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Volumn , Issue , 2014, Pages 117-144

The Aryl Hydrocarbon Receptor (AhR) as a Mediator of Adverse Immune Reactions

Author keywords

Aryl hydrocarbon receptor in gut immunity; Chemical induced immunosuppression; Dendritic cells; Dioxin; Immunotoxicity of dioxins; TCDD; Th17; Vietnam Veterans

Indexed keywords


EID: 84926249793     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527676965.ch6     Document Type: Chapter
Times cited : (1)

References (128)
  • 1
    • 84858785444 scopus 로고    scopus 로고
    • TCDD: an environmental immunotoxicant reveals a novel pathway of immunoregulation-a 30-year odyssey
    • Kerkvliet, N.I. (2012) TCDD: an environmental immunotoxicant reveals a novel pathway of immunoregulation-a 30-year odyssey. Toxicol. Pathol., 40, 138-142.
    • (2012) Toxicol. Pathol. , vol.40 , pp. 138-142
    • Kerkvliet, N.I.1
  • 2
    • 67449119139 scopus 로고    scopus 로고
    • Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice
    • Jux, B., Kadow, S., and Esser, C. (2009) Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice. J. Immunol., 182, 6709-6717.
    • (2009) J. Immunol. , vol.182 , pp. 6709-6717
    • Jux, B.1    Kadow, S.2    Esser, C.3
  • 3
    • 77953460148 scopus 로고    scopus 로고
    • Esser C small molecules as friends and foes of the immune system
    • Kadow, S., Jux, B., and Chmill, S. (2009) Esser C small molecules as friends and foes of the immune system. Future Med. Chem., 1 (9), 1583-1591.
    • (2009) Future Med. Chem. , vol.1 , Issue.9 , pp. 1583-1591
    • Kadow, S.1    Jux, B.2    Chmill, S.3
  • 9
    • 83855160821 scopus 로고    scopus 로고
    • Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles
    • Kiss, E.A., Vonarbourg, C., Kopfmann, S., Hobeika, E., Finke, D., Esser, C., and Diefenbach, A. (2011) Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science. doi: 10.1126/science.1214914
    • (2011) Science
    • Kiss, E.A.1    Vonarbourg, C.2    Kopfmann, S.3    Hobeika, E.4    Finke, D.5    Esser, C.6    Diefenbach, A.7
  • 10
    • 0036147662 scopus 로고    scopus 로고
    • Recent advances in understanding the mechanisms of TCDD immunotoxicity
    • Kerkvliet, N.I. (2002) Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int. Immunopharmacol., 2, 277-291.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 277-291
    • Kerkvliet, N.I.1
  • 11
  • 13
    • 49449095646 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound
    • Lawrence, B.P., Denison, M.S., Novak, H., Vorderstrasse, B.A., Harrer, N., Neruda, W., Reichel, C., and Woisetschlager, M. (2008) Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood, 112, 1158-1165.
    • (2008) Blood , vol.112 , pp. 1158-1165
    • Lawrence, B.P.1    Denison, M.S.2    Novak, H.3    Vorderstrasse, B.A.4    Harrer, N.5    Neruda, W.6    Reichel, C.7    Woisetschlager, M.8
  • 15
    • 39549103852 scopus 로고    scopus 로고
    • Hormonal influences in multiple sclerosis
    • Shuster, E.A. (2008) Hormonal influences in multiple sclerosis. Curr. Top. Microbiol. Immunol., 318, 267-311.
    • (2008) Curr. Top. Microbiol. Immunol. , vol.318 , pp. 267-311
    • Shuster, E.A.1
  • 16
    • 0037148507 scopus 로고    scopus 로고
    • Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression
    • Walterscheid, J.P., Ullrich, S.E., and Nghiem, D.X. (2002) Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression. J. Exp. Med., 195, 171-179.
    • (2002) J. Exp. Med. , vol.195 , pp. 171-179
    • Walterscheid, J.P.1    Ullrich, S.E.2    Nghiem, D.X.3
  • 17
    • 67349127266 scopus 로고    scopus 로고
    • Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
    • Yao, C., Sakata, D., Esaki, Y., Li, Y., Matsuoka, T., Kuroiwa, K., Sugimoto, Y., and Narumiya, S. (2009) Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. Nat. Med., 15, 633-640.
    • (2009) Nat. Med. , vol.15 , pp. 633-640
    • Yao, C.1    Sakata, D.2    Esaki, Y.3    Li, Y.4    Matsuoka, T.5    Kuroiwa, K.6    Sugimoto, Y.7    Narumiya, S.8
  • 18
    • 27144476792 scopus 로고    scopus 로고
    • A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation
    • Braun, D., Longman, R.S., and Albert, M.L. (2005) A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood, 106, 2375-2381.
    • (2005) Blood , vol.106 , pp. 2375-2381
    • Braun, D.1    Longman, R.S.2    Albert, M.L.3
  • 19
    • 60549107576 scopus 로고    scopus 로고
    • Induction of tolerogenic dendritic cells by vitamin D receptor agonists
    • Adorini, L. and Penna, G. (2009) Induction of tolerogenic dendritic cells by vitamin D receptor agonists. Handb. Exp. Pharmacol., 188, 251-273.
    • (2009) Handb. Exp. Pharmacol. , vol.188 , pp. 251-273
    • Adorini, L.1    Penna, G.2
  • 21
    • 34547751351 scopus 로고    scopus 로고
    • Oral tolerance:is it all retinoic acid?
    • von Boehmer, H. (2007) Oral tolerance:is it all retinoic acid? J. Exp. Med., 204, 1737-1739.
    • (2007) J. Exp. Med. , vol.204 , pp. 1737-1739
    • von Boehmer, H.1
  • 23
    • 0031789983 scopus 로고    scopus 로고
    • Signaltransduction cascades as targets for therapeutic intervention by natural products
    • Cardenas, M.E., Sanfridson, A., Cutler, N.S., and Heitman, J. (1998) Signaltransduction cascades as targets for therapeutic intervention by natural products. Trends Biotechnol., 16, 427-433.
    • (1998) Trends Biotechnol. , vol.16 , pp. 427-433
    • Cardenas, M.E.1    Sanfridson, A.2    Cutler, N.S.3    Heitman, J.4
  • 25
    • 0032726481 scopus 로고    scopus 로고
    • Immunomodulation by thalidomide and thalidomide analogues
    • Corral, L.G. and Kaplan, G. (1999) Immunomodulation by thalidomide and thalidomide analogues. Ann. Rheum. Dis., 58 (Suppl. 1), I107-I113.
    • (1999) Ann. Rheum. Dis. , vol.58 , pp. I107-I113
    • Corral, L.G.1    Kaplan, G.2
  • 27
    • 0023600014 scopus 로고
    • Biological activity of organotin compounds-an overview
    • Snoeij, N.J., Penninks, A.H., and Seinen, W. (1987) Biological activity of organotin compounds-an overview. Environ. Res., 44, 335-353.
    • (1987) Environ. Res. , vol.44 , pp. 335-353
    • Snoeij, N.J.1    Penninks, A.H.2    Seinen, W.3
  • 29
    • 49649088935 scopus 로고    scopus 로고
    • Integrated approach to immunotoxicity:electron transfer, reactive oxygen species, antioxidants, cell signaling, and receptors
    • Kovacic, P. and Somanathan, R. (2008) Integrated approach to immunotoxicity:electron transfer, reactive oxygen species, antioxidants, cell signaling, and receptors. J. Recept. Signal Transduct. Res., 28, 323-346.
    • (2008) J. Recept. Signal Transduct. Res. , vol.28 , pp. 323-346
    • Kovacic, P.1    Somanathan, R.2
  • 30
    • 0036803050 scopus 로고    scopus 로고
    • A role for associated transition metals in the immunotoxicity of inhaled ambient particulate matter
    • Zelikoff, J.T., Schermerhorn, K.R., Fang, K., Cohen, M.D., and Schlesinger, R.B. (2002) A role for associated transition metals in the immunotoxicity of inhaled ambient particulate matter. Environ. Health Perspect., 110 (Suppl. 5), 871-875.
    • (2002) Environ. Health Perspect. , vol.110 , pp. 871-875
    • Zelikoff, J.T.1    Schermerhorn, K.R.2    Fang, K.3    Cohen, M.D.4    Schlesinger, R.B.5
  • 31
    • 0021157252 scopus 로고
    • The immunotoxicity of selected environmental chemicals, pesticides and heavy metals
    • Exon, J.H. (1984) The immunotoxicity of selected environmental chemicals, pesticides and heavy metals. Prog. Clin. Biol. Res., 161, 355-368.
    • (1984) Prog. Clin. Biol. Res. , vol.161 , pp. 355-368
    • Exon, J.H.1
  • 32
    • 0025951523 scopus 로고
    • A review of 2,3,7,8-tetrachlorodibenzo-p-dioxininduced changes in immunocompetence:1991 update
    • Holsapple, M.P., Snyder, N.K., Wood, S.C., and Morris, D.L. (1991) A review of 2,3,7,8-tetrachlorodibenzo-p-dioxininduced changes in immunocompetence:1991 update. Toxicology, 69, 219-255.
    • (1991) Toxicology , vol.69 , pp. 219-255
    • Holsapple, M.P.1    Snyder, N.K.2    Wood, S.C.3    Morris, D.L.4
  • 35
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison, M.S. and Nagy, S.R. (2003) Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol., 43, 309-334.
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 36
    • 1642535318 scopus 로고    scopus 로고
    • Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-pdioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction
    • Ma, Q., Kinneer, K., Bi, Y., Chan, J.Y., and Kan, Y.W. (2004) Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-pdioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction. Biochem. J., 377, 205-213.
    • (2004) Biochem. J. , vol.377 , pp. 205-213
    • Ma, Q.1    Kinneer, K.2    Bi, Y.3    Chan, J.Y.4    Kan, Y.W.5
  • 37
    • 0031459411 scopus 로고    scopus 로고
    • Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family
    • Hahn, M.E., Karchner, S.I., Shapiro, M.A., and Perera, S.A. (1997) Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family. Proc. Natl. Acad. Sci. U.S.A., 94, 13743-13748.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 13743-13748
    • Hahn, M.E.1    Karchner, S.I.2    Shapiro, M.A.3    Perera, S.A.4
  • 38
    • 0030598390 scopus 로고    scopus 로고
    • Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway
    • Enan, E. and Matsumura, F. (1996) Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway. Biochem. Pharmacol., 52, 1599-1612.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1599-1612
    • Enan, E.1    Matsumura, F.2
  • 39
    • 34447511096 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
    • Barouki, R., Coumoul, X., and Fernandez-Salguero, P.M. (2007) The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett., 581, 3608-3615.
    • (2007) FEBS Lett. , vol.581 , pp. 3608-3615
    • Barouki, R.1    Coumoul, X.2    Fernandez-Salguero, P.M.3
  • 40
    • 0029059548 scopus 로고
    • Distinct functions for the two importin subunits in nuclear protein import
    • Gorlich, D., Vogel, F., Mills, A.D., Hartmann, E., and Laskey, R.A. (1995) Distinct functions for the two importin subunits in nuclear protein import. Nature, 377, 246-248.
    • (1995) Nature , vol.377 , pp. 246-248
    • Gorlich, D.1    Vogel, F.2    Mills, A.D.3    Hartmann, E.4    Laskey, R.A.5
  • 41
    • 4344590127 scopus 로고    scopus 로고
    • Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences
    • Sun, Y.V., Boverhof, D.R., Burgoon, L.D., Fielden, M.R., and Zacharewski, T.R. (2004) Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences. Nucleic Acids Res., 32, 4512-4523.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 4512-4523
    • Sun, Y.V.1    Boverhof, D.R.2    Burgoon, L.D.3    Fielden, M.R.4    Zacharewski, T.R.5
  • 42
    • 34247240980 scopus 로고    scopus 로고
    • Microarray analysis of the AHR system: tissue-specific flexibility in signal and target genes
    • Frericks, M., Meissner, M., and Esser, C. (2007) Microarray analysis of the AHR system: tissue-specific flexibility in signal and target genes. Toxicol. Appl. Pharmacol., 220, 320-332.
    • (2007) Toxicol. Appl. Pharmacol. , vol.220 , pp. 320-332
    • Frericks, M.1    Meissner, M.2    Esser, C.3
  • 43
    • 0037119867 scopus 로고    scopus 로고
    • Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxininduced gene expression profile in vivo using pathway-specific cDNA arrays
    • Zeytun, A., McKallip, R.J., Fisher, M., Camacho, I., Nagarkatti, M., and Nagarkatti, P.S. (2002) Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxininduced gene expression profile in vivo using pathway-specific cDNA arrays. Toxicology, 178, 241-260.
    • (2002) Toxicology , vol.178 , pp. 241-260
    • Zeytun, A.1    McKallip, R.J.2    Fisher, M.3    Camacho, I.4    Nagarkatti, M.5    Nagarkatti, P.S.6
  • 44
    • 79954496051 scopus 로고    scopus 로고
    • Genome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes
    • Dere, E., Forgacs, A.L., Zacharewski, T.R., and Burgoon, L.D. (2011) Genome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes. Chem. Res. Toxicol., 24, 494-504.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 494-504
    • Dere, E.1    Forgacs, A.L.2    Zacharewski, T.R.3    Burgoon, L.D.4
  • 45
    • 0018191622 scopus 로고
    • Medical problems raised by the TCDD contamination in Seveso
    • Reggiani, G. (1978) Medical problems raised by the TCDD contamination in Seveso. Italy. Arch. Toxicol., 40, 161-188.
    • (1978) Italy. Arch. Toxicol. , vol.40 , pp. 161-188
    • Reggiani, G.1
  • 46
    • 84155196846 scopus 로고    scopus 로고
    • Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
    • Denison, M.S., Soshilov, A.A., He, G., DeGroot, D.E., and Zhao, B. (2011) Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol. Sci., 124, 1-22.
    • (2011) Toxicol. Sci. , vol.124 , pp. 1-22
    • Denison, M.S.1    Soshilov, A.A.2    He, G.3    DeGroot, D.E.4    Zhao, B.5
  • 47
    • 59149086780 scopus 로고    scopus 로고
    • The immune system of Ahr null mutant mouse strains - not a simple mirror of xenobiotic receptor over-activation
    • Esser, C. (2009) The immune system of Ahr null mutant mouse strains - not a simple mirror of xenobiotic receptor over-activation. Biochem. Pharmacol., 77, 597-607.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 597-607
    • Esser, C.1
  • 48
    • 40949107666 scopus 로고    scopus 로고
    • Molecular determinants of speciesspecific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor
    • Henry, E.C. and Gasiewicz, T.A. (2008) Molecular determinants of speciesspecific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor. Arch. Biochem. Biophys., 472, 77-88.
    • (2008) Arch. Biochem. Biophys. , vol.472 , pp. 77-88
    • Henry, E.C.1    Gasiewicz, T.A.2
  • 49
    • 0036615860 scopus 로고    scopus 로고
    • Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormonedependent cancers (Review)
    • Safe, S. and McDougal, A. (2002) Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormonedependent cancers (Review). Int. J. Oncol., 20, 1123-1128.
    • (2002) Int. J. Oncol. , vol.20 , pp. 1123-1128
    • Safe, S.1    McDougal, A.2
  • 50
    • 0015528243 scopus 로고
    • Aryl hydrocarbon hydroxylase induction by polycyclic hydrocarbons: simple autosomal dominant trait in the mouse
    • Nebert, D.W., Goujon, F.M., and Gielen, J.E. (1972) Aryl hydrocarbon hydroxylase induction by polycyclic hydrocarbons: simple autosomal dominant trait in the mouse. Nat. New Biol., 236, 107-110.
    • (1972) Nat. New Biol. , vol.236 , pp. 107-110
    • Nebert, D.W.1    Goujon, F.M.2    Gielen, J.E.3
  • 51
    • 30044452058 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates distinct dioxindependent and dioxin-independent gene batteries
    • Tijet, N., Boutros, P.C., Moffat, I.D., Okey, A.B., Tuomisto, J., and Pohjanvirta, R. (2006) Aryl hydrocarbon receptor regulates distinct dioxindependent and dioxin-independent gene batteries. Mol. Pharmacol., 69, 140-153.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 52
    • 33748747782 scopus 로고    scopus 로고
    • Transcriptional signatures of immune cells in aryl hydrocarbon receptor (AHR)-proficient and AHR-deficient mice
    • Frericks, M., Temchura, V.V., Majora, M., Stutte, S., and Esser, C. (2006) Transcriptional signatures of immune cells in aryl hydrocarbon receptor (AHR)-proficient and AHR-deficient mice. Biol. Chem., 387, 1219-1226.
    • (2006) Biol. Chem. , vol.387 , pp. 1219-1226
    • Frericks, M.1    Temchura, V.V.2    Majora, M.3    Stutte, S.4    Esser, C.5
  • 53
    • 59149104324 scopus 로고    scopus 로고
    • A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family
    • Vogel, C.F. and Matsumura, F. (2009) A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem. Pharmacol., 77, 734-745.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 734-745
    • Vogel, C.F.1    Matsumura, F.2
  • 55
    • 20444381667 scopus 로고    scopus 로고
    • ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription
    • Beischlag, T.V. and Perdew, G.H. (2005) ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. J. Biol. Chem., 280, 21607-21611.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21607-21611
    • Beischlag, T.V.1    Perdew, G.H.2
  • 56
    • 84876803753 scopus 로고    scopus 로고
    • Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes
    • Forgacs, A.L., Dere, E., Angrish, M.M., and Zacharewski, T.R. (2013) Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes. Toxicol. Sci., 133, 54-66.
    • (2013) Toxicol. Sci. , vol.133 , pp. 54-66
    • Forgacs, A.L.1    Dere, E.2    Angrish, M.M.3    Zacharewski, T.R.4
  • 57
    • 9944255780 scopus 로고    scopus 로고
    • Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor
    • Hankinson, O. (2005) Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor. Arch. Biochem. Biophys., 433, 379-386.
    • (2005) Arch. Biochem. Biophys. , vol.433 , pp. 379-386
    • Hankinson, O.1
  • 58
    • 0041631065 scopus 로고    scopus 로고
    • Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells
    • Nakajima, M., Iwanari, M., and Yokoi, T. (2003) Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells. Toxicol. Lett., 144, 247-256.
    • (2003) Toxicol. Lett. , vol.144 , pp. 247-256
    • Nakajima, M.1    Iwanari, M.2    Yokoi, T.3
  • 59
    • 59149097949 scopus 로고    scopus 로고
    • Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor
    • Hahn, M.E., Allan, L.L., and Sherr, D.H. (2009) Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor. Biochem. Pharmacol., 77, 485-497.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 485-497
    • Hahn, M.E.1    Allan, L.L.2    Sherr, D.H.3
  • 60
    • 84858626055 scopus 로고    scopus 로고
    • Inhibition of cytochrome P4501- dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor
    • Wincent, E., Bengtsson, J., Mohammadi, B.A., Alsberg, T., Luecke, S., Rannug, U., and Rannug, A. (2012) Inhibition of cytochrome P4501- dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor. Proc. Natl. Acad. Sci. U.S.A., 109, 4479-4484.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 4479-4484
    • Wincent, E.1    Bengtsson, J.2    Mohammadi, B.A.3    Alsberg, T.4    Luecke, S.5    Rannug, U.6    Rannug, A.7
  • 62
    • 84862812389 scopus 로고    scopus 로고
    • A preliminary investigation of unintentional POP emissions from thermal wire reclamation at industrial scrap metal recycling parks in China
    • Nie, Z., Zheng, M., Liu, G., Liu,W., Lv, P., Zhang, B., Su, G., Gao, L., and Xiao, K. (2012) A preliminary investigation of unintentional POP emissions from thermal wire reclamation at industrial scrap metal recycling parks in China. J. Hazard. Mater., 215-216, 259-265.
    • (2012) J. Hazard. Mater. , vol.215-216 , pp. 259-265
    • Nie, Z.1    Zheng, M.2    Liu, G.3    Liu, W.4    Lv, P.5    Zhang, B.6    Su, G.7    Gao, L.8    Xiao, K.9
  • 63
    • 0034653960 scopus 로고    scopus 로고
    • Contaminantinduced immunosuppression and mass mortalities among harbor seals
    • Van, L.H., Ross, P.S., Osterhaus, A.D., and Vos, J.G. (2000) Contaminantinduced immunosuppression and mass mortalities among harbor seals. Toxicol. Lett., 112-113, 319-324.
    • (2000) Toxicol. Lett. , vol.112-113 , pp. 319-324
    • Van, L.H.1    Ross, P.S.2    Osterhaus, A.D.3    Vos, J.G.4
  • 64
    • 0029778102 scopus 로고    scopus 로고
    • Impaired immunity in harbour seals (Phoca vitulina) exposed to bioaccumulated environmental contaminants: review of a long-term feeding study
    • de Swart, R.L., Ross, P.S., Vos, J.G., and Osterhaus, A.D. (1996) Impaired immunity in harbour seals (Phoca vitulina) exposed to bioaccumulated environmental contaminants: review of a long-term feeding study. Environ. Health Perspect., 104 (Suppl. 4), 823-828.
    • (1996) Environ. Health Perspect. , vol.104 , pp. 823-828
    • de Swart, R.L.1    Ross, P.S.2    Vos, J.G.3    Osterhaus, A.D.4
  • 65
    • 0027936546 scopus 로고
    • Alternate immune system targets for TCDD: lymphocyte stem cells and extrathymic T-cell development
    • Silverstone, A.E., Frazier, D.E. Jr., and Gasiewicz, T.A. (1994) Alternate immune system targets for TCDD: lymphocyte stem cells and extrathymic T-cell development. Exp. Clin. Immunogenet., 11, 94-101.
    • (1994) Exp. Clin. Immunogenet. , vol.11 , pp. 94-101
    • Silverstone, A.E.1    Frazier, D.E.2    Gasiewicz, T.A.3
  • 66
    • 0017487917 scopus 로고
    • Immune suppression as related to toxicology
    • Vos, J.G. (1977) Immune suppression as related to toxicology. CRC Crit. Rev. Toxicol., 5, 67-101.
    • (1977) CRC Crit. Rev. Toxicol. , vol.5 , pp. 67-101
    • Vos, J.G.1
  • 67
    • 79952083405 scopus 로고    scopus 로고
    • The long winding road toward understanding the molecular mechanisms for B-cell suppression by 2,3,7,8- tetrachlorodibenzo-p-dioxin
    • Sulentic, C.E. and Kaminski, N.E. (2011) The long winding road toward understanding the molecular mechanisms for B-cell suppression by 2,3,7,8- tetrachlorodibenzo-p-dioxin. Toxicol. Sci., 120 (Suppl. 1), S171-S191.
    • (2011) Toxicol. Sci. , vol.120 , pp. S171-S191
    • Sulentic, C.E.1    Kaminski, N.E.2
  • 68
    • 77953719954 scopus 로고    scopus 로고
    • Functional and phenotypic effects of AhR activation in inflammatory dendritic cells
    • Bankoti, J., Rase, B., Simones, T., and Shepherd, D.M. (2010) Functional and phenotypic effects of AhR activation in inflammatory dendritic cells. Toxicol. Appl. Pharmacol., 246, 18-28.
    • (2010) Toxicol. Appl. Pharmacol. , vol.246 , pp. 18-28
    • Bankoti, J.1    Rase, B.2    Simones, T.3    Shepherd, D.M.4
  • 69
    • 0037340785 scopus 로고    scopus 로고
    • Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antigen-presenting activity of dendritic cells
    • Vorderstrasse, B.A., Dearstyne, E.A., and Kerkvliet, N.I. (2003) Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antigen-presenting activity of dendritic cells. Toxicol. Sci., 72, 103-112.
    • (2003) Toxicol. Sci. , vol.72 , pp. 103-112
    • Vorderstrasse, B.A.1    Dearstyne, E.A.2    Kerkvliet, N.I.3
  • 70
    • 0025005453 scopus 로고
    • Flow cytometric analysis of lymphocyte subpopulations in the spleen and thymus of mice exposed to an acute immunosuppressive dose of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD)
    • Kerkvliet, N.I. and Brauner, J.A. (1990) Flow cytometric analysis of lymphocyte subpopulations in the spleen and thymus of mice exposed to an acute immunosuppressive dose of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD). Environ. Res., 52, 146-154.
    • (1990) Environ. Res. , vol.52 , pp. 146-154
    • Kerkvliet, N.I.1    Brauner, J.A.2
  • 71
    • 0028973341 scopus 로고
    • Evidence for the promotion of positive selection of thymocytes by Ah receptor agonist 2,3,7,8- tetrachlorodibenzo-p-dioxin
    • Kremer, J., Lai, Z.W., and Esser, C. (1995) Evidence for the promotion of positive selection of thymocytes by Ah receptor agonist 2,3,7,8- tetrachlorodibenzo-p-dioxin. Eur. J. Pharmacol., 293, 413-427.
    • (1995) Eur. J. Pharmacol. , vol.293 , pp. 413-427
    • Kremer, J.1    Lai, Z.W.2    Esser, C.3
  • 72
    • 0028031257 scopus 로고
    • Thymic stroma exposed to arylhydrocarbon receptor-binding xenobiotics fails to support proliferation of early thymocytes but induces differentiation
    • Kremer, J., Gleichmann, E., and Esser, C. (1994) Thymic stroma exposed to arylhydrocarbon receptor-binding xenobiotics fails to support proliferation of early thymocytes but induces differentiation. J. Immunol., 153, 2778-2786.
    • (1994) J. Immunol. , vol.153 , pp. 2778-2786
    • Kremer, J.1    Gleichmann, E.2    Esser, C.3
  • 73
  • 74
    • 2942702274 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor diminishes the memory response to homotypic influenza virus infection but does not impair host resistance
    • Lawrence, B.P. and Vorderstrasse, B.A. (2004) Activation of the aryl hydrocarbon receptor diminishes the memory response to homotypic influenza virus infection but does not impair host resistance. Toxicol. Sci., 79, 304-314.
    • (2004) Toxicol. Sci. , vol.79 , pp. 304-314
    • Lawrence, B.P.1    Vorderstrasse, B.A.2
  • 75
    • 79953096181 scopus 로고    scopus 로고
    • Changes in DNA methylation and gene expression during 2,3,7,8-tetrachlorodibenzop- dioxin-induced suppression of the lipopolysaccharide-stimulated IgM response in splenocytes
    • McClure, E.A., North, C.M., Kaminski, N.E., and Goodman, J.I. (2011) Changes in DNA methylation and gene expression during 2,3,7,8-tetrachlorodibenzop- dioxin-induced suppression of the lipopolysaccharide-stimulated IgM response in splenocytes. Toxicol. Sci., 120, 339-348.
    • (2011) Toxicol. Sci. , vol.120 , pp. 339-348
    • McClure, E.A.1    North, C.M.2    Kaminski, N.E.3    Goodman, J.I.4
  • 76
    • 0024998625 scopus 로고
    • Influence of the Ah locus on the humoral immunotoxicity of 2,3,7,8- tetrachlorodibenzo-p-dioxin: evidence for Ah-receptor-dependent and Ahreceptor- independent mechanisms of immunosuppression
    • Kerkvliet, N.I., Steppan, L.B., Brauner, J.A., Deyo, J.A., Henderson, M.C., Tomar, R.S., and Buhler, D.R. (1990) Influence of the Ah locus on the humoral immunotoxicity of 2,3,7,8- tetrachlorodibenzo-p-dioxin: evidence for Ah-receptor-dependent and Ahreceptor- independent mechanisms of immunosuppression. Toxicol. Appl. Pharmacol., 105, 26-36.
    • (1990) Toxicol. Appl. Pharmacol. , vol.105 , pp. 26-36
    • Kerkvliet, N.I.1    Steppan, L.B.2    Brauner, J.A.3    Deyo, J.A.4    Henderson, M.C.5    Tomar, R.S.6    Buhler, D.R.7
  • 77
    • 78751697961 scopus 로고    scopus 로고
    • Consequences of AhR activation in steady-state dendritic cells
    • Simones, T. and Shepherd, D.M. (2011) Consequences of AhR activation in steady-state dendritic cells. Toxicol. Sci., 119, 293-307.
    • (2011) Toxicol. Sci. , vol.119 , pp. 293-307
    • Simones, T.1    Shepherd, D.M.2
  • 79
    • 51649101135 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells
    • Hauben, E., Gregori, S., Draghici, E., Migliavacca, B., Olivieri, S., Woisetschlager, M., and Roncarolo, M.G. (2008) Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells. Blood, 112, 1214-1222.
    • (2008) Blood , vol.112 , pp. 1214-1222
    • Hauben, E.1    Gregori, S.2    Draghici, E.3    Migliavacca, B.4    Olivieri, S.5    Woisetschlager, M.6    Roncarolo, M.G.7
  • 80
    • 0031557129 scopus 로고    scopus 로고
    • The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tumor necrosis factor (TNF) production by peritoneal cells
    • Moos, A.B., Oughton, J.A., and Kerkvliet, N.I. (1997) The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tumor necrosis factor (TNF) production by peritoneal cells. Toxicol. Lett., 90, 145-153.
    • (1997) Toxicol. Lett. , vol.90 , pp. 145-153
    • Moos, A.B.1    Oughton, J.A.2    Kerkvliet, N.I.3
  • 81
    • 0038394478 scopus 로고    scopus 로고
    • Examining the relationship between impaired host resistance and altered immune function in mice treated with TCDD
    • Vorderstrasse, B.A., Bohn, A.A., and Lawrence, B.P. (2003) Examining the relationship between impaired host resistance and altered immune function in mice treated with TCDD. Toxicology, 188, 15-28.
    • (2003) Toxicology , vol.188 , pp. 15-28
    • Vorderstrasse, B.A.1    Bohn, A.A.2    Lawrence, B.P.3
  • 82
    • 39149093670 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor targets pathways extrinsic to bone marrow cells to enhance neutrophil recruitment during influenza virus infection
    • Teske, S., Bohn, A.A., Hogaboam, J.P., and Lawrence, B.P. (2008) Aryl hydrocarbon receptor targets pathways extrinsic to bone marrow cells to enhance neutrophil recruitment during influenza virus infection. Toxicol. Sci., 102, 89-99.
    • (2008) Toxicol. Sci. , vol.102 , pp. 89-99
    • Teske, S.1    Bohn, A.A.2    Hogaboam, J.P.3    Lawrence, B.P.4
  • 83
    • 74549198640 scopus 로고    scopus 로고
    • Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3 T cells in pancreatic lymph nodes
    • Kerkvliet, N.I., Steppan, L.B., Vorachek, W., Oda, S., Farrer, D., Wong, C.P., Pham, D., and Mourich, D.V. (2009) Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3 T cells in pancreatic lymph nodes. Immunotherapy, 1, 539-547.
    • (2009) Immunotherapy , vol.1 , pp. 539-547
    • Kerkvliet, N.I.1    Steppan, L.B.2    Vorachek, W.3    Oda, S.4    Farrer, D.5    Wong, C.P.6    Pham, D.7    Mourich, D.V.8
  • 85
    • 84883203665 scopus 로고    scopus 로고
    • Suppression of Acute Graft-Versus-Host Response by TCDD Is Independent of the CTLA-4-IFNgamma-IDO pathway
    • Rohlman, D., Punj, S., Pennington, J., Bradford, S., and Kerkvliet, N.I. (2013) Suppression of Acute Graft-Versus-Host Response by TCDD Is Independent of the CTLA-4-IFNgamma-IDO pathway. Toxicol. Sci., 135, 81-90.
    • (2013) Toxicol. Sci. , vol.135 , pp. 81-90
    • Rohlman, D.1    Punj, S.2    Pennington, J.3    Bradford, S.4    Kerkvliet, N.I.5
  • 86
    • 77958464034 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin impairs stable establishment of oral tolerance in mice
    • Chmill, S., Kadow, S., Winter, M., Weighardt, H., and Esser, C. (2010) 2,3,7,8-Tetrachlorodibenzo-p-dioxin impairs stable establishment of oral tolerance in mice. Toxicol. Sci., 118, 98-107.
    • (2010) Toxicol. Sci. , vol.118 , pp. 98-107
    • Chmill, S.1    Kadow, S.2    Winter, M.3    Weighardt, H.4    Esser, C.5
  • 87
    • 77955859470 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells
    • Gandhi, R., Kumar, D., Burns, E.J., Nadeau, M., Dake, B., Laroni, A., Kozoriz, D., Weiner, H.L., and Quintana, F.J. (2010) Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Nat. Immunol., 11, 846-853.
    • (2010) Nat. Immunol. , vol.11 , pp. 846-853
    • Gandhi, R.1    Kumar, D.2    Burns, E.J.3    Nadeau, M.4    Dake, B.5    Laroni, A.6    Kozoriz, D.7    Weiner, H.L.8    Quintana, F.J.9
  • 89
    • 84861191696 scopus 로고    scopus 로고
    • Dietary exposure to polychlorinated dibenzo-pdioxins, polychlorinated dibenzofurans and polychlorinated biphenyls of the French population: results of the second French Total Diet Study
    • Sirot, V., Tard, A., Venisseau, A., Brosseaud, A., Marchand, P., Le, B.B., and Leblanc, J.C. (2012) Dietary exposure to polychlorinated dibenzo-pdioxins, polychlorinated dibenzofurans and polychlorinated biphenyls of the French population: results of the second French Total Diet Study. Chemosphere, 88, 492-500.
    • (2012) Chemosphere , vol.88 , pp. 492-500
    • Sirot, V.1    Tard, A.2    Venisseau, A.3    Brosseaud, A.4    Marchand, P.5    Le, B.B.6    Leblanc, J.C.7
  • 90
    • 80555150763 scopus 로고    scopus 로고
    • Levels of PCDD/Fs and DL-PCBs in selected foods and estimated dietary intake for the local residents of Luqiao and Yuhang in Zhejiang, China
    • Song, Y.,Wu, N., Han, J., Shen, H., Tan, Y., Ding, G., Xiang, J., Tao, H., and Jin, S. (2011) Levels of PCDD/Fs and DL-PCBs in selected foods and estimated dietary intake for the local residents of Luqiao and Yuhang in Zhejiang, China. Chemosphere, 85, 329-334.
    • (2011) Chemosphere , vol.85 , pp. 329-334
    • Song, Y.1    Wu, N.2    Han, J.3    Shen, H.4    Tan, Y.5    Ding, G.6    Xiang, J.7    Tao, H.8    Jin, S.9
  • 92
    • 33744987791 scopus 로고    scopus 로고
    • Dioxins and the immune system
    • (ed. H.-W. Vohr), Springer, Heidelberg
    • Esser, C. (2005) Dioxins and the immune system, in Encyclopedic Reference of Immunotoxicology (ed. H.-W. Vohr), Springer, Heidelberg.
    • (2005) Encyclopedic Reference of Immunotoxicology
    • Esser, C.1
  • 93
    • 84866029143 scopus 로고    scopus 로고
    • Biology and function of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference
    • Esser, C. (2012) Biology and function of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference. Arch. Toxicol., 86, 1323-1329.
    • (2012) Arch. Toxicol. , vol.86 , pp. 1323-1329
    • Esser, C.1
  • 94
    • 0037087338 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocytederived dendritic cells
    • Laupeze, B., Amiot, L., Sparfel, L., Le Ferrec, E., Fauchet, R., and Fardel, O. (2002) Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocytederived dendritic cells. J. Immunol., 168, 2652-2658.
    • (2002) J. Immunol. , vol.168 , pp. 2652-2658
    • Laupeze, B.1    Amiot, L.2    Sparfel, L.3    Le Ferrec, E.4    Fauchet, R.5    Fardel, O.6
  • 97
    • 0030015421 scopus 로고    scopus 로고
    • Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development
    • Schmidt, J.V., Su, G.H., Reddy, J.K., Simon, M.C., and Bradfield, C.A. (1996) Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. U.S.A., 93, 6731-6736.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 6731-6736
    • Schmidt, J.V.1    Su, G.H.2    Reddy, J.K.3    Simon, M.C.4    Bradfield, C.A.5
  • 98
    • 66549106623 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor: a perspective on potential roles in the immune system
    • Stevens, E.A., Mezrich, J.D., and Bradfield, C.A. (2009) The aryl hydrocarbon receptor: a perspective on potential roles in the immune system. Immunology, 127, 299-311.
    • (2009) Immunology , vol.127 , pp. 299-311
    • Stevens, E.A.1    Mezrich, J.D.2    Bradfield, C.A.3
  • 99
    • 20844458617 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus
    • Teske, S., Bohn, A.A., Regal, J.F., Neumiller, J.J., and Lawrence, B.P. (2005) Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus. Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L111-L124.
    • (2005) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.289 , pp. L111-L124
    • Teske, S.1    Bohn, A.A.2    Regal, J.F.3    Neumiller, J.J.4    Lawrence, B.P.5
  • 102
    • 38449120554 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is required for optimal resistance to Listeria monocytogenes infection in mice
    • Shi, L.Z., Faith, N.G., Nakayama, Y., Suresh, M., Steinberg, H., and Czuprynski, C.J. (2007) The aryl hydrocarbon receptor is required for optimal resistance to Listeria monocytogenes infection in mice. J. Immunol., 179, 6952-6962.
    • (2007) J. Immunol. , vol.179 , pp. 6952-6962
    • Shi, L.Z.1    Faith, N.G.2    Nakayama, Y.3    Suresh, M.4    Steinberg, H.5    Czuprynski, C.J.6
  • 103
    • 84886092285 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor and experimental autoimmune arthritis
    • Nguyen, N.T., Nakahama, T., and Kishimoto, T. (2013) Aryl hydrocarbon receptor and experimental autoimmune arthritis. Semin. Immunopathol., 35, 637-644.
    • (2013) Semin. Immunopathol. , vol.35 , pp. 637-644
    • Nguyen, N.T.1    Nakahama, T.2    Kishimoto, T.3
  • 104
    • 68949172534 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor and immunity
    • Esser, C., Rannug, A., and Stockinger, B. (2009) The aryl hydrocarbon receptor and immunity. Trends Immunol., 9, 447-454.
    • (2009) Trends Immunol. , vol.9 , pp. 447-454
    • Esser, C.1    Rannug, A.2    Stockinger, B.3
  • 105
    • 60549095448 scopus 로고    scopus 로고
    • Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells
    • Veldhoen, M., Hirota, K., Christensen, J., O'Garra, A., and Stockinger, B. (2009) Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J. Exp. Med., 206, 43-49.
    • (2009) J. Exp. Med. , vol.206 , pp. 43-49
    • Veldhoen, M.1    Hirota, K.2    Christensen, J.3    O'Garra, A.4    Stockinger, B.5
  • 106
    • 47749107262 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells
    • Kimura, A., Naka, T., Nohara, K., Fujii-Kuriyama, Y., and Kishimoto, T. (2008) Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells. Proc. Natl. Acad. Sci. U.S.A., 105, 9721-9726.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 9721-9726
    • Kimura, A.1    Naka, T.2    Nohara, K.3    Fujii-Kuriyama, Y.4    Kishimoto, T.5
  • 107
    • 78649880396 scopus 로고    scopus 로고
    • An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
    • Mezrich, J.D., Fechner, J.H., Zhang, X., Johnson, B.P., Burlingham, W.J., and Bradfield, C.A. (2010) An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. J. Immunol., 185, 3190-3198.
    • (2010) J. Immunol. , vol.185 , pp. 3190-3198
    • Mezrich, J.D.1    Fechner, J.H.2    Zhang, X.3    Johnson, B.P.4    Burlingham, W.J.5    Bradfield, C.A.6
  • 108
    • 75549092188 scopus 로고    scopus 로고
    • Review of murine dendritic cells: types, location, and development
    • Miloud, T., Hammerling, G.J., and Garbi, N. (2010) Review of murine dendritic cells: types, location, and development. Methods Mol. Biol., 595, 21-42.
    • (2010) Methods Mol. Biol. , vol.595 , pp. 21-42
    • Miloud, T.1    Hammerling, G.J.2    Garbi, N.3
  • 109
    • 84893646173 scopus 로고    scopus 로고
    • Dendritic cell subsets in the intestinal lamina propria:ontogeny and function
    • Persson, E.K., Scott, C.L., Mowat, A.M., and Agace, W.W. (2013) Dendritic cell subsets in the intestinal lamina propria:ontogeny and function. Eur. J. Immunol., 43, 3098-30107.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 3098-30107
    • Persson, E.K.1    Scott, C.L.2    Mowat, A.M.3    Agace, W.W.4
  • 110
    • 34547676512 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzop- dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Lee, J.A., Hwang, J.A., Sung, H.N., Jeon, C.H., Gill, B.C., Youn, H.J., and Park, J.H. (2007) 2,3,7,8-Tetrachlorodibenzop- dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Lett., 173, 31-40.
    • (2007) Toxicol. Lett. , vol.173 , pp. 31-40
    • Lee, J.A.1    Hwang, J.A.2    Sung, H.N.3    Jeon, C.H.4    Gill, B.C.5    Youn, H.J.6    Park, J.H.7
  • 111
    • 84865607255 scopus 로고    scopus 로고
    • Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells
    • Vlachos, C., Schulte, B.M., Magiatis, P., Adema, G.J., and Gaitanis, G. (2012) Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells. Br. J. Dermatol., 167, 496-505.
    • (2012) Br. J. Dermatol. , vol.167 , pp. 496-505
    • Vlachos, C.1    Schulte, B.M.2    Magiatis, P.3    Adema, G.J.4    Gaitanis, G.5
  • 112
    • 78650547540 scopus 로고    scopus 로고
    • An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
    • Quintana, F.J., Murugaiyan, G., Farez, M.F., Mitsdoerffer, M., Tukpah, A.M., Burns, E.J., and Weiner, H.L. (2010) An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. U.S.A., 107, 20768-20773.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 20768-20773
    • Quintana, F.J.1    Murugaiyan, G.2    Farez, M.F.3    Mitsdoerffer, M.4    Tukpah, A.M.5    Burns, E.J.6    Weiner, H.L.7
  • 113
    • 77955071099 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection
    • Jin, G.B., Moore, A.J., Head, J.L., Neumiller, J.J., and Lawrence, B.P. (2010) Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection. Toxicol. Sci., 116, 514-522.
    • (2010) Toxicol. Sci. , vol.116 , pp. 514-522
    • Jin, G.B.1    Moore, A.J.2    Head, J.L.3    Neumiller, J.J.4    Lawrence, B.P.5
  • 114
    • 84884165006 scopus 로고    scopus 로고
    • Counterpoise between the microbiome, host immune activation and pathology
    • Mavrommatis, B., Young, G.R., and Kassiotis, G. (2013) Counterpoise between the microbiome, host immune activation and pathology. Curr. Opin. Immunol., 25, 456-462.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 456-462
    • Mavrommatis, B.1    Young, G.R.2    Kassiotis, G.3
  • 115
    • 68649126866 scopus 로고    scopus 로고
    • Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
    • Martin, B., Hirota, K., Cua, D.J., Stockinger, B., and Veldhoen, M. (2009) Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity, 31, 321-330.
    • (2009) Immunity , vol.31 , pp. 321-330
    • Martin, B.1    Hirota, K.2    Cua, D.J.3    Stockinger, B.4    Veldhoen, M.5
  • 118
    • 80053091415 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor is critical for homeostasis of invariant {gamma}{delta} T cells in the murine epidermis
    • Kadow, S., Jux, B., Zahner, S.P., Wingerath, B., Chmill, S., Clausen, B.E., Hengstler, J., and Esser, C. (2011) Aryl hydrocarbon receptor is critical for homeostasis of invariant {gamma}{delta} T cells in the murine epidermis. J. Immunol., 187, 3104-3110.
    • (2011) J. Immunol. , vol.187 , pp. 3104-3110
    • Kadow, S.1    Jux, B.2    Zahner, S.P.3    Wingerath, B.4    Chmill, S.5    Clausen, B.E.6    Hengstler, J.7    Esser, C.8
  • 124
    • 84872191988 scopus 로고    scopus 로고
    • Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection
    • Wheeler, J.L., Martin, K.C., and Lawrence, B.P. (2013) Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection. J. Immunol., 190, 659-668.
    • (2013) J. Immunol. , vol.190 , pp. 659-668
    • Wheeler, J.L.1    Martin, K.C.2    Lawrence, B.P.3
  • 125
    • 84859083851 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis
    • Beamer, C.A., Seaver, B.P., and Shepherd, D.M. (2012) Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis. Toxicol. Sci., 126, 554-568.
    • (2012) Toxicol. Sci. , vol.126 , pp. 554-568
    • Beamer, C.A.1    Seaver, B.P.2    Shepherd, D.M.3
  • 126
    • 79955749457 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions
    • Singh, K.P., Garrett, R.W., Casado, F.L., and Gasiewicz, T.A. (2011) Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions. Stem Cells Dev., 20, 769-784.
    • (2011) Stem Cells Dev. , vol.20 , pp. 769-784
    • Singh, K.P.1    Garrett, R.W.2    Casado, F.L.3    Gasiewicz, T.A.4
  • 127
    • 0034659489 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8- tetrachlorodibenzo-p-dioxin
    • Thurmond, T.S., Staples, J.E., Silverstone, A.E., and Gasiewicz, T.A. (2000) The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8- tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol., 165, 227-236.
    • (2000) Toxicol. Appl. Pharmacol. , vol.165 , pp. 227-236
    • Thurmond, T.S.1    Staples, J.E.2    Silverstone, A.E.3    Gasiewicz, T.A.4
  • 128
    • 84870323656 scopus 로고    scopus 로고
    • The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis
    • Lindsey, S. and Papoutsakis, E.T. (2012) The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis. Stem Cell Rev., 8, 1223-1235.
    • (2012) Stem Cell Rev. , vol.8 , pp. 1223-1235
    • Lindsey, S.1    Papoutsakis, E.T.2


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