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Volumn 48, Issue , 2014, Pages 123-135

Prediabetes-induced vascular alterations exacerbate central pathology in APPswe/PS1dE9 mice

Author keywords

Alzheimer's disease; Amyloid ; Haemorrhage; Hyperinsulinemia; Insulin degrading enzyme; Microglia; Neprilysin; Prediabetes; Tau

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; INSULINASE; MEMBRANE METALLOENDOPEPTIDASE; TAU PROTEIN; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; PRESENILIN 1, MOUSE;

EID: 84904874633     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2014.06.005     Document Type: Article
Times cited : (47)

References (67)
  • 1
    • 84876823225 scopus 로고    scopus 로고
    • Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease
    • Aso E., Semakova J., Joda L., Semak V., Halbaut L., Calpena A., Escolano C., Perales J.C., Ferrer I. Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease. Curr. Alzheimer Res. 2013, 10:290-297.
    • (2013) Curr. Alzheimer Res. , vol.10 , pp. 290-297
    • Aso, E.1    Semakova, J.2    Joda, L.3    Semak, V.4    Halbaut, L.5    Calpena, A.6    Escolano, C.7    Perales, J.C.8    Ferrer, I.9
  • 3
    • 84860452103 scopus 로고    scopus 로고
    • Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo
    • Becker K., Freude S., Zemva J., Stohr O., Krone W., Schubert M. Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo. Neurosci. Lett. 2012, 516:306-310.
    • (2012) Neurosci. Lett. , vol.516 , pp. 306-310
    • Becker, K.1    Freude, S.2    Zemva, J.3    Stohr, O.4    Krone, W.5    Schubert, M.6
  • 4
    • 84875226541 scopus 로고    scopus 로고
    • A ketogenic diet improves motor performance but does not affect beta-amyloid levels in a mouse model of Alzheimer's disease
    • Beckett T.L., Studzinski C.M., Keller J.N., Paul Murphy M., Niedowicz D.M. A ketogenic diet improves motor performance but does not affect beta-amyloid levels in a mouse model of Alzheimer's disease. Brain Res. 2013, 1505:61-67.
    • (2013) Brain Res. , vol.1505 , pp. 61-67
    • Beckett, T.L.1    Studzinski, C.M.2    Keller, J.N.3    Paul Murphy, M.4    Niedowicz, D.M.5
  • 5
    • 79960555700 scopus 로고    scopus 로고
    • Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
    • Bosco D., Fava A., Plastino M., Montalcini T., Pujia A. Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. J. Cell. Mol. Med. 2011, 15:1807-1821.
    • (2011) J. Cell. Mol. Med. , vol.15 , pp. 1807-1821
    • Bosco, D.1    Fava, A.2    Plastino, M.3    Montalcini, T.4    Pujia, A.5
  • 6
    • 84867581171 scopus 로고    scopus 로고
    • High-fat diet ameliorates neurological deficits caused by defective astrocyte lipid metabolism
    • Camargo N., Brouwers J.F., Loos M., Gutmann D.H., Smit A.B., Verheijen M.H. High-fat diet ameliorates neurological deficits caused by defective astrocyte lipid metabolism. FASEB J. 2012, 26:4302-4315.
    • (2012) FASEB J. , vol.26 , pp. 4302-4315
    • Camargo, N.1    Brouwers, J.F.2    Loos, M.3    Gutmann, D.H.4    Smit, A.B.5    Verheijen, M.H.6
  • 8
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged
    • Craft S. The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged. Arch. Neurol. 2009, 66:300-305.
    • (2009) Arch. Neurol. , vol.66 , pp. 300-305
    • Craft, S.1
  • 9
    • 84878200358 scopus 로고    scopus 로고
    • A truncated splice-variant of the FcepsilonRIbeta receptor subunit is critical for microtubule formation and degranulation in mast cells
    • Cruse G., Beaven M.A., Ashmole I., Bradding P., Gilfillan A.M., Metcalfe D.D. A truncated splice-variant of the FcepsilonRIbeta receptor subunit is critical for microtubule formation and degranulation in mast cells. Immunity 2013, 38:906-917.
    • (2013) Immunity , vol.38 , pp. 906-917
    • Cruse, G.1    Beaven, M.A.2    Ashmole, I.3    Bradding, P.4    Gilfillan, A.M.5    Metcalfe, D.D.6
  • 10
    • 33748755428 scopus 로고    scopus 로고
    • Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease
    • de la Monte S.M., Tong M., Lester-Coll N., Plater M., Wands J.R. Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease. J. Alzheimers Dis. 2006, 10:89-109.
    • (2006) J. Alzheimers Dis. , vol.10 , pp. 89-109
    • de la Monte, S.M.1    Tong, M.2    Lester-Coll, N.3    Plater, M.4    Wands, J.R.5
  • 11
    • 27844442718 scopus 로고    scopus 로고
    • Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention
    • Eckman E.A., Eckman C.B. Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention. Biochem. Soc. Trans. 2005, 33:1101-1105.
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 1101-1105
    • Eckman, E.A.1    Eckman, C.B.2
  • 13
    • 33847783428 scopus 로고    scopus 로고
    • Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene
    • Fendrick S.E., Xue Q.S., Streit W.J. Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene. J. Neuroinflammation 2007, 4:9.
    • (2007) J. Neuroinflammation , vol.4 , pp. 9
    • Fendrick, S.E.1    Xue, Q.S.2    Streit, W.J.3
  • 15
    • 84866357260 scopus 로고    scopus 로고
    • Impaired performance of female APP/PS1 mice in the Morris water maze is coupled with increased Abeta accumulation and microglial activation
    • Gallagher J.J., Minogue A.M., Lynch M.A. Impaired performance of female APP/PS1 mice in the Morris water maze is coupled with increased Abeta accumulation and microglial activation. Neurodegener. Dis. 2013, 11:33-41.
    • (2013) Neurodegener. Dis. , vol.11 , pp. 33-41
    • Gallagher, J.J.1    Minogue, A.M.2    Lynch, M.A.3
  • 16
    • 84904901303 scopus 로고    scopus 로고
    • Streptozotocin as a tool to induce central pathology and cognitive impairment in rodents
    • Nova Science Publishers, Inc., Hauppauge, NY, E.L. Gauthier (Ed.)
    • Garcia-Alloza M. Streptozotocin as a tool to induce central pathology and cognitive impairment in rodents. Streptozotocin: Uses, Mechanism of Action and Side Effects 2014, Nova Science Publishers, Inc., Hauppauge, NY. E.L. Gauthier (Ed.).
    • (2014) Streptozotocin: Uses, Mechanism of Action and Side Effects
    • Garcia-Alloza, M.1
  • 20
    • 84876354074 scopus 로고    scopus 로고
    • Understanding and treating vascular cognitive impairment
    • Gorelick P.B., Nyenhuis D. Understanding and treating vascular cognitive impairment. Continuum (Minneap Minn) 2013, 19:425-437.
    • (2013) Continuum (Minneap Minn) , vol.19 , pp. 425-437
    • Gorelick, P.B.1    Nyenhuis, D.2
  • 22
    • 84873617421 scopus 로고    scopus 로고
    • Beta-alanyl-l-histidine rescues cognitive deficits caused by feeding a high fat diet in a transgenic mouse model of Alzheimer's disease
    • Herculano B., Tamura M., Ohba A., Shimatani M., Kutsuna N., Hisatsune T. Beta-alanyl-l-histidine rescues cognitive deficits caused by feeding a high fat diet in a transgenic mouse model of Alzheimer's disease. J. Alzheimers Dis. 2013, 33:983-997.
    • (2013) J. Alzheimers Dis. , vol.33 , pp. 983-997
    • Herculano, B.1    Tamura, M.2    Ohba, A.3    Shimatani, M.4    Kutsuna, N.5    Hisatsune, T.6
  • 23
    • 84863091207 scopus 로고    scopus 로고
    • Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression
    • Heyward F.D., Walton R.G., Carle M.S., Coleman M.A., Garvey W.T., Sweatt J.D. Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression. Neurobiol. Learn. Mem. 2012, 98:25-32.
    • (2012) Neurobiol. Learn. Mem. , vol.98 , pp. 25-32
    • Heyward, F.D.1    Walton, R.G.2    Carle, M.S.3    Coleman, M.A.4    Garvey, W.T.5    Sweatt, J.D.6
  • 25
    • 80051569682 scopus 로고    scopus 로고
    • Amyloid-dependent and amyloid-independent stages of Alzheimer disease
    • Hyman B.T. Amyloid-dependent and amyloid-independent stages of Alzheimer disease. Arch. Neurol. 2011, 68:1062-1064.
    • (2011) Arch. Neurol. , vol.68 , pp. 1062-1064
    • Hyman, B.T.1
  • 28
    • 0036300343 scopus 로고    scopus 로고
    • Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention
    • Kivipelto M., Laakso M.P., Tuomilehto J., Nissinen A., Soininen H. Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention. CNS Drugs 2002, 16:435-444.
    • (2002) CNS Drugs , vol.16 , pp. 435-444
    • Kivipelto, M.1    Laakso, M.P.2    Tuomilehto, J.3    Nissinen, A.4    Soininen, H.5
  • 29
    • 84899898904 scopus 로고    scopus 로고
    • High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
    • Knight E.M., Martins I.V., Gumusgoz S., Allan S.M., Lawrence C.B. High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology. Neurobiol. Aging 2014, 35:1821-1832.
    • (2014) Neurobiol. Aging , vol.35 , pp. 1821-1832
    • Knight, E.M.1    Martins, I.V.2    Gumusgoz, S.3    Allan, S.M.4    Lawrence, C.B.5
  • 34
    • 5344256250 scopus 로고    scopus 로고
    • Hyperinsulinemia and risk of Alzheimer disease
    • Luchsinger J.A., Tang M.X., Shea S., Mayeux R. Hyperinsulinemia and risk of Alzheimer disease. Neurology 2004, 63:1187-1192.
    • (2004) Neurology , vol.63 , pp. 1187-1192
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 38
    • 33751218916 scopus 로고    scopus 로고
    • Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice
    • Mielke J.G., Nicolitch K., Avellaneda V., Earlam K., Ahuja T., Mealing G., Messier C. Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice. Behav. Brain Res. 2006, 175:374-382.
    • (2006) Behav. Brain Res. , vol.175 , pp. 374-382
    • Mielke, J.G.1    Nicolitch, K.2    Avellaneda, V.3    Earlam, K.4    Ahuja, T.5    Mealing, G.6    Messier, C.7
  • 39
    • 33744982670 scopus 로고    scopus 로고
    • Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice
    • Morgan D. Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice. Neurochem. Int. 2006, 49:190-194.
    • (2006) Neurochem. Int. , vol.49 , pp. 190-194
    • Morgan, D.1
  • 42
    • 49749087978 scopus 로고    scopus 로고
    • A review of islet of Langerhans degeneration in rodent models of type 2 diabetes
    • Nugent D.A., Smith D.M., Jones H.B. A review of islet of Langerhans degeneration in rodent models of type 2 diabetes. Toxicol. Pathol. 2008, 36:529-551.
    • (2008) Toxicol. Pathol. , vol.36 , pp. 529-551
    • Nugent, D.A.1    Smith, D.M.2    Jones, H.B.3
  • 43
    • 33748608244 scopus 로고    scopus 로고
    • Vascular cognitive impairment
    • O'Brien J.T. Vascular cognitive impairment. Am. J. Geriatr. Psychiatry 2006, 14:724-733.
    • (2006) Am. J. Geriatr. Psychiatry , vol.14 , pp. 724-733
    • O'Brien, J.T.1
  • 46
    • 84880399455 scopus 로고    scopus 로고
    • Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-beta and cerebrovascular pathology
    • Papadopoulos P., Rosa-Neto P., Rochford J., Hamel E. Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-beta and cerebrovascular pathology. PLOS ONE 2013, 8:e68612.
    • (2013) PLOS ONE , vol.8
    • Papadopoulos, P.1    Rosa-Neto, P.2    Rochford, J.3    Hamel, E.4
  • 48
    • 47549098083 scopus 로고    scopus 로고
    • Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats
    • Pathan A.R., Gaikwad A.B., Viswanad B., Ramarao P. Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats. Eur. J. Pharmacol. 2008, 589:176-179.
    • (2008) Eur. J. Pharmacol. , vol.589 , pp. 176-179
    • Pathan, A.R.1    Gaikwad, A.B.2    Viswanad, B.3    Ramarao, P.4
  • 49
    • 84874123482 scopus 로고    scopus 로고
    • Cerebral neovascularization and remodeling patterns in two different models of type 2 diabetes
    • Prakash R., Johnson M., Fagan S.C., Ergul A. Cerebral neovascularization and remodeling patterns in two different models of type 2 diabetes. PLOS ONE 2013, 8:e56264.
    • (2013) PLOS ONE , vol.8
    • Prakash, R.1    Johnson, M.2    Fagan, S.C.3    Ergul, A.4
  • 50
    • 84896725927 scopus 로고    scopus 로고
    • Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice
    • Ramos-Rodriguez J.J., Molina-Gil S., Rey-Brea R., Berrocoso E., Garcia-Alloza M. Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice. PLOS ONE 2013, 8:e79947.
    • (2013) PLOS ONE , vol.8
    • Ramos-Rodriguez, J.J.1    Molina-Gil, S.2    Rey-Brea, R.3    Berrocoso, E.4    Garcia-Alloza, M.5
  • 53
    • 33846057321 scopus 로고    scopus 로고
    • The metabolic syndrome and Alzheimer disease
    • Razay G., Vreugdenhil A., Wilcock G. The metabolic syndrome and Alzheimer disease. Arch. Neurol. 2007, 64:93-96.
    • (2007) Arch. Neurol. , vol.64 , pp. 93-96
    • Razay, G.1    Vreugdenhil, A.2    Wilcock, G.3
  • 54
    • 0030772890 scopus 로고    scopus 로고
    • Cholinergic activity and amyloid precursor protein metabolism
    • Roberson M.R., Harrell L.E. Cholinergic activity and amyloid precursor protein metabolism. Brain Res. Brain Res. Rev. 1997, 25:50-69.
    • (1997) Brain Res. Brain Res. Rev. , vol.25 , pp. 50-69
    • Roberson, M.R.1    Harrell, L.E.2
  • 56
    • 84878259064 scopus 로고    scopus 로고
    • Apelin inhibits diet-induced obesity by enhancing lymphatic and blood vessel integrity
    • Sawane M., Kajiya K., Kidoya H., Takagi M., Muramatsu F., Takakura N. Apelin inhibits diet-induced obesity by enhancing lymphatic and blood vessel integrity. Diabetes 2013, 62:1970-1980.
    • (2013) Diabetes , vol.62 , pp. 1970-1980
    • Sawane, M.1    Kajiya, K.2    Kidoya, H.3    Takagi, M.4    Muramatsu, F.5    Takakura, N.6
  • 57
    • 33750445930 scopus 로고    scopus 로고
    • The significance of the cholinergic system in the brain during aging and in Alzheimer's disease
    • Schliebs R., Arendt T. The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. J. Neural Transm. 2006, 113:1625-1644.
    • (2006) J. Neural Transm. , vol.113 , pp. 1625-1644
    • Schliebs, R.1    Arendt, T.2
  • 60
    • 0037171095 scopus 로고    scopus 로고
    • Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice
    • Shie F.S., Jin L.W., Cook D.G., Leverenz J.B., LeBoeuf R.C. Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport 2002, 13:455-459.
    • (2002) Neuroreport , vol.13 , pp. 455-459
    • Shie, F.S.1    Jin, L.W.2    Cook, D.G.3    Leverenz, J.B.4    LeBoeuf, R.C.5
  • 61
    • 84870213683 scopus 로고    scopus 로고
    • Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via the inhibition of mammalian target of rapamycin pathway
    • Son S.M., Song H., Byun J., Park K.S., Jang H.C., Park Y.J., Mook-Jung I. Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via the inhibition of mammalian target of rapamycin pathway. Diabetes 2012, 61:3126-3138.
    • (2012) Diabetes , vol.61 , pp. 3126-3138
    • Son, S.M.1    Song, H.2    Byun, J.3    Park, K.S.4    Jang, H.C.5    Park, Y.J.6    Mook-Jung, I.7
  • 65
    • 84860903756 scopus 로고    scopus 로고
    • Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study
    • van Himbergen T.M., Beiser A.S., Ai M., Seshadri S., Otokozawa S., Au R., Thongtang N., Wolf P.A., Schaefer E.J. Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study. Arch. Neurol. 2012, 69:594-600.
    • (2012) Arch. Neurol. , vol.69 , pp. 594-600
    • van Himbergen, T.M.1    Beiser, A.S.2    Ai, M.3    Seshadri, S.4    Otokozawa, S.5    Au, R.6    Thongtang, N.7    Wolf, P.A.8    Schaefer, E.J.9
  • 66
    • 41149157623 scopus 로고    scopus 로고
    • Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease
    • Weller R.O., Subash M., Preston S.D., Mazanti I., Carare R.O. Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease. Brain Pathol. 2008, 18:253-266.
    • (2008) Brain Pathol. , vol.18 , pp. 253-266
    • Weller, R.O.1    Subash, M.2    Preston, S.D.3    Mazanti, I.4    Carare, R.O.5
  • 67
    • 84890808796 scopus 로고    scopus 로고
    • Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes
    • Yang Y., Zhang J., Ma D., Zhang M., Hu S., Shao S., Gong C.X. Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes. J. Alzheimers Dis. 2013, 37:637-648.
    • (2013) J. Alzheimers Dis. , vol.37 , pp. 637-648
    • Yang, Y.1    Zhang, J.2    Ma, D.3    Zhang, M.4    Hu, S.5    Shao, S.6    Gong, C.X.7


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