MDA5 plays a critical role in interferon response during hepatitis C virus infection

Journal of Hepatology

Volumn 62, Issue 4, 2015, Pages 771-778

  Cao, Xuezhi ^a   Ding, Qiang ^a   Lu, Jie ^a   Tao, Wanyin ^a   Huang, Bing ^a   Zhao, Yanan ^a   Niu, Junqi ^a,b   Liu, Yong Jun ^a,c   Zhong, Jin ^a  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^c BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

Author keywords

HCV; Innate immunity; Interferon; MDA5

Indexed keywords

BETA INTERFERON; HELICASE; MDA5 PROTEIN; MESSENGER RNA; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; CELL RECEPTOR; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; INTERFERON; INTERFERON REGULATORY FACTOR; NS3 PROTEIN, HEPATITIS C VIRUS; SERINE PROTEINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VIRUS PROTEIN; VISA PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CRISPR CAS SYSTEM; HEPATITIS C; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; INNATE IMMUNITY; INTERFERON INDUCTION; INTERFERON PRODUCTION; LIVER CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; VIRUS REPLICATION; CELL LINE; CHRONIC HEPATITIS C; GENETICS; HEPACIVIRUS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

3' UNTRANSLATED REGIONS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; DEAD-BOX RNA HELICASES; HEPACIVIRUS; HEPATITIS C, CHRONIC; HEPATOCYTES; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTORS; INTERFERONS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84926421887     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.11.007     Document Type: Article

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