Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery

Biomaterials

Volumn 34, Issue 9, 2013, Pages 2340-2349

  Yin, Lichen ^a   Song, Ziyuan ^a   Kim, Kyung Hoon ^a   Zheng, Nan ^a   Tang, Haoyu ^a   Lu, Hua ^a   Gabrielson, Nathan ^a   Cheng, Jianjun ^a  

^a University of Illinois at Urbana Champaign   (United States)

Author keywords

Cationic helical polypeptide; Cell penetrating peptide (CPP); Macromolecular architecture; Non viral gene delivery; PEGylation

Indexed keywords

CELL-PENETRATING PEPTIDE; HELICAL POLYPEPTIDES; MACROMOLECULAR ARCHITECTURE; NON-VIRAL GENE DELIVERY; PEGYLATION;

BINDING ENERGY; BLOCK COPOLYMERS; CYTOTOXICITY; EFFICIENCY; GENE TRANSFER; GENES; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); LIPOSOMES; MOLECULAR BIOLOGY; POLYETHYLENE OXIDES; POLYPEPTIDES;

POLYETHYLENE GLYCOLS;

CELL DNA; COPOLYMER; MACROGOL; POLY[GAMMA 4 [[2 (PIPERIDIN 1 YL)ETHYL]AMINOMETHYL]BENZYL LEVO GLUTAMATE]; POLYPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL STRAIN HEPG2; CELL VIABILITY; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; NONVIRAL GENE DELIVERY SYSTEM; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FOLDING; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE; RING OPENING;

CATIONS; CELL SURVIVAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HEP G2 CELLS; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PEPTIDES; POLYMERS; TRANSFECTION;

EID: 84872407943     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.11.064     Document Type: Article

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