Analytical platform for glycomic characterization of recombinant erythropoietin biotherapeutics and biosimilars by MS

Bioanalysis

Volumn 5, Issue 5, 2013, Pages 545-559

  Oh, Myung Jin ^a   Hua, Serenus ^a   Kim, Bum Jin ^a   Jeong, Ha Neul ^a   Jeong, Seung Hyup ^a   Grimm, Rudolf ^a,b   Yoo, Jong Shin ^a,c   An, Hyun Joo ^a  

^a Chungnam National University   (South Korea)

^b AGILENT TECHNOLOGIES   (United States)

^c Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PRODUCT; BIOSIMILAR AGENT; CARBOHYDRATE DERIVATIVE; CARBON; FUCOSE; GRAPHITE; HEXOSE; N ACETYLHEXOSAMINE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; POLYSORBATE; RECOMBINANT ERYTHROPOIETIN; SIALIC ACID; UNCLASSIFIED DRUG;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; DRUG HALF LIFE; DRUG STRUCTURE; GLYCOBIOLOGY; GLYCOSYLATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SIALYLATION; STRUCTURE ANALYSIS;

BIOSIMILAR PHARMACEUTICALS; CARBOHYDRATE CONFORMATION; ERYTHROPOIETIN; GLYCOSYLATION; HUMANS; ISOMERISM; NANOTECHNOLOGY; NEURAMINIC ACIDS; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; POLYSACCHARIDES; QUALITY CONTROL; RECOMBINANT PROTEINS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84874134892     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.327     Document Type: Article

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