Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice

Experimental Gerontology

Volumn 65, Issue , 2015, Pages 69-78

  Ettcheto, Miren ^a,c   Petrov, Dmitry ^a,c   Pedrós, Ignacio ^b,c   de Lemos, Luisa ^a,c   Pallàs, Mercè ^a,c   Alegret, Marta ^a,d   Laguna, Juan Carlos ^a,d   Folch, Jaume ^b,c   Camins, Antoni ^a,c,e  

^a UNIVERSITY OF BARCELONA   (Spain)

^b FACULTAT DE MEDICINA I CIÈNCIES DE LA SALUT   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d Instituto de Salud Carlos III   (Spain)

^e UNIVERSIDAD NACIONAL DE LOJA   (Ecuador)

Author keywords

Alzheimer's disease; APP PS1; Cholesterol; Hippocampus; LDLR ; OXPHOS

Indexed keywords

ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; ADENYLATE KINASE; AMYLOID PRECURSOR PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; INSULINASE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; NERVE GROWTH FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROOPIOMELANOCORTIN; PROOPIOMELANOCORTIN ALPHA; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 1; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE AMP ACTIVATED ALPHA 1 CATALYTIC SUBUNIT OF AMPK; UNCLASSIFIED DRUG; CHOLESTEROL; CREB1 PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ACTIVITY REGULATED CYTOSKELETAL ASSOCIATED PROTEIN GENE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN REGION; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE COURSE; DOWN REGULATION; FBJ OSTEOSARCOMA GENE; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HIPPOCAMPUS; HYPERCHOLESTEROLEMIA; LIPID METABOLISM; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NERVE DEGENERATION; NONHUMAN; ONCOGENE; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; COGNITIVE DEFECT; COMPLICATION; GENETICS; KNOCKOUT MOUSE; MEMORY DISORDER; METABOLISM;

ANIMALIA; MUS;

ALZHEIMER DISEASE; ANIMALS; CHOLESTEROL; COGNITION DISORDERS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HIPPOCAMPUS; HYPERCHOLESTEROLEMIA; INSULYSIN; MALE; MEMORY DISORDERS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; RECEPTORS, LDL; TRANSCRIPTION FACTORS;

EID: 84925664513     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2015.03.010     Document Type: Article

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