-
1
-
-
63549125243
-
Cardiovascular risk factors and dementia mortality: 40 years of follow-up in the Seven Countries Study
-
19251275 10.1016/j.jns.2009.02.004
-
Alonso A, Jacobs DR Jr, Menotti A, Nissinen A, Dontas A, Kafatos A, Kromhout D (2009) Cardiovascular risk factors and dementia mortality: 40 years of follow-up in the Seven Countries Study. J Neurol Sci 280:79-83
-
(2009)
J Neurol Sci
, vol.280
, pp. 79-83
-
-
Alonso, A.1
Jacobs, Jr.D.R.2
Menotti, A.3
Nissinen, A.4
Dontas, A.5
Kafatos, A.6
Kromhout, D.7
-
2
-
-
68049112355
-
Object location memory in mice: Pharmacological validation and further evidence of hippocampal CA1 participation
-
19523494 10.1016/j.bbr.2009.06.005
-
Assini FL, Duzzioni M, Takahashi RN (2009) Object location memory in mice: pharmacological validation and further evidence of hippocampal CA1 participation. Behav Brain Res 204:206-211
-
(2009)
Behav Brain Res
, vol.204
, pp. 206-211
-
-
Assini, F.L.1
Duzzioni, M.2
Takahashi, R.N.3
-
3
-
-
23644442259
-
Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid
-
16081359 10.1080/00365510510025746
-
Babiker A, Dzeletovic S, Wiklund B, Pettersson N, Salonen J, Nyyssonen K, Eriksson M, Diczfalusy U, Bjorkhem I (2005) Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid. Scand J Clin Lab Invest 65:365-375
-
(2005)
Scand J Clin Lab Invest
, vol.65
, pp. 365-375
-
-
Babiker, A.1
Dzeletovic, S.2
Wiklund, B.3
Pettersson, N.4
Salonen, J.5
Nyyssonen, K.6
Eriksson, M.7
Diczfalusy, U.8
Bjorkhem, I.9
-
4
-
-
0036736781
-
Do oxysterols control cholesterol homeostasis?
-
151135 12235099 10.1172/JCI0216388
-
Bjorkhem I (2002) Do oxysterols control cholesterol homeostasis? J Clin Invest 110:725-730
-
(2002)
J Clin Invest
, vol.110
, pp. 725-730
-
-
Bjorkhem, I.1
-
5
-
-
33846362273
-
Oxysterols and Alzheimer's disease
-
16866910 10.1111/j.1600-0404.2006.00684.x
-
Bjorkhem I, Heverin M, Leoni V, Meaney S, Diczfalusy U (2006) Oxysterols and Alzheimer's disease. Acta Neurol Scand Suppl 185:43-49
-
(2006)
Acta Neurol Scand Suppl
, vol.185
, pp. 43-49
-
-
Bjorkhem, I.1
Heverin, M.2
Leoni, V.3
Meaney, S.4
Diczfalusy, U.5
-
6
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
8626795 10.1074/jbc.271.8.4436
-
Bodovitz S, Klein WL (1996) Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271:4436-4440
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
7
-
-
0038209646
-
Serum cholesterol levels modulate long-term efficacy of cholinesterase inhibitors in Alzheimer disease
-
12770699 10.1016/S0304-3940(03)00336-7
-
Borroni B, Pettenati C, Bordonali T, Akkawi N, Di Luca M, Padovani A (2003) Serum cholesterol levels modulate long-term efficacy of cholinesterase inhibitors in Alzheimer disease. Neurosci Lett 343:213-215
-
(2003)
Neurosci Lett
, vol.343
, pp. 213-215
-
-
Borroni, B.1
Pettenati, C.2
Bordonali, T.3
Akkawi, N.4
Di Luca, M.5
Padovani, A.6
-
8
-
-
0022272480
-
Glutathione reductase
-
3003504 10.1016/S0076-6879(85)13062-4
-
Carlberg I, Mannervik B (1985) Glutathione reductase. Methods Enzymol 113:484-490
-
(1985)
Methods Enzymol
, vol.113
, pp. 484-490
-
-
Carlberg, I.1
Mannervik, B.2
-
9
-
-
42649109113
-
Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease
-
10.1186/1742-2094-5-12
-
Chen X, Gawryluk JW, Wagener JF, Ghribi O, Geiger JD (2008) Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. J Neuroinflamm 5:12
-
(2008)
J Neuroinflamm
, vol.5
, pp. 12
-
-
Chen, X.1
Gawryluk, J.W.2
Wagener, J.F.3
Ghribi, O.4
Geiger, J.D.5
-
10
-
-
77956254932
-
The PRiMA-linked cholinesterase tetramers are assembled from homodimers: Hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain
-
2930726 20566626 10.1074/jbc.M110.113647
-
Chen VP, Xie HQ, Chan WK, Leung KW, Chan GK, Choi RC, Bon S, Massoulie J, Tsim KW (2010) The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain. J Biol Chem 285:27265-27278
-
(2010)
J Biol Chem
, vol.285
, pp. 27265-27278
-
-
Chen, V.P.1
Xie, H.Q.2
Chan, W.K.3
Leung, K.W.4
Chan, G.K.5
Choi, R.C.6
Bon, S.7
Massoulie, J.8
Tsim, K.W.9
-
11
-
-
41549107577
-
The basic biology of BACE1: A key therapeutic target for Alzheimer's disease
-
2647160 19415126 10.2174/138920207783769512
-
Cole SL, Vassar R (2007) The basic biology of BACE1: a key therapeutic target for Alzheimer's disease. Curr Genomics 8:509-530
-
(2007)
Curr Genomics
, vol.8
, pp. 509-530
-
-
Cole, S.L.1
Vassar, R.2
-
12
-
-
33645299023
-
The involvement of lipid rafts in Alzheimer's disease
-
16611586 10.1080/09687860500496417
-
Cordy JM, Hooper NM, Turner AJ (2006) The involvement of lipid rafts in Alzheimer's disease. Mol Membr Biol 23:111-122
-
(2006)
Mol Membr Biol
, vol.23
, pp. 111-122
-
-
Cordy, J.M.1
Hooper, N.M.2
Turner, A.J.3
-
13
-
-
84983723316
-
Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro
-
18440006 10.1016/j.atherosclerosis.2008.02.030
-
de Bem AF, Farina M, Portella Rde L, Nogueira CW, Dinis TC, Laranjinha JA, Almeida LM, Rocha JB (2008) Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro. Atherosclerosis 201:92-100
-
(2008)
Atherosclerosis
, vol.201
, pp. 92-100
-
-
De Bem, A.F.1
Farina, M.2
Portella Rde, L.3
Nogueira, C.W.4
Dinis, T.C.5
Laranjinha, J.A.6
Almeida, L.M.7
Rocha, J.B.8
-
14
-
-
82855172098
-
Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: Relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress
-
21945034 10.1016/j.neuroscience.2011.09.009
-
de Oliveira J, Hort MA, Moreira EL, Glaser V, Ribeiro-do-Valle RM, Prediger RD, Farina M, Latini A, de Bem AF (2011) Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress. Neuroscience 197:99-106
-
(2011)
Neuroscience
, vol.197
, pp. 99-106
-
-
De Oliveira, J.1
Hort, M.A.2
Moreira, E.L.3
Glaser, V.4
Ribeiro-Do-Valle, R.M.5
Prediger, R.D.6
Farina, M.7
Latini, A.8
De Bem, A.F.9
-
15
-
-
79955745304
-
The cholinergic system and spatial learning
-
21108971 10.1016/j.bbr.2010.11.036
-
Deiana S, Platt B, Riedel G (2011) The cholinergic system and spatial learning. Behav Brain Res 221:389-411
-
(2011)
Behav Brain Res
, vol.221
, pp. 389-411
-
-
Deiana, S.1
Platt, B.2
Riedel, G.3
-
16
-
-
45949106221
-
Atherogenic diet-induced hepatitis is partially dependent on murine TLR4
-
18334542 10.1189/jlb.0607390
-
Desai MS, Mariscalco MM, Tawil A, Vallejo JG, Smith CW (2008) Atherogenic diet-induced hepatitis is partially dependent on murine TLR4. J Leukoc Biol 83:1336-1344
-
(2008)
J Leukoc Biol
, vol.83
, pp. 1336-1344
-
-
Desai, M.S.1
Mariscalco, M.M.2
Tawil, A.3
Vallejo, J.G.4
Smith, C.W.5
-
17
-
-
0035083555
-
Cholesterol metabolism in the brain
-
11264981 10.1097/00041433-200104000-00003
-
Dietschy JM, Turley SD (2001) Cholesterol metabolism in the brain. Curr Opin Lipidol 12:105-112
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 105-112
-
-
Dietschy, J.M.1
Turley, S.D.2
-
18
-
-
0038636003
-
Glutathione pathways in the brain
-
12751781 10.1515/BC.2003.059
-
Dringen R, Hirrlinger J (2003) Glutathione pathways in the brain. Biol Chem 384:505-516
-
(2003)
Biol Chem
, vol.384
, pp. 505-516
-
-
Dringen, R.1
Hirrlinger, J.2
-
19
-
-
0026763167
-
Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: Comparison with interleukin-1
-
1602402
-
Dunn AJ (1992) Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1. J Pharmacol Exp Ther 261:964-969
-
(1992)
J Pharmacol Exp Ther
, vol.261
, pp. 964-969
-
-
Dunn, A.J.1
-
20
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
2172747 12515826 10.1083/jcb.200207113
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K (2003) Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 160:113-123
-
(2003)
J Cell Biol
, vol.160
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
21
-
-
3042934967
-
Tissue sulfhydryl groups
-
13650640 10.1016/0003-9861(59)90090-6
-
Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70-77
-
(1959)
Arch Biochem Biophys
, vol.82
, pp. 70-77
-
-
Ellman, G.L.1
-
22
-
-
33644811612
-
A new and rapid colorimetric determination of acetylcholinesterase activity
-
13726518 10.1016/0006-2952(61)90145-9
-
Ellman GL, Courtney KD, Andres V Jr, Feather-Stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88-95
-
(1961)
Biochem Pharmacol
, vol.7
, pp. 88-95
-
-
Ellman, G.L.1
Courtney, K.D.2
Andres, Jr.V.3
Feather-Stone, R.M.4
-
23
-
-
77953728876
-
Oxidative stress impairs learning and memory in apoE knockout mice
-
2916228 20457176 10.1016/j.pbb.2010.05.003
-
Evola M, Hall A, Wall T, Young A, Grammas P (2010) Oxidative stress impairs learning and memory in apoE knockout mice. Pharmacol Biochem Behav 96:181-186
-
(2010)
Pharmacol Biochem Behav
, vol.96
, pp. 181-186
-
-
Evola, M.1
Hall, A.2
Wall, T.3
Young, A.4
Grammas, P.5
-
24
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
10501560 10.1097/00001756-199906030-00014
-
Frears ER, Stephens DJ, Walters CE, Davies H, Austen BM (1999) The role of cholesterol in the biosynthesis of beta-amyloid. NeuroReport 10:1699-1705
-
(1999)
NeuroReport
, vol.10
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
25
-
-
84871442933
-
Effects of statins and cholesterol on memory functions on mice
-
23065075 10.1007/s11011-012-9343-5
-
Ghodke RM, Tour N, Devi K (2012) Effects of statins and cholesterol on memory functions on mice. Metab Brain Dis 27:443-451
-
(2012)
Metab Brain Dis
, vol.27
, pp. 443-451
-
-
Ghodke, R.M.1
Tour, N.2
Devi, K.3
-
26
-
-
33746299216
-
High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus
-
16696972 10.1016/j.expneurol.2006.03.019
-
Ghribi O, Larsen B, Schrag M, Herman MM (2006) High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. Exp Neurol 200:460-467
-
(2006)
Exp Neurol
, vol.200
, pp. 460-467
-
-
Ghribi, O.1
Larsen, B.2
Schrag, M.3
Herman, M.M.4
-
27
-
-
77956216232
-
Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis
-
2882324 20544018 10.1371/journal.pone.0010977
-
Guillaumot P, Luquain C, Malek M, Huber AL, Brugiere S, Garin J, Grunwald D, Regnier D, Petrilli V, Lefai E, Manie SN (2010) Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis. PLoS ONE 5:e10977
-
(2010)
PLoS ONE
, vol.5
, pp. 10977
-
-
Guillaumot, P.1
Luquain, C.2
Malek, M.3
Huber, A.L.4
Brugiere, S.5
Garin, J.6
Grunwald, D.7
Regnier, D.8
Petrilli, V.9
Lefai, E.10
Manie, S.N.11
-
28
-
-
0027517309
-
Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
-
8370768 10.1016/0165-5728(93)90027-V
-
Gutierrez EG, Banks WA, Kastin AJ (1993) Murine tumor necrosis factor alpha is transported from blood to brain in the mouse. J Neuroimmunol 47:169-176
-
(1993)
J Neuroimmunol
, vol.47
, pp. 169-176
-
-
Gutierrez, E.G.1
Banks, W.A.2
Kastin, A.J.3
-
29
-
-
23744498856
-
Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain
-
15741649 10.1194/jlr.M500024-JLR200
-
Heverin M, Meaney S, Lutjohann D, Diczfalusy U, Wahren J, Bjorkhem I (2005) Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain. J Lipid Res 46:1047-1052
-
(2005)
J Lipid Res
, vol.46
, pp. 1047-1052
-
-
Heverin, M.1
Meaney, S.2
Lutjohann, D.3
Diczfalusy, U.4
Wahren, J.5
Bjorkhem, I.6
-
30
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
-
9632729 10.1074/jbc.273.26.16576
-
Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD, Maeda N, Siman R, Greenberg BD, Scott RW, Flood DG (1998) Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J Biol Chem 273:16576-16582
-
(1998)
J Biol Chem
, vol.273
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maeda, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
31
-
-
78650119727
-
The relationship between aquaporin-4 expression and blood-brain and spinal cord barrier permeability following experimental autoimmune encephalomyelitis in the rat
-
10.1002/ar.21286
-
Huang XN, Wang WZ, Fu J, Wang HB (2011) The relationship between aquaporin-4 expression and blood-brain and spinal cord barrier permeability following experimental autoimmune encephalomyelitis in the rat. Anat Rec (Hoboken) 294:46-54
-
(2011)
Anat Rec (Hoboken)
, vol.294
, pp. 46-54
-
-
Huang, X.N.1
Wang, W.Z.2
Fu, J.3
Wang, H.B.4
-
32
-
-
84869506862
-
Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons
-
3431446 22580286 10.1016/j.lfs.2012.04.039
-
Hui L, Chen X, Geiger JD (2012) Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons. Life Sci 91:1159-1168
-
(2012)
Life Sci
, vol.91
, pp. 1159-1168
-
-
Hui, L.1
Chen, X.2
Geiger, J.D.3
-
33
-
-
79954986242
-
Oxysterol derivatives of cholesterol in neurodegenerative disorders
-
21428891 10.2174/092986711795328445
-
Jeitner TM, Voloshyna I, Reiss AB (2011) Oxysterol derivatives of cholesterol in neurodegenerative disorders. Curr Med Chem 18:1515-1525
-
(2011)
Curr Med Chem
, vol.18
, pp. 1515-1525
-
-
Jeitner, T.M.1
Voloshyna, I.2
Reiss, A.B.3
-
34
-
-
70350443610
-
Influence of hypercholesterolemia and hypertension on the integrity of the blood-brain barrier in rats
-
19922391 10.1080/14647270802336650
-
Kalayci R, Kaya M, Uzun H, Bilgic B, Ahishali B, Arican N, Elmas I, Kucuk M (2009) Influence of hypercholesterolemia and hypertension on the integrity of the blood-brain barrier in rats. Int J Neurosci 119:1881-1904
-
(2009)
Int J Neurosci
, vol.119
, pp. 1881-1904
-
-
Kalayci, R.1
Kaya, M.2
Uzun, H.3
Bilgic, B.4
Ahishali, B.5
Arican, N.6
Elmas, I.7
Kucuk, M.8
-
35
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
-
32306 11408299 10.1136/bmj.322.7300.1447
-
Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A (2001) Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ 322:1447-1451
-
(2001)
BMJ
, vol.322
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.L.2
Laakso, M.P.3
Hanninen, T.4
Hallikainen, M.5
Alhainen, K.6
Soininen, H.7
Tuomilehto, J.8
Nissinen, A.9
-
36
-
-
26444463825
-
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
-
16216938 10.1001/archneur.62.10.1556
-
Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kareholt I, Winblad B, Helkala EL, Tuomilehto J, Soininen H, Nissinen A (2005) Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol 62:1556-1560
-
(2005)
Arch Neurol
, vol.62
, pp. 1556-1560
-
-
Kivipelto, M.1
Ngandu, T.2
Fratiglioni, L.3
Viitanen, M.4
Kareholt, I.5
Winblad, B.6
Helkala, E.L.7
Tuomilehto, J.8
Soininen, H.9
Nissinen, A.10
-
37
-
-
44049089850
-
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: A combined transcriptomics and metabolomics analysis
-
2375038 17892536 10.1186/gb-2007-8-9-r200
-
Kleemann R, Verschuren L, van Erk MJ, Nikolsky Y, Cnubben NH, Verheij ER, Smilde AK, Hendriks HF, Zadelaar S, Smith GS, Kaznacheev V, Nikolskaya T, Melnikov A, Hurt-Camejo E, van der Greef J, van Ommen B, Kooistra T (2007) Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biol 8(9):R200
-
(2007)
Genome Biol
, vol.8
, Issue.9
, pp. 200
-
-
Kleemann, R.1
Verschuren, L.2
Van Erk, M.J.3
Nikolsky, Y.4
Cnubben, N.H.5
Verheij, E.R.6
Smilde, A.K.7
Hendriks, H.F.8
Zadelaar, S.9
Smith, G.S.10
Kaznacheev, V.11
Nikolskaya, T.12
Melnikov, A.13
Hurt-Camejo, E.14
Van Der Greef, J.15
Van Ommen, B.16
Kooistra, T.17
-
38
-
-
0033993523
-
Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression
-
10627591
-
Li Y, Liu L, Kang J, Sheng JG, Barger SW, Mrak RE, Griffin WS (2000) Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J Neurosci 20:149-155
-
(2000)
J Neurosci
, vol.20
, pp. 149-155
-
-
Li, Y.1
Liu, L.2
Kang, J.3
Sheng, J.G.4
Barger, S.W.5
Mrak, R.E.6
Griffin, W.S.7
-
39
-
-
20444461628
-
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: Model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis
-
15826936 10.1074/jbc.M501759200
-
Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I (2005) Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. J Biol Chem 280:21763-21772
-
(2005)
J Biol Chem
, vol.280
, pp. 21763-21772
-
-
Li, Y.1
Schwabe, R.F.2
Devries-Seimon, T.3
Yao, P.M.4
Gerbod-Giannone, M.C.5
Tall, A.R.6
Davis, R.J.7
Flavell, R.8
Brenner, D.A.9
Tabas, I.10
-
40
-
-
0023255981
-
The use of a plus-maze to measure anxiety in the mouse
-
3110839
-
Lister RG (1987) The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 92:180-185
-
(1987)
Psychopharmacology
, vol.92
, pp. 180-185
-
-
Lister, R.G.1
-
42
-
-
84867854568
-
Green tea extract reverses endothelial dysfunction and reduces atherosclerosis progression in homozygous knockout low-density lipoprotein receptor mice
-
23084641 10.1016/j.nutres.2012.08.003
-
Minatti J, Wazlawik E, Hort MA, Zaleski FL, Ribeiro-do-Valle RM, Maraschin M, da Silva EL (2012) Green tea extract reverses endothelial dysfunction and reduces atherosclerosis progression in homozygous knockout low-density lipoprotein receptor mice. Nutr Res 32:684-693
-
(2012)
Nutr Res
, vol.32
, pp. 684-693
-
-
Minatti, J.1
Wazlawik, E.2
Hort, M.A.3
Zaleski, F.L.4
Ribeiro-Do-Valle, R.M.5
Maraschin, M.6
Da Silva, E.L.7
-
43
-
-
84869417613
-
Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?
-
3621365 22903822 10.1093/toxsci/kfs252
-
Moreira EL, de Oliveira J, Dutra MF, Santos DB, Goncalves CA, Goldfeder EM, de Bem AF, Prediger RD, Aschner M, Farina M (2012a) Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease? Toxicol Sci 130:373-382
-
(2012)
Toxicol Sci
, vol.130
, pp. 373-382
-
-
Moreira, E.L.1
De Oliveira, J.2
Dutra, M.F.3
Santos, D.B.4
Goncalves, C.A.5
Goldfeder, E.M.6
De Bem, A.F.7
Prediger, R.D.8
Aschner, M.9
Farina, M.10
-
44
-
-
84867557477
-
Age-related cognitive decline in hypercholesterolemic LDL receptor knockout mice (LDLr-/-): Evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex
-
22810096
-
Moreira EL, de Oliveira J, Nunes JC, Santos DB, Nunes FC, Vieira DS, Ribeiro-do-Valle RM, Pamplona FA, de Bem AF, Farina M, Walz R, Prediger RD (2012b) Age-related cognitive decline in hypercholesterolemic LDL receptor knockout mice (LDLr-/-): evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex. J Alzheimers Dis 32:495-511
-
(2012)
J Alzheimers Dis
, vol.32
, pp. 495-511
-
-
Moreira, E.L.1
De Oliveira, J.2
Nunes, J.C.3
Santos, D.B.4
Nunes, F.C.5
Vieira, D.S.6
Ribeiro-Do-Valle, R.M.7
Pamplona, F.A.8
De Bem, A.F.9
Farina, M.10
Walz, R.11
Prediger, R.D.12
-
45
-
-
84876409559
-
Effects of lifestyle modifications on cognitive impairments in a mouse model of hypercholesterolemia
-
23470631 10.1016/j.neulet.2013.02.043
-
Moreira EL, Aguiar AS Jr, de Carvalho CR, Santos DB, de Oliveira J, de Bem AF, Xikota JC, Walz R, Farina M, Prediger RD (2013) Effects of lifestyle modifications on cognitive impairments in a mouse model of hypercholesterolemia. Neurosci Lett 541:193-198
-
(2013)
Neurosci Lett
, vol.541
, pp. 193-198
-
-
Moreira, E.L.1
Aguiar, Jr.A.S.2
De Carvalho, C.R.3
Santos, D.B.4
De Oliveira, J.5
De Bem, A.F.6
Xikota, J.C.7
Walz, R.8
Farina, M.9
Prediger, R.D.10
-
46
-
-
33845497185
-
Characteristics of object location memory in mice: Behavioral and pharmacological studies
-
17049363 10.1016/j.physbeh.2006.09.013
-
Murai T, Okuda S, Tanaka T, Ohta H (2007) Characteristics of object location memory in mice: behavioral and pharmacological studies. Physiol Behav 90:116-124
-
(2007)
Physiol Behav
, vol.90
, pp. 116-124
-
-
Murai, T.1
Okuda, S.2
Tanaka, T.3
Ohta, H.4
-
47
-
-
9344269387
-
Aquaporin-4 in the central nervous system: Cellular and subcellular distribution and coexpression with KIR4.1
-
15561407 10.1016/j.neuroscience.2004.08.053
-
Nagelhus EA, Mathiisen TM, Ottersen OP (2004) Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1. Neuroscience 129:905-913
-
(2004)
Neuroscience
, vol.129
, pp. 905-913
-
-
Nagelhus, E.A.1
Mathiisen, T.M.2
Ottersen, O.P.3
-
48
-
-
9344249008
-
The role of aquaporin-4 in the blood-brain barrier development and integrity: Studies in animal and cell culture models
-
15561409 10.1016/j.neuroscience.2004.07.055
-
Nicchia GP, Nico B, Camassa LM, Mola MG, Loh N, Dermietzel R, Spray DC, Svelto M, Frigeri A (2004) The role of aquaporin-4 in the blood-brain barrier development and integrity: studies in animal and cell culture models. Neuroscience 129:935-945
-
(2004)
Neuroscience
, vol.129
, pp. 935-945
-
-
Nicchia, G.P.1
Nico, B.2
Camassa, L.M.3
Mola, M.G.4
Loh, N.5
Dermietzel, R.6
Spray, D.C.7
Svelto, M.8
Frigeri, A.9
-
49
-
-
0018384650
-
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
-
36810 10.1016/0003-2697(79)90738-3
-
Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358
-
(1979)
Anal Biochem
, vol.95
, pp. 351-358
-
-
Ohkawa, H.1
Ohishi, N.2
Yagi, K.3
-
50
-
-
0026178410
-
Alterations in some lipid components and Ca2+ ATPase activity in brain of rats fed an atherogenic diet
-
1835114
-
Oner P, Bekpinar S, Oz B (1991) Alterations in some lipid components and Ca2+ ATPase activity in brain of rats fed an atherogenic diet. Res Commun Chem Pathol Pharmacol 72:337-345
-
(1991)
Res Commun Chem Pathol Pharmacol
, vol.72
, pp. 337-345
-
-
Oner, P.1
Bekpinar, S.2
Oz, B.3
-
51
-
-
0037315747
-
The impact of systemic infection on the progression of neurodegenerative disease
-
12563281 10.1038/nrn1032
-
Perry VH, Newman TA, Cunningham C (2003) The impact of systemic infection on the progression of neurodegenerative disease. Nat Rev Neurosci 4:103-112
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 103-112
-
-
Perry, V.H.1
Newman, T.A.2
Cunningham, C.3
-
52
-
-
80051669613
-
Involvement of NMDA receptor complex in the anxiolytic-like effects of chlordiazepoxide in mice
-
3104009 21298298 10.1007/s00702-011-0585-x
-
Poleszak E, Socala K, Szopa A, Wróbel A, Szewczyk B, Kasperek R, Blicharska E, Nowak G, Wlaz P (2011) Involvement of NMDA receptor complex in the anxiolytic-like effects of chlordiazepoxide in mice. J Neural Transm 118:857-864
-
(2011)
J Neural Transm
, vol.118
, pp. 857-864
-
-
Poleszak, E.1
Socala, K.2
Szopa, A.3
Wróbel, A.4
Szewczyk, B.5
Kasperek, R.6
Blicharska, E.7
Nowak, G.8
Wlaz, P.9
-
53
-
-
0017618768
-
Depression: A new animal model sensitive to antidepressant treatments
-
559941 10.1038/266730a0
-
Porsolt RD, Le Pichon M, Jalfre M (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature 266:730-732
-
(1977)
Nature
, vol.266
, pp. 730-732
-
-
Porsolt, R.D.1
Le Pichon, M.2
Jalfre, M.3
-
54
-
-
84864338340
-
Vitamin e slows the progression of hypercholesterolemia-induced oxidative stress in heart, liver and kidney
-
22714834 10.1007/s11010-012-1358-z
-
Prasad K, McNair ED, Qureshi AM, Casper-Bell G (2012) Vitamin E slows the progression of hypercholesterolemia-induced oxidative stress in heart, liver and kidney. Mol Cell Biochem 368:181-187
-
(2012)
Mol Cell Biochem
, vol.368
, pp. 181-187
-
-
Prasad, K.1
McNair, E.D.2
Qureshi, A.M.3
Casper-Bell, G.4
-
55
-
-
84865018923
-
Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases
-
22212484 10.1007/s00702-011-0758-7
-
Ramalingam M, Kim S (2012) Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases. J Neural Transm 119:891-910
-
(2012)
J Neural Transm
, vol.119
, pp. 891-910
-
-
Ramalingam, M.1
Kim, S.2
-
56
-
-
49849104853
-
Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition
-
18566307 10.1161/STROKEAHA.107.496737
-
Rapp JH, Pan XM, Neumann M, Hong M, Hollenbeck K, Liu J (2008) Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition. Stroke 39:2354-2361
-
(2008)
Stroke
, vol.39
, pp. 2354-2361
-
-
Rapp, J.H.1
Pan, X.M.2
Neumann, M.3
Hong, M.4
Hollenbeck, K.5
Liu, J.6
-
57
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
10964604 10.1006/nbdi.2000.0304
-
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA (2000) Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7:321-331
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
Lafrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
Sambamurti, K.7
Duff, K.8
Pappolla, M.A.9
-
58
-
-
84856538233
-
Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid beta peptide in mice
-
22173317 10.1016/j.expneurol.2011.11.036
-
Santos DB, Peres KC, Ribeiro RP, Colle D, dos Santos AA, Moreira EL, Souza DO, Figueiredo CP, Farina M (2012) Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid beta peptide in mice. Exp Neurol 233:767-775
-
(2012)
Exp Neurol
, vol.233
, pp. 767-775
-
-
Santos, D.B.1
Peres, K.C.2
Ribeiro, R.P.3
Colle, D.4
Dos Santos, A.A.5
Moreira, E.L.6
Souza, D.O.7
Figueiredo, C.P.8
Farina, M.9
-
59
-
-
79955038570
-
Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
-
3073459 21335619 10.1194/jlr.M014548
-
Shafaati M, Marutle A, Pettersson H, Lovgren-Sandblom A, Olin M, Pikuleva I, Winblad B, Nordberg A, Bjorkhem I (2011) Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation. J Lipid Res 52:1004-1010
-
(2011)
J Lipid Res
, vol.52
, pp. 1004-1010
-
-
Shafaati, M.1
Marutle, A.2
Pettersson, H.3
Lovgren-Sandblom, A.4
Olin, M.5
Pikuleva, I.6
Winblad, B.7
Nordberg, A.8
Bjorkhem, I.9
-
60
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
27798 9600988 10.1073/pnas.95.11.6460
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K (1998) Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci USA 95:6460-6464
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
61
-
-
67749114631
-
Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
-
2814023 19648749 10.1159/000231980
-
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA (2009) Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later. Dement Geriatr Cogn Disord 28:75-80
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, pp. 75-80
-
-
Solomon, A.1
Kivipelto, M.2
Wolozin, B.3
Zhou, J.4
Whitmer, R.A.5
-
62
-
-
0035320772
-
Acetylcholinesterase - New roles for an old actor
-
11283752 10.1038/35067589
-
Soreq H, Seidman S (2001) Acetylcholinesterase - new roles for an old actor. Nat Rev Neurosci 2:294-302
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 294-302
-
-
Soreq, H.1
Seidman, S.2
-
63
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
8157129 10.1006/exnr.1994.1044
-
Sparks DL, Scheff SW, Hunsaker JC 3rd, Liu H, Landers T, Gross DR (1994) Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126:88-94
-
(1994)
Exp Neurol
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker III, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
64
-
-
0034098980
-
Alterations of Alzheimer's disease in the cholesterol-fed rabbit, including vascular inflammation. Preliminary observations
-
10818523 10.1111/j.1749-6632.2000.tb06384.x
-
Sparks DL, Kuo YM, Roher A, Martin T, Lukas RJ (2000) Alterations of Alzheimer's disease in the cholesterol-fed rabbit, including vascular inflammation. Preliminary observations. Ann N Y Acad Sci 903:335-344
-
(2000)
Ann N y Acad Sci
, vol.903
, pp. 335-344
-
-
Sparks, D.L.1
Kuo, Y.M.2
Roher, A.3
Martin, T.4
Lukas, R.J.5
-
65
-
-
76549086709
-
Dietary fats, cerebrovasculature integrity and Alzheimer's disease risk
-
19896503 10.1016/j.plipres.2009.10.004
-
Takechi R, Galloway S, Pallebage-Gamarallage MM, Lam V, Mamo JC (2010) Dietary fats, cerebrovasculature integrity and Alzheimer's disease risk. Prog Lipid Res 49:159-170
-
(2010)
Prog Lipid Res
, vol.49
, pp. 159-170
-
-
Takechi, R.1
Galloway, S.2
Pallebage-Gamarallage, M.M.3
Lam, V.4
Mamo, J.C.5
-
66
-
-
45249117903
-
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
-
3897170 18410513 10.1111/j.1471-4159.2008.05415.x
-
Thirumangalakudi L, Prakasam A, Zhang R, Bimonte-Nelson H, Sambamurti K, Kindy MS, Bhat NR (2008) High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J Neurochem 106:475-485
-
(2008)
J Neurochem
, vol.106
, pp. 475-485
-
-
Thirumangalakudi, L.1
Prakasam, A.2
Zhang, R.3
Bimonte-Nelson, H.4
Sambamurti, K.5
Kindy, M.S.6
Bhat, N.R.7
-
67
-
-
18744386421
-
Blood-brain barrier disruption highly induces aquaporin-4 mRNA and protein in perivascular and parenchymal astrocytes: Protective effect by estradiol treatment in ovariectomized animals
-
15772982 10.1002/jnr.20443
-
Tomas-Camardiel M, Venero JL, Herrera AJ, De Pablos RM, Pintor-Toro JA, Machado A, Cano J (2005) Blood-brain barrier disruption highly induces aquaporin-4 mRNA and protein in perivascular and parenchymal astrocytes: protective effect by estradiol treatment in ovariectomized animals. J Neurosci Res 80:235-246
-
(2005)
J Neurosci Res
, vol.80
, pp. 235-246
-
-
Tomas-Camardiel, M.1
Venero, J.L.2
Herrera, A.J.3
De Pablos, R.M.4
Pintor-Toro, J.A.5
MacHado, A.6
Cano, J.7
-
68
-
-
77957959900
-
Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits
-
2977849 20696249 10.1016/j.mcn.2010.08.001
-
Ullrich C, Pirchl M, Humpel C (2010) Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits. Mol Cell Neurosci 45:408-417
-
(2010)
Mol Cell Neurosci
, vol.45
, pp. 408-417
-
-
Ullrich, C.1
Pirchl, M.2
Humpel, C.3
-
69
-
-
84862997074
-
Cholesterol and late-life cognitive decline
-
22269162
-
van Vliet P (2012) Cholesterol and late-life cognitive decline. J Alzheimers Dis 30(Suppl 2):S147-S162
-
(2012)
J Alzheimers Dis
, vol.30
, Issue.SUPPL. 2
-
-
Van Vliet, P.1
-
70
-
-
57349085740
-
The influence of age on the association between cholesterol and cognitive function
-
18579327 10.1016/j.exger.2008.05.004
-
van Vliet P, van de Water W, de Craen AJ, Westendorp RG (2009) The influence of age on the association between cholesterol and cognitive function. Exp Gerontol 44:112-122
-
(2009)
Exp Gerontol
, vol.44
, pp. 112-122
-
-
Van Vliet, P.1
Van De Water, W.2
De Craen, A.J.3
Westendorp, R.G.4
-
71
-
-
77953280950
-
Membrane rafts in Alzheimer's disease beta-amyloid production
-
2886169 20303415 10.1016/j.bbalip.2010.03.007
-
Vetrivel KS, Thinakaran G (2010) Membrane rafts in Alzheimer's disease beta-amyloid production. Biochim Biophys Acta 1801:860-867
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 860-867
-
-
Vetrivel, K.S.1
Thinakaran, G.2
-
72
-
-
0019740344
-
Glutathione peroxidase
-
7329310 10.1016/S0076-6879(81)77046-0
-
Wendel A (1981) Glutathione peroxidase. Methods Enzymol 77:325-333
-
(1981)
Methods Enzymol
, vol.77
, pp. 325-333
-
-
Wendel, A.1
-
73
-
-
0035943450
-
The brain's susceptibility to amyloid plaques
-
11526940 10.1126/science.293.5534.1434b
-
Wong PC, Price DL, Cai H (2001) The brain's susceptibility to amyloid plaques. Science 293:1434
-
(2001)
Science
, vol.293
, pp. 1434
-
-
Wong, P.C.1
Price, D.L.2
Cai, H.3
-
74
-
-
77955516737
-
PRiMA directs a restricted localization of tetrameric AChE at synapses
-
20178777 10.1016/j.cbi.2010.02.018
-
Xie HQ, Leung KW, Chen VP, Chan GK, Xu SL, Guo AJ, Zhu KY, Zheng KY, Bi CW, Zhan JY, Chan WK, Choi RC, Tsim KW (2010a) PRiMA directs a restricted localization of tetrameric AChE at synapses. Chem Biol Interact 187:78-83
-
(2010)
Chem Biol Interact
, vol.187
, pp. 78-83
-
-
Xie, H.Q.1
Leung, K.W.2
Chen, V.P.3
Chan, G.K.4
Xu, S.L.5
Guo, A.J.6
Zhu, K.Y.7
Zheng, K.Y.8
Bi, C.W.9
Zhan, J.Y.10
Chan, W.K.11
Choi, R.C.12
Tsim, K.W.13
-
75
-
-
77951234310
-
Targeting acetylcholinesterase to membrane rafts: A function mediated by the proline-rich membrane anchor (PRiMA) in neurons
-
2857032 20147288 10.1074/jbc.M109.038711
-
Xie HQ, Liang D, Leung KW, Chen VP, Zhu KY, Chan WK, Choi RC, Massoulie J, Tsim KW (2010b) Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. J Biol Chem 285:11537-11546
-
(2010)
J Biol Chem
, vol.285
, pp. 11537-11546
-
-
Xie, H.Q.1
Liang, D.2
Leung, K.W.3
Chen, V.P.4
Zhu, K.Y.5
Chan, W.K.6
Choi, R.C.7
Massoulie, J.8
Tsim, K.W.9
-
76
-
-
39249084075
-
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production
-
2720683 18086530 10.1016/j.nbd.2007.10.005
-
Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG, Sue LI, Woulfe J, Xu H, Stanimirovic DB, Zhang W (2008) Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production. Neurobiol Dis 29:422-437
-
(2008)
Neurobiol Dis
, vol.29
, pp. 422-437
-
-
Xiong, H.1
Callaghan, D.2
Jones, A.3
Walker, D.G.4
Lue, L.F.5
Beach, T.G.6
Sue, L.I.7
Woulfe, J.8
Xu, H.9
Stanimirovic, D.B.10
Zhang, W.11
|