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Volumn 77, Issue 4, 2009, Pages 734-745

A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-κB family

Author keywords

AhR; IDO; IL 8; NF kappaB RelB; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; TRANSCRIPTION FACTOR RELB;

EID: 59149104324     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.09.036     Document Type: Article
Times cited : (156)

References (98)
  • 1
    • 0034116376 scopus 로고    scopus 로고
    • The PAS superfamily: sensors of environmental and developmental signals
    • Gu Y.Z., Hogenesch J.B., and Bradfield C.A. The PAS superfamily: sensors of environmental and developmental signals. Ann Rev Pharmacol Toxicol 40 (2000) 519-561
    • (2000) Ann Rev Pharmacol Toxicol , vol.40 , pp. 519-561
    • Gu, Y.Z.1    Hogenesch, J.B.2    Bradfield, C.A.3
  • 2
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison M.S., and Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Ann Rev Pharmacol Toxicol 43 (2003) 309-334
    • (2003) Ann Rev Pharmacol Toxicol , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 3
    • 0023616773 scopus 로고
    • Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances
    • Rannug A., Rannug U., Rosenkranz H.S., Winqvist L., Westerholm R., Agurell E., et al. Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances. J Biol Chem 262 (1987) 15422-15427
    • (1987) J Biol Chem , vol.262 , pp. 15422-15427
    • Rannug, A.1    Rannug, U.2    Rosenkranz, H.S.3    Winqvist, L.4    Westerholm, R.5    Agurell, E.6
  • 4
    • 34547397574 scopus 로고    scopus 로고
    • Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation
    • Fritsche E., Schafer C., Calles C., Bernsmann T., Bernshausen T., Wurm M., et al. Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. Proc Natl Acad Sci USA 104 (2007) 8851-8856
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8851-8856
    • Fritsche, E.1    Schafer, C.2    Calles, C.3    Bernsmann, T.4    Bernshausen, T.5    Wurm, M.6
  • 5
    • 0029949230 scopus 로고    scopus 로고
    • Characterization of the activated form of the aryl hydrocarbon receptor in the nucleus of HeLa cells in the absence of exogenous ligand
    • Singh S.S., Hord N.G., and Perdew G.H. Characterization of the activated form of the aryl hydrocarbon receptor in the nucleus of HeLa cells in the absence of exogenous ligand. Arch Biochem Biophys 329 (1996) 47-55
    • (1996) Arch Biochem Biophys , vol.329 , pp. 47-55
    • Singh, S.S.1    Hord, N.G.2    Perdew, G.H.3
  • 6
    • 1642453873 scopus 로고    scopus 로고
    • Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes
    • Ramadoss P., Petrulis J.R., Hollingshead B.D., Kusnadi A., and Perdew G.H. Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes. Biochemistry 43 (2004) 700-709
    • (2004) Biochemistry , vol.43 , pp. 700-709
    • Ramadoss, P.1    Petrulis, J.R.2    Hollingshead, B.D.3    Kusnadi, A.4    Perdew, G.H.5
  • 7
    • 0034532301 scopus 로고    scopus 로고
    • Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2
    • Petrulis J.R., Hord N.G., and Perdew G.H. Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2. J Biol Chem 275 (2000) 37448-37453
    • (2000) J Biol Chem , vol.275 , pp. 37448-37453
    • Petrulis, J.R.1    Hord, N.G.2    Perdew, G.H.3
  • 8
    • 0142102655 scopus 로고    scopus 로고
    • On the significance of the role of cellular stress response reactions in the toxic actions of dioxin
    • Matsumura F. On the significance of the role of cellular stress response reactions in the toxic actions of dioxin. Biochem Pharmacol 66 (2003) 527-540
    • (2003) Biochem Pharmacol , vol.66 , pp. 527-540
    • Matsumura, F.1
  • 9
    • 59149099857 scopus 로고    scopus 로고
    • National Toxicology Program (U.S.), United States. Dept. of Health and Human Services, United States. Public Health Service, National Institutes of Health (U.S.). NTP technical report on the toxicology and carcinogenesis studies of a mixture of 2,3,7,8-tetrachlorodibenzo- rho -dioxin (TCDD) (CAS no. 1746-01-6), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) (CAS no. 57117-31-4), and 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) (CAS no. 57465-28-8) in female Harlan Sprague-Dawley rats (gavage studies). Research Triangle Park, N.C.: National Toxicology Program National Institutes of Health Public Health Service U.S. Dept. of Health and Human Services, 2006.
    • National Toxicology Program (U.S.), United States. Dept. of Health and Human Services, United States. Public Health Service, National Institutes of Health (U.S.). NTP technical report on the toxicology and carcinogenesis studies of a mixture of 2,3,7,8-tetrachlorodibenzo- rho -dioxin (TCDD) (CAS no. 1746-01-6), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) (CAS no. 57117-31-4), and 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) (CAS no. 57465-28-8) in female Harlan Sprague-Dawley rats (gavage studies). Research Triangle Park, N.C.: National Toxicology Program National Institutes of Health Public Health Service U.S. Dept. of Health and Human Services, 2006.
  • 10
    • 3042598089 scopus 로고    scopus 로고
    • Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds
    • Nyska A., Jokinen M.P., Brix A.E., Sells D.M., Wyde M.E., Orzech D., et al. Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds. Environ Health Perspect 112 (2004) 903-909
    • (2004) Environ Health Perspect , vol.112 , pp. 903-909
    • Nyska, A.1    Jokinen, M.P.2    Brix, A.E.3    Sells, D.M.4    Wyde, M.E.5    Orzech, D.6
  • 11
    • 17844380221 scopus 로고    scopus 로고
    • Aspects of dioxin toxicity are mediated by interleukin 1-like cytokines
    • Pande K., Moran S.M., and Bradfield C.A. Aspects of dioxin toxicity are mediated by interleukin 1-like cytokines. Mol Pharmacol 67 (2005) 1393-1398
    • (2005) Mol Pharmacol , vol.67 , pp. 1393-1398
    • Pande, K.1    Moran, S.M.2    Bradfield, C.A.3
  • 12
    • 0025934316 scopus 로고
    • Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1 beta
    • Sutter T.R., Guzman K., Dold K.M., and Greenlee W.F. Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1 beta. Science 254 (1991) 415-418
    • (1991) Science , vol.254 , pp. 415-418
    • Sutter, T.R.1    Guzman, K.2    Dold, K.M.3    Greenlee, W.F.4
  • 13
    • 0026482969 scopus 로고
    • Inhibition of acute TCDD toxicity by treatment with anti-tumor necrosis factor antibody or dexamethasone
    • Taylor M.J., Lucier G.W., Mahler J.F., Thompson M., Lockhart A.C., and Clark G.C. Inhibition of acute TCDD toxicity by treatment with anti-tumor necrosis factor antibody or dexamethasone. Toxicol Appl Pharmacol 117 (1992) 126-132
    • (1992) Toxicol Appl Pharmacol , vol.117 , pp. 126-132
    • Taylor, M.J.1    Lucier, G.W.2    Mahler, J.F.3    Thompson, M.4    Lockhart, A.C.5    Clark, G.C.6
  • 14
    • 0030614910 scopus 로고    scopus 로고
    • Cytokines (IL-1beta and TNFalpha) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats
    • Fan F., Yan B., Wood G., Viluksela M., and Rozman K.K. Cytokines (IL-1beta and TNFalpha) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats. Toxicology 116 (1997) 9-16
    • (1997) Toxicology , vol.116 , pp. 9-16
    • Fan, F.1    Yan, B.2    Wood, G.3    Viluksela, M.4    Rozman, K.K.5
  • 15
    • 0032520752 scopus 로고    scopus 로고
    • Modulation of prostaglandin H synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice
    • Vogel C., Schuhmacher U.S., Degen G.H., Bolt H.M., Pineau T., and Abel J. Modulation of prostaglandin H synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice. Arch Biochem Biophys 351 (1998) 265-271
    • (1998) Arch Biochem Biophys , vol.351 , pp. 265-271
    • Vogel, C.1    Schuhmacher, U.S.2    Degen, G.H.3    Bolt, H.M.4    Pineau, T.5    Abel, J.6
  • 16
    • 33748741806 scopus 로고    scopus 로고
    • Evidence supporting the hypothesis that one of the main functions of the aryl hydrocarbon receptor is mediation of cell stress responses
    • Matsumura F., and Vogel C.F. Evidence supporting the hypothesis that one of the main functions of the aryl hydrocarbon receptor is mediation of cell stress responses. Biol Chem 387 (2006) 1189-1194
    • (2006) Biol Chem , vol.387 , pp. 1189-1194
    • Matsumura, F.1    Vogel, C.F.2
  • 17
    • 34247572978 scopus 로고    scopus 로고
    • Modulation of the chemokines KC and MCP-1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice
    • Vogel C.F., Nishimura N., Sciullo E., Wong P., Li W., and Matsumura F. Modulation of the chemokines KC and MCP-1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice. Arch Biochem Biophys 461 (2007) 169-175
    • (2007) Arch Biochem Biophys , vol.461 , pp. 169-175
    • Vogel, C.F.1    Nishimura, N.2    Sciullo, E.3    Wong, P.4    Li, W.5    Matsumura, F.6
  • 18
  • 19
    • 27744507582 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines and C-reactive protein in human macrophage cell line U937 exposed to air pollution particulates
    • Vogel C.F., Sciullo E., Wong P., Kuzmicky P., Kado N., and Matsumura F. Induction of proinflammatory cytokines and C-reactive protein in human macrophage cell line U937 exposed to air pollution particulates. Env Health Perspect 113 (2005) 1536-1541
    • (2005) Env Health Perspect , vol.113 , pp. 1536-1541
    • Vogel, C.F.1    Sciullo, E.2    Wong, P.3    Kuzmicky, P.4    Kado, N.5    Matsumura, F.6
  • 20
    • 0034829818 scopus 로고    scopus 로고
    • Chemokines in pathology and medicine
    • Baggiolini M. Chemokines in pathology and medicine. J Intern Med 250 (2001) 91-104
    • (2001) J Intern Med , vol.250 , pp. 91-104
    • Baggiolini, M.1
  • 21
    • 0027458138 scopus 로고
    • The AH-receptor: genetics, structure and function
    • Swanson H.I., and Bradfield C.A. The AH-receptor: genetics, structure and function. Pharmacogenetics 3 (1993) 213-230
    • (1993) Pharmacogenetics , vol.3 , pp. 213-230
    • Swanson, H.I.1    Bradfield, C.A.2
  • 22
    • 0034087885 scopus 로고    scopus 로고
    • Mechanistic aspects-the dioxin (aryl hydrocarbon) receptor
    • Poellinger L. Mechanistic aspects-the dioxin (aryl hydrocarbon) receptor. Food Add Contam 17 (2000) 261-266
    • (2000) Food Add Contam , vol.17 , pp. 261-266
    • Poellinger, L.1
  • 23
    • 12244275029 scopus 로고    scopus 로고
    • A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins
    • Carlson D.B., and Perdew G.H. A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins. J Biochem Mol Toxicol 16 (2002) 317-325
    • (2002) J Biochem Mol Toxicol , vol.16 , pp. 317-325
    • Carlson, D.B.1    Perdew, G.H.2
  • 24
    • 9944255780 scopus 로고    scopus 로고
    • Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor
    • Hankinson O. Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor. Arch Biochem Biophys 433 (2005) 379-386
    • (2005) Arch Biochem Biophys , vol.433 , pp. 379-386
    • Hankinson, O.1
  • 25
    • 0032575589 scopus 로고    scopus 로고
    • A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
    • Ge N.L., and Elferink C.J. A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J Biol Chem 273 (1998) 22708-22713
    • (1998) J Biol Chem , vol.273 , pp. 22708-22713
    • Ge, N.L.1    Elferink, C.J.2
  • 26
    • 0032957695 scopus 로고    scopus 로고
    • Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity
    • Tian Y., Ke S., Denison M.S., Rabson A.B., and Gallo M.A. Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity. J Biol Chem 274 (1999) 510-515
    • (1999) J Biol Chem , vol.274 , pp. 510-515
    • Tian, Y.1    Ke, S.2    Denison, M.S.3    Rabson, A.B.4    Gallo, M.A.5
  • 27
    • 0033958620 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1
    • Klinge C.M., Kaur K., and Swanson H.I. The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1. Arch Biochem Biophys 373 (2000) 163-174
    • (2000) Arch Biochem Biophys , vol.373 , pp. 163-174
    • Klinge, C.M.1    Kaur, K.2    Swanson, H.I.3
  • 28
    • 0038100188 scopus 로고    scopus 로고
    • Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
    • Ohtake F., Takeyama K., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., et al. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423 (2003) 545-550
    • (2003) Nature , vol.423 , pp. 545-550
    • Ohtake, F.1    Takeyama, K.2    Matsumoto, T.3    Kitagawa, H.4    Yamamoto, Y.5    Nohara, K.6
  • 29
    • 34848920850 scopus 로고    scopus 로고
    • Involvement of RelB in aryl hydrocarbon receptor-mediated induction of chemokines
    • Vogel C.F., Sciullo E., and Matsumura F. Involvement of RelB in aryl hydrocarbon receptor-mediated induction of chemokines. Biochem Biophys Res Commun 363 (2007) 722-726
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 722-726
    • Vogel, C.F.1    Sciullo, E.2    Matsumura, F.3
  • 30
    • 54249157595 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis
    • Marlowe J.L., Fan Y., Chang X., Peng L., Knudsen E.S., Xia Y., et al. The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis. Mol Biol Cell 19 (2008) 3263-3271
    • (2008) Mol Biol Cell , vol.19 , pp. 3263-3271
    • Marlowe, J.L.1    Fan, Y.2    Chang, X.3    Peng, L.4    Knudsen, E.S.5    Xia, Y.6
  • 31
    • 0032447116 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor: studies using the AHR-null mice
    • Gonzalez F.J., and Fernandez-Salguero P. The aryl hydrocarbon receptor: studies using the AHR-null mice. Drug Metabol Dispos 26 (1998) 1194-1198
    • (1998) Drug Metabol Dispos , vol.26 , pp. 1194-1198
    • Gonzalez, F.J.1    Fernandez-Salguero, P.2
  • 32
    • 14944374033 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse
    • Lahvis G.P., Pyzalski R.W., Glover E., Pitot H.C., McElwee M.K., and Bradfield C.A. The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse. Mol Pharmacol 67 (2005) 714-720
    • (2005) Mol Pharmacol , vol.67 , pp. 714-720
    • Lahvis, G.P.1    Pyzalski, R.W.2    Glover, E.3    Pitot, H.C.4    McElwee, M.K.5    Bradfield, C.A.6
  • 33
    • 0942265563 scopus 로고    scopus 로고
    • Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice
    • Andreola F., Hayhurst G.P., Luo G., Ferguson S.S., Gonzalez F.J., Goldstein J.A., et al. Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice. J Biol Chem 279 (2004) 3434-3438
    • (2004) J Biol Chem , vol.279 , pp. 3434-3438
    • Andreola, F.1    Hayhurst, G.P.2    Luo, G.3    Ferguson, S.S.4    Gonzalez, F.J.5    Goldstein, J.A.6
  • 35
    • 0029000839 scopus 로고
    • Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
    • Fernandez-Salguero P., Pineau T., Hilbert D.M., McPhail T., Lee S.S., Kimura S., et al. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science 268 (1995) 722-726
    • (1995) Science , vol.268 , pp. 722-726
    • Fernandez-Salguero, P.1    Pineau, T.2    Hilbert, D.M.3    McPhail, T.4    Lee, S.S.5    Kimura, S.6
  • 36
    • 1942501666 scopus 로고    scopus 로고
    • Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele T
    • Walisser J.A., Bunger M.K., Glover E., Harstad E.B., and Bradfield C.A. Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele T. J Biol Chem 279 (2004) 16326-16331
    • (2004) J Biol Chem , vol.279 , pp. 16326-16331
    • Walisser, J.A.1    Bunger, M.K.2    Glover, E.3    Harstad, E.B.4    Bradfield, C.A.5
  • 37
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • Quintana F.J., Basso A.S., Iglesias A.H., Korn T., Farez M.F., Bettelli E., et al. Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature 453 (2008) 65-71
    • (2008) Nature , vol.453 , pp. 65-71
    • Quintana, F.J.1    Basso, A.S.2    Iglesias, A.H.3    Korn, T.4    Farez, M.F.5    Bettelli, E.6
  • 38
    • 42649106556 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
    • Veldhoen M., Hirota K., Westendorf A.M., Buer J., Dumoutier L., Renauld J.C., et al. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 453 (2008) 106-109
    • (2008) Nature , vol.453 , pp. 106-109
    • Veldhoen, M.1    Hirota, K.2    Westendorf, A.M.3    Buer, J.4    Dumoutier, L.5    Renauld, J.C.6
  • 40
    • 41149083510 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T cells toward a regulatory T cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T cells
    • Funatake C.J., Marshall N.B., and Kerkvliet N.I. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T cells toward a regulatory T cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T cells. J Immunotoxicol 5 (2008) 81-91
    • (2008) J Immunotoxicol , vol.5 , pp. 81-91
    • Funatake, C.J.1    Marshall, N.B.2    Kerkvliet, N.I.3
  • 41
    • 25444526629 scopus 로고    scopus 로고
    • Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells
    • Funatake C.J., Marshall N.B., Steppan L.B., Mourich D.V., and Kerkvliet N.I. Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells. J Immunol 175 (2005) 4184-4188
    • (2005) J Immunol , vol.175 , pp. 4184-4188
    • Funatake, C.J.1    Marshall, N.B.2    Steppan, L.B.3    Mourich, D.V.4    Kerkvliet, N.I.5
  • 42
    • 50949098849 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase
    • Vogel C.F., Goth S.R., Dong B., Pessah I.N., and Matsumura F. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun 375 (2008) 331-335
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 331-335
    • Vogel, C.F.1    Goth, S.R.2    Dong, B.3    Pessah, I.N.4    Matsumura, F.5
  • 43
    • 0032556894 scopus 로고    scopus 로고
    • Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
    • Chen F.E., Huang D.B., Chen Y.Q., and Ghosh G. Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature 391 (1998) 410-413
    • (1998) Nature , vol.391 , pp. 410-413
    • Chen, F.E.1    Huang, D.B.2    Chen, Y.Q.3    Ghosh, G.4
  • 44
    • 0026774239 scopus 로고
    • Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation
    • Kunsch C., Ruben S.M., and Rosen C.A. Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation. Mol Cell Biol 12 (1992) 4412-4421
    • (1992) Mol Cell Biol , vol.12 , pp. 4412-4421
    • Kunsch, C.1    Ruben, S.M.2    Rosen, C.A.3
  • 45
    • 33749265867 scopus 로고    scopus 로고
    • The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development
    • Dejardin E. The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem Pharmacol 72 (2006) 1161-1179
    • (2006) Biochem Pharmacol , vol.72 , pp. 1161-1179
    • Dejardin, E.1
  • 46
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
    • Dejardin E., Droin N.M., Delhase M., Haas E., Cao Y., Makris C., et al. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 17 (2002) 525-535
    • (2002) Immunity , vol.17 , pp. 525-535
    • Dejardin, E.1    Droin, N.M.2    Delhase, M.3    Haas, E.4    Cao, Y.5    Makris, C.6
  • 47
    • 9144275033 scopus 로고    scopus 로고
    • Activation of IK{cyrillic}K{cyrillic}alpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
    • Bonizzi G., Bebien M., Otero D.C., Johnson-Vroom K.E., Cao Y., Vu D., et al. Activation of IK{cyrillic}K{cyrillic}alpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO 23 (2004) 4202-4210
    • (2004) EMBO , vol.23 , pp. 4202-4210
    • Bonizzi, G.1    Bebien, M.2    Otero, D.C.3    Johnson-Vroom, K.E.4    Cao, Y.5    Vu, D.6
  • 49
    • 44749088134 scopus 로고    scopus 로고
    • Crosstalk via the NF-kappaB signaling system
    • Basak S., and Hoffmann A. Crosstalk via the NF-kappaB signaling system. Cytokine Growth Factor Rev 19 (2008) 187-197
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 187-197
    • Basak, S.1    Hoffmann, A.2
  • 50
    • 33846323310 scopus 로고    scopus 로고
    • A fourth IkappaB protein within the NF-kappaB signaling module
    • Basak S., Kim H., Kearns J.D., Tergaonkar V., O'Dea E., Werner S.L., et al. A fourth IkappaB protein within the NF-kappaB signaling module. Cell 128 (2007) 369-381
    • (2007) Cell , vol.128 , pp. 369-381
    • Basak, S.1    Kim, H.2    Kearns, J.D.3    Tergaonkar, V.4    O'Dea, E.5    Werner, S.L.6
  • 51
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family
    • Weih F., Carrasco D., Durham S.K., Barton D.S., Rizzo C.A., Ryseck R.P., et al. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell 80 (1995) 331-340
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6
  • 52
    • 0028952482 scopus 로고
    • Expression of relB is required for the development of thymic medulla and dendritic cells
    • Burkly L., Hession C., Ogata L., Reilly C., Marconi L.A., Olson D., et al. Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373 (1995) 531-536
    • (1995) Nature , vol.373 , pp. 531-536
    • Burkly, L.1    Hession, C.2    Ogata, L.3    Reilly, C.4    Marconi, L.A.5    Olson, D.6
  • 53
    • 23844451425 scopus 로고    scopus 로고
    • Regulation of RelB expression during the initiation of dendritic cell differentiation
    • Cejas P.J., Carlson L.M., Kolonias D., Zhang J., Lindner I., Billadeau D.D., et al. Regulation of RelB expression during the initiation of dendritic cell differentiation. Mol Cell Biol 25 (2005) 7900-7916
    • (2005) Mol Cell Biol , vol.25 , pp. 7900-7916
    • Cejas, P.J.1    Carlson, L.M.2    Kolonias, D.3    Zhang, J.4    Lindner, I.5    Billadeau, D.D.6
  • 54
    • 18544364477 scopus 로고    scopus 로고
    • Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
    • Munn D.H., Sharma M.D., Lee J.R., Jhaver K.G., Johnson T.S., Keskin D.B., et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 297 (2002) 1867-1870
    • (2002) Science , vol.297 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3    Jhaver, K.G.4    Johnson, T.S.5    Keskin, D.B.6
  • 55
    • 34548863106 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation
    • Tas S.W., Vervoordeldonk M.J., Hajji N., Schuitemaker J.H., van der Sluijs K.F., May M.J., et al. Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. Blood 110 (2007) 1540-1549
    • (2007) Blood , vol.110 , pp. 1540-1549
    • Tas, S.W.1    Vervoordeldonk, M.J.2    Hajji, N.3    Schuitemaker, J.H.4    van der Sluijs, K.F.5    May, M.J.6
  • 56
    • 33947586159 scopus 로고    scopus 로고
    • Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications
    • Jost P.J., and Ruland J. Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications. Blood 109 (2007) 2700-2707
    • (2007) Blood , vol.109 , pp. 2700-2707
    • Jost, P.J.1    Ruland, J.2
  • 57
    • 33745852665 scopus 로고    scopus 로고
    • Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease
    • Xiao G., Rabson A.B., Young W., Qing G., and Qu Z. Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease. Cytokine Growth Factor Rev 17 (2006) 281-293
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 281-293
    • Xiao, G.1    Rabson, A.B.2    Young, W.3    Qing, G.4    Qu, Z.5
  • 58
    • 34547138171 scopus 로고    scopus 로고
    • NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis
    • Zhang B., Wang Z., Li T., Tsitsikov E.N., and Ding H.F. NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood 110 (2007) 743-751
    • (2007) Blood , vol.110 , pp. 743-751
    • Zhang, B.1    Wang, Z.2    Li, T.3    Tsitsikov, E.N.4    Ding, H.F.5
  • 59
    • 36348988444 scopus 로고    scopus 로고
    • Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression
    • Vogel C.F., Li W., Sciullo E., Newman J., Hammock B., Reader J.R., et al. Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression. Am J Pathol 171 (2007) 1538-1548
    • (2007) Am J Pathol , vol.171 , pp. 1538-1548
    • Vogel, C.F.1    Li, W.2    Sciullo, E.3    Newman, J.4    Hammock, B.5    Reader, J.R.6
  • 60
    • 34047095373 scopus 로고    scopus 로고
    • Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2
    • Wang X., Belguise K., Kersual N., Kirsch K.H., Mineva N.D., Galtier F., et al. Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2. Nat Cell Biol 9 (2007) 470-478
    • (2007) Nat Cell Biol , vol.9 , pp. 470-478
    • Wang, X.1    Belguise, K.2    Kersual, N.3    Kirsch, K.H.4    Mineva, N.D.5    Galtier, F.6
  • 61
    • 0031440245 scopus 로고    scopus 로고
    • Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer
    • Sovak M.A., Bellas R.E., Kim D.W., Zanieski G.J., Rogers A.E., Traish A.M., et al. Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer. J Clin Invest 100 (1997) 2952-2960
    • (1997) J Clin Invest , vol.100 , pp. 2952-2960
    • Sovak, M.A.1    Bellas, R.E.2    Kim, D.W.3    Zanieski, G.J.4    Rogers, A.E.5    Traish, A.M.6
  • 62
    • 34548299550 scopus 로고    scopus 로고
    • NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation
    • Van Laere S.J., Van der Auwera I., Van den Eynden G.G., van Dam P., Van Marck E.A., Vermeulen P.B., et al. NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation. Br J Cancer 97 (2007) 659-669
    • (2007) Br J Cancer , vol.97 , pp. 659-669
    • Van Laere, S.J.1    Van der Auwera, I.2    Van den Eynden, G.G.3    van Dam, P.4    Van Marck, E.A.5    Vermeulen, P.B.6
  • 63
    • 27644466358 scopus 로고    scopus 로고
    • Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study
    • Lessard L., Begin L.R., Gleave M.E., Mes-Masson A.M., and Saad F. Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study. Br J Cancer 93 (2005) 1019-1023
    • (2005) Br J Cancer , vol.93 , pp. 1019-1023
    • Lessard, L.1    Begin, L.R.2    Gleave, M.E.3    Mes-Masson, A.M.4    Saad, F.5
  • 64
    • 33745213966 scopus 로고    scopus 로고
    • Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding
    • Van Laere S.J., Van der Auwera I., Van den Eynden G.G., Elst H.J., Weyler J., Harris A.L., et al. Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding. Clin Cancer Res 12 (2006) 3249-3256
    • (2006) Clin Cancer Res , vol.12 , pp. 3249-3256
    • Van Laere, S.J.1    Van der Auwera, I.2    Van den Eynden, G.G.3    Elst, H.J.4    Weyler, J.5    Harris, A.L.6
  • 65
    • 33845910163 scopus 로고    scopus 로고
    • NFkappaB1/p50 is not required for tumor necrosis factor-stimulated growth of primary mammary epithelial cells: implications for NFkappaB2/p52 and RelB
    • Zhang J., Warren M.A., Shoemaker S.F., and Ip M.M. NFkappaB1/p50 is not required for tumor necrosis factor-stimulated growth of primary mammary epithelial cells: implications for NFkappaB2/p52 and RelB. Endocrinol 148 (2007) 268-278
    • (2007) Endocrinol , vol.148 , pp. 268-278
    • Zhang, J.1    Warren, M.A.2    Shoemaker, S.F.3    Ip, M.M.4
  • 66
    • 40549086961 scopus 로고    scopus 로고
    • Estrogenic status modulates aryl hydrocarbon receptor-mediated hepatic gene expression and carcinogenicity
    • Singhal R., Shankar K., Badger T.M., and Ronis M.J. Estrogenic status modulates aryl hydrocarbon receptor-mediated hepatic gene expression and carcinogenicity. Carcinogenesis 29 (2008) 227-236
    • (2008) Carcinogenesis , vol.29 , pp. 227-236
    • Singhal, R.1    Shankar, K.2    Badger, T.M.3    Ronis, M.J.4
  • 68
    • 36148932553 scopus 로고    scopus 로고
    • Chemokines: novel targets for breast cancer metastasis
    • Ali S., and Lazennec G. Chemokines: novel targets for breast cancer metastasis. Cancer Metastasis Rev 26 (2007) 401-420
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 401-420
    • Ali, S.1    Lazennec, G.2
  • 69
    • 4444342957 scopus 로고    scopus 로고
    • Mechanisms underlying differential expression of interleukin-8 in breast cancer cells
    • Freund A., Jolivel V., Durand S., Kersual N., Chalbos D., Chavey C., et al. Mechanisms underlying differential expression of interleukin-8 in breast cancer cells. Oncogene 23 (2004) 6105-6114
    • (2004) Oncogene , vol.23 , pp. 6105-6114
    • Freund, A.1    Jolivel, V.2    Durand, S.3    Kersual, N.4    Chalbos, D.5    Chavey, C.6
  • 71
    • 44349127443 scopus 로고    scopus 로고
    • Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8
    • Wu K., Katiyar S., Li A., Liu M., Ju X., Popov V.M., et al. Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proc Natl Acad Sci USA 105 (2008) 6924-6929
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6924-6929
    • Wu, K.1    Katiyar, S.2    Li, A.3    Liu, M.4    Ju, X.5    Popov, V.M.6
  • 72
    • 34247857744 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB
    • Thatcher T.H., Maggirwar S.B., Baglole C.J., Lakatos H.F., Gasiewicz T.A., Phipps R.P., et al. Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB. Am J Pathol 170 (2007) 855-864
    • (2007) Am J Pathol , vol.170 , pp. 855-864
    • Thatcher, T.H.1    Maggirwar, S.B.2    Baglole, C.J.3    Lakatos, H.F.4    Gasiewicz, T.A.5    Phipps, R.P.6
  • 73
    • 0142091390 scopus 로고    scopus 로고
    • Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells
    • Iourgenko V., Zhang W., Mickanin C., Daly I., Jiang C., Hexham J.M., et al. Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci USA 100 (2003) 12147-12152
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12147-12152
    • Iourgenko, V.1    Zhang, W.2    Mickanin, C.3    Daly, I.4    Jiang, C.5    Hexham, J.M.6
  • 75
    • 34250346920 scopus 로고    scopus 로고
    • Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor
    • de Oliveira S.K., Hoffmeister M., Gambaryan S., Müller-Esterl W., Guimaraes J.A., and Smolenski A.P. Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor. J Biol Chem. 282 (2007) 13656-13663
    • (2007) J Biol Chem. , vol.282 , pp. 13656-13663
    • de Oliveira, S.K.1    Hoffmeister, M.2    Gambaryan, S.3    Müller-Esterl, W.4    Guimaraes, J.A.5    Smolenski, A.P.6
  • 76
    • 54349090870 scopus 로고    scopus 로고
    • Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA binding domain of the aryl hydrocarbon receptor
    • Bunger M.K., Glover E., Moran S.M., Walisser J.A., Lahvis G.P., Hsu E.L., et al. Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA binding domain of the aryl hydrocarbon receptor. Toxicol Sci (2008)
    • (2008) Toxicol Sci
    • Bunger, M.K.1    Glover, E.2    Moran, S.M.3    Walisser, J.A.4    Lahvis, G.P.5    Hsu, E.L.6
  • 77
    • 38649085672 scopus 로고    scopus 로고
    • Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD
    • Li W., Vogel C.F., Fujiyoshi P., and Matsumura F. Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD. Biol Chem 389 (2008) 169-177
    • (2008) Biol Chem , vol.389 , pp. 169-177
    • Li, W.1    Vogel, C.F.2    Fujiyoshi, P.3    Matsumura, F.4
  • 78
    • 0034521528 scopus 로고    scopus 로고
    • Regulation of prostaglandin endoperoxide H synthase-2 induction by dioxin in rat hepatocytes: possible c-Src-mediated pathway
    • Vogel C., Boerboom A.M., Baechle C., El-Bahay C., Kahl R., Degen G.H., et al. Regulation of prostaglandin endoperoxide H synthase-2 induction by dioxin in rat hepatocytes: possible c-Src-mediated pathway. Carcinogenesis 21 (2000) 2267-2274
    • (2000) Carcinogenesis , vol.21 , pp. 2267-2274
    • Vogel, C.1    Boerboom, A.M.2    Baechle, C.3    El-Bahay, C.4    Kahl, R.5    Degen, G.H.6
  • 79
    • 57649215587 scopus 로고    scopus 로고
    • Baglole CJ, Maggirwar SB, Gasiewicz TA, Thatcher TH, Phipps RP, Sime PJ. The aryl hydrocarbon receptor attenuates tobacco smoke induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappa B family member RELB. J Biol Chem 2008 Aug 12 [Epub ahead of print].
    • Baglole CJ, Maggirwar SB, Gasiewicz TA, Thatcher TH, Phipps RP, Sime PJ. The aryl hydrocarbon receptor attenuates tobacco smoke induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappa B family member RELB. J Biol Chem 2008 Aug 12 [Epub ahead of print].
  • 80
    • 23944517220 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts
    • Martey C.A., Baglole C.J., Gasiewicz T.A., Sime P.J., and Phipps R.P. The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 289 Sep (3) (2005) L391-L399
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.289 , Issue.Sep 3
    • Martey, C.A.1    Baglole, C.J.2    Gasiewicz, T.A.3    Sime, P.J.4    Phipps, R.P.5
  • 81
    • 34547676512 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Lee J.A., Hwang J.A., Sung H.N., Jeon C.H., Gill B.C., Youn H.J., et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Lett 173 (2007) 31-40
    • (2007) Toxicol Lett , vol.173 , pp. 31-40
    • Lee, J.A.1    Hwang, J.A.2    Sung, H.N.3    Jeon, C.H.4    Gill, B.C.5    Youn, H.J.6
  • 82
    • 0036147662 scopus 로고    scopus 로고
    • Recent advances in understanding the mechanisms of TCDD immunotoxicity
    • Kerkvliet N.I. Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int Immunopharmacol 2 (2002) 277-291
    • (2002) Int Immunopharmacol , vol.2 , pp. 277-291
    • Kerkvliet, N.I.1
  • 83
    • 51649101135 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor promotes allograft specific tolerance through direct- and DC-mediated effects on regulatory T cells
    • Hauben E., Gregori S., Draghici E., Migliavacca B., Olivieri S., Woisetschlager M., et al. Activation of the aryl hydrocarbon receptor promotes allograft specific tolerance through direct- and DC-mediated effects on regulatory T cells. Blood (2008)
    • (2008) Blood
    • Hauben, E.1    Gregori, S.2    Draghici, E.3    Migliavacca, B.4    Olivieri, S.5    Woisetschlager, M.6
  • 84
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance
    • Steinman R.M., and Nussenzweig M.C. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci USA 99 (2002) 351-358
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 85
    • 34547894233 scopus 로고    scopus 로고
    • Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation
    • Mahnke K., Ring S., Johnson T.S., Schallenberg S., Schonfeld K., Storn V., et al. Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation. Euro J Immunol 37 (2007) 2117-2126
    • (2007) Euro J Immunol , vol.37 , pp. 2117-2126
    • Mahnke, K.1    Ring, S.2    Johnson, T.S.3    Schallenberg, S.4    Schonfeld, K.5    Storn, V.6
  • 86
    • 0037340785 scopus 로고    scopus 로고
    • Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antigen-presenting activity of dendritic cells
    • Vorderstrasse B.A., Dearstyne E.A., and Kerkvliet N.I. Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antigen-presenting activity of dendritic cells. Toxicol Sci 72 (2003) 103-112
    • (2003) Toxicol Sci , vol.72 , pp. 103-112
    • Vorderstrasse, B.A.1    Dearstyne, E.A.2    Kerkvliet, N.I.3
  • 87
    • 0035282330 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules
    • Vorderstrasse B.A., and Kerkvliet N.I. 2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules. Toxicol Appl Pharmacol 171 (2001) 117-125
    • (2001) Toxicol Appl Pharmacol , vol.171 , pp. 117-125
    • Vorderstrasse, B.A.1    Kerkvliet, N.I.2
  • 88
    • 0036765531 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-alpha and anti-CD40-induced activation of NF-kappaB/Rel in dendritic cells: p50 homodimer activation is not affected
    • Ruby C.E., Leid M., and Kerkvliet N.I. 2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-alpha and anti-CD40-induced activation of NF-kappaB/Rel in dendritic cells: p50 homodimer activation is not affected. Mol Pharmacol 62 (2002) 722-728
    • (2002) Mol Pharmacol , vol.62 , pp. 722-728
    • Ruby, C.E.1    Leid, M.2    Kerkvliet, N.I.3
  • 89
    • 49449095646 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound
    • Lawrence B.P., Denison M.S., Novak H., Vorderstrasse B.A., Harrer N., Neruda W., Reichel C., and Woisetschläger M. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood 112 Aug (4) (2008) 1158-1165
    • (2008) Blood , vol.112 , Issue.Aug 4 , pp. 1158-1165
    • Lawrence, B.P.1    Denison, M.S.2    Novak, H.3    Vorderstrasse, B.A.4    Harrer, N.5    Neruda, W.6    Reichel, C.7    Woisetschläger, M.8
  • 90
    • 2942741978 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AhR) agonists suppress interleukin-6 expression by bone marrow stromal cells: an immunotoxicology study
    • Jensen B.A., Leeman R.J., Schlezinger J.J., and Sherr D.H. Aryl hydrocarbon receptor (AhR) agonists suppress interleukin-6 expression by bone marrow stromal cells: an immunotoxicology study. Environ Health 2 1 (Dec 16 2003) 16
    • (2003) Environ Health , vol.2 , Issue.1 , pp. 16
    • Jensen, B.A.1    Leeman, R.J.2    Schlezinger, J.J.3    Sherr, D.H.4
  • 91
    • 0034676269 scopus 로고    scopus 로고
    • The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells
    • Kim D.W., Gazourian L., Quadri S.A., Romieu-Mourez R., Sherr D.H., and Sonenshein G.E. The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 48 (2000) 5498-5506
    • (2000) Oncogene , vol.48 , pp. 5498-5506
    • Kim, D.W.1    Gazourian, L.2    Quadri, S.A.3    Romieu-Mourez, R.4    Sherr, D.H.5    Sonenshein, G.E.6
  • 92
    • 0030762656 scopus 로고    scopus 로고
    • RelB regulation of chemokine expression modulates local inflammation
    • Xia Y., Pauza M.E., Feng L., and Lo D. RelB regulation of chemokine expression modulates local inflammation. Am J Pathol 151 (1997) 375-387
    • (1997) Am J Pathol , vol.151 , pp. 375-387
    • Xia, Y.1    Pauza, M.E.2    Feng, L.3    Lo, D.4
  • 93
    • 43049086657 scopus 로고    scopus 로고
    • Nuclear factor-kappaB1: regulation and function
    • Pereira S.G., and Oakley F. Nuclear factor-kappaB1: regulation and function. Int J Biochem Cell Biol 40 (2008) 1425-1430
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1425-1430
    • Pereira, S.G.1    Oakley, F.2
  • 94
    • 17844386319 scopus 로고    scopus 로고
    • IK{cyrillic}K{cyrillic}alpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
    • Lawrence T., Bebien M., Liu G.Y., Nizet V., and Karin M. IK{cyrillic}K{cyrillic}alpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 434 (2005) 1138-1143
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 95
    • 33744965194 scopus 로고    scopus 로고
    • Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells
    • Matos P., and Jordan P. Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells. J Biol Chem 281 (2006) 13724-13732
    • (2006) J Biol Chem , vol.281 , pp. 13724-13732
    • Matos, P.1    Jordan, P.2
  • 96
    • 33644837287 scopus 로고    scopus 로고
    • RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells
    • Josson S., Xu Y., Fang F., Dhar S.K., St Clair D.K., and St Clair W.H. RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells. Oncogene 25 (2006) 1554-1559
    • (2006) Oncogene , vol.25 , pp. 1554-1559
    • Josson, S.1    Xu, Y.2    Fang, F.3    Dhar, S.K.4    St Clair, D.K.5    St Clair, W.H.6
  • 97
    • 34250788040 scopus 로고    scopus 로고
    • Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells
    • Lwin T., Hazlehurst L.A., Li Z., Dessureault S., Sotomayor E., Moscinski L.C., et al. Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells. Leukemia 21 (2007) 1521-1531
    • (2007) Leukemia , vol.21 , pp. 1521-1531
    • Lwin, T.1    Hazlehurst, L.A.2    Li, Z.3    Dessureault, S.4    Sotomayor, E.5    Moscinski, L.C.6
  • 98
    • 33644542403 scopus 로고    scopus 로고
    • The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen
    • Hockings J.K., Thorne P.A., Kemp M.Q., Morgan S.S., Selmin O., and Romagnolo D.F. The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen. Cancer Res 66 (2006) 2224-2232
    • (2006) Cancer Res , vol.66 , pp. 2224-2232
    • Hockings, J.K.1    Thorne, P.A.2    Kemp, M.Q.3    Morgan, S.S.4    Selmin, O.5    Romagnolo, D.F.6


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