Influence of differential stability of G protein βγ dimers containing the γ11 subunit on functional activity at the M 1 muscarinic receptor, A1 adenosine receptor, and phospholipase C-β+

Biochemistry

Volumn 45, Issue 38, 2006, Pages 11616-11631

  McIntire, William E ^a   MacCleery, Gavin ^a   Murphree, Lauren J ^b   Kerchner, Kristi R ^a   Linden, Joel ^b   Garrison, James C ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b Department of Medicine and Pharmacology ^*

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; DIMERS; DISSOCIATION; ENZYME KINETICS; LIPIDS; STABILITY;

DENATURATION; GUANINE; NUCLEOTIDE-BINDING REGULATORY PROTEIN; PROTEIN ACTIVITY;

PROTEINS;

8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A1 RECEPTOR ANTAGONIST; DIMER; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); IODINE 125; MAGNESIUM CHLORIDE; MUSCARINIC M1 RECEPTOR; N6 (4 AMINO 3 BENZYL)ADENOSINE; PHOSPHOLIPASE C; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN; SULFUR 35; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACULOVIRUS; BINDING AFFINITY; DIMERIZATION; GEL FILTRATION CHROMATOGRAPHY; MEMBRANE BINDING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT;

ANIMALS; ANTIBODIES; BINDING SITES; DIMERIZATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; ISOENZYMES; PHOSPHOLIPASE C; PRECIPITATION; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN SUBUNITS; RECEPTOR, ADENOSINE A1; RECEPTOR, MUSCARINIC M1; RECOMBINANT PROTEINS; SPODOPTERA; THERMODYNAMICS; TURKEYS;

EID: 33749038655     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0604882     Document Type: Article

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