메뉴 건너뛰기




Volumn 135, Issue 1, 2013, Pages 81-90

Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway

Author keywords

CTLA 4; GVHD; IDO; T regulatory cell; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; N METHYLTRYPTOPHAN;

EID: 84883203665     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft140     Document Type: Article
Times cited : (11)

References (43)
  • 3
    • 77953719954 scopus 로고    scopus 로고
    • Functional and phenotypic effects of AhR activation in inflammatory dendritic cells
    • Bankoti, J., Rase, B., Simones, T., and Shepherd, D. M. (2010). Functional and phenotypic effects of AhR activation in inflammatory dendritic cells. Toxicol. Appl. Pharmacol. 246, 18-28.
    • (2010) Toxicol. Appl. Pharmacol. , vol.246 , pp. 18-28
    • Bankoti, J.1    Rase, B.2    Simones, T.3    Shepherd, D.M.4
  • 4
    • 78650307650 scopus 로고    scopus 로고
    • Involvement of IFN-γ and perforin, but not Fas/FasL interactions in regulatory T cell-mediated suppression of experimental autoimmune encephalomyelitis
    • Beeston, T., Smith, T. R. F., Maricic, I., Tang, X., and Kumar, V. (2010). Involvement of IFN-γ and perforin, but not Fas/FasL interactions in regulatory T cell-mediated suppression of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 229, 91-97.
    • (2010) J. Neuroimmunol. , vol.229 , pp. 91-97
    • Beeston, T.1    Smith, T.R.F.2    Maricic, I.3    Tang, X.4    Kumar, V.5
  • 5
    • 79952096263 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor activation by TCDD reduces inflammation associated with Crohn's disease
    • Benson, J. M., and Shepherd, D. M. (2011). Aryl hydrocarbon receptor activation by TCDD reduces inflammation associated with Crohn's disease. Toxicol. Sci. 120, 68-78.
    • (2011) Toxicol. Sci. , vol.120 , pp. 68-78
    • Benson, J.M.1    Shepherd, D.M.2
  • 6
    • 0032528482 scopus 로고    scopus 로고
    • Murine graft-versus-host disease in an F1-hybrid model using IFN-gamma gene knockout donors
    • Ellison, C. A., Fischer, J. M. M., HayGlass, K. T., and Gartner, J. G. (1998). Murine graft-versus-host disease in an F1-hybrid model using IFN-gamma gene knockout donors. J. Immunol. 161, 631-640.
    • (1998) J. Immunol. , vol.161 , pp. 631-640
    • Ellison, C.A.1    Fischer, J.M.M.2    HayGlass, K.T.3    Gartner, J.G.4
  • 7
    • 25444526629 scopus 로고    scopus 로고
    • Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells
    • Funatake, C. J., Marshall, N. B., Steppan, L. B., Mourich, D. V., and Kerkvliet, N. I. (2005). Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells. J. Immunol. 175, 4184-4188.
    • (2005) J. Immunol. , vol.175 , pp. 4184-4188
    • Funatake, C.J.1    Marshall, N.B.2    Steppan, L.B.3    Mourich, D.V.4    Kerkvliet, N.I.5
  • 8
    • 77955859470 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells
    • Gandhi, R., Kumar, D., Burns, E. J., Nadeau, M., Dake, B., Laroni, A., Kozoriz, D., Weiner, H. L., and Quintana, F. J. (2010). Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Nat. Immunol. 11, 846-853.
    • (2010) Nat. Immunol. , vol.11 , pp. 846-853
    • Gandhi, R.1    Kumar, D.2    Burns, E.J.3    Nadeau, M.4    Dake, B.5    Laroni, A.6    Kozoriz, D.7    Weiner, H.L.8    Quintana, F.J.9
  • 11
    • 0034176031 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
    • Hwu, P., Du, M. X., Lapointe, R., Do, M., Taylor, M. W., and Young, H. A. (2000). Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation. J. Immunol. 164, 3596-3599.
    • (2000) J. Immunol. , vol.164 , pp. 3596-3599
    • Hwu, P.1    Du, M.X.2    Lapointe, R.3    Do, M.4    Taylor, M.W.5    Young, H.A.6
  • 13
    • 0036944759 scopus 로고    scopus 로고
    • T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD
    • Kerkvliet, N. I., Shepherd, D. M., and Baecher-Steppan, L. (2002). T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD. Toxicol. Appl. Pharmacol. 185, 146-152.
    • (2002) Toxicol. Appl. Pharmacol. , vol.185 , pp. 146-152
    • Kerkvliet, N.I.1    Shepherd, D.M.2    Baecher-Steppan, L.3
  • 14
    • 74549198640 scopus 로고    scopus 로고
    • Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3+ T cells in pancreatic lymph nodes
    • Kerkvliet, N. I., Steppan, L. B., Vorachek, W., Oda, S., Farrer, D., Wong, C. P. Pham, D. and Mourich, D. V. (2009). Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3+ T cells in pancreatic lymph nodes. Immunotherapy 1, 539-547.
    • (2009) Immunotherapy , vol.1 , pp. 539-547
    • Kerkvliet, N.I.1    Steppan, L.B.2    Vorachek, W.3    Oda, S.4    Farrer, D.5    Wong, C.P.6    Pham, D.7    Mourich, D.V.8
  • 16
    • 23444449846 scopus 로고    scopus 로고
    • Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation
    • Kwidzinski, E., Bunse, J., Aktas, O., Richter, D., Mutlu, L., Zipp, F., Nitsch, R., and Bechmann, I. (2005). Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation. FASEB J. 19, 1347-1349.
    • (2005) FASEB J. , vol.19 , pp. 1347-1349
    • Kwidzinski, E.1    Bunse, J.2    Aktas, O.3    Richter, D.4    Mutlu, L.5    Zipp, F.6    Nitsch, R.7    Bechmann, I.8
  • 17
    • 2642655282 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
    • Luhder, F., Höglund, P., Allison, J. P., Benoist, C., and Mathis, D. (1998). Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J. Exp. Med. 187, 427-432.
    • (1998) J. Exp. Med. , vol.187 , pp. 427-432
    • Luhder, F.1    Höglund, P.2    Allison, J.P.3    Benoist, C.4    Mathis, D.5
  • 18
    • 0032103285 scopus 로고    scopus 로고
    • Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4
    • Markees, T. G., Phillips, N. E., Gordon, E. J., Noelle, R. J., Shultz, L. D., Mordes, J. P., Greiner, D. L., and Rossini, A. A. (1998). Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J. Clin. Invest. 101, 2446-2455.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2446-2455
    • Markees, T.G.1    Phillips, N.E.2    Gordon, E.J.3    Noelle, R.J.4    Shultz, L.D.5    Mordes, J.P.6    Greiner, D.L.7    Rossini, A.A.8
  • 19
    • 75749087979 scopus 로고    scopus 로고
    • Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells
    • Marshall, N. B., and Kerkvliet, N. I. (2010). Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells. Ann. N. Y. Acad. Sci. 1183, 25-37.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1183 , pp. 25-37
    • Marshall, N.B.1    Kerkvliet, N.I.2
  • 20
    • 53149148154 scopus 로고    scopus 로고
    • Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo- p-dioxin
    • Marshall, N. B., Vorachek, W. R., Steppan, L. B., Mourich, D. V., and Kerkvliet, N. I. (2008). Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo- p-dioxin. J. Immunol. 181, 2382-2391.
    • (2008) J. Immunol. , vol.181 , pp. 2382-2391
    • Marshall, N.B.1    Vorachek, W.R.2    Steppan, L.B.3    Mourich, D.V.4    Kerkvliet, N.I.5
  • 22
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: tolerance and tryptophan catabolism
    • Mellor, A. L., and Munn, D. H. (2004). IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat. Rev. Immunol. 4, 762-774.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 23
    • 78649880396 scopus 로고    scopus 로고
    • An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
    • Mezrich, J. D., Fechner, J. H., Zhang, X., Johnson, B. P., Burlingham, W. J., and Bradfield, C. A. (2010). An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. J. Immunol. 185, 3190-3198.
    • (2010) J. Immunol. , vol.185 , pp. 3190-3198
    • Mezrich, J.D.1    Fechner, J.H.2    Zhang, X.3    Johnson, B.P.4    Burlingham, W.J.5    Bradfield, C.A.6
  • 24
    • 1642396607 scopus 로고    scopus 로고
    • Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
    • Munn, D. H., Sharma, M. D., and Mellor, A. L. (2004). Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol. 172, 4100-4110.
    • (2004) J. Immunol. , vol.172 , pp. 4100-4110
    • Munn, D.H.1    Sharma, M.D.2    Mellor, A.L.3
  • 27
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
    • Peggs, K. S., Quezada, S. A., Chambers, C. A., Korman, A. J., and Allison, J. P. (2009). Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 206, 1717-1725.
    • (2009) J. Exp. Med. , vol.206 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 28
    • 0030586626 scopus 로고    scopus 로고
    • CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis
    • Perrin, P., Maldonado, J., Davis, T., June, C., and Racke, M. (1996). CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis. J. Immunol. 157, 1333-1336.
    • (1996) J. Immunol. , vol.157 , pp. 1333-1336
    • Perrin, P.1    Maldonado, J.2    Davis, T.3    June, C.4    Racke, M.5
  • 29
    • 3142734334 scopus 로고    scopus 로고
    • Differential requirement for IFN-gamma in CTL maturation in acute murine graft-versus- host disease
    • Puliaev, R., Nguyen, P., Finkelman, F. D., and Via, C. S. (2004). Differential requirement for IFN-gamma in CTL maturation in acute murine graft-versus- host disease. J. Immunol. 173, 910-919.
    • (2004) J. Immunol. , vol.173 , pp. 910-919
    • Puliaev, R.1    Nguyen, P.2    Finkelman, F.D.3    Via, C.S.4
  • 31
    • 0036341332 scopus 로고    scopus 로고
    • Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis
    • Sakurai, K., Zou, J. P., Tschetter, J. R., Ward, J. M., and Shearer, G. M. (2002). Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 129, 186-196.
    • (2002) J. Neuroimmunol. , vol.129 , pp. 186-196
    • Sakurai, K.1    Zou, J.P.2    Tschetter, J.R.3    Ward, J.M.4    Shearer, G.M.5
  • 32
    • 22344434572 scopus 로고    scopus 로고
    • IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
    • Sawitzki, B., Kingsley, C. I., Oliveira, V., Karim, M., Herber, M., and Wood, K. J. (2005). IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo. J. Exp. Med. 201, 1925-1935.
    • (2005) J. Exp. Med. , vol.201 , pp. 1925-1935
    • Sawitzki, B.1    Kingsley, C.I.2    Oliveira, V.3    Karim, M.4    Herber, M.5    Wood, K.J.6
  • 33
    • 38449111402 scopus 로고    scopus 로고
    • The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
    • Saxena, V., Ondr, J. K., Magnusen, A. F., Munn, D. H., and Katz, J. D. (2007). The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J. Immunol. 179, 5041-5053.
    • (2007) J. Immunol. , vol.179 , pp. 5041-5053
    • Saxena, V.1    Ondr, J.K.2    Magnusen, A.F.3    Munn, D.H.4    Katz, J.D.5
  • 34
    • 0033613173 scopus 로고    scopus 로고
    • In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance
    • Sotomayor, E. M., Borrello, I., Tubb, E., Allison, J. P., and Levitsky, H. I. (1999). In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance. Proc. Natl. Acad. Sci. U.S.A. 96, 11476-11481.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 11476-11481
    • Sotomayor, E.M.1    Borrello, I.2    Tubb, E.3    Allison, J.P.4    Levitsky, H.I.5
  • 35
  • 36
    • 50949098849 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase
    • Vogel, C. F. A., Goth, S. R., Dong, B., Pessah, I. N., and Matsumura, F. (2008). Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem. Biophys. Res. Commun. 375, 331-335.
    • (2008) Biochem. Biophys. Res. Commun. , vol.375 , pp. 331-335
    • Vogel, C.F.A.1    Goth, S.R.2    Dong, B.3    Pessah, I.N.4    Matsumura, F.5
  • 37
    • 34848920850 scopus 로고    scopus 로고
    • Involvement of RelB in aryl hydrocarbon receptor-mediated induction of chemokines
    • Vogel, C. F. A., Sciullo, E., and Matsumura, F. (2007). Involvement of RelB in aryl hydrocarbon receptor-mediated induction of chemokines. Biochem. Biophys. Res. Commun. 363, 722-726.
    • (2007) Biochem. Biophys. Res. Commun. , vol.363 , pp. 722-726
    • Vogel, C.F.A.1    Sciullo, E.2    Matsumura, F.3
  • 40
    • 57349143302 scopus 로고    scopus 로고
    • Cytotoxic- T-lymphocyte-associated antigen 4 blockade abrogates protection by regulatory T cells in a mouse model of microbially induced innate immune-driven colitis
    • Watanabe, K., Rao, V. P., Poutahidis, T., Rickman, B. H., Ohtani, M., Xu, S., Rogers, A. B., Ge, Z., Horwitz, B. H., Fujioka, T., et al. (2008). Cytotoxic- T-lymphocyte-associated antigen 4 blockade abrogates protection by regulatory T cells in a mouse model of microbially induced innate immune-driven colitis. Infect. Immun. 76, 5834-5842.
    • (2008) Infect. Immun. , vol.76 , pp. 5834-5842
    • Watanabe, K.1    Rao, V.P.2    Poutahidis, T.3    Rickman, B.H.4    Ohtani, M.5    Xu, S.6    Rogers, A.B.7    Ge, Z.8    Horwitz, B.H.9    Fujioka, T.10
  • 41
    • 72549089070 scopus 로고    scopus 로고
    • IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells
    • Wei, B., Baker, S., Wieckiewicz, J., and Wood, K. J. (2010). IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells. Am. J. Transplant. 10, 69-80.
    • (2010) Am. J. Transplant. , vol.10 , pp. 69-80
    • Wei, B.1    Baker, S.2    Wieckiewicz, J.3    Wood, K.J.4
  • 42
    • 0032535087 scopus 로고    scopus 로고
    • Donor-derived interferon gamma is required for inhibition of acute graftversus- host disease by interleukin 12
    • Yang, Y. G., Dey, B. R., Sergio, J. J., Pearson, D. A., and Sykes, M. (1998). Donor-derived interferon gamma is required for inhibition of acute graftversus- host disease by interleukin 12. J. Clin. Invest. 102, 2126-2135.
    • (1998) J. Clin. Invest. , vol.102 , pp. 2126-2135
    • Yang, Y.G.1    Dey, B.R.2    Sergio, J.J.3    Pearson, D.A.4    Sykes, M.5
  • 43
    • 77951242329 scopus 로고    scopus 로고
    • Suppression of experimental autoimmune uveoretinitis by inducing differentiation of regulatory T cells via activation of aryl hydrocarbon receptor
    • Zhang, L., Ma, J., Takeuchi, M., Usui, Y., Hattori, T., Okunuki, Y., Yamakawa, N., Kezuka, T., Kuroda, M., and Goto, H. (2010). Suppression of experimental autoimmune uveoretinitis by inducing differentiation of regulatory T cells via activation of aryl hydrocarbon receptor. Invest. Ophthalmol. Vis. Sci. 51, 2109-2117.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 2109-2117
    • Zhang, L.1    Ma, J.2    Takeuchi, M.3    Usui, Y.4    Hattori, T.5    Okunuki, Y.6    Yamakawa, N.7    Kezuka, T.8    Kuroda, M.9    Goto, H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.