-
1
-
-
0000049842
-
The remaking of chromosomes
-
Muller H: The remaking of chromosomes. Collecting Net 1938;13:181-198.
-
(1938)
Collecting Net
, vol.13
, pp. 181-198
-
-
Muller, H.1
-
4
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith JD, Comeau L, Rosenfield S, Stansel RM, Bianchi A, et al: Mammalian telomeres end in a large duplex loop. Cell 1999;97:503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
Stansel, R.M.4
Bianchi, A.5
-
5
-
-
79954474478
-
Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance
-
Oganesian L, Karlseder J: Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance. Mol Cell 2011; 42:224-236.
-
(2011)
Mol Cell
, vol.42
, pp. 224-236
-
-
Oganesian, L.1
Karlseder, J.2
-
6
-
-
7644237444
-
Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops
-
Cesare AJ, Griffith JD: Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops. Mol Cell Biol 2004;24:9948-9957.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9948-9957
-
-
Cesare, A.J.1
Griffith, J.D.2
-
7
-
-
81255209208
-
Normal mammalian cells negatively regulate telomere length by telomere trimming
-
Pickett HA, Henson JD, Au AY, Neumann AA, Reddel RR: Normal mammalian cells negatively regulate telomere length by telomere trimming. Hum Mol Genet 2011;20:4684-4692.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 4684-4692
-
-
Pickett, H.A.1
Henson, J.D.2
Au, A.Y.3
Neumann, A.A.4
Reddel, R.R.5
-
8
-
-
0030590069
-
Telomere reduction and telomerase inactivation during neuronal cell differentiation
-
Kruk PA, Balajee AS, Rao KS, Bohr VA: Telomere reduction and telomerase inactivation during neuronal cell differentiation. Biochem Biophys Res Commun 1996;224:487-492.
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 487-492
-
-
Kruk, P.A.1
Balajee, A.S.2
Rao, K.S.3
Bohr, V.A.4
-
9
-
-
33144456602
-
Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans
-
Britt-Compton B, Rowson J, Locke M, Mackenzie I, Kipling D, Baird DM: Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans. Hum Mol Genet 2006;15:725-733.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 725-733
-
-
Britt-Compton, B.1
Rowson, J.2
Locke, M.3
MacKenzie, I.4
Kipling, D.5
Baird, D.M.6
-
11
-
-
39749134753
-
A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
-
Chen Y, Yang Y van Overbeek M, Donigian JR, Baciu P, et al: A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science 2008;319:1092-1096.
-
(2008)
Science
, vol.319
, pp. 1092-1096
-
-
Chen, Y.1
Yang, Y.2
Can Overbeek, M.3
Donigian, J.R.4
Baciu, P.5
-
12
-
-
22144490491
-
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
-
Celli GB, de Lange T: DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat Cell Biol 2005; 7:712-718.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 712-718
-
-
Celli, G.B.1
De Lange, T.2
-
13
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
van Steensel B, de Lange T: Control of telomere length by the human telomeric protein TRF1. Nature 1997;385:740-743.
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
Van Steensel, B.1
De Lange, T.2
-
14
-
-
0033961281
-
Control of human telomere length by TRF1 and TRF2
-
Smogorzewska A, van Steensel B, Bianchi A, Oelmann S, Schaefer MR, et al: Control of human telomere length by TRF1 and TRF2. Mol Cell Biol 2000;20:1659-1668.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1659-1668
-
-
Smogorzewska, A.1
Van Steensel, B.2
Bianchi, A.3
Oelmann, S.4
Schaefer, M.R.5
-
15
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusions
-
van Steensel B, Smogorzewska A, de Lange T: TRF2 protects human telomeres from end-to-end fusions. Cell 1998;92:401-413.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
Van Steensel, B.1
Smogorzewska, A.2
De Lange, T.3
-
16
-
-
67649635974
-
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
-
Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, et al: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 2009;138:90-103.
-
(2009)
Cell
, vol.138
, pp. 90-103
-
-
Sfeir, A.1
Kosiyatrakul, S.T.2
Hockemeyer, D.3
MacRae, S.L.4
Karlseder, J.5
-
17
-
-
77954958609
-
TRF2 and Apollo Cooperate with Topoi-somerase 2alpha to Protect Human Telomeres from Replicative Damage
-
Ye J, Lenain C, Bauwens S, Rizzo A, Saint-Leger A, et al: TRF2 and Apollo cooperate with topoi-somerase 2alpha to protect human telomeres from replicative damage. Cell 2010;142:230-242.
-
(2010)
Cell
, vol.142
, pp. 230-242
-
-
Ye, J.1
Lenain, C.2
Bauwens, S.3
Rizzo, A.4
Saint-Leger, A.5
-
18
-
-
77954958459
-
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
-
Lam YC, Akhter S, Gu P, Ye J, Poulet A, et al: SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. EMBO J 2010;29:2230-2241.
-
(2010)
EMBO J
, vol.29
, pp. 2230-2241
-
-
Lam, Y.C.1
Akhter, S.2
Gu, P.3
Ye, J.4
Poulet, A.5
-
19
-
-
0038451396
-
POT1 as a terminal transducer of TRF1 telomere length control
-
Loayza D, De Lange T: POT1 as a terminal transducer of TRF1 telomere length control. Nature 2003; 423:1013-1018.
-
(2003)
Nature
, vol.423
, pp. 1013-1018
-
-
Loayza, D.1
De Lange, T.2
-
21
-
-
33745685066
-
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
-
Hockemeyer D, Daniels J P, Takai H, de Lange T: Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 2006;126:63-77.
-
(2006)
Cell
, vol.126
, pp. 63-77
-
-
Hockemeyer, D.1
Daniels, J.P.2
Takai, H.3
De Lange, T.4
-
22
-
-
33745713451
-
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
-
Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, et al: Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell 2006;126:49-62.
-
(2006)
Cell
, vol.126
, pp. 49-62
-
-
Wu, L.1
Multani, A.S.2
He, H.3
Cosme-Blanco, W.4
Deng, Y.5
-
23
-
-
75749092997
-
Telomere protection by TPP1 is mediated by POT1a and POT1b
-
Kibe T, Osawa GA, Keegan CE, de Lange T: Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol Cell Biol 2010;30:1059-1066.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 1059-1066
-
-
Kibe, T.1
Osawa, G.A.2
Keegan, C.E.3
De Lange, T.4
-
24
-
-
33750446640
-
POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination
-
He H, Multani AS, Cosme-Blanco W, Tahara H, Ma J, et al: POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination. EMBO J 2006;25:5180-5190.
-
(2006)
EMBO J
, vol.25
, pp. 5180-5190
-
-
He, H.1
Multani, A.S.2
Cosme-Blanco, W.3
Tahara, H.4
Ma, J.5
-
25
-
-
82955207699
-
Essential roles for Pot1b in hematopoietic stem cell self-renewal and survival
-
Wang Y, Shen MF, Chang S: Essential roles for Pot1b in hematopoietic stem cell self-renewal and survival. Blood 2011;118:6068-6077.
-
(2011)
Blood
, vol.118
, pp. 6068-6077
-
-
Wang, Y.1
Shen, M.F.2
Chang, S.3
-
26
-
-
72849126603
-
Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN
-
Arnoult N, Saintome C, Ourliac-Garnier I, Riou JF, Londono-Vallejo A: Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN. Genes Dev 2009;23:2915-2924.
-
(2009)
Genes Dev
, vol.23
, pp. 2915-2924
-
-
Arnoult, N.1
Saintome, C.2
Ourliac-Garnier, I.3
Riou, J.F.4
Londono-Vallejo, A.5
-
27
-
-
70349270554
-
Caudal regression in adre-nocortical dysplasia (acd) mice is caused by telom-ere dysfunction with subsequent p53-dependent apoptosis
-
Vlangos CN, O'Connor BC, Morley MJ, Krause AS, Osawa GA, Keegan CE: Caudal regression in adre-nocortical dysplasia (acd) mice is caused by telom-ere dysfunction with subsequent p53-dependent apoptosis. Dev Biol 2009;334:418-428.
-
(2009)
Dev Biol
, vol.334
, pp. 418-428
-
-
Vlangos, C.N.1
O'Connor, B.C.2
Morley, M.J.3
Krause, A.S.4
Osawa, G.A.5
Keegan, C.E.6
-
28
-
-
34547670213
-
Telomere protection by mammalian Pot1 requires interaction with Tpp1
-
Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, et al: Telomere protection by mammalian Pot1 requires interaction with Tpp1. Nat Struct Mol Biol 2007;14:754-761.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 754-761
-
-
Hockemeyer, D.1
Palm, W.2
Else, T.3
Daniels, J.P.4
Takai, K.K.5
-
29
-
-
33846691378
-
The POT1-TPP1 telomere complex is a telomerase processivity factor
-
Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, et al: The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 2007;445:506-510.
-
(2007)
Nature
, vol.445
, pp. 506-510
-
-
Wang, F.1
Podell, E.R.2
Zaug, A.J.3
Yang, Y.4
Baciu, P.5
-
30
-
-
77952898835
-
TPP1 is required for TERT recruitment telomere elongation during nuclear reprogramming and normal skin development in Mice
-
Tejera AM, Stagno d'Alcontres M, Thanasoula M, Marion RM, Martinez P, et al: TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Dev Cell 2010;18:775-789.
-
(2010)
Dev Cell
, vol.18
, pp. 775-789
-
-
Tejera, A.M.1
Stagno D'Alcontres, M.2
Thanasoula, M.3
Marion, R.M.4
Martinez, P.5
-
31
-
-
77958460546
-
Taking apart Rap1: An adaptor protein with telomeric and non-telomeric functions
-
Kabir S, Sfeir A, de Lange T: Taking apart Rap1: an adaptor protein with telomeric and non-telomeric functions. Cell Cycle 2010;9:4061-4067.
-
(2010)
Cell Cycle
, vol.9
, pp. 4061-4067
-
-
Kabir, S.1
Sfeir, A.2
De Lange, T.3
-
32
-
-
77950196212
-
Loss of Rap1 induces telomere recombination in the absence of NHEJ or A DNA damage signal
-
Sfeir A, Kabir S, van Overbeek M, Celli GB, de Lange T: Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal. Science 2010;327:1657-1661.
-
(2010)
Science
, vol.327
, pp. 1657-1661
-
-
Sfeir, A.1
Kabir, S.2
Van Overbeek, M.3
Celli, G.B.4
De Lange, T.5
-
33
-
-
3142616449
-
The human Rap1 protein complex and modulation of telomere length
-
O'Connor MS, Safari A, Liu D, Qin J, Songyang Z: The human Rap1 protein complex and modulation of telomere length. J Biol Chem 2004;279:28585-28591.
-
(2004)
J Biol Chem
, vol.279
, pp. 28585-28591
-
-
O'Connor, M.S.1
Safari, A.2
Liu, D.3
Qin, J.4
Songyang, Z.5
-
34
-
-
79960112520
-
Human telomeric proteins occupy selective interstitial sites
-
Yang D, Xiong Y, Kim H, He Q, Li Y, et al: Human telomeric proteins occupy selective interstitial sites. Cell Res 2011;21:1013-1027.
-
(2011)
Cell Res
, vol.21
, pp. 1013-1027
-
-
Yang, D.1
Xiong, Y.2
Kim, H.3
He, Q.4
Li, Y.5
-
35
-
-
6344289975
-
TIN2 mediates functions of TRF2 at human telomeres
-
Kim SH, Beausejour C, Davalos AR, Kaminker P, Heo SJ, Campisi J: TIN2 mediates functions of TRF2 at human telomeres. J Biol Chem 2004;279:43799-43804.
-
(2004)
J Biol Chem
, vol.279
, pp. 43799-43804
-
-
Kim, S.H.1
Beausejour, C.2
Davalos, A.R.3
Kaminker, P.4
Heo, S.J.5
Campisi, J.6
-
36
-
-
0032553473
-
Tankyrase, a poly(ADP-ribose) polymerase at human telom-eres
-
Smith S, Giriat I, Schmitt A, de Lange T: Tankyrase, a poly(ADP-ribose) polymerase at human telom-eres. Science 1998;282:1484-1487.
-
(1998)
Science
, vol.282
, pp. 1484-1487
-
-
Smith, S.1
Giriat, I.2
Schmitt, A.3
De Lange, T.4
-
37
-
-
80052468708
-
A role for heterochromatin protein 1gamma at human telomeres
-
Canudas S, Houghtaling BR, Bhanot M, Sasa G, Savage SA, et al: A role for heterochromatin protein 1gamma at human telomeres. Genes Dev 2011;25:1807-1819.
-
(2011)
Genes Dev
, vol.25
, pp. 1807-1819
-
-
Canudas, S.1
Houghtaling, B.R.2
Bhanot, M.3
Sasa, G.4
Savage, S.A.5
-
38
-
-
3242709415
-
Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway
-
Chiang YJ, Kim SH, Tessarollo L, Campisi J, Hodes RJ: Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway. Mol Cell Biol 2004;24:6631-6634.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6631-6634
-
-
Chiang, Y.J.1
Kim, S.H.2
Tessarollo, L.3
Campisi, J.4
Hodes, R.J.5
-
39
-
-
33745226438
-
The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure
-
Galati A, Rossetti L, Pisano S, Chapman L, Rhodes D, et al: The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure. J Mol Biol 2006;360:377-385.
-
(2006)
J Mol Biol
, vol.360
, pp. 377-385
-
-
Galati, A.1
Rossetti, L.2
Pisano, S.3
Chapman, L.4
Rhodes, D.5
-
40
-
-
40949100837
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltrans-ferases
-
Benetti R, Gonzalo S, Jaco I, Munoz P, Gonzalez S, et al: A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltrans-ferases. Nat Struct Mol Biol 2008;15:268-279.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 268-279
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Munoz, P.4
Gonzalez, S.5
-
41
-
-
51349167747
-
No overt nucleosome eviction at deprotected telomeres
-
Wu P, de Lange T: No overt nucleosome eviction at deprotected telomeres. Mol Cell Biol 2008;28:5724-5735.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5724-5735
-
-
Wu, P.1
De Lange, T.2
-
42
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti R, Garcia-Cao M, Blasco MA: Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 2007;39:243-250.
-
(2007)
Nat Genet
, vol.39
, pp. 243-250
-
-
Benetti, R.1
Garcia-Cao, M.2
Blasco, M.A.3
-
43
-
-
77049094890
-
Chromatin regulation and Non-coding RNAs at Mammalian telomeres
-
Schoeftner S, Blasco MA: Chromatin regulation and non-coding RNAs at mammalian telomeres. Semin Cell Dev Biol 2010;21:186-193.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 186-193
-
-
Schoeftner, S.1
Blasco, M.A.2
-
44
-
-
25144491542
-
Role of Rb family in the epi-genetic definition of chromatin
-
Gonzalo S, Blasco MA: Role of Rb family in the epi-genetic definition of chromatin. Cell Cycle 2005;4:752-755.
-
(2005)
Cell Cycle
, vol.4
, pp. 752-755
-
-
Gonzalo, S.1
Blasco, M.A.2
-
45
-
-
29244467484
-
Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length
-
Woodcock CL, Skoultchi AI, Fan Y: Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length. Chromosome Res 2006;14:17-25.
-
(2006)
Chromosome Res
, vol.14
, pp. 17-25
-
-
Woodcock, C.L.1
Skoultchi, A.I.2
Fan, Y.3
-
46
-
-
29244449333
-
Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation
-
Fan Y, Nikitina T, Zhao J, Fleury TJ, Bhattacharyya R, et al: Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell 2005;123:1199-1212.
-
(2005)
Cell
, vol.123
, pp. 1199-1212
-
-
Fan, Y.1
Nikitina, T.2
Zhao, J.3
Fleury, T.J.4
Bhattacharyya, R.5
-
47
-
-
34748902384
-
Global chromatin compaction limits the strength of the DNA damage response
-
Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, et al: Global chromatin compaction limits the strength of the DNA damage response. J Cell Biol 2007;178:1101-1108.
-
(2007)
J Cell Biol
, vol.178
, pp. 1101-1108
-
-
Murga, M.1
Jaco, I.2
Fan, Y.3
Soria, R.4
Martinez-Pastor, B.5
-
48
-
-
0037148368
-
Transcriptional silencing at Saccharomyces telomeres: Implications for other organisms
-
Tham WH, Zakian VA: Transcriptional silencing at Saccharomyces telomeres: implications for other organisms. Oncogene 2002;21:512-521.
-
(2002)
Oncogene
, vol.21
, pp. 512-521
-
-
Tham, W.H.1
Zakian, V.A.2
-
49
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromo some ends
-
Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J: Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromo some ends. Science 2007;318:798-801.
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
Reichenbach, P.2
Khoriauli, L.3
Giulotto, E.4
Lingner, J.5
-
50
-
-
73249117060
-
CpG-Island promoters drive transcription of human telomeres
-
Nergadze SG, Farnung BO, Wischnewski H, Khoriauli L, Vitelli V, et al: CpG-Island promoters drive transcription of human telomeres. RNA 2009;15:2186-2194.
-
(2009)
RNA
, vol.15
, pp. 2186-2194
-
-
Nergadze, S.G.1
Farnung, B.O.2
Wischnewski, H.3
Khoriauli, L.4
Vitelli, V.5
-
51
-
-
38849111756
-
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
-
Schoeftner S, Blasco MA: Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat Cell Biol 2008;10:228-236.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 228-236
-
-
Schoeftner, S.1
Blasco, M.A.2
-
52
-
-
77957243987
-
The Non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
-
Redon S, Reichenbach P, Lingner J: The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res 2010;38:5797-5806.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5797-5806
-
-
Redon, S.1
Reichenbach, P.2
Lingner, J.3
-
53
-
-
68149110347
-
Ku86 represses lethal telomere deletion events in human somatic cells
-
Wang Y, Ghosh G, Hendrickson EA: Ku86 represses lethal telomere deletion events in human somatic cells. Proc Natl Acad Sci USA 2009;106:12430-12435.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12430-12435
-
-
Wang, Y.1
Ghosh, G.2
Hendrickson, E.A.3
-
54
-
-
3342972121
-
Does a sentinel or a subset of short telomeres determine replicative senescence?
-
Zou Y, Sfeir A, Gryaznov SM, Shay J W, Wright WE: Does a sentinel or a subset of short telomeres determine replicative senescence? Mol Biol Cell 2004; 15:3709-3718.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3709-3718
-
-
Zou, Y.1
Sfeir, A.2
Gryaznov, S.M.3
Shay, J.W.4
Wright, W.E.5
-
55
-
-
67651151301
-
Radiation sensitivity increases with proliferation-associated telomere dysfunction in nontransformed human epithelial cells
-
Soler D, Pampalona J, Tusell L, Genesca A: Radiation sensitivity increases with proliferation-associated telomere dysfunction in nontransformed human epithelial cells. Aging Cell 2009;8:414-425.
-
(2009)
Aging Cell
, vol.8
, pp. 414-425
-
-
Soler, D.1
Pampalona, J.2
Tusell, L.3
Genesca, A.4
-
57
-
-
0034003333
-
A critical role for telom-eres in suppressing and facilitating carcinogenesis
-
Artandi SE, DePinho RA: A critical role for telom-eres in suppressing and facilitating carcinogenesis. Curr Opin Genet Dev 2000;10:39-46.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 39-46
-
-
Artandi, S.E.1
Depinho, R.A.2
-
58
-
-
77954374058
-
Telomere length and risk of incident cancer and cancer mortality
-
Willeit P, Willeit J, Mayr A, Weger S, Oberhollenzer F, et al: Telomere length and risk of incident cancer and cancer mortality. JAMA 2010;304:69-75.
-
(2010)
JAMA
, vol.304
, pp. 69-75
-
-
Willeit, P.1
Willeit, J.2
Mayr, A.3
Weger, S.4
Oberhollenzer, F.5
-
59
-
-
79952017845
-
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
-
Martinez P, Blasco MA: Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nat Rev Cancer 2011;11:161-176.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 161-176
-
-
Martinez, P.1
Blasco, M.A.2
-
60
-
-
0038025489
-
Telomere repeat binding factors: Keeping the ends in check
-
Karlseder J: Telomere repeat binding factors: keeping the ends in check. Cancer Lett 2003;194:189-197.
-
(2003)
Cancer Lett
, vol.194
, pp. 189-197
-
-
Karlseder, J.1
-
61
-
-
69749092744
-
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
-
Martinez P, Thanasoula M, Munoz P, Liao C, Tejera A, et al: Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev 2009;23:2060-2075.
-
(2009)
Genes Dev
, vol.23
, pp. 2060-2075
-
-
Martinez, P.1
Thanasoula, M.2
Munoz, P.3
Liao, C.4
Tejera, A.5
-
62
-
-
62849084852
-
TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis
-
Munoz P, Blanco R, de Carcer G, Schoeftner S, Benetti R, et al: TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis. Mol Cell Biol 2009;29:1608-1625.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1608-1625
-
-
Munoz, P.1
Blanco, R.2
De Carcer, G.3
Schoeftner, S.4
Benetti, R.5
-
63
-
-
27144515686
-
XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
-
Munoz P, Blanco R, Flores JM, Blasco MA: XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nat Genet 2005;37:1063-1071.
-
(2005)
Nat Genet
, vol.37
, pp. 1063-1071
-
-
Munoz, P.1
Blanco, R.2
Flores, J.M.3
Blasco, M.A.4
-
64
-
-
33645534488
-
The role of telomeres and telomerase in the pathology of human cancer and aging
-
Shin JS, Hong A, Solomon MJ, Lee CS: The role of telomeres and telomerase in the pathology of human cancer and aging. Pathology 2006;38:103-113.
-
(2006)
Pathology
, vol.38
, pp. 103-113
-
-
Shin, J.S.1
Hong, A.2
Solomon, M.J.3
Lee, C.S.4
-
67
-
-
0033199695
-
Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
-
Yeager TR, Neumann AA, Englezou A, Huschtscha LI, Noble JR, Reddel RR: Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 1999;59:4175-4179.
-
(1999)
Cancer Res
, vol.59
, pp. 4175-4179
-
-
Yeager, T.R.1
Neumann, A.A.2
Englezou, A.3
Huschtscha, L.I.4
Noble, J.R.5
Reddel, R.R.6
-
68
-
-
71849088980
-
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telo-meres activity
-
Henson JD, Cao Y, Huschtscha LI, Chang AC, Au AY, et al: DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telo-meres activity. Nat Biotechnol 2009;27:1181-1185.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 1181-1185
-
-
Henson, J.D.1
Cao, Y.2
Huschtscha, L.I.3
Chang, A.C.4
Au, A.Y.5
-
69
-
-
59249090880
-
Unusual telomeric DNAs in human telomerase-negative immortalized cells
-
Nabetani A, Ishikawa F: Unusual telomeric DNAs in human telomerase-negative immortalized cells. Mol Cell Biol 2009;29:703-713.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 703-713
-
-
Nabetani, A.1
Ishikawa, F.2
-
70
-
-
1942538563
-
Alternative lengthening of telomeres is characterized by high rates of inter-telomeric exchange
-
Londoño-Vallejo JA, Der-Sarkissian H, Cazes L, Bacchetti S, Reddel R: Alternative lengthening of telomeres is characterized by high rates of inter-telomeric exchange. Cancer Res 2004;64:2324-2327.
-
(2004)
Cancer Res
, vol.64
, pp. 2324-2327
-
-
Londoño-Vallejo, J.A.1
Der-Sarkissian, H.2
Cazes, L.3
Bacchetti, S.4
Reddel, R.5
-
71
-
-
4644336189
-
The frequency of homologous recombination in human ALT cells
-
Bechter OE, Shay J W, Wright WE: The frequency of homologous recombination in human ALT cells. Cell Cycle 2004;3:547-549.
-
(2004)
Cell Cycle
, vol.3
, pp. 547-549
-
-
Bechter, O.E.1
Shay, J.W.2
Wright, W.E.3
-
72
-
-
77951133257
-
Alternative lengthening of telomeres: Models mechanisms and implications
-
Cesare AJ, Reddel RR: Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 2010;11:319-330.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 319-330
-
-
Cesare, A.J.1
Reddel, R.R.2
-
73
-
-
36749034760
-
Telomere lengthening early in development
-
Liu L, Bailey SM, Okuka M, Munoz P, Li C, et al: Telomere lengthening early in development. Nat Cell Biol 2007;9:1436-1441.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1436-1441
-
-
Liu, L.1
Bailey, S.M.2
Okuka, M.3
Munoz, P.4
Li, C.5
-
74
-
-
80053229934
-
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes
-
Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, et al: Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. Am J Pathol 2011;179:1608-1615.
-
(2011)
Am J Pathol
, vol.179
, pp. 1608-1615
-
-
Heaphy, C.M.1
Subhawong, A.P.2
Hong, S.M.3
Goggins, M.G.4
Montgomery, E.A.5
-
75
-
-
80052019968
-
Comparative biology of mammalian telomeres: Hypotheses on ancestral states and the roles of telomeres in longevity determination
-
Gomes NM, Ryder OA, Houck ML, Charter SJ, Walker W, et al: Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination. Aging Cell 2011;10:761-768.
-
(2011)
Aging Cell
, vol.10
, pp. 761-768
-
-
Gomes, N.M.1
Ryder, O.A.2
Houck, M.L.3
Charter, S.J.4
Walker, W.5
-
76
-
-
58149341744
-
Coevolution of telom-erase activity and body mass in mammals: From mice to beavers
-
Gorbunova V, Seluanov A: Coevolution of telom-erase activity and body mass in mammals: from mice to beavers. Mech Ageing Dev 2009;130:3-9.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 3-9
-
-
Gorbunova, V.1
Seluanov, A.2
-
77
-
-
40349085766
-
The longest telomeres: A general signature of adult stem cell compartments
-
Flores I, Canela A, Vera E, Tejera A, Cotsarelis G, Blasco MA: The longest telomeres: a general signature of adult stem cell compartments. Genes Dev 2008;22:654-667.
-
(2008)
Genes Dev
, vol.22
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
78
-
-
55449122193
-
Telomerase reverse transcriptase delays aging in cancer-resistant mice
-
Tomas-Loba A, Flores I, Fernandez-Marcos PJ, Cayuela ML, Maraver A, et al: Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell 2008;135:609-622.
-
(2008)
Cell
, vol.135
, pp. 609-622
-
-
Tomas-Loba, A.1
Flores, I.2
Fernandez-Marcos, P.J.3
Cayuela, M.L.4
Maraver, A.5
-
80
-
-
67650079362
-
Syndromes of telomere shortening
-
Armanios M: Syndromes of telomere shortening. Annu Rev Genomics Hum Genet 2009;10:45-61.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 45-61
-
-
Armanios, M.1
-
81
-
-
79960147671
-
The human TTAGGG repeat factors 1 and 2 bind to A subset of interstitial telo-meric sequences and satellite repeats
-
Simonet T, Zaragosi LE, Philippe C, Lebrigand K, Schouteden C, et al: The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telo-meric sequences and satellite repeats. Cell Res 2011;21:1028-1038.
-
(2011)
Cell Res
, vol.21
, pp. 1028-1038
-
-
Simonet, T.1
Zaragosi, L.E.2
Philippe, C.3
Lebrigand, K.4
Schouteden, C.5
-
82
-
-
67650065306
-
Telomerase modulates Wnt signalling by association with target gene chromatin
-
Park JI, Venteicher AS, Hong J Y, Choi J, Jun S, et al: Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 2009;460:66-72.
-
(2009)
Nature
, vol.460
, pp. 66-72
-
-
Park, J.I.1
Venteicher, A.S.2
Hong, J.Y.3
Choi, J.4
Jun, S.5
-
83
-
-
77958460546
-
Taking apart Rap1: An adaptor protein with telomeric and non-telomeric functions
-
Kabir S, Sfeir A, de Lange T: Taking apart Rap1: an adaptor protein with telomeric and non-telomeric functions. Cell Cycle 2011;9:4061-4067.
-
(2011)
Cell Cycle
, vol.9
, pp. 4061-4067
-
-
Kabir, S.1
Sfeir, A.2
De Lange, T.3
|