Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 11, 2015, Pages E1181-E1190

  Hillenbrand, Matthias ^a   Schori, Christian ^a   Schöppe, Jendrik ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

G protein coupled receptor; Heterotrimeric G proteins; Membrane protein; Protein complex; Protein protein interaction

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HEMAGGLUTININ; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LEUCINE; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR 1; UNCLASSIFIED DRUG; MUTANT PROTEIN; PROTEIN BINDING; SOLUTION AND SOLUBILITY;

AGONIST; ALPHA CHAIN; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLIZATION; DRUG DESIGN; GENE MUTATION; HUMAN; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SUBUNIT; RECEPTOR BINDING; RECEPTOR SOLUBILIZATION; WILD TYPE; ANIMAL; ISOLATION AND PURIFICATION; METABOLISM; SF9 CELL LINE; SIZE EXCLUSION CHROMATOGRAPHY; SOLUTION AND SOLUBILITY;

ANIMALS; CHROMATOGRAPHY, GEL; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MUTANT PROTEINS; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SF9 CELLS; SOLUTIONS;

EID: 84925238961     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417573112     Document Type: Article

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