-
1
-
-
80053615320
-
The significance of G protein-coupled receptor crystallography for drug discovery
-
J.A. Salon, D.T. Lodowski, and K. Palczewski The significance of G protein-coupled receptor crystallography for drug discovery Pharmacol. Rev. 63 2011 901 937
-
(2011)
Pharmacol. Rev.
, vol.63
, pp. 901-937
-
-
Salon, J.A.1
Lodowski, D.T.2
Palczewski, K.3
-
2
-
-
33947172767
-
Detergents for the stabilization and crystallization of membrane proteins
-
G.G. Prive Detergents for the stabilization and crystallization of membrane proteins Methods 41 2007 388 397
-
(2007)
Methods
, vol.41
, pp. 388-397
-
-
Prive, G.G.1
-
3
-
-
69249146075
-
Engineering G protein-coupled receptors to facilitate their structure determination
-
C.G. Tate, and G.F. Schertler Engineering G protein-coupled receptors to facilitate their structure determination Curr. Opin. Struct. Biol. 19 2009 386 395
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 386-395
-
-
Tate, C.G.1
Schertler, G.F.2
-
4
-
-
0027143565
-
Val → Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein
-
C.M. Deber, A.R. Khan, Z. Li, C. Joensson, M. Glibowicka, and J. Wang Val → Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein Proc. Natl Acad. Sci. USA 90 1993 11648 11652
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 11648-11652
-
-
Deber, C.M.1
Khan, A.R.2
Li, Z.3
Joensson, C.4
Glibowicka, M.5
Wang, J.6
-
5
-
-
0030745896
-
+ channel (SKC1): Oligomeric stoichiometry and stability
-
+ channel (SKC1): oligomeric stoichiometry and stability Biochemistry 36 1997 10343 10352
-
(1997)
Biochemistry
, vol.36
, pp. 10343-10352
-
-
Cortes, D.M.1
Perozo, E.2
-
7
-
-
0033538418
-
Changing single side-chains can greatly enhance the resistance of a membrane protein to irreversible inactivation
-
F.W. Lau, S. Nauli, Y. Zhou, and J.U. Bowie Changing single side-chains can greatly enhance the resistance of a membrane protein to irreversible inactivation J. Mol. Biol. 290 1999 559 564
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 559-564
-
-
Lau, F.W.1
Nauli, S.2
Zhou, Y.3
Bowie, J.U.4
-
8
-
-
0034717063
-
Peptide mimics of the M13 coat protein transmembrane segment. Retention of helix-helix interaction motifs
-
C. Wang, and C.M. Deber Peptide mimics of the M13 coat protein transmembrane segment. Retention of helix-helix interaction motifs J. Biol. Chem. 275 2000 16155 16159
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16155-16159
-
-
Wang, C.1
Deber, C.M.2
-
9
-
-
0034629489
-
Building a thermostable membrane protein
-
Y. Zhou, and J.U. Bowie Building a thermostable membrane protein J. Biol. Chem. 275 2000 6975 6979
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6975-6979
-
-
Zhou, Y.1
Bowie, J.U.2
-
10
-
-
0035423934
-
Stabilizing membrane proteins
-
J.U. Bowie Stabilizing membrane proteins Curr. Opin. Struct. Biol. 11 2001 397 402
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 397-402
-
-
Bowie, J.U.1
-
11
-
-
34548529916
-
Crystal structure of a thermally stable rhodopsin mutant
-
J. Standfuss, G. Xie, P.C. Edwards, M. Burghammer, D.D. Oprian, and G.F. Schertler Crystal structure of a thermally stable rhodopsin mutant J. Mol. Biol. 372 2007 1179 1188
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 1179-1188
-
-
Standfuss, J.1
Xie, G.2
Edwards, P.C.3
Burghammer, M.4
Oprian, D.D.5
Schertler, G.F.6
-
12
-
-
49449114407
-
Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor
-
F. Magnani, Y. Shibata, M.J. Serrano-Vega, and C.G. Tate Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor Proc. Natl Acad. Sci. USA 105 2008 10744 10749
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 10744-10749
-
-
Magnani, F.1
Shibata, Y.2
Serrano-Vega, M.J.3
Tate, C.G.4
-
14
-
-
54449087770
-
Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity
-
C.A. Sarkar, I. Dodevski, M. Kenig, S. Dudli, A. Mohr, E. Hermans, and A. Plückthun Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity Proc. Natl Acad. Sci. USA 105 2008 14808 14813
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 14808-14813
-
-
Sarkar, C.A.1
Dodevski, I.2
Kenig, M.3
Dudli, S.4
Mohr, A.5
Hermans, E.6
Plückthun, A.7
-
16
-
-
67349173167
-
Thermostabilization of the neurotensin receptor NTS1
-
Y. Shibata, J.F. White, M.J. Serrano-Vega, F. Magnani, A.L. Aloia, R. Grisshammer, and C.G. Tate Thermostabilization of the neurotensin receptor NTS1 J. Mol. Biol. 390 2009 262 277
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 262-277
-
-
Shibata, Y.1
White, J.F.2
Serrano-Vega, M.J.3
Magnani, F.4
Aloia, A.L.5
Grisshammer, R.6
Tate, C.G.7
-
17
-
-
79955021788
-
Evolution of three human GPCRs for higher expression and stability
-
I. Dodevski, and A. Plückthun Evolution of three human GPCRs for higher expression and stability J. Mol. Biol. 408 2011 599 615
-
(2011)
J. Mol. Biol.
, vol.408
, pp. 599-615
-
-
Dodevski, I.1
Plückthun, A.2
-
18
-
-
78149501282
-
The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery
-
N. Robertson, A. Jazayeri, J. Errey, A. Baig, E. Hurrell, and A. Zhukov The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery Neuropharmacology 60 2011 36 44
-
(2011)
Neuropharmacology
, vol.60
, pp. 36-44
-
-
Robertson, N.1
Jazayeri, A.2
Errey, J.3
Baig, A.4
Hurrell, E.5
Zhukov, A.6
-
19
-
-
84862546176
-
Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-All mutations
-
K.M. Schlinkmann, A. Honegger, E. Tureci, K.E. Robison, D. Lipovsek, and A. Plückthun Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-All mutations Proc. Natl Acad. Sci. USA 109 2012 9810 9815
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 9810-9815
-
-
Schlinkmann, K.M.1
Honegger, A.2
Tureci, E.3
Robison, K.E.4
Lipovsek, D.5
Plückthun, A.6
-
20
-
-
84865158745
-
Naturally evolved G protein-coupled receptors adopt metastable conformations
-
K.Y. Chen, F. Zhou, B.G. Fryszczyn, and P. Barth Naturally evolved G protein-coupled receptors adopt metastable conformations Proc. Natl Acad. Sci. USA 109 2012 13284 13289
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13284-13289
-
-
Chen, K.Y.1
Zhou, F.2
Fryszczyn, B.G.3
Barth, P.4
-
21
-
-
84865068808
-
Maximizing detergent stability and functional expression of a GPCR by exhaustive recombination and evolution
-
K.M. Schlinkmann, M. Hillenbrand, A. Rittner, M. Kunz, R. Strohner, and A. Plückthun Maximizing detergent stability and functional expression of a GPCR by exhaustive recombination and evolution J. Mol. Biol. 422 2012 414 428
-
(2012)
J. Mol. Biol.
, vol.422
, pp. 414-428
-
-
Schlinkmann, K.M.1
Hillenbrand, M.2
Rittner, A.3
Kunz, M.4
Strohner, R.5
Plückthun, A.6
-
22
-
-
79960156006
-
Biophysical mapping of the adenosine A2A receptor
-
A. Zhukov, S.P. Andrews, J.C. Errey, N. Robertson, B. Tehan, and J.S. Mason Biophysical mapping of the adenosine A2A receptor J. Med. Chem. 54 2011 4312 4323
-
(2011)
J. Med. Chem.
, vol.54
, pp. 4312-4323
-
-
Zhukov, A.1
Andrews, S.P.2
Errey, J.C.3
Robertson, N.4
Tehan, B.5
Mason, J.S.6
-
23
-
-
79952382815
-
Fragment screening of stabilized G-protein-coupled receptors using biophysical methods
-
M. Congreve, R.L. Rich, D.G. Myszka, F. Figaroa, G. Siegal, and F.H. Marshall Fragment screening of stabilized G-protein-coupled receptors using biophysical methods Methods Enzymol. 493 2011 115 136
-
(2011)
Methods Enzymol.
, vol.493
, pp. 115-136
-
-
Congreve, M.1
Rich, R.L.2
Myszka, D.G.3
Figaroa, F.4
Siegal, G.5
Marshall, F.H.6
-
25
-
-
79959564813
-
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
-
G. Lebon, T. Warne, P.C. Edwards, K. Bennett, C.J. Langmead, A.G. Leslie, and C.G. Tate Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation Nature 474 2011 521 525
-
(2011)
Nature
, vol.474
, pp. 521-525
-
-
Lebon, G.1
Warne, T.2
Edwards, P.C.3
Bennett, K.4
Langmead, C.J.5
Leslie, A.G.6
Tate, C.G.7
-
26
-
-
0037173305
-
Single living cell encapsulation in nano-organized polyelectrolyte shells
-
A. Diaspro, D. Silvano, S. Krol, O. Cavalleri, and A. Gliozzi Single living cell encapsulation in nano-organized polyelectrolyte shells Langmuir 18 2002 4
-
(2002)
Langmuir
, vol.18
, pp. 4
-
-
Diaspro, A.1
Silvano, D.2
Krol, S.3
Cavalleri, O.4
Gliozzi, A.5
-
27
-
-
33750312165
-
Biorecognition through layer-by-layer polyelectrolyte assembly: In-situ hybridization on living cells
-
A.L. Hillberg, and M. Tabrizian Biorecognition through layer-by-layer polyelectrolyte assembly: in-situ hybridization on living cells Biomacromolecules 7 2006 2742 2750
-
(2006)
Biomacromolecules
, vol.7
, pp. 2742-2750
-
-
Hillberg, A.L.1
Tabrizian, M.2
-
28
-
-
38049112372
-
PH-controlled construction of chitosan/alginate multilayer film: Characterization and application for antibody immobilization
-
W. Yuan, H. Dong, C.M. Li, X. Cui, L. Yu, Z. Lu, and Q. Zhou pH-controlled construction of chitosan/alginate multilayer film: characterization and application for antibody immobilization Langmuir 23 2007 13046 13052
-
(2007)
Langmuir
, vol.23
, pp. 13046-13052
-
-
Yuan, W.1
Dong, H.2
Li, C.M.3
Cui, X.4
Yu, L.5
Lu, Z.6
Zhou, Q.7
-
30
-
-
52949102889
-
Crystal structure of opsin in its G-protein-interacting conformation
-
P. Scheerer, J.H. Park, P.W. Hildebrand, Y.J. Kim, N. Krauss, and H.W. Choe Crystal structure of opsin in its G-protein-interacting conformation Nature 455 2008 497 502
-
(2008)
Nature
, vol.455
, pp. 497-502
-
-
Scheerer, P.1
Park, J.H.2
Hildebrand, P.W.3
Kim, Y.J.4
Krauss, N.5
Choe, H.W.6
-
31
-
-
33747130345
-
Miniaturising the laboratory in emulsion droplets
-
A.D. Griffiths, and D.S. Tawfik Miniaturising the laboratory in emulsion droplets Trends Biotechnol. 24 2006 395 402
-
(2006)
Trends Biotechnol.
, vol.24
, pp. 395-402
-
-
Griffiths, A.D.1
Tawfik, D.S.2
|