Technologies for glycomic characterization of biopharmaceutical erythropoietins

TrAC - Trends in Analytical Chemistry

Volumn 68, Issue , 2015, Pages 18-27

  Hua, Serenus ^a,b   Oh, Myung Jin ^a,b   Ozcan, Sureyya ^a   Seo, Young Suk ^a,b   Grimm, Rudolf ^b,c   An, Hyun Joo ^a,b  

^a Asia Glycomics Reference Site   (South Korea)

^b Chungnam National University   (South Korea)

^c AGILENT TECHNOLOGIES   (United States)

Author keywords

Biopharmaceutical; Biosimilar; Darbepoetin alfa; Epoetin; Glycan; Glycomic characterization; Glycopeptide; Glycosylation; Mass spectrometry; Recombinant erythropoietin

Indexed keywords

ESTERIFICATION; MASS SPECTROMETRY;

BIOPHARMACEUTICAL; BIOSIMILAR; DARBEPOETIN ALFA; EPOETIN; ERYTHROPOIETIN (EPO); GLYCAN; GLYCOPEPTIDES;

GLYCOSYLATION;

ERYTHROPOIETIN;

ANION EXCHANGE CHROMATOGRAPHY; CAPILLARY ELECTROPHORESIS; CHROMATOGRAPHY; DERIVATIZATION; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE; FRACTIONATION; GLYCOSYLATION; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ISOELECTRIC FOCUSING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POROUS GRAPHITIZED CARBON CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 84927537064     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2015.02.004     Document Type: Review

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