CMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions

Cell Research

Volumn 25, Issue 4, 2015, Pages 429-444

  Sun, Linchong ^a   Song, Libing ^b   Wan, Qianfen ^c   Wu, Gongwei ^a   Li, Xinghua ^b   Wang, Yinghui ^a   Wang, Jin ^c   Liu, Zhaoji ^a   Zhong, Xiuying ^a   He, Xiaoping ^a   Shen, Shengqi ^a   Pan, Xin ^d   Li, Ailing ^d   Wang, Yulan ^c,e   Gao, Ping ^a   Tang, Huiru ^c,f   Zhang, Huafeng ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d NATIONAL CENTER OF BIOMEDICAL ANALYSIS   (China)

^e ZHEJIANG UNIVERSITY   (China)

^f FUDAN UNIVERSITY   (China)

Author keywords

Cancer; CMyc; Metabolism; PSPH; SSP

Indexed keywords

AMINOTRANSFERASE; GLUTATHIONE; MYC PROTEIN; PHOSPHATASE; PHOSPHOSERINE AMINOTRANSFERASE; PHOSPHOSERINE PHOSPHATASE; SERINE;

ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL PROLIFERATION; ENZYMOLOGY; FOOD DEPRIVATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MOUSE; PATHOLOGY;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; FOOD DEPRIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HUMANS; LIVER NEOPLASMS; METABOLIC NETWORKS AND PATHWAYS; MICE; PHOSPHORIC MONOESTER HYDROLASES; PROTO-ONCOGENE PROTEINS C-MYC; SERINE; TRANSAMINASES;

EID: 84926520380     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2015.33     Document Type: Article

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