Age-Related cognitive decline in hypercholesterolemic LDL receptor knockout mice (LDLr-/-): Evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex

Journal of Alzheimer's Disease

Volumn 32, Issue 2, 2012, Pages 495-511

  Moreira, Eduardo Luiz Gasnhar ^a   De Oliveira, Jade ^a   Nunes, Jean Costa ^a   Santos, Danúbia Bonfanti ^a   Nunes, Fernanda Costa ^a   Vieira, Daniella Serafim Couto ^a   Ribeiro Do Valle, Rosa Maria ^a   Pamplona, Fabrício Alano ^a   De Bem, Andreza Fabro ^a   Farina, Marcelo ^a   Walz, Roger ^a   Prediger, Rui Daniel ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Acetylcholinesterase activity; aging; cognitive deficits; LDL receptor knockout mice (LDLr ( rm minus minus ) ); oxidative stress

Indexed keywords

ACETYLCHOLINESTERASE; ANTIOXIDANT; LOW DENSITY LIPOPROTEIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREFRONTAL CORTEX; PRIORITY JOURNAL;

EID: 84867557477     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120541     Document Type: Article

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