Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin

Journal of Immunology

Volumn 168, Issue 9, 2002, Pages 4361-4371

  Ratzinger, Gudrun ^a   Stoitzner, Patrizia ^a   Ebner, Susanne ^a   Lutz, Manfred B ^a   Layton, Guy T ^a   Rainer, Christian ^a   Senior, Robert M ^a   Michael Shipley, J ^a   Fritsch, Peter ^a   Schuler, Gerold ^a   Romani, Nikolaus ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GELATINASE A; GELATINASE B; MAJOR HISTOCOMPATIBILITY ANTIGEN; MATRIX METALLOPROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; BASEMENT MEMBRANE; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; LANGERHANS CELL; LYMPHATIC DRAINAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0036568954     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.9.4361     Document Type: Article

References (55)

1. Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells
2. Dendritic cells and the control of immunity
3. New insights into the mobilization and phagocytic activity of dendritic cells
4. Human cutaneous dendritic cells migrate through dermal lymphatic vessels in a skin organ culture model
5. Entry into afferent lymphatics and maturation in situ of migrating cutaneous dendritic cells
6. Migration and maturation of Langerhans cells in skin transplants and explants
7. A close-up view of migrating Langerhans cells in the skin
8. An essential role for Langerhans cell-derived IL-1β in the initiation of primary immune responses in skin
9. Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1
10. Langerhans cells require signals from both tumour necrosis factor-α and interleukin-1β for migration
11. Migration of Langerhans cells and dermal dendritic cells in skin organ cultures: Augmentation by TNF-α and IL-1β
12. Contact allergens and epidermal proinflammatory cytokines modulate Langerhans cell E-cadherin expression in situ
13. Development of motility of Langerhans cell through extracellular matrix by in vitro hapten contact
14. The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3β are potent chemoattractants for in vitro- and in vivo-derived dendritic cells
15. Cutting edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
16. Role of specific successive contacts between extracellular matrix proteins and epidermal Langerhans cells in the control of their directed migration
17. 6 integrins are required for Langerhans cell migration from the epidermis
18. An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function
19. Matrix metalloproteinase degradation of extracellular matrix: Biological consequences
20. Focalized proteolysis: Spatial and temporal regulation of extracellular matrix degradation at the cell surface
21. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
22. Proteolysis and cell migration: Creating a path?
23. Langerhans cells express matrix metalloproteinase-9 in the human epidermis
24. Langerhans' cells produce type IV collagenase (MMP-9) following epicutaneous stimulation with haptens
25. TNF-α and IL-1β selectively induce expression of 92-kDa gelatinase by human macrophages
26. Early molecular events in the induction phase of contact sensitivity
27. Possible involvement of matrix metalloproteinase-9 in Langerhans cell migration and maturation
28. Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response
29. Dendritic cells
30. A physiologic function for p-glycoprotein (MDR-I) during the migration of dendritic cells from skin via afferent lymphatic vessels
31. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
32. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
33. Dendritic cells in the T-cell areas of lymphoid organs
34. A monoclonal Ab specifically reactive to human Langerhans cells
35. Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates
36. Human and murine dermis contain dendritic cells. Isolation by means of a novel method and phenotypical and functional characterization
37. Separation of the epidermal sheet by dispase
38. Isolation, enrichment and culture of murine epidermal Langerhans cells
39. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro
40. A small number of anti-CD3 molecules on dendritic cells stimulates DNA synthesis in mouse T lymphocytes
41. New staining techniques for the Langerhans cell
42. An improved isolation method for murine migratory cutaneous dendritic cells
43. Matrix metalloproteinase inhibitor BB-3103 unlike the serine protease inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo
44. Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-α
45. Inhibition of contact sensitizer-induced migration of human Langerhans cells by matrix metalloproteinase inhibitors
46. T cell gelatinases mediate basement membrane transmigration in vitro
47. Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B
48. Free hapten molecules are dispersed by way of the bloodstream during contact sensitization to fluorescein isothiocyanate
49. Developmental regulation of MHC class II transport in mouse dendritic cells
50. Active immunization against cancer with dendritic cells: The near future
51. Migration of human dendritic cells after injection in patients with metastatic malignancies
52. Analysis of mouse dendritic cell migration in vivo upon subcutaneous and intravenous injection
53. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration
54. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo
55. Human monocyte-derived dendritic cells produce bioactive gelatinase B: Inhibition by IFN-β