731 scopus 로고    scopus 로고
    • Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease
    • Rosen, A. and Casciola-Rosen, L., Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease. Cell Death Differ. 1999. 6: 6-12. (Pubitemid 29051849)
    • (1999) Cell Death and Differentiation , vol.6 , Issue.1 , pp. 6-12
    • Rosen, A.1    Casciola-Rosen, L.2
  • 28
    • 77949529810 scopus 로고    scopus 로고
    • Granzyme B cleavage of autoantigens in autoimmunity
    • Darrah, E. and Rosen, A., Granzyme B cleavage of autoantigens in autoimmunity. Cell Death Differ. 2010. 17: 624-632.
    • (2010) Cell Death Differ. , vol.17 , pp. 624-632
    • Darrah, E.1    Rosen, A.2
  • 30
    • 0027136685 scopus 로고
    • Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes
    • Froelich, C. J., Zhang, X., Turbov, J., Hudig, D., Winkler, U. and Hanna, W. L., Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes. J. Immunol. 1993. 151: 7161-7171. (Pubitemid 24001090)
    • (1993) Journal of Immunology , vol.151 , Issue.12 , pp. 7161-7171
    • Froelich, C.J.1    Zhang, X.2    Turbov, J.3    Hudig, D.4    Winkler, U.5    Hanna, W.L.6
  • 31
    • 33746255647 scopus 로고    scopus 로고
    • Extracellular granzymes: Current perspectives
    • Buzza, M. S. and Bird, P. I., Extracellular granzymes: current perspectives. Biol. Chem. 2006. 387: 827-837.
    • (2006) Biol. Chem. , vol.387 , pp. 827-837
    • Buzza, M.S.1    Bird, P.I.2
  • 32
    • 42149142424 scopus 로고    scopus 로고
    • Non-apoptotic functions of granzymes
    • Romero, V. and Andrade, F., Non-apoptotic functions of granzymes. Tissue Antigens 2008. 71: 409-416.
    • (2008) Tissue Antigens , vol.71 , pp. 409-416
    • Romero, V.1    Andrade, F.2
  • 34
    • 0032055984 scopus 로고    scopus 로고
    • Extracellular granzymes a and B in humans: Detection of native species during CTL responses in vitro and in vivo
    • Spaeny-Dekking, E. H., Hanna, W. L., Wolbink, A. M., Wever, P. C., Kummer, A. J., Swaak, A. J. et al., Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo. J. Immunol. 1998. 160: 3610-3616.
    • (1998) J. Immunol. , vol.160 , pp. 3610-3616
    • Spaeny-Dekking, E.H.1    Hanna, W.L.2    Wolbink, A.M.3    Wever, P.C.4    Kummer, A.J.5    Swaak, A.J.6
  • 35
    • 35748930247 scopus 로고    scopus 로고
    • Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus
    • Bubier, J. A., Bennett, S. M., Sproule, T. J., Lyons, B. L., Olland, S., Young, D. A. and Roopenian, D. C., Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus. Ann. NY Acad. Sci. 2007. 1110: 590-601.
    • (2007) Ann. NY Acad. Sci. , vol.1110 , pp. 590-601
    • Bubier, J.A.1    Bennett, S.M.2    Sproule, T.J.3    Lyons, B.L.4    Olland, S.5    Young, D.A.6    Roopenian, D.C.7
  • 38
    • 20744451720 scopus 로고    scopus 로고
    • Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus
    • Graham, K. L., Thibault, D. L., Steinman, J. B., Okeke, L., Kao, P. N. and Utz, P. J., Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus. Arthritis Rheum. 2005. 52: 1684-1693.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1684-1693
    • Graham, K.L.1    Thibault, D.L.2    Steinman, J.B.3    Okeke, L.4    Kao, P.N.5    Utz, P.J.6
  • 39
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • Sims, G. P., Ettinger, R., Shirota, Y., Yarboro, C. H., Illei, G. G. and Lipsky, P. E., Identification and characterization of circulating human transitional B cells. Blood 2005. 105: 4390-4398.
    • (2005) Blood , vol.105 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 40
    • 10744233370 scopus 로고    scopus 로고
    • Granzyme B leakage-induced cell death: A new type of activation-induced natural killer cell death
    • Ida, H., Nakashima, T., Kedersha, N. L., Yamasaki, S., Huang, M., Izumi, Y.,Miyashita, T. et al., Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. Eur. J. Immunol. 2003. 33: 3284-3292.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 3284-3292
    • Ida, H.1    Nakashima, T.2    Kedersha, N.L.3    Yamasaki, S.4    Huang, M.5    Izumi, Y.6    Miyashita, T.7
  • 41
    • 33847342813 scopus 로고    scopus 로고
    • IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells
    • Ettinger, R., Sims, G. P., Robbins, R., Withers, D., Fischer, R. T., Grammer, A. C., Kuchen, S. and Lipsky, P. E., IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J. Immunol. 2007. 178: 2872-2882.
    • (2007) J. Immunol. , vol.178 , pp. 2872-2882
    • Ettinger, R.1    Sims, G.P.2    Robbins, R.3    Withers, D.4    Fischer, R.T.5    Grammer, A.C.6    Kuchen, S.7    Lipsky, P.E.8
  • 43
    • 61649102448 scopus 로고    scopus 로고
    • Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs
    • Van Damme, P., Maurer-Stroh, S., Plasman, K., Van Durme, J., Colaert, N., Timmerman, E., Debock, P. J. et al., Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs. Mol. Cell. Proteomics 2009 8: 258-272.
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 258-272
    • Van Damme, P.1    Maurer-Stroh, S.2    Plasman, K.3    Van Durme, J.4    Colaert, N.5    Timmerman, E.6    Debock, P.J.7
  • 44
    • 67649217469 scopus 로고    scopus 로고
    • IL-21 is required to control chronic viral infection
    • Elsaesser, H., Sauer, K. and Brooks, D. G., IL-21 is required to control chronic viral infection. Science 2009. 324: 1569-1572.
    • (2009) Science , vol.324 , pp. 1569-1572
    • Elsaesser, H.1    Sauer, K.2    Brooks, D.G.3
  • 45
    • 67649171872 scopus 로고    scopus 로고
    • Immunology. A chronic need for IL-21
    • Johnson, L. D. and Jameson, S. C., Immunology. A chronic need for IL-21. Science 2009. 324: 1525-1526.
    • (2009) Science , vol.324 , pp. 1525-1526
    • Johnson, L.D.1    Jameson, S.C.2
  • 46
    • 67649203681 scopus 로고    scopus 로고
    • A vital role for interleukin-21 in the control of a chronic viral infection
    • Yi, J. S., Du, M. and Zajac, A. J., A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009. 324: 1572-1576.
    • (2009) Science , vol.324 , pp. 1572-1576
    • Yi, J.S.1    Du, M.2    Zajac, A.J.3
  • 48
    • 33947215987 scopus 로고    scopus 로고
    • IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression
    • Herber, D., Brown, T. P., Liang, S., Young, D. A., Collins, M. and Dunussi-Joannopoulos, K., IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J. Immunol. 2007. 178: 3822-3830. (Pubitemid 46417651)
    • (2007) Journal of Immunology , vol.178 , Issue.6 , pp. 3822-3830
    • Herber, D.1    Brown, T.P.2    Liang, S.3    Young, D.A.4    Collins, M.5    Dunussi-Joannopoulos, K.6
  • 49
    • 33749531054 scopus 로고    scopus 로고
    • Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21
    • Good, K. L., Bryant, V. L. and Tangye, S. G., Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J. Immunol. 2006. 177: 5236-5247.
    • (2006) J. Immunol. , vol.177 , pp. 5236-5247
    • Good, K.L.1    Bryant, V.L.2    Tangye, S.G.3
  • 51
    • 68149099548 scopus 로고    scopus 로고
    • Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21
    • Hagn, M., Schwesinger, E., Ebel, V., Sontheimer, K., Maier, J., Beyer, T., Syrovets, T. et al., Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. J. Immunol. 2009. 183: 1838-1845.
    • (2009) J. Immunol. , vol.183 , pp. 1838-1845
    • Hagn, M.1    Schwesinger, E.2    Ebel, V.3    Sontheimer, K.4    Maier, J.5    Beyer, T.6    Syrovets, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.