Multivariate statistics for the differentiation of erythropoietin preparations based on intact glycoforms determined by CE-MS

Analytical and Bioanalytical Chemistry

Volumn 403, Issue 3, 2012, Pages 797-805

  Taichrib, Angelina ^a   Pioch, Markus ^a   Neusüß, Christian ^a  

^a AALEN UNIVERSITY   (Germany)

Author keywords

Biosimilars; Capillary electrophoresis mass spectrometry; Cluster analysis; Erythropoietin; Principal component analysis

Indexed keywords

BIOSIMILARS; CAPILLARY ELECTROPHORESIS-MASS SPECTROMETRIES; COMBINED INFORMATIONS; COMPOSITION VARIATION; ERYTHROPOIETIN (EPO); GLYCOFORMS; HIERARCHICAL AGGLOMERATIVE CLUSTERING; ISOFORMS; MULTIVARIATE STATISTICS; PEAK AREA; PRODUCTION CELLS;

ACETYLATION; CAPILLARY ELECTROPHORESIS; CELL CULTURE; CLUSTER ANALYSIS; MASS SPECTROMETRY; PRINCIPAL COMPONENT ANALYSIS;

MULTIVARIANT ANALYSIS;

ERYTHROPOIETIN; ISOPROTEIN;

CAPILLARY ELECTROPHORESIS; CARBOHYDRATE ANALYSIS; CLUSTER ANALYSIS; CONFERENCE PAPER; GLYCOSYLATION; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PRINCIPAL COMPONENT ANALYSIS;

CARBOHYDRATE SEQUENCE; CLUSTER ANALYSIS; ELECTROPHORESIS, CAPILLARY; ERYTHROPOIETIN; GLYCOSYLATION; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PRINCIPAL COMPONENT ANALYSIS; PROTEIN ISOFORMS;

EID: 84861229412     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-5924-8     Document Type: Conference Paper

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