Regulatory T cell reprogramming toward a Th2-Cell-like lineage impairs oral tolerance and promotes food allergy

Immunity

Volumn 42, Issue 3, 2015, Pages 512-523

  NovalRivas, Magali ^a,b   Burton, Oliver T ^a,b   Wise, Petra ^c   Charbonnier, Louis Marie ^a,b   Georgiev, Peter ^a   Oettgen, Hans C ^a,b   Rachid, Rima ^a   Chatila, Talal A ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; STAT6 PROTEIN; CELL SURFACE RECEPTOR; IL4RA PROTEIN, MOUSE; STAT6 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LINEAGE; CHILD; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FOOD ALLERGY; GENE DELETION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INFANT; MALE; MAST CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH2 CELL; ANIMAL; DEFICIENCY; GASTRIC MUCOSA; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MUCOSAL IMMUNITY; PATHOLOGY; PRESCHOOL CHILD; TRANSGENIC MOUSE;

ADOLESCENT; ALLERGENS; ANIMALS; CELLULAR REPROGRAMMING; CHILD; CHILD, PRESCHOOL; FEMALE; FOOD HYPERSENSITIVITY; GASTRIC MUCOSA; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNE TOLERANCE; IMMUNITY, MUCOSAL; INFANT; INTERLEUKIN-13; INTERLEUKIN-4; MALE; MAST CELLS; MICE; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84925038493     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.02.004     Document Type: Article

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