Transfection system of amino-functionalized calcium phosphate nanoparticles: In vitro efficacy, biodegradability, and immunogenicity study

ACS Applied Materials and Interfaces

Volumn 7, Issue 9, 2015, Pages 5124-5133

  Mostaghaci, Babak ^a   Susewind, Julia ^b   Kickelbick, Guido ^b   Lehr, Claus Michael ^a,b   Loretz, Brigitta ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

aminosilane; biodegradation; complement activation; cytokine release; gene delivery; nucleotides

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABILITY; BIODEGRADATION; CALCIUM PHOSPHATE; CELL CULTURE; CHEMICAL ACTIVATION; CRYSTALS; DISINTEGRATION; GENE TRANSFER; HYDROXYAPATITE; NANOPARTICLES; NUCLEOTIDES;

AMINOPROPYLTRIMETHOXYSILANE; AMINOSILANES; CALCIUM PHOSPHATE NANOPARTICLES; COMPLEMENT ACTIVATIONS; CONFOCAL LASER SCANNING MICROSCOPY; CYTOKINES; GENE DELIVERY; PRO-INFLAMMATORY CYTOKINES;

CELLS;

3-AMINOPROPYLTRIMETHOXYSILANE; AMINE; BIOMATERIAL; CALCIUM PHOSPHATE; CYTOKINE; NANOPARTICLE; PROPYLAMINE; SILANE DERIVATIVE;

CELL LINE; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; ERYTHROCYTE; GENETIC TRANSFECTION; HEK293 CELL LINE; HEMOLYSIS; HUMAN; IMMUNOLOGY; METABOLISM; PH;

AMINES; BIOCOMPATIBLE MATERIALS; CALCIUM PHOSPHATES; CELL LINE; CELL SURVIVAL; CYTOKINES; ERYTHROCYTES; HEK293 CELLS; HEMOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, CONFOCAL; NANOPARTICLES; PROPYLAMINES; SILANES; TRANSFECTION;

EID: 84924598934     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am507193a     Document Type: Article

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