메뉴 건너뛰기




Volumn 11, Issue 1, 2013, Pages

Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients

Author keywords

Breast cancer; Clustering; Dendritic cells; Immune cells; Lymph nodes; Spatial organization

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER GRADING; CELL FUNCTION; CELL INTERACTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE FREE SURVIVAL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNE DYSREGULATION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LYMPH NODE; MAJOR CLINICAL STUDY; QUANTITATIVE ANALYSIS; T LYMPHOCYTE; TUMOR DRAINING LYMPH NODE; TUMOR IMMUNITY; TUMOR VOLUME;

EID: 84884796701     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-242     Document Type: Article
Times cited : (41)

References (35)
  • 3
    • 0037430245 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating dendritic cells expressing CD83 in human breast carcinomas
    • 10.1002/ijc.10915, 12532424
    • Iwamoto M, Shinohara H, Miyamoto A, Okuzawa M, Mabuchi H, Nohara T, Gon G, Toyoda M, Tanigawa N. Prognostic value of tumor-infiltrating dendritic cells expressing CD83 in human breast carcinomas. Int J Cancer 2003, 104(1):92-97. 10.1002/ijc.10915, 12532424.
    • (2003) Int J Cancer , vol.104 , Issue.1 , pp. 92-97
    • Iwamoto, M.1    Shinohara, H.2    Miyamoto, A.3    Okuzawa, M.4    Mabuchi, H.5    Nohara, T.6    Gon, G.7    Toyoda, M.8    Tanigawa, N.9
  • 4
    • 0036278521 scopus 로고    scopus 로고
    • Alterations in the frequency of dendritic cell subsets in the peripheral circulation of patients with squamous cell carcinomas of the head and neck
    • Hoffmann TK, Muller-Berghaus J, Ferris RL, Johnson JT, Storkus WJ, Whiteside TL. Alterations in the frequency of dendritic cell subsets in the peripheral circulation of patients with squamous cell carcinomas of the head and neck. Clin Cancer Res 2002, 8(6):1787-1793.
    • (2002) Clin Cancer Res , vol.8 , Issue.6 , pp. 1787-1793
    • Hoffmann, T.K.1    Muller-Berghaus, J.2    Ferris, R.L.3    Johnson, J.T.4    Storkus, W.J.5    Whiteside, T.L.6
  • 5
    • 0034883882 scopus 로고    scopus 로고
    • Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1
    • Lissoni P, Malugani F, Bonfanti A, Bucovec R, Secondino S, Brivio F, Ferrari-Bravo A, Ferrante R, Vigore L, Rovelli F, et al. Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1. J Biol Regul Homeost Agents 2001, 15(2):140-144.
    • (2001) J Biol Regul Homeost Agents , vol.15 , Issue.2 , pp. 140-144
    • Lissoni, P.1    Malugani, F.2    Bonfanti, A.3    Bucovec, R.4    Secondino, S.5    Brivio, F.6    Ferrari-Bravo, A.7    Ferrante, R.8    Vigore, L.9    Rovelli, F.10
  • 8
    • 0033060409 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells in adenocarcinomas of the breast: a study of 143 neoplasms with a correlation to usual prognostic factors and to clinical outcome
    • 10.1002/(SICI)1097-0215(19990621)84:3<309::AID-IJC19>3.0.CO;2-3, 10371352
    • Lespagnard L, Gancberg D, Rouas G, Leclercq G, de Saint-Aubain SN, Di Leo A, Piccart M, Verhest A, Larsimont D. Tumor-infiltrating dendritic cells in adenocarcinomas of the breast: a study of 143 neoplasms with a correlation to usual prognostic factors and to clinical outcome. Int J Cancer 1999, 84(3):309-314. 10.1002/(SICI)1097-0215(19990621)84:3<309::AID-IJC19>3.0.CO;2-3, 10371352.
    • (1999) Int J Cancer , vol.84 , Issue.3 , pp. 309-314
    • Lespagnard, L.1    Gancberg, D.2    Rouas, G.3    Leclercq, G.4    de Saint-Aubain, S.N.5    Di Leo, A.6    Piccart, M.7    Verhest, A.8    Larsimont, D.9
  • 9
    • 0024548430 scopus 로고
    • S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis
    • 10.1002/1097-0142(19890201)63:3<496::AID-CNCR2820630318>3.0.CO;2-K, 2912528
    • Ambe K, Mori M, Enjoji M. S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis. Cancer 1989, 63(3):496-503. 10.1002/1097-0142(19890201)63:3<496::AID-CNCR2820630318>3.0.CO;2-K, 2912528.
    • (1989) Cancer , vol.63 , Issue.3 , pp. 496-503
    • Ambe, K.1    Mori, M.2    Enjoji, M.3
  • 10
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • 10.1038/nri1498, 15573129
    • Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 2004, 4(12):941-952. 10.1038/nri1498, 15573129.
    • (2004) Nat Rev Immunol , vol.4 , Issue.12 , pp. 941-952
    • Gabrilovich, D.1
  • 11
    • 0033571785 scopus 로고    scopus 로고
    • In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
    • 10.1084/jem.190.10.1417, 2195690, 10562317
    • Bell D, Chomarat P, Broyles D, Netto G, Harb GM, Lebecque S, Valladeau J, Davoust J, Palucka KA, Banchereau J. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 1999, 190(10):1417-1426. 10.1084/jem.190.10.1417, 2195690, 10562317.
    • (1999) J Exp Med , vol.190 , Issue.10 , pp. 1417-1426
    • Bell, D.1    Chomarat, P.2    Broyles, D.3    Netto, G.4    Harb, G.M.5    Lebecque, S.6    Valladeau, J.7    Davoust, J.8    Palucka, K.A.9    Banchereau, J.10
  • 12
    • 0034049287 scopus 로고    scopus 로고
    • Infiltrating dendritic/Langerhans cells in primary breast cancer
    • 10.1023/A:1006396216933, 10817349
    • Tsuge T, Yamakawa M, Tsukamoto M. Infiltrating dendritic/Langerhans cells in primary breast cancer. Breast Cancer Res Treat 2000, 59(2):141-152. 10.1023/A:1006396216933, 10817349.
    • (2000) Breast Cancer Res Treat , vol.59 , Issue.2 , pp. 141-152
    • Tsuge, T.1    Yamakawa, M.2    Tsukamoto, M.3
  • 14
    • 0242407162 scopus 로고    scopus 로고
    • Altered maturation of peripheral blood dendritic cells in patients with breast cancer
    • 10.1038/sj.bjc.6601243, 2394334, 14562018
    • Della Bella S, Gennaro M, Vaccari M, Ferraris C, Nicola S, Riva A, Clerici M, Greco M, Villa ML. Altered maturation of peripheral blood dendritic cells in patients with breast cancer. Br J Cancer 2003, 89(8):1463-1472. 10.1038/sj.bjc.6601243, 2394334, 14562018.
    • (2003) Br J Cancer , vol.89 , Issue.8 , pp. 1463-1472
    • Della Bella, S.1    Gennaro, M.2    Vaccari, M.3    Ferraris, C.4    Nicola, S.5    Riva, A.6    Clerici, M.7    Greco, M.8    Villa, M.L.9
  • 15
    • 25644432763 scopus 로고    scopus 로고
    • Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer
    • 10.1371/journal.pmed.0020284, 1198041, 16124834
    • Kohrt HE, Nouri N, Nowels K, Johnson D, Holmes S, Lee PP. Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer. PLoS Med 2005, 2(9):e284. 10.1371/journal.pmed.0020284, 1198041, 16124834.
    • (2005) PLoS Med , vol.2 , Issue.9
    • Kohrt, H.E.1    Nouri, N.2    Nowels, K.3    Johnson, D.4    Holmes, S.5    Lee, P.P.6
  • 16
    • 0035107187 scopus 로고    scopus 로고
    • Homotypic cluster formation of dendritic cells, a close correlate of their state of maturation. Defects in the biobreeding diabetes-prone rat
    • Delemarre FG, Hoogeveen PG, De Haan-Meulman M, Simons PJ, Drexhage HA. Homotypic cluster formation of dendritic cells, a close correlate of their state of maturation. Defects in the biobreeding diabetes-prone rat. J Leukoc Biol 2001, 69(3):373-380.
    • (2001) J Leukoc Biol , vol.69 , Issue.3 , pp. 373-380
    • Delemarre, F.G.1    Hoogeveen, P.G.2    De Haan-Meulman, M.3    Simons, P.J.4    Drexhage, H.A.5
  • 17
    • 83655201412 scopus 로고    scopus 로고
    • Increased influx of myeloid dendritic cells during acute rejection is associated with interstitial fibrosis and tubular atrophy and predicts poor outcome
    • Zuidwijk K, de Fijter JW, Mallat MJ, Eikmans M, van Groningen MC, Goemaere NN, Bajema IM, van Kooten C. Increased influx of myeloid dendritic cells during acute rejection is associated with interstitial fibrosis and tubular atrophy and predicts poor outcome. Kidney Int 2011, 81(1):64-75.
    • (2011) Kidney Int , vol.81 , Issue.1 , pp. 64-75
    • Zuidwijk, K.1    de Fijter, J.W.2    Mallat, M.J.3    Eikmans, M.4    van Groningen, M.C.5    Goemaere, N.N.6    Bajema, I.M.7    van Kooten, C.8
  • 18
    • 33744752786 scopus 로고    scopus 로고
    • Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis
    • 10.2353/ajpath.2006.050228, 1606612, 16723705
    • Leithauser F, Meinhardt-Krajina T, Fink K, Wotschke B, Moller P, Reimann J. Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am J Pathol 2006, 168(6):1898-1909. 10.2353/ajpath.2006.050228, 1606612, 16723705.
    • (2006) Am J Pathol , vol.168 , Issue.6 , pp. 1898-1909
    • Leithauser, F.1    Meinhardt-Krajina, T.2    Fink, K.3    Wotschke, B.4    Moller, P.5    Reimann, J.6
  • 19
    • 79957994115 scopus 로고    scopus 로고
    • An interactive java statistical image segmentation system: GemIdent
    • pii: i10
    • Holmes S, Kapelner A, Lee PP. An interactive java statistical image segmentation system: GemIdent. J Stat Softw 2009, 30(10):pii: i10.
    • (2009) J Stat Softw , vol.30 , Issue.10
    • Holmes, S.1    Kapelner, A.2    Lee, P.P.3
  • 20
    • 78049493470 scopus 로고    scopus 로고
    • Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes
    • 10.1371/journal.pone.0012420, 2928294, 20811638
    • Setiadi AF, Ray NC, Kohrt HE, Kapelner A, Carcamo-Cavazos V, Levic EB, Yadegarynia S, van der Loos CM, Schwartz EJ, Holmes S, et al. Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes. PLoS One 2010, 5(8):e12420. 10.1371/journal.pone.0012420, 2928294, 20811638.
    • (2010) PLoS One , vol.5 , Issue.8
    • Setiadi, A.F.1    Ray, N.C.2    Kohrt, H.E.3    Kapelner, A.4    Carcamo-Cavazos, V.5    Levic, E.B.6    Yadegarynia, S.7    van der Loos, C.M.8    Schwartz, E.J.9    Holmes, S.10
  • 21
    • 22144439431 scopus 로고    scopus 로고
    • Geometric algorithms for density-based data clustering
    • Chen DZ, Smid M, Xu B. Geometric algorithms for density-based data clustering. Int J Comput Geometry Appl 2005, 15(3):239-260.
    • (2005) Int J Comput Geometry Appl , vol.15 , Issue.3 , pp. 239-260
    • Chen, D.Z.1    Smid, M.2    Xu, B.3
  • 22
    • 5444229324 scopus 로고    scopus 로고
    • Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes
    • 10.1084/jem.20041236, 2213293, 15466619
    • Miller MJ, Safrina O, Parker I, Cahalan MD. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med 2004, 200(7):847-856. 10.1084/jem.20041236, 2213293, 15466619.
    • (2004) J Exp Med , vol.200 , Issue.7 , pp. 847-856
    • Miller, M.J.1    Safrina, O.2    Parker, I.3    Cahalan, M.D.4
  • 23
    • 29144508613 scopus 로고    scopus 로고
    • Dendritic cell dysfunction in cancer: a mechanism for immunosuppression
    • 10.1111/j.1440-1711.2005.01371.x, 16174093
    • Pinzon-Charry A, Maxwell T, Lopez JA. Dendritic cell dysfunction in cancer: a mechanism for immunosuppression. Immunol Cell Biol 2005, 83(5):451-461. 10.1111/j.1440-1711.2005.01371.x, 16174093.
    • (2005) Immunol Cell Biol , vol.83 , Issue.5 , pp. 451-461
    • Pinzon-Charry, A.1    Maxwell, T.2    Lopez, J.A.3
  • 24
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • 10.1038/nri1592, 15803149
    • Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005, 5(4):296-306. 10.1038/nri1592, 15803149.
    • (2005) Nat Rev Immunol , vol.5 , Issue.4 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 26
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • 10.1126/science.1129139, 17008531
    • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C, Tosolini M, Camus M, Berger A, Wind P, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006, 313(5795):1960-1964. 10.1126/science.1129139, 17008531.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6    Tosolini, M.7    Camus, M.8    Berger, A.9    Wind, P.10
  • 27
    • 84855980204 scopus 로고    scopus 로고
    • Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis
    • 10.1111/j.1600-6143.2011.03797.x, 22553852
    • Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ. Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis. Am J Transplant 2012, 12(1):27-37. 10.1111/j.1600-6143.2011.03797.x, 22553852.
    • (2012) Am J Transplant , vol.12 , Issue.1 , pp. 27-37
    • Isse, K.1    Lesniak, A.2    Grama, K.3    Roysam, B.4    Minervini, M.I.5    Demetris, A.J.6
  • 28
    • 84862827080 scopus 로고    scopus 로고
    • Utility of multispectral imaging in automated quantitative scoring of immunohistochemistry
    • 10.1136/jclinpath-2012-200734, 3437674, 22447914
    • Fiore C, Bailey D, Conlon N, Wu X, Martin N, Fiorentino M, Finn S, Fall K, Andersson SO, Andren O, et al. Utility of multispectral imaging in automated quantitative scoring of immunohistochemistry. J Clin Pathol 2012, 65(6):496-502. 10.1136/jclinpath-2012-200734, 3437674, 22447914.
    • (2012) J Clin Pathol , vol.65 , Issue.6 , pp. 496-502
    • Fiore, C.1    Bailey, D.2    Conlon, N.3    Wu, X.4    Martin, N.5    Fiorentino, M.6    Finn, S.7    Fall, K.8    Andersson, S.O.9    Andren, O.10
  • 29
    • 33746917576 scopus 로고    scopus 로고
    • CD83: a regulatory molecule of the immune system with great potential for therapeutic application
    • Fujimoto Y, Tedder TF. CD83: a regulatory molecule of the immune system with great potential for therapeutic application. J Med Dent Sci 2006, 53(2):85-91.
    • (2006) J Med Dent Sci , vol.53 , Issue.2 , pp. 85-91
    • Fujimoto, Y.1    Tedder, T.F.2
  • 30
    • 0033026753 scopus 로고    scopus 로고
    • Immunohistochemical localization of CD1a-positive putative dendritic cells in human breast tumours
    • 2362664, 10070894
    • Hillenbrand EE, Neville AM, Coventry BJ. Immunohistochemical localization of CD1a-positive putative dendritic cells in human breast tumours. Br J Cancer 1999, 79(5-6):940-944. 2362664, 10070894.
    • (1999) Br J Cancer , vol.79 , Issue.5-6 , pp. 940-944
    • Hillenbrand, E.E.1    Neville, A.M.2    Coventry, B.J.3
  • 31
    • 0037065962 scopus 로고    scopus 로고
    • Dendritic cell density and activation status in human breast cancer - CD1a, CMRF-44, CMRF-56 and CD-83 expression
    • 10.1038/sj.bjc.6600132, 2375292, 11870535
    • Coventry BJ, Lee PL, Gibbs D, Hart DN. Dendritic cell density and activation status in human breast cancer - CD1a, CMRF-44, CMRF-56 and CD-83 expression. Br J Cancer 2002, 86(4):546-551. 10.1038/sj.bjc.6600132, 2375292, 11870535.
    • (2002) Br J Cancer , vol.86 , Issue.4 , pp. 546-551
    • Coventry, B.J.1    Lee, P.L.2    Gibbs, D.3    Hart, D.N.4
  • 32
    • 80855139770 scopus 로고    scopus 로고
    • Metastasis to sentinel lymph nodes in breast cancer is associated with maturation arrest of dendritic cells and poor co-localization of dendritic cells and CD8+ T cells
    • 10.1007/s00428-011-1145-3, 21894561
    • Mansfield AS, Heikkila P, von Smitten K, Vakkila J, Leidenius M. Metastasis to sentinel lymph nodes in breast cancer is associated with maturation arrest of dendritic cells and poor co-localization of dendritic cells and CD8+ T cells. Virchows Arch 2011, 459(4):391-398. 10.1007/s00428-011-1145-3, 21894561.
    • (2011) Virchows Arch , vol.459 , Issue.4 , pp. 391-398
    • Mansfield, A.S.1    Heikkila, P.2    von Smitten, K.3    Vakkila, J.4    Leidenius, M.5
  • 33
    • 3242679690 scopus 로고    scopus 로고
    • CD1a in human cancers: a new role for an old molecule
    • 10.1016/j.it.2004.03.002, 15099564
    • Coventry B, Heinzel S. CD1a in human cancers: a new role for an old molecule. Trends Immunol 2004, 25(5):242-248. 10.1016/j.it.2004.03.002, 15099564.
    • (2004) Trends Immunol , vol.25 , Issue.5 , pp. 242-248
    • Coventry, B.1    Heinzel, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.