Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

PLoS Genetics

Volumn 11, Issue 2, 2015, Pages 1-24

  Schaar, Claire E ^a   Dues, Dylan J ^a   Spielbauer, Katie K ^a   Machiela, Emily ^a   Cooper, Jason F ^a   Senchuk, Megan ^a   Hekimi, Siegfried ^d   Van Raamsdonk, Jeremy M ^a,b,c,d  

^a VAN ANDEL RESEARCH INSTITUTE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PARAQUAT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; CAENORHABDITIS ELEGANS PROTEIN; ISP-1 PROTEIN, CAENORHABDITIS ELEGANS; NDUFB4 PROTEIN, C ELEGANS; SOD-1 PROTEIN, C ELEGANS; UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CELL COMPONENT; CELL COMPOSITION; CLK 1 GENE; CONTROLLED STUDY; CYTOPLASM; GENE; GENE DELETION; LIFESPAN; MITOCHONDRION; NONHUMAN; SOD 1 GENE; SOD 2 GENE; SOD 5 GENE; SOD GENE; YOUNG ADULT; AGING; ANIMAL; CAENORHABDITIS ELEGANS; ELECTRON TRANSPORT; GENETICS; LONGEVITY; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX III; LONGEVITY; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 84924362186     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004972     Document Type: Article

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